The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves huntingtin phosphorylation by Akt

Developmental Cell

Volumn 2, Issue 6, 2002, Pages 831-837

  Humbert, Sandrine ^a   Bryson, Elzbieta A ^a   Cordelières, Fabrice P ^a   Connors, Nathan C ^b   Datta, Sandeep R ^b   Finkbeiner, Steven ^c   Greenberg, Michael E ^b   Saudou, Frédéric ^a  

^a INSTITUT CURIE   (France)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUNTINGTIN; MUTANT PROTEIN; POLYGLUTAMINE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; SOMATOMEDIN C;

ARTICLE; CELL DEATH; CELL NUCLEUS INCLUSION BODY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME SUBSTRATE; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; NERVE CELL; NEUROPROTECTION; PROTEIN PHOSPHORYLATION;

EID: 0036083379     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1534-5807(02)00188-0     Document Type: Article

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