The accumulation of neurotoxic proteins, induced by proteasome inhibition, is reverted by trehalose, an enhancer of autophagy, in human neuroblastoma cells

Neurochemistry International

Volumn 58, Issue 4, 2011, Pages 512-520

  Casarejos, M J ^a   Solano, R M ^a   Gomez A ^a   Perucho, J ^a   De Yebenes J G ^a   Mena, M A ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

Synuclein; Autophagy lysosomal pathway; Chaperones; DJ 1; Glutathione; p Tau; Parkinson's disease; Proteasome activity; Tau; Ubiquitination

Indexed keywords

ALPHA SYNUCLEIN; CHAPERONE; DISACCHARIDE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPOXOMICIN; FREE RADICAL; GLUTATHIONE; HEAT SHOCK PROTEIN 70; MITOCHONDRIAL PROTEIN; POL PROTEIN; POLYUBIQUITIN; PROTEASOME; PROTEIN; SCAVENGER; SYNUCLEIN; TAU PROTEIN; TREHALOSE; UBIQUITIN;

ARTICLE; AUTOPHAGY; CELL DEATH; CORRELATION ANALYSIS; DEGENERATIVE DISEASE; ENHANCER REGION; ENVIRONMENTAL STRESS; ENZYME INHIBITION; HUMAN; NECROSIS; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION;

AUTOPHAGY; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ENZYME INHIBITORS; HUMANS; IMMUNOHISTOCHEMISTRY; NEUROBLASTOMA; OLIGOPEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEINS; TREHALOSE;

MAMMALIA;

EID: 79952104480     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.01.008     Document Type: Article

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