메뉴 건너뛰기




Volumn 22, Issue 2, 2010, Pages 459-468

Cerebrospinal fluid markers for alzheimer's disease over the lifespan: Effects of age and the APOEε4 genotype

Author keywords

Alzheimer's disease; amyloid ; APOE 4; cerebrospinal fluid; hyperphosphorylated tau; normal aging

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; APOLIPOPROTEIN E4; TAU PHOSPHORYLATED AT THREONINE 181; TAU PROTEIN; UNCLASSIFIED DRUG;

EID: 78650846588     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-100561     Document Type: Article
Times cited : (31)

References (32)
  • 3
    • 33947223454 scopus 로고    scopus 로고
    • Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults
    • Fagan AM, Roe CM, Xiong C, Mintun MA, Morris JC, Holtzman DM (2007) Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults. Arch Neurol 64, 343-349.
    • (2007) Arch Neurol , vol.64 , pp. 343-349
    • Fagan, A.M.1    Roe, C.M.2    Xiong, C.3    Mintun, M.A.4    Morris, J.C.5    Holtzman, D.M.6
  • 5
    • 32544435900 scopus 로고    scopus 로고
    • Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: A follow-up study
    • Hansson O, Zetterberg H, Buchhave P, Londos E, Blennow K, Minthon L (2006) Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study. Lancet Neurol 5, 228-234.
    • (2006) Lancet Neurol , vol.5 , pp. 228-234
    • Hansson, O.1    Zetterberg, H.2    Buchhave, P.3    Londos, E.4    Blennow, K.5    Minthon, L.6
  • 7
    • 33645808672 scopus 로고    scopus 로고
    • Apolipoprotein E4: A causative factor and therapeutic target in neuropatholo-gy, including Alzheimer's disease
    • Mahley RW, Weisgraber KH, Huang Y (2006) Apolipoprotein E4: a causative factor and therapeutic target in neuropatholo-gy, including Alzheimer's disease. Proc Natl Acad Sci U SA 103, 5644-5651.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 5644-5651
    • Mahley, R.W.1    Weisgraber, K.H.2    Huang, Y.3
  • 8
    • 2442419100 scopus 로고    scopus 로고
    • Apolipoprotein e epsilon4 count affects age at onset of Alzheimer disease, but not lifetime susceptibility: The Cache County Study
    • Khachaturian AS, Corcoran CD, Mayer LS, Zandi PP, Breitner JC (2004) Apolipoprotein E epsilon4 count affects age at onset of Alzheimer disease, but not lifetime susceptibility: The Cache County Study. Arch Gen Psychiatry 61, 518-524.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 518-524
    • Khachaturian, A.S.1    Corcoran, C.D.2    Mayer, L.S.3    Zandi, P.P.4    Breitner, J.C.5
  • 9
    • 2542502430 scopus 로고    scopus 로고
    • ApoE genotype accounts for the vast majority of AD risk and AD pathology
    • Raber J, Huang Y, Ashford JW (2004) ApoE genotype accounts for the vast majority of AD risk and AD pathology. Neurobiol Aging 25, 641-650.
    • (2004) Neurobiol Aging , vol.25 , pp. 641-650
    • Raber, J.1    Huang, Y.2    Ashford, J.W.3
  • 13
    • 0034282184 scopus 로고    scopus 로고
    • Relationship between apoE genotype and CSF beta-amyloid (1-42) and tau in patients with probable and definite Alzheimer's disease
    • Tapiola T, Pirttila T, Mehta PD, Alafuzoff I, Lehtovirta M, Soininen H (2000) Relationship between apoE genotype and CSF beta-amyloid (1-42) and tau in patients with probable and definite Alzheimer's disease. Neurobiol Aging 21, 735-740.
    • (2000) Neurobiol Aging , vol.21 , pp. 735-740
    • Tapiola, T.1    Pirttila, T.2    Mehta, P.D.3    Alafuzoff, I.4    Lehtovirta, M.5    Soininen, H.6
  • 14
    • 2942557310 scopus 로고    scopus 로고
    • APOE epsilon4 allele is associated with reduced cerebrospinal fluid levels of Abeta
    • Prince JA, Zetterberg H, Andreasen N, Marcusson J, Blennow K (2004) APOE epsilon4 allele is associated with reduced cerebrospinal fluid levels of AbetaNeurology 62, 2116-2118.
    • (2004) Neurology , vol.62 , pp. 2116-2118
    • Prince, J.A.1    Zetterberg, H.2    Andreasen, N.3    Marcusson, J.4    Blennow, K.5
  • 18
    • 0016823810 scopus 로고
    • "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR (1975) "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. JPsychiatr Res 12, 189-198.
    • (1975) JPsychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 19
    • 0021271971 scopus 로고
    • Clinical diagnosis ofAlzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis ofAlzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 23
  • 27
    • 0036233168 scopus 로고    scopus 로고
    • Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease
    • Fagan AM, Watson M, Parsadanian M, Bales KR, Paul SM, Holtzman DM (2002) Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease. Neurobiol Dis 9, 305-318.
    • (2002) Neurobiol Dis , vol.9 , pp. 305-318
    • Fagan, A.M.1    Watson, M.2    Parsadanian, M.3    Bales, K.R.4    Paul, S.M.5    Holtzman, D.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.