Parkin reverses intracellular β-amyloid accumulation and its negative effects on proteasome function

Journal of Neuroscience Research

Volumn 88, Issue 1, 2010, Pages 167-178

  Rosen, Kenneth M ^a   Moussa, Charbel E H ^a   Lee, Han Kyu ^a   Kumar, Pravir ^a   Kitada, Tohru ^b   Qin, Gangjian ^a   Fu, Qinghao ^a   Querfurth, Henry W ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Alzheimer's; Amyloid; Parkin; Proteasome; Ubiquitin ligase

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; MEMBRANE METALLOENDOPEPTIDASE; PARKIN; PROTEASOME; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; UBIQUITIN PROTEIN LIGASE E3;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BRAIN; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCOMPETENT CELL; MOUSE; NERVE CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STEADY STATE; WILD TYPE;

ADENOSINE TRIPHOSPHATE; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; CYTOPROTECTION; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOPRECIPITATION; MICE; MICE, TRANSGENIC; MUTATION; NEURONS; PEPTIDE FRAGMENTS; PROTEASOME ENDOPEPTIDASE COMPLEX; TRANSFECTION; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 73949083524     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22178     Document Type: Article

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