Bioenergetics, the origins of complexity, and the ascent of man

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue SUPPL. 2, 2010, Pages 8947-8953

  Wallace, Douglas C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Common diseases; Evolution; Human origins; Mitochondria; Natural selection

Indexed keywords

CELL NUCLEUS DNA; MITOCHONDRIAL DNA; DNA;

BIOENERGY; GENE EXPRESSION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; NATURAL SELECTION; NONHUMAN; PRIORITY JOURNAL; REVIEW; ANIMAL; ARTICLE; CELL MEMBRANE POTENTIAL; CELL NUCLEUS; ELECTROCHEMISTRY; ENERGY METABOLISM; EVOLUTION; GENETIC SELECTION; METABOLISM; METHODOLOGY; MITOCHONDRION; MUTATION;

ANIMALIA;

ANIMALS; CELL NUCLEUS; DNA; ELECTROCHEMISTRY; ENERGY METABOLISM; EVOLUTION; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; MUTATION; SELECTION, GENETIC;

EID: 77952415166     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0914635107     Document Type: Review

References (46)

1. Darwin CR, Wallace AR (1858) On the tendency of species to form varieties; and on the perpetuation of varieties and species by natural means of selection. J Proc Linnean Soc Lond Zool 3:46-50.
2. Darwin C (1859) On the Origin of Species by Means of Natural Selection, or the Preservation of Favoured Races in the Struggle for Life (John Murray of Albemarle Street, London).
3. Simpson S (2003) Questioning the oldest signs of life. Sci Am 288:70-77.
4. Morowitz HJ (1968) Energy Flow in Biology, Biological Organization as a Problem in Thermal Physics (Academic, New York).
5. Rubí JM (2008) The long arm of the second law. Sci Am 299:62-67.
6. Ricardo A, Szostak JW (2009) Origin of life on earth. Sci Am 301:54-61.
7. Wallace DC (2007) Why do we still have a maternally inherited mitochondrial DNA? Insights from evolutionary medicine. Annu Rev Biochem 76:781-821.
8. Mishmar D, et al. (2006) Adaptive selection of mitochondrial complex I subunits during primate radiation. Gene 378:11-18. (Pubitemid 44108461)
9. Lane N (2009) Biodiversity: On the origin of bar codes. Nature 462:272-274.
10. Wallace DC, Fan W (2010) Energetics, epigenetics, mitochondrial genetics. Mitochondrion 10:12-31.
11. Abzhanov A, et al. (2006) The calmodulin pathway and evolution of elongated beak morphology in Darwin's finches. Nature 442:563-567. (Pubitemid 44167914)
12. Chan YF, et al. (2010) Adaptive evolution of pelvic reduction in sticklebacks by recurrent deletion of a Pitx1 enhancer. Science 327:302-305.
13. Brown WM, Prager EM, Wang A, Wilson AC (1982) Mitochondrial DNA sequences of primates: Tempo and mode of evolution. J Mol Evol 18:225-239. (Pubitemid 12024171)
14. Neckelmann N, Li K, Wade RP, Shuster R, Wallace DC (1987) cDNA sequence of a human skeletal muscle ADP/ATP translocator: Lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes. Proc Natl Acad Sci USA 84:7580-7584.
15. Wallace DC, et al. (1987) Sequence analysis of cDNAs for the human and bovine ATP synthase beta subunit: Mitochondrial DNA genes sustain seventeen times more mutations. Curr Genet 12:81-90.
16. Wallace DC, Lott MT, Procaccio V (2007) Emery and Rimoin's Principles and Practice of Medical Genetics, eds Rimoin DL, Connor JM, Pyeritz RE, Korf BR (Churchill Livingstone Elsevier, Philadelphia), 5th Ed, pp 194-298.
17. Wallace DC (2005) A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine. Annu Rev Genet 39:359-407.
18. Wallace DC, Fan W, Procaccio V (2010) Mitochondrial energetics and therapeutics. Annu Rev Pathol 5:297-348.
19. Schaefer AM, et al. (2008) Prevalence of mitochondrial DNA disease in adults. Ann Neurol 63:35-39.
20. Elliott HR, Samuels DC, Eden JA, Relton CL, Chinnery PF (2008) Pathogenic mitochondrial DNA mutations are common in the general population. Am J Hum Genet 83:254-260.
21. Fan W, et al. (2008) A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations. Science 319:958-962. (Pubitemid 351263767)
22. Stewart JB, et al. (2008) Strong purifying selection in transmission of mammalian mitochondrial DNA. PLoS Biol 6:0063-0071.
23. Johnson MJ, Wallace DC, Ferris SD, Rattazzi MC, Cavalli-Sforza LL (1983) Radiation of human mitochondria DNA types analyzed by restriction endonuclease cleavage patterns. J Mol Evol 19:255-271.
24. Cann RL, Stoneking M, Wilson AC (1987) Mitochondrial DNA and human evolution. Nature 325:31-36. (Pubitemid 17263533)
25. Merriwether DA, et al. (1991) The structure of human mitochondrial DNA variation. J Mol Evol 33:543-555.
26. Balloux F, Handley LJ, Jombart T, Liu H, Manica A (2009) Climate shaped the worldwide distribution of human mitochondrial DNA sequence variation. Proc Biol Sci 276:3447-3455.
27. Kazuno AA, et al. (2006) Identification of mitochondrial DNA polymorphisms that alter mitochondrial matrix pH and intracellular calcium dynamics. PLoS Genet 2:1167-1177.
28. Suissa S, et al. (2009) Ancient mtDNA genetic variants modulate mtDNA transcription and replication. PLoS Genet 5:e1000474.
29. Wallace DC, Fan W (2009) The pathophysiology of mitochondrial disease as modeled in the mouse. Genes Dev 23:1714-1736.
30. Villarroya F, Iglesias R, Giralt M (2006) PPARs in the control of uncoupling proteins gene expression. PPAR Res 2007:1-12.
31. Nakano T, et al. (2006) A/G heterozygote of the A-3826G polymorphism in the UCP-1 gene has higher BMI than A/A and G/G homozygote in young Japanese males. J Med Invest 53:218-222. (Pubitemid 44619839)
32. Bulotta A, et al. (2005) The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy. J Clin Endocrinol Metab 90:1176-1180. (Pubitemid 40279251)
33. Cha MH, Shin HD, Kim KS, Lee BH, Yoon Y (2006) The effects of uncoupling protein 3 haplotypes on obesity phenotypes and very low-energy diet-induced changes among overweight Korean female subjects. Metabolism 55:578-586.
34. Altshuler D, et al. (2000) The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26:76-80.
35. Ek J, et al. (2001) Mutation analysis of peroxisome proliferator- activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to type II diabetes mellitus. Diabetologia 44:2220-2226. (Pubitemid 34015475)
36. Muller YL, Bogardus C, Pedersen O, Baier L (2003) A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians. Diabetes 52:895-898. (Pubitemid 36323602)
37. Saxena R, et al., Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316:1331-1336.
38. Zeggini E, et al., Wellcome Trust Case Control Consortium (WTCCC) (2007) Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316:1336-1341. (Pubitemid 46871654)
39. Scott LJ, et al. (2007) A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316:1341-1345.
40. Sladek R, et al. (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445:881-885. (Pubitemid 46309843)
41. Madiraju P, Pande SV, Prentki M, Madiraju SR (2009) Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation. Epigenetics 4:399-403.
42. Feinberg AP (2007) Phenotypic plasticity and the epigenetics of human disease. Nature 447:433-440.
43. Loat CS, et al. (2008) Methyl-CpG-binding protein 2 polymorphisms and vulnerability to autism. Genes Brain Behav 7:754-760.
44. Wallace DC (2009) Mitochondria, bioenergetics, and the epigenome in eukaryotic and human evolution. Cold Spring Harb Symp Quant Biol, ePub ahead of print, http://symposium.cshlp.org/content/early/2009/11/25/sqb.2009.74.031.
45. Kemp M, Go YM, Jones DP (2008) Nonequilibrium thermodynamics of thiol/disulfide redox systems: A perspective on redox systems biology. Free Radic Biol Med 44:921-937.
46. Semenza GL (2008) Mitochondrial autophagy: Life and breath of the cell. Autophagy 4:534-536.