메뉴 건너뛰기




Volumn 32, Issue 2, 2012, Pages 357-372

Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly

Author keywords

Cognitive function; dementia; DNA sequencing; mitochondria; mtDNA; oxidative phosphorylation

Indexed keywords

MITOCHONDRIAL DNA;

EID: 84867516927     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2012-120466     Document Type: Article
Times cited : (37)

References (172)
  • 1
    • 0042023711 scopus 로고    scopus 로고
    • Alzheimer disease in the US population: Prevalence estimates using the 2000 census
    • Hebert LE, Scherr PA, Bienias JL, Bennett DA, Evans DA (2003) Alzheimer disease in the US population: Prevalence estimates using the 2000 census. Arch Neurol 60, 1119- 1122.
    • (2003) Arch Neurol , vol.60 , pp. 1119-1122
    • Hebert, L.E.1    Scherr, P.A.2    Bienias, J.L.3    Bennett, D.A.4    Evans, D.A.5
  • 2
    • 77950229880 scopus 로고    scopus 로고
    • Neural mechanisms of ageing and cognitive decline
    • Bishop NA, Lu T, Yankner BA (2010) Neural mechanisms of ageing and cognitive decline. Nature 464, 529-535.
    • (2010) Nature , vol.464 , pp. 529-535
    • Bishop, N.A.1    Lu, T.2    Yankner, B.A.3
  • 3
    • 77956206298 scopus 로고    scopus 로고
    • Amitocentric viewof Alzheimer's disease suggests multi-faceted treatments
    • Gibson GE, ShiQ(2010)Amitocentric viewof Alzheimer's disease suggests multi-faceted treatments. J Alzheimers Dis 20(SUPPL2 S591-S607
    • (2010) J Alzheimers Dis , vol.20 , Issue.SUPPL. 2
    • Gibson, G.E.1    Shi, Q.2
  • 7
    • 0036284936 scopus 로고    scopus 로고
    • Increase of brain oxidative stress in mild cognitive impairment: A possible predictor of Alzheimer disease
    • Pratico D, Clark CM, Liun F, Rokach J, Lee VY, Trojanowski JQ (2002) Increase of brain oxidative stress in mild cognitive impairment: A possible predictor of Alzheimer disease. Arch Neurol 59, 972-976.
    • (2002) Arch Neurol , vol.59 , pp. 972-976
    • Pratico, D.1    Clark, C.M.2    Liun, F.3    Rokach, J.4    Lee, V.Y.5    Trojanowski, J.Q.6
  • 8
    • 0035985698 scopus 로고    scopus 로고
    • Lipid peroxidation in neurodegeneration: New insights into alzheimer's disease
    • Arlt S, Beisiegel U, Kontush A (2002) Lipid peroxidation in neurodegeneration: New insights into Alzheimer's disease. urr Opin Lipidol 13, 289-294.
    • (2002) Urr Opin Lipidol , vol.13 , pp. 289-294
    • Arlt, S.1    Beisiegel, U.2    Kontush, A.3
  • 9
    • 0028908516 scopus 로고
    • Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons
    • Harris ME, Hensley K, Butterfield DA, Leedle RA, Carney JM(1995) Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons. Exp Neurol 131, 193-202.
    • (1995) Exp Neurol , vol.131 , pp. 193-202
    • Harris, M.E.1    Hensley, K.2    Butterfield, D.A.3    Leedle, R.A.4    Carney, J.M.5
  • 10
    • 0033969616 scopus 로고    scopus 로고
    • Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease brain
    • Lovell MA, Xie C, Gabbita SP, Markesbery WR (2000) Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease brain. Free Radic Biol Med 28, 418-427.
    • (2000) Free Radic Biol Med , vol.28 , pp. 418-427
    • Lovell, M.A.1    Xie, C.2    Gabbita, S.P.3    Markesbery, W.R.4
  • 11
    • 1342306400 scopus 로고    scopus 로고
    • Acrolein inhibits NADH-linked mitochondrial enzyme activity: Implications for Alzheimer's disease
    • Pocernich CB, Butterfield DA (2003) Acrolein inhibits NADH-linked mitochondrial enzyme activity: Implications for Alzheimer's disease. Neurotox Res 5, 515-520.
    • (2003) Neurotox Res , vol.5 , pp. 515-520
    • Pocernich, C.B.1    Butterfield, D.A.2
  • 13
    • 0033000269 scopus 로고    scopus 로고
    • Depolarization of in situ mitochondria due to hydrogen peroxide-induced oxidative stress in nerve terminals: Inhibition of alpha-ketoglutarate dehydrogenase
    • Chinopoulos C, Tretter L, Adam-Vizi V (1999) Depolarization of in situ mitochondria due to hydrogen peroxide-induced oxidative stress in nerve terminals: Inhibition of alpha-ketoglutarate dehydrogenase. J Neurochem 73, 220-228.
    • (1999) J Neurochem , vol.73 , pp. 220-228
    • Chinopoulos, C.1    Tretter, L.2    Adam-Vizi, V.3
  • 14
    • 0033048258 scopus 로고    scopus 로고
    • Metabolic impairment induces oxidative stress, compromises inflammatory responses, and inactivates a key mitochondrial enzyme in microglia
    • Park LC, Zhang H, Sheu KF, Calingasan NY, Kristal BS, Lindsay JG, Gibson GE (1999) Metabolic impairment induces oxidative stress, compromises inflammatory responses, and inactivates a key mitochondrial enzyme in microglia. J Neurochem 72, 1948-1958.
    • (1999) J Neurochem , vol.72 , pp. 1948-1958
    • Park, L.C.1    Zhang, H.2    Sheu, K.F.3    Calingasan, N.Y.4    Kristal, B.S.5    Lindsay, J.G.6    Gibson, G.E.7
  • 15
    • 0034670134 scopus 로고    scopus 로고
    • Differential alterations in antioxidant capacity in cells from Alzheimer patients
    • Gibson GE, Zhang H, Sheu KR, Park LC (2000) Differential alterations in antioxidant capacity in cells from Alzheimer patients. Biochim Biophys Acta 1502, 319-329.
    • (2000) Biochim Biophys Acta , vol.1502 , pp. 319-329
    • Gibson, G.E.1    Zhang, H.2    Sheu, K.R.3    Park, L.C.4
  • 16
    • 0345146921 scopus 로고    scopus 로고
    • Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status
    • Nulton-Persson AC, Starke DW, Mieyal JJ, Szweda LI (2003) Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status. Biochemistry 42, 4235- 4242.
    • (2003) Biochemistry , vol.42 , pp. 4235-4242
    • Nulton-Persson, A.C.1    Starke, D.W.2    Mieyal, J.J.3    Szweda, L.I.4
  • 17
    • 0032506040 scopus 로고    scopus 로고
    • Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: Reaction of lipoic acid with 4-hydroxy-2-nonenal
    • Humphries KM, Szweda LI (1998) Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: Reaction of lipoic acid with 4-hydroxy-2-nonenal. Biochemistry 37, 15835-15841.
    • (1998) Biochemistry , vol.37 , pp. 15835-15841
    • Humphries, K.M.1    Szweda, L.I.2
  • 18
    • 0023116918 scopus 로고
    • Inactivation of 2- oxoglutarate dehydrogenase in rat liver mitochondria by its substrate and t-butyl hydroperoxide
    • Rokutan K, Kawai K, Asada K (1987) Inactivation of 2- oxoglutarate dehydrogenase in rat liver mitochondria by its substrate and t-butyl hydroperoxide. J Biochem 101, 415- 422.
    • (1987) J Biochem , vol.101 , pp. 415-422
    • Rokutan, K.1    Kawai, K.2    Asada, K.3
  • 19
    • 0029995035 scopus 로고    scopus 로고
    • Catecholamines enhance dihydrolipoamide dehydrogenase inactivation by the copper Fenton system. Enzyme protection by copper chelators
    • Correa JG, Stoppani AO (1996) Catecholamines enhance dihydrolipoamide dehydrogenase inactivation by the copper Fenton system. Enzyme protection by copper chelators. Free Radic Res 24, 311-322.
    • (1996) Free Radic Res , vol.24 , pp. 311-322
    • Correa, J.G.1    Stoppani, A.O.2
  • 20
    • 0942298545 scopus 로고    scopus 로고
    • Endogenous mitochondrial oxidative stress: Neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice
    • Hinerfeld D, Traini MD, Weinberger RP, Cochran B, Doctrow SR, Harry J, Melov S (2004) Endogenous mitochondrial oxidative stress: Neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice. J Neurochem 88, 657-667.
    • (2004) J Neurochem , vol.88 , pp. 657-667
    • Hinerfeld, D.1    Traini, M.D.2    Weinberger, R.P.3    Cochran, B.4    Doctrow, S.R.5    Harry, J.6    Melov, S.7
  • 21
    • 0027059235 scopus 로고
    • Inactivation of mitochondrial metabolism by hyperoxia-induced oxidative stress
    • Pruijn FB, Schoonen WG, Joenje H (1992) Inactivation of mitochondrial metabolism by hyperoxia-induced oxidative stress. Ann N Y Acad Sci 663, 453-455.
    • (1992) Ann N y Acad Sci , vol.663 , pp. 453-455
    • Pruijn, F.B.1    Schoonen, W.G.2    Joenje, H.3
  • 22
    • 0026073545 scopus 로고
    • Characterization of oxygenresistant Chinese hamster ovary cells III relative resistance of succinate and alpha-ketoglutarate dehydrogenases to hyperoxic inactivation
    • Schoonen WG, Wanamarta AH, van der Klei-van Moorsel JM, Jakobs C, Joenje H (1991) Characterization of oxygenresistant Chinese hamster ovary cells. III. Relative resistance of succinate and alpha-ketoglutarate dehydrogenases to hyperoxic inactivation. Free Radic Biol Med 10, 111-118.
    • (1991) Free Radic Biol Med , vol.10 , pp. 111-118
    • Schoonen, W.G.1    Wanamarta, A.H.2    Vanderklei-Vanmoorsel, J.M.3    Jakobs, C.4    Joenje, H.5
  • 23
    • 40849133924 scopus 로고    scopus 로고
    • Novel functions of the alpha-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease
    • Shi Q, Xu H, KleinmanWA, Gibson GE (2008) Novel functions of the alpha-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease. Biochim Biophys Acta 1782, 229-238.
    • (2008) Biochim Biophys Acta , vol.1782 , pp. 229-238
    • Shi, Q.1    Xu, H.2    Kleinman, W.A.3    Gibson, G.E.4
  • 24
    • 0028200649 scopus 로고
    • Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative
    • Gabuzda D, Busciglio J, Chen LB, Matsudaira P, Yankner BA (1994) Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative. J Biol Chem 269, 13623-13628.
    • (1994) J Biol Chem , vol.269 , pp. 13623-13628
    • Gabuzda, D.1    Busciglio, J.2    Chen, L.B.3    Matsudaira, P.4    Yankner, B.A.5
  • 29
    • 0032905632 scopus 로고    scopus 로고
    • Protein-bound acrolein: A novel marker of oxidative stress in Alzheimer's disease
    • CalingasanNY, Uchida K, GibsonGE(1999) Protein-bound acrolein: A novel marker of oxidative stress in Alzheimer's disease. J Neurochem 72, 751-756.
    • (1999) J Neurochem , vol.72 , pp. 751-756
    • Calingasan, N.Y.1    Uchida, K.2    Gibson, G.E.3
  • 31
    • 70149093436 scopus 로고    scopus 로고
    • Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
    • Yao J, Irwin RW, Zhao L, Nilsen J, Hamilton RT, Brinton RD (2009) Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 106, 14670- 14675.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 14670-14675
    • Yao, J.1    Irwin, R.W.2    Zhao, L.3    Nilsen, J.4    Hamilton, R.T.5    Brinton, R.D.6
  • 33
    • 33646152108 scopus 로고    scopus 로고
    • Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: Implications for free radical generation and oxidative damage in disease progression
    • Manczak M, Anekonda TS, Henson E, Park BS, Quinn J, Reddy PH (2006) Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: Implications for free radical generation and oxidative damage in disease progression. Hum Mol Genet 15, 1437-1449.
    • (2006) Hum Mol Genet , vol.15 , pp. 1437-1449
    • Manczak, M.1    Anekonda, T.S.2    Henson, E.3    Park, B.S.4    Quinn, J.5    Reddy, P.H.6
  • 35
    • 0035875690 scopus 로고    scopus 로고
    • Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis
    • Pratico D, Uryu K, Leight S, Trojanoswki JQ, Lee VM (2001) Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. J Neurosci 21, 4183-4187.
    • (2001) J Neurosci , vol.21 , pp. 4183-4187
    • Pratico, D.1    Uryu, K.2    Leight, S.3    Trojanoswki, J.Q.4    Lee, V.M.5
  • 37
    • 0033903441 scopus 로고    scopus 로고
    • Mitochondrial DNA damage as a mechanism of cell loss in Alzheimer's disease
    • de la Monte SM, Luong T, Neely TR, Robinson D, Wands JR (2000) Mitochondrial DNA damage as a mechanism of cell loss in Alzheimer's disease. Lab Invest 80, 1323-1335.
    • (2000) Lab Invest , vol.80 , pp. 1323-1335
    • De La Monte, S.M.1    Luong, T.2    Neely, T.R.3    Robinson, D.4    Wands, J.R.5
  • 38
    • 0030738721 scopus 로고    scopus 로고
    • Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging
    • Anglade P, Vyas S, Hirsch EC, Agid Y (1997) Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging. Histol Histopathol 12, 603-610.
    • (1997) Histol Histopathol , vol.12 , pp. 603-610
    • Anglade, P.1    Vyas, S.2    Hirsch, E.C.3    Agid, Y.4
  • 39
    • 77956197971 scopus 로고    scopus 로고
    • Mitochondrial amyloid-beta levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's transgenic mice
    • Dragicevic N, Mamcarz M, Zhu Y, Buzzeo R, Tan J, ArendashGW, BradshawPC (2010) Mitochondrial amyloid-beta levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's transgenic mice. J Alzheimers Dis 20(SUPPL2 S535-S550.
    • (2010) J Alzheimers Dis , vol.20 , Issue.SUPPL. 2
    • Dragicevic, N.1    Mamcarz, M.2    Zhu, Y.3    Buzzeo, R.4    Tan, J.5    Arendash, G.W.6    Bradshaw, P.C.7
  • 40
    • 0031081410 scopus 로고    scopus 로고
    • A proposed refinement of the mitochondrial free radical theory of aging
    • de Grey AD (1997) A proposed refinement of the mitochondrial free radical theory of aging. Bioessays 19, 161-166.
    • (1997) Bioessays , vol.19 , pp. 161-166
    • De Grey, A.D.1
  • 41
    • 10244255083 scopus 로고    scopus 로고
    • Mitochondrial enzymes and endoplasmic reticulum calcium stores as targets of oxidative stress in neurodegenerative diseases
    • Gibson GE, Huang HM (2004) Mitochondrial enzymes and endoplasmic reticulum calcium stores as targets of oxidative stress in neurodegenerative diseases. J Bioenerg Biomembr 36, 335-340.
    • (2004) J Bioenerg Biomembr , vol.36 , pp. 335-340
    • Gibson, G.E.1    Huang, H.M.2
  • 42
    • 70449670310 scopus 로고    scopus 로고
    • Selective vulnerability of brain regions to oxidative stress in a non-coma model of insulin-induced hypoglycemia
    • Haces ML, Montiel T, Massieu L (2010) Selective vulnerability of brain regions to oxidative stress in a non-coma model of insulin-induced hypoglycemia. Neuroscience 165, 28-38.
    • (2010) Neuroscience , vol.165 , pp. 28-38
    • Haces, M.L.1    Montiel, T.2    Massieu, L.3
  • 44
    • 0036592758 scopus 로고    scopus 로고
    • The role of the metabolic lesion in Alzheimer's disease
    • Blass JP, Gibson GE, Hoyer S (2002) The role of the metabolic lesion in Alzheimer's disease. J Alzheimers Dis 4, 225-232.
    • (2002) J Alzheimers Dis , vol.4 , pp. 225-232
    • Blass, J.P.1    Gibson, G.E.2    Hoyer, S.3
  • 48
    • 77952415166 scopus 로고    scopus 로고
    • Colloquium paper: Bioenergetics, the origins of complexity, and the ascent of man
    • Wallace DC (2010) Colloquium paper: Bioenergetics, the origins of complexity, and the ascent of man. Proc Natl Acad Sci U S A 107(SUPPL2 8947-8953.
    • (2010) Proc Natl Acad Sci U S -Rfaut , vol.107 , Issue.SUPPL. 2 , pp. 8947-8953
    • Wallace, D.C.1
  • 49
    • 0028286006 scopus 로고
    • Molecular basis of mitochondrial DNA disease
    • Brown MD, Wallace DC (1994) Molecular basis of mitochondrial DNA disease. J Bioenerg Biomembr 26, 273-289.
    • (1994) J Bioenerg Biomembr , vol.26 , pp. 273-289
    • Brown, M.D.1    Wallace, D.C.2
  • 50
    • 0027311861 scopus 로고
    • The expanding clinical spectrum of mitochondrial diseases
    • De Vivo DC (1993) The expanding clinical spectrum of mitochondrial diseases. Brain Dev 15, 1-22.
    • (1993) Brain Dev , vol.15 , pp. 1-22
    • De Vivo, D.C.1
  • 52
    • 0035234813 scopus 로고    scopus 로고
    • A mitochondrial paradigm for degenerative diseases and ageing
    • discussion 263-246
    • Wallace DC (2001) A mitochondrial paradigm for degenerative diseases and ageing. Novartis Found Symp 235, 247-263; discussion 263-246.
    • (2001) Novartis Found Symp , vol.235 , pp. 247-263
    • Wallace, D.C.1
  • 54
    • 2342628596 scopus 로고    scopus 로고
    • Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: Implications for early mitochondrial dysfunction and oxidative damage
    • Manczak M, Park BS, JungY, Reddy PH (2004) Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: Implications for early mitochondrial dysfunction and oxidative damage. Neuromolecular Med 5, 147-162.
    • (2004) Neuromolecular Med , vol.5 , pp. 147-162
    • Manczak, M.1    Park, B.S.2    Jung, Y.3    Reddy, P.H.4
  • 56
    • 0029864498 scopus 로고    scopus 로고
    • Human brain contains high levels of heteroplasmy in the noncoding regions of mitochondrial DNA
    • Jazin EE, Cavelier L, Eriksson I, Oreland L, Gyllensten U (1996) Human brain contains high levels of heteroplasmy in the noncoding regions of mitochondrial DNA. Proc Natl Acad Sci U S A 93, 12382-12387.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 12382-12387
    • Jazin, E.E.1    Cavelier, L.2    Eriksson, I.3    Oreland, L.4    Gyllensten, U.5
  • 57
    • 0026782895 scopus 로고
    • Deleterious mitochondrial DNA mutations accumulate in aging human tissues
    • Arnheim N, Cortopassi G (1992) Deleterious mitochondrial DNA mutations accumulate in aging human tissues. Mutat Res 275, 157-167.
    • (1992) Mutat Res , vol.275 , pp. 157-167
    • Arnheim, N.1    Cortopassi, G.2
  • 60
    • 33646351299 scopus 로고    scopus 로고
    • Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
    • KraytsbergY,Kudryavtseva E,McKeeAC, Geula C,Kowall NW, Khrapko K (2006) Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat Genet 38, 518-520.
    • (2006) Nat Genet , vol.38 , pp. 518-520
    • Kraytsberg, Y.1    Kudryavtseva, E.2    McKee, A.C.3    Geula, C.4    Kowall, N.W.5    Khrapko, K.6
  • 62
    • 0027021442 scopus 로고
    • Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain
    • Soong NW, Hinton DR, Cortopassi G, Arnheim N (1992) Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain. Nat Genet 2, 318-323.
    • (1992) Nat Genet , vol.2 , pp. 318-323
    • Soong, N.W.1    Hinton, D.R.2    Cortopassi, G.3    Arnheim, N.4
  • 65
    • 77952541558 scopus 로고    scopus 로고
    • The sites and topology of mitochondrial superoxide production
    • Brand MD (2010) The sites and topology of mitochondrial superoxide production. Exp Gerontol 45, 466-472.
    • (2010) Exp Gerontol , vol.45 , pp. 466-472
    • Brand, M.D.1
  • 66
    • 0037424245 scopus 로고    scopus 로고
    • Mitochondrial complex i inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production
    • Li N, Ragheb K, Lawler G, Sturgis J, Rajwa B, Melendez JA, Robinson JP (2003) Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J Biol Chem 278, 8516-8525.
    • (2003) J Biol Chem , vol.278 , pp. 8516-8525
    • Li, N.1    Ragheb, K.2    Lawler, G.3    Sturgis, J.4    Rajwa, B.5    Melendez, J.A.6    Robinson, J.P.7
  • 67
    • 1842425028 scopus 로고    scopus 로고
    • Attenuation of free radical production and paracrystalline inclusions by creatine supplementation in a patient with a novel cytochrome b mutation
    • Tarnopolsky MA, Simon DK, Roy BD, Chorneyko K, Lowther SA, Johns DR, Sandhu JK, LiY, SikorskaM(2004) Attenuation of free radical production and paracrystalline inclusions by creatine supplementation in a patient with a novel cytochrome b mutation. Muscle Nerve 29, 537-547.
    • (2004) Muscle Nerve , vol.29 , pp. 537-547
    • Tarnopolsky, M.A.1    Simon, D.K.2    Roy, B.D.3    Chorneyko, K.4    Lowther, S.A.5    Johns, D.R.6    Sandhu, J.K.7    Li, Y.8    Sikorska, M.9
  • 69
    • 0030294728 scopus 로고    scopus 로고
    • Cytochrome c oxidase defects of the human substantia nigra in normal aging
    • Itoh K, Weis S, Mehraein P, Muller-Hocker J (1996) Cytochrome c oxidase defects of the human substantia nigra in normal aging. Neurobiol Aging 17, 843-848.
    • (1996) Neurobiol Aging , vol.17 , pp. 843-848
    • Itoh, K.1    Weis, S.2    Mehraein, P.3    Muller-Hocker, J.4
  • 72
    • 0029091194 scopus 로고
    • AmitochondrialDNAclone is associated with increased risk for Alzheimer disease
    • Hutchin T, CortopassiG(1995)AmitochondrialDNAclone is associated with increased risk for Alzheimer disease. Proc Natl Acad Sci U S A 92, 6892-6895.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 6892-6895
    • Hutchin, T.1    Cortopassi, G.2
  • 74
    • 0030016323 scopus 로고    scopus 로고
    • Increased risk of dementia in mothers of Alzheimer's disease cases: Evidence for maternal inheritance
    • Edland SD, Silverman JM, Peskind ER, Tsuang D,Wijsman E, Morris JC (1996) Increased risk of dementia in mothers of Alzheimer's disease cases: Evidence for maternal inheritance. Neurology 47, 254-256.
    • (1996) Neurology , vol.47 , pp. 254-256
    • Edland, S.D.1    Silverman, J.M.2    Peskind, E.R.3    Tsuang, D.4    Wijsman, E.5    Morris, J.C.6
  • 76
    • 0035793961 scopus 로고    scopus 로고
    • Two point mutations in mitochondrial DNA of cytochrome c oxidase coexist with normal mtDNA in a patient with Alzheimer's disease
    • Qiu X, Chen Y, Zhou M (2001) Two point mutations in mitochondrial DNA of cytochrome c oxidase coexist with normal mtDNA in a patient with Alzheimer's disease. Brain Res 893, 261-263.
    • (2001) Brain Res , vol.893 , pp. 261-263
    • Qiu, X.1    Chen, Y.2    Zhou, M.3
  • 77
    • 0031977710 scopus 로고    scopus 로고
    • MtDNA polymorphisms in Japanese sporadic Alzheimer's disease
    • Tanno Y, Okuizumi K, Tsuji S (1998) mtDNA polymorphisms in Japanese sporadic Alzheimer's disease. Neurobiol Aging 19, S47-S51.
    • (1998) Neurobiol Aging , vol.19
    • Tanno, Y.1    Okuizumi, K.2    Tsuji, S.3
  • 80
    • 0027935035 scopus 로고
    • No association of mutations at nucleotide 5460 of mitochondrial NADH dehydrogenase with Alzheimer's disease
    • Kosel S, Egensperger R, Mehraein P, GraeberMB(1994) No association of mutations at nucleotide 5460 of mitochondrial NADH dehydrogenase with Alzheimer's disease. Biochem Biophys Res Commun 203, 745-749.
    • (1994) Biochem Biophys Res Commun , vol.203 , pp. 745-749
    • Kosel, S.1    Egensperger, R.2    Mehraein, P.3    Graeber, M.B.4
  • 81
    • 0026672905 scopus 로고
    • Is a point mutation in the mitochondrial ND2 gene associated withAlzheimer's disease
    • Petruzzella V, Chen X, Schon EA (1992) Is a point mutation in the mitochondrial ND2 gene associated withAlzheimer's disease. Biochem Biophys Res Commun 186, 491-497.
    • (1992) Biochem Biophys Res Commun , vol.186 , pp. 491-497
    • Petruzzella, V.1    Chen, X.2    Schon, E.A.3
  • 82
    • 0028843809 scopus 로고
    • No association found between Alzheimer's disease and a mitochondrial tRNA glutamine gene variant
    • Wragg MA, Talbot CJ, Morris JC, Lendon CL, Goate AM (1995) No association found between Alzheimer's disease and a mitochondrial tRNA glutamine gene variant. Neurosci Lett 201, 107-110.
    • (1995) Neurosci Lett , vol.201 , pp. 107-110
    • Wragg, M.A.1    Talbot, C.J.2    Morris, J.C.3    Lendon, C.L.4    Goate, A.M.5
  • 83
    • 0030299996 scopus 로고    scopus 로고
    • The tRNA(Gln) 4336 mitochondrial DNA variant is not a high penetrance mutation which predisposes to dementia before the age of 75 years
    • Tysoe C, Robinson D, Brayne C, Dening T, Paykel ES, Huppert FA, Rubinsztein DC (1996) The tRNA(Gln) 4336 mitochondrial DNA variant is not a high penetrance mutation which predisposes to dementia before the age of 75 years. J Med Genet 33, 1002-1006.
    • (1996) J Med Genet , vol.33 , pp. 1002-1006
    • Tysoe, C.1    Robinson, D.2    Brayne, C.3    Dening, T.4    Paykel, E.S.5    Huppert, F.A.6    Rubinsztein, D.C.7
  • 84
    • 0029965659 scopus 로고    scopus 로고
    • Investigations on the point mutations at nt 5460 of the mtDNA in different neurodegenerative and neuromuscular diseases
    • JanetzkyB, Schmid C, Bischof F, Frolich L, GsellW, Kalaria RN, Riederer P, Reichmann H (1996) Investigations on the point mutations at nt 5460 of the mtDNA in different neurodegenerative and neuromuscular diseases. Eur Neurol 36, 149-153.
    • (1996) Eur Neurol , vol.36 , pp. 149-153
    • Janetzky, B.1    Schmid, C.2    Bischof, F.3    Frolich, L.4    Gsell, W.5    Kalaria, R.N.6    Riederer, P.7    Reichmann, H.8
  • 85
    • 0031464288 scopus 로고    scopus 로고
    • Ancient mtDNA sequences in the human nuclear genome: A potential source of errors in identifying pathogenic mutations
    • Wallace DC, Stugard C, Murdock D, Schurr T, Brown MD (1997) Ancient mtDNA sequences in the human nuclear genome: A potential source of errors in identifying pathogenic mutations. Proc Natl Acad Sci U S A 94, 14900-14905.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 14900-14905
    • Wallace, D.C.1    Stugard, C.2    Murdock, D.3    Schurr, T.4    Brown, M.D.5
  • 86
    • 0023449963 scopus 로고
    • Cdna sequence of a human skeletal muscle ADP/ATP translocator: Lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes
    • Neckelmann N, Li K, Wade RP, Shuster R, Wallace DC (1987) cDNA sequence of a human skeletal muscle ADP/ATP translocator: Lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes. Proc Natl Acad Sci U S A 84, 7580-7584.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 7580-7584
    • Neckelmann, N.1    Li, K.2    Wade, R.P.3    Shuster, R.4    Wallace, D.C.5
  • 88
  • 89
    • 0036303035 scopus 로고    scopus 로고
    • The association of race and socioeconomic status with cardiovascular disease indicators among older adults in the health, aging, and body composition study
    • Rooks RN, Simonsick EM, Miles T, Newman A, Kritchevsky SB, Schulz R, Harris T (2002) The association of race and socioeconomic status with cardiovascular disease indicators among older adults in the health, aging, and body composition study. J Gerontol B Psychol Sci Soc Sci 57, S247-S256.
    • (2002) J Gerontol B Psychol Sci Soc Sci , vol.57
    • Rooks, R.N.1    Simonsick, E.M.2    Miles, T.3    Newman, A.4    Kritchevsky, S.B.5    Schulz, R.6    Harris, T.7
  • 90
    • 0023194048 scopus 로고
    • The Modified Mini-Mental State (3MS) examination
    • Teng EL, Chui HC (1987) The Modified Mini-Mental State (3MS) examination. J Clin Psychiatry 48, 314-318.
    • (1987) J Clin Psychiatry , vol.48 , pp. 314-318
    • Teng, E.L.1    Chui, H.C.2
  • 92
    • 0019451926 scopus 로고
    • Improved digit symbol substitution by older women as a result of extended practice
    • Beres CA, Baron A (1981) Improved digit symbol substitution by older women as a result of extended practice. J Gerontol 36, 591-597.
    • (1981) J Gerontol , vol.36 , pp. 591-597
    • Beres, C.A.1    Baron, A.2
  • 93
    • 0023269040 scopus 로고
    • Psychometric differentiation of dementia. Replication and extension of the findings of Storandt and coworkers
    • Tierney MC, SnowWG, Reid DW, Zorzitto ML, Fisher RH (1987) Psychometric differentiation of dementia. Replication and extension of the findings of Storandt and coworkers. Arch Neurol 44, 720-722.
    • (1987) Arch Neurol , vol.44 , pp. 720-722
    • Tierney, M.C.1    Snow, W.G.2    Reid, D.W.3    Zorzitto, M.L.4    Fisher, R.H.5
  • 97
    • 64049089255 scopus 로고    scopus 로고
    • Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation
    • van Oven M, Kayser M (2009) Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Hum Mutat 30, E386-E394.
    • (2009) Hum Mutat , vol.30
    • Van Oven, M.1    Kayser, M.2
  • 101
  • 102
    • 77953811255 scopus 로고    scopus 로고
    • New approaches to population stratification in genome-wide association studies
    • Price AL, Zaitlen NA, Reich D, Patterson N (2010) New approaches to population stratification in genome-wide association studies. Nat Rev Genet 11, 459-463.
    • (2010) Nat Rev Genet , vol.11 , pp. 459-463
    • Price, A.L.1    Zaitlen, N.A.2    Reich, D.3    Patterson, N.4
  • 103
    • 42649088044 scopus 로고    scopus 로고
    • Principal component analysis of genetic data
    • Reich D, Price AL, Patterson N (2008) Principal component analysis of genetic data. Nat Genet 40, 491-492.
    • (2008) Nat Genet , vol.40 , pp. 491-492
    • Reich, D.1    Price, A.L.2    Patterson, N.3
  • 107
    • 74949092081 scopus 로고    scopus 로고
    • Detection of nonneutral substitution rates on mammalian phylogenies
    • Pollard KS, Hubisz MJ, Rosenbloom KR, Siepel A (2010) Detection of nonneutral substitution rates on mammalian phylogenies. Genome Res 20, 110-121.
    • (2010) Genome Res , vol.20 , pp. 110-121
    • Pollard, K.S.1    Hubisz, M.J.2    Rosenbloom, K.R.3    Siepel, A.4
  • 108
    • 68149165614 scopus 로고    scopus 로고
    • Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
    • Kumar P, Henikoff S, Ng PC (2009) Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat Protoc 4, 1073-1081.
    • (2009) Nat Protoc , vol.4 , pp. 1073-1081
    • Kumar, P.1    Henikoff, S.2    Ng, P.C.3
  • 109
    • 33750353461 scopus 로고    scopus 로고
    • Predicting the effects of amino acid substitutions on protein function
    • Ng PC, Henikoff S (2006) Predicting the effects of amino acid substitutions on protein function. Annu Rev Genomics Hum Genet 7, 61-80.
    • (2006) Annu Rev Genomics Hum Genet , vol.7 , pp. 61-80
    • Ng, P.C.1    Henikoff, S.2
  • 112
    • 84877087748 scopus 로고    scopus 로고
    • VT test http://genetics.bwh.harvard.edu/vt/dokuwiki/start.
    • VT Test
  • 113
    • 50949095168 scopus 로고    scopus 로고
    • Methods for detecting associations with rare variants for common diseases: Application to analysis of sequence data
    • Li B, Leal SM (2008) Methods for detecting associations with rare variants for common diseases: Application to analysis of sequence data. Am J Hum Genet 83, 311-321.
    • (2008) Am J Hum Genet , vol.83 , pp. 311-321
    • Li, B.1    Leal, S.M.2
  • 114
    • 61449168010 scopus 로고    scopus 로고
    • A groupwise association test for rare mutations using a weighted sum statistic
    • Madsen BE, Browning SR (2009) A groupwise association test for rare mutations using a weighted sum statistic. PlosGenet 5, e1000384.
    • (2009) PlosGenet , vol.5
    • Madsen, B.E.1    Browning, S.R.2
  • 122
    • 0037209210 scopus 로고    scopus 로고
    • Mitochondrial DNA polymorphisms associated with longevity in a Finnish population
    • Niemi AK, Hervonen A, Hurme M, Karhunen PJ, Jylha M, Majamaa K (2003) Mitochondrial DNA polymorphisms associated with longevity in a Finnish population. Hum Genet 112, 29-33.
    • (2003) Hum Genet , vol.112 , pp. 29-33
    • Niemi, A.K.1    Hervonen, A.2    Hurme, M.3    Karhunen, P.J.4    Jylha, M.5    Majamaa, K.6
  • 125
    • 44349132708 scopus 로고    scopus 로고
    • Common and rare variants in multifactorial susceptibility to common diseases
    • Bodmer W, Bonilla C (2008) Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet 40, 695-701.
    • (2008) Nat Genet , vol.40 , pp. 695-701
    • Bodmer, W.1    Bonilla, C.2
  • 126
    • 62549085618 scopus 로고    scopus 로고
    • Human genetic variation and its contribution to complex traits
    • Frazer KA, Murray SS, Schork NJ, Topol EJ (2009) Human genetic variation and its contribution to complex traits. Nat Rev Genet 10, 241-251.
    • (2009) Nat Rev Genet , vol.10 , pp. 241-251
    • Frazer, K.A.1    Murray, S.S.2    Schork, N.J.3    Topol, E.J.4
  • 129
    • 55449120805 scopus 로고    scopus 로고
    • Genetic mapping in human disease
    • Altshuler D, Daly MJ, Lander ES (2008) Genetic mapping in human disease. Science 322, 881-888.
    • (2008) Science , vol.322 , pp. 881-888
    • Altshuler, D.1    Daly, M.J.2    Lander, E.S.3
  • 130
    • 80052419584 scopus 로고    scopus 로고
    • The mechanism of superoxide production by the antimycininhibited mitochondrial Q-cycle
    • Quinlan CL, Gerencser AA, Treberg JR, Brand MD (2011) The mechanism of superoxide production by the antimycininhibited mitochondrial Q-cycle. J Biol Chem 286, 31361- 31372.
    • (2011) J Biol Chem , vol.286 , pp. 31361-31372
    • Quinlan, C.L.1    Gerencser, A.A.2    Treberg, J.R.3    Brand, M.D.4
  • 134
    • 79952105783 scopus 로고    scopus 로고
    • The biology of lysine acetylation integrates transcriptional programming and metabolism
    • Patel J, Pathak RR, Mujtaba S (2011) The biology of lysine acetylation integrates transcriptional programming and metabolism. Nutr Metab (Lond) 8, 12.
    • (2011) Nutr Metab (Lond , vol.8 , pp. 12
    • Patel, J.1    Pathak, R.R.2    Mujtaba, S.3
  • 137
    • 67649395959 scopus 로고    scopus 로고
    • Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals
    • Yu W, Lin Y, Yao J, Huang W, Lei Q, Xiong Y, Zhao S, Guan KL (2009) Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals. J Biol Chem 284, 13669-13675.
    • (2009) J Biol Chem , vol.284 , pp. 13669-13675
    • Yu, W.1    Lin, Y.2    Yao, J.3    Huang, W.4    Lei, Q.5    Xiong, Y.6    Zhao, S.7    Guan, K.L.8
  • 138
    • 0027360029 scopus 로고
    • The spectrum of mitochondrialDNAmutations in families with Leber hereditary optic neuroretinopathy
    • Huoponen K, Lamminen T, Juvonen V, Aula P, Nikoskelainen E, Savontaus ML (1993) The spectrum of mitochondrialDNAmutations in families with Leber hereditary optic neuroretinopathy. Hum Genet 92, 379-384.
    • (1993) Hum Genet , vol.92 , pp. 379-384
    • Huoponen, K.1    Lamminen, T.2    Juvonen, V.3    Aula, P.4    Nikoskelainen, E.5    Savontaus, M.L.6
  • 139
    • 55949084951 scopus 로고    scopus 로고
    • Mitochondrial variants may influence the phenotypic manifestationof Leber's hereditary optic neuropathy-associated ND4 G11778A mutation
    • Cai W, Fu Q, Zhou X, Qu J, Tong Y, Guan MX (2008) Mitochondrial variants may influence the phenotypic manifestationof Leber's hereditary optic neuropathy-associated ND4 G11778A mutation. J Genet Genomics 35, 649-655.
    • (2008) J Genet Genomics , vol.35 , pp. 649-655
    • Cai, W.1    Fu, Q.2    Zhou, X.3    Qu, J.4    Tong, Y.5    Guan, M.X.6
  • 141
    • 53649098737 scopus 로고    scopus 로고
    • Pathway analysis of seven common diseases assessed by genome-wide association
    • Torkamani A, Topol EJ, Schork NJ (2008) Pathway analysis of seven common diseases assessed by genome-wide association. Genomics 92, 265-272.
    • (2008) Genomics , vol.92 , pp. 265-272
    • Torkamani, A.1    Topol, E.J.2    Schork, N.J.3
  • 146
    • 0347356538 scopus 로고    scopus 로고
    • Effects of purifying and adaptive selection on regional variation in human mtDNA
    • Ruiz-Pesini E, Mishmar D, Brandon M, Procaccio V, Wallace DC (2004) Effects of purifying and adaptive selection on regional variation in human mtDNA. Science 303, 223- 226.
    • (2004) Science , vol.303 , pp. 223-226
    • Ruiz-Pesini, E.1    Mishmar, D.2    Brandon, M.3    Procaccio, V.4    Wallace, D.C.5
  • 147
    • 77649191873 scopus 로고    scopus 로고
    • Mitochondrial DNA copy number in peripheral blood is associated with cognitive function in apparently healthy elderly women
    • Lee JW, Park KD, Im JA, Kim MY, Lee DC (2010) Mitochondrial DNA copy number in peripheral blood is associated with cognitive function in apparently healthy elderly women. Clin Chim Acta 411, 592-596.
    • (2010) Clin Chim Acta , vol.411 , pp. 592-596
    • Lee, J.W.1    Park, K.D.2    Im, J.A.3    Kim, M.Y.4    Lee, D.C.5
  • 148
    • 0242499394 scopus 로고    scopus 로고
    • Environmental influences on epistatic interactions: Viabilities of cytochrome c genotypes in interpopulation crosses
    • Willett CS, Burton RS (2003) Environmental influences on epistatic interactions: Viabilities of cytochrome c genotypes in interpopulation crosses. Evolution 57, 2286-2292.
    • (2003) Evolution , vol.57 , pp. 2286-2292
    • Willett, C.S.1    Burton, R.S.2
  • 149
    • 0034805297 scopus 로고    scopus 로고
    • Sexually antagonistic cytonuclear fitness interactions in Drosophila melanogaster
    • Rand DM, Clark AG, Kann LM (2001) Sexually antagonistic cytonuclear fitness interactions in Drosophila melanogaster. Genetics 159, 173-187.
    • (2001) Genetics , vol.159 , pp. 173-187
    • Rand, D.M.1    Clark, A.G.2    Kann, L.M.3
  • 150
    • 33644771161 scopus 로고    scopus 로고
    • Nuclear-mitochondrial epistasis and drosophila aging: Introgression of Drosophila simulans mtDNA modifies longevity in D. melanogaster nuclear backgrounds
    • Rand DM, Fry A, Sheldahl L (2006) Nuclear-mitochondrial epistasis and drosophila aging: Introgression of Drosophila simulans mtDNA modifies longevity in D. melanogaster nuclear backgrounds. Genetics 172, 329-341.
    • (2006) Genetics , vol.172 , pp. 329-341
    • Rand, D.M.1    Fry, A.2    Sheldahl, L.3
  • 151
    • 8144226823 scopus 로고    scopus 로고
    • Cytonuclear coevolution: The genomics of cooperation
    • Rand DM, Haney RA, Fry AJ (2004) Cytonuclear coevolution: The genomics of cooperation. Trends Ecol Evol 19, 645-653.
    • (2004) Trends Ecol Evol , vol.19 , pp. 645-653
    • Rand, D.M.1    Haney, R.A.2    Fry, A.J.3
  • 152
    • 7344244917 scopus 로고    scopus 로고
    • Mutation and selection at silent and replacement sites in the evolution of animal mitochondrial DNA
    • Rand DM, Kann LM (1998) Mutation and selection at silent and replacement sites in the evolution of animal mitochondrial DNA. Genetica 102-103 393-407.
    • (1998) Genetica , vol.102-103 , pp. 393-407
    • Rand, D.M.1    Kann, L.M.2
  • 155
    • 79952445071 scopus 로고    scopus 로고
    • Mitochondrial-nuclear epistasis: Implications for human aging and longevity
    • Tranah GJ (2011) Mitochondrial-nuclear epistasis: Implications for human aging and longevity. Ageing Res Rev 10, 238-252.
    • (2011) Ageing Res Rev , vol.10 , pp. 238-252
    • Tranah, G.J.1
  • 156
    • 0029008318 scopus 로고
    • Competition between mitochondrial haplotypes in distinct nuclear genetic environments: Drosophila pseudoobscura vs. D. persimilis
    • Hutter CM, Rand DM (1995) Competition between mitochondrial haplotypes in distinct nuclear genetic environments: Drosophila pseudoobscura vs. D. persimilis. Genetics 140, 537-548.
    • (1995) Genetics , vol.140 , pp. 537-548
    • Hutter, C.M.1    Rand, D.M.2
  • 157
    • 0035056971 scopus 로고    scopus 로고
    • Evolution of nuclear- and mitochondrial-encoded subunit interaction in cytochrome c oxidase
    • Schmidt TR,WuW, Goodman M, Grossman LI (2001) Evolution of nuclear- And mitochondrial-encoded subunit interaction in cytochrome c oxidase. Mol Biol Evol 18, 563-569.
    • (2001) Mol Biol Evol , vol.18 , pp. 563-569
    • Schmidt, T.R.1    Wu, W.2    Goodman, M.3    Grossman, L.I.4
  • 158
    • 0036791993 scopus 로고    scopus 로고
    • Functional coadaptation between cytochrome c and cytochrome c oxidase withinallopatric populations of a marine copepod
    • Rawson PD, Burton RS (2002) Functional coadaptation between cytochrome c and cytochrome c oxidase withinallopatric populations of a marine copepod. Proc Natl Acad Sci U S A 99, 12955-12958.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 12955-12958
    • Rawson, P.D.1    Burton, R.S.2
  • 159
    • 33846479810 scopus 로고    scopus 로고
    • Intergenomic epistasis for fitness: Within-population interactions between cytoplasmic and nuclear genes in Drosophila melanogaster
    • DowlingDK,FribergU, Hailer F, ArnqvistG(2007) Intergenomic epistasis for fitness: Within-population interactions between cytoplasmic and nuclear genes in Drosophila melanogaster. Genetics 175, 235-244.
    • (2007) Genetics , vol.175 , pp. 235-244
    • Dowling, D.K.1    Friberg, U.2    Hailer, F.3    Arnqvist, G.4
  • 160
    • 34548096112 scopus 로고    scopus 로고
    • Contributions of heterosis and epistasis to hybrid fitness
    • Rhode JM, Cruzan MB (2005) Contributions of heterosis and epistasis to hybrid fitness. Am Nat 166, E124-E139.
    • (2005) Am Nat , vol.166
    • Rhode, J.M.1    Cruzan, M.B.2
  • 164
    • 40949095179 scopus 로고    scopus 로고
    • Hydroxytyrosol protects retinal pigment epithelial cells from acrolein-induced oxidative stress and mitochondrial dysfunction
    • Liu Z, Sun L, Zhu L, Jia X, Li X, Jia H, Wang Y, Weber P, Long J, Liu J (2007) Hydroxytyrosol protects retinal pigment epithelial cells from acrolein-induced oxidative stress and mitochondrial dysfunction. J Neurochem 103, 2690- 2700.
    • (2007) J Neurochem , vol.103 , pp. 2690-2700
    • Liu, Z.1    Sun, L.2    Zhu, L.3    Jia, X.4    Li, X.5    Jia, H.6    Wang, Y.7    Weber, P.8    Long, J.9    Liu, J.10
  • 165
    • 42449100009 scopus 로고    scopus 로고
    • Isoflavones promote mitochondrial biogenesis
    • Rasbach KA, Schnellmann RG (2008) Isoflavones promote mitochondrial biogenesis. J Pharmacol Exp Ther 325, 536- 543.
    • (2008) J Pharmacol Exp Ther , vol.325 , pp. 536-543
    • Rasbach, K.A.1    Schnellmann, R.G.2
  • 167
    • 73649125823 scopus 로고    scopus 로고
    • Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression
    • Chowanadisai W, Bauerly KA, Tchaparian E, Wong A, Cortopassi GA, Rucker RB (2010) Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. J Biol Chem 285, 142-152.
    • (2010) J Biol Chem , vol.285 , pp. 142-152
    • Chowanadisai, W.1    Bauerly, K.A.2    Tchaparian, E.3    Wong, A.4    Cortopassi, G.A.5    Rucker, R.B.6
  • 169
    • 38649132337 scopus 로고    scopus 로고
    • Mitochondria-A nexus for aging, calorie restriction, and sirtuins?
    • Guarente L (2008) Mitochondria-A nexus for aging, calorie restriction, and sirtuins? Cell 132, 171-176.
    • (2008) Cell , vol.132 , pp. 171-176
    • Guarente, L.1
  • 172
    • 39749128989 scopus 로고    scopus 로고
    • Resistance training, sarcopenia, and the mitochondrial theory of aging
    • Johnston AP, De Lisio M, Parise G (2008) Resistance training, sarcopenia, and the mitochondrial theory of aging. Appl Physiol Nutr Metab 33, 191-199.
    • (2008) Appl Physiol Nutr Metab , vol.33 , pp. 191-199
    • Johnston, A.P.1    De Lisio, M.2    Parise, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.