Seeding plaques in Alzheimer's disease

Journal of Neurochemistry

Volumn 120, Issue 5, 2012, Pages 641-643

  Prado, Marco A M ^a   Baron, Gerald ^b  

^a WESTERN UNIVERSITY   (Canada)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BRAIN EXTRACT; PRION PROTEIN; TAU PROTEIN;

ALZHEIMER DISEASE; AMYLOID PLAQUE; BRAIN FUNCTION; CAUSAL ATTRIBUTION; DISEASE ASSOCIATION; DOWN SYNDROME; ELECTROENCEPHALOGRAM; EXPERIMENTAL MOUSE; HUMAN; MEMBRANE STEADY POTENTIAL; NEUROPATHOLOGY; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; REVIEW; SYNAPTIC POTENTIAL; UPREGULATION;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CEREBRAL AMYLOID ANGIOPATHY; HUMANS; NEOCORTEX;

EID: 84857157206     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07574.x     Document Type: Review

References (18)

1. Agca C., Fritz J. J., Walker L. C., Levey A. I., Chan A. W., Lah J. J., and, Agca Y., (2008) Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically. BMC Neurosci. 9, 28.
2. Bero A. W., Yan P., Roh J. H., Cirrito J. R., Stewart F. R., Raichle M. E., Lee J. M., and, Holtzman D. M., (2011) Neuronal activity regulates the regional vulnerability to amyloid-beta deposition. Nat. Neurosci. 14, 750-756.
3. Choi J. H., Berger J. D., Mazzella M. J., Morales-Corraliza J., Cataldo A. M., Nixon R. A., Ginsberg S. D., Levy E., and, Mathews P. M., (2009) Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model. J. Neurochem. 110, 1818-1827.
4. Eisele Y. S., Bolmont T., Heikenwalder M., et al. (2009) Induction of cerebral beta-amyloidosis: intracerebral versus systemic Abeta inoculation. Proc. Natl. Acad. Sci. USA 106, 12926-12931.
5. Eisele Y. S., Obermuller U., Heilbronner G., Baumann F., Kaeser S. A., Wolburg H., Walker L. C., Staufenbiel M., Heikenwalder M., and, Jucker M., (2010) Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis. Science 330, 980-982.
6. Klingeborn M., Race B., Meade-White K. D., Rosenke R., Striebel J. F., and, Chesebro B., (2011) Crucial role for prion protein membrane anchoring in the neuroinvasion and neural spread of prion infection. J. Virol. 85, 1484-1494.
7. Langer F., Eisele Y. S., Fritschi S. K., Staufenbiel M., Walker L. C., and, Jucker M., (2011) Soluble A{beta} seeds are potent inducers of cerebral {beta}-amyloid deposition. J. Neurosci. 31, 14488-14495.
8. Meyer-Luehmann M., Coomaraswamy J., Bolmont T., et al. (2006) Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science 313, 1781-1784.
9. Morales R., Duran-Aniotz C., Castilla J., Estrada L. D., and, Soto C., (2011) De novo induction of amyloid-beta deposition in vivo. Mol. Psychiatry (in press).
10. Mucke L., Masliah E., Yu G. Q., Mallory M., Rockenstein E. M., Tatsuno G., Hu K., Kholodenko D., Johnson-Wood K., and, McConlogue L., (2000) High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation. J. Neurosci. 20, 4050-4058.
11. Ono K., and, Yamada M., (2011) Low-n oligomers as therapeutic targets of Alzheimer's disease. J. Neurochem. 117, 19-28.
12. Rosen F. R., Fritz J. J., Dooyema J., Cintron A. F., Hamaguchi T., Lah J. J., LeVine H., III, Jucker M., and, Walker L. C., (2011) Exogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats. J. Neurochem. 120, 660-666.
13. Selkoe D. J., (2011) Resolving controversies on the path to Alzheimer's therapeutics. Nat. Med. 17, 1060-1065.
14. Silveira J. R., Raymond G. J., Hughson A. G., Race R. E., Sim V. L., Hayes S. F., and, Caughey B., (2005) The most infectious prion protein particles. Nature 437, 257-261.
15. Speare J. O., Offerdahl D. K., Hasenkrug A., Carmody A. B., and, Baron G. S., (2010) GPI anchoring facilitates propagation and spread of misfolded Sup35 aggregates in mammalian cells. EMBO J. 29, 782-794.
16. Sperling R. A., Laviolette P. S., O'Keefe K., et al. (2009) Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron 63, 178-188.
17. Walker L. C., Levine III H., Mattson M. P., and, Jucker M., (2006) Inducible proteopathies. Trends Neurosci. 29, 438-443.
18. Wiseman F. K., Alford K. A., Tybulewicz V. L., and, Fisher E. M., (2009) Down syndrome-recent progress and future prospects. Hum. Mol. Genet. 18, R75-R83.