Mitochondrial variants may influence the phenotypic manifestation of Leber's hereditary optic neuropathy-associated ND4 G11778A mutation

Journal of Genetics and Genomics

Volumn 35, Issue 11, 2008, Pages 649-655

  Cai, Wanshi ^a   Fu, Qun ^b   Zhou, Xiangtian ^a   Qu, Jia ^a   Tong, Yi ^a,c   Guan, Min Xin ^a,d  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b XINXIANG MEDICAL UNIVERSITY   (China)

^c FUJIAN MEDICAL UNIVERSITY   (China)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Chinese; haplotype; Leber's hereditary optic neuropathy; mitochondrial DNA; modifier; mutation; vision loss

Indexed keywords

POLYPEPTIDE;

ADULT; ARTICLE; BLINDNESS; CLINICAL ARTICLE; FEMALE; GENE MUTATION; GENETIC VARIABILITY; HUMAN; LEBER HEREDITARY OPTIC NEUROPATHY; MALE; PHENOTYPE; VISUAL IMPAIRMENT;

ADOLESCENT; ADULT; BASE SEQUENCE; CHILD; CHINA; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; ETHNIC GROUPS; FEMALE; HUMANS; MALE; MITOCHONDRIA; MUTATION; NADH DEHYDROGENASE; OPTIC ATROPHY, HEREDITARY, LEBER; PEDIGREE; PHENOTYPE;

EID: 55949084951     PISSN: 16738527     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1673-8527(08)60086-7     Document Type: Article

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