-
1
-
-
52949085102
-
Induction of NAD(P)H: Quinone reductase by rutaecarpine isolated from the fruits of Evodia rutaecarpa in the murine hepatic Hepa-1c1c7 cell line
-
Ahn H, Nam JW, Seo EK, Mar W,. 2008. Induction of NAD(P)H: quinone reductase by rutaecarpine isolated from the fruits of Evodia rutaecarpa in the murine hepatic Hepa-1c1c7 cell line. Planta Med 74: 1387-1390.
-
(2008)
Planta Med
, vol.74
, pp. 1387-1390
-
-
Ahn, H.1
Nam, J.W.2
Seo, E.K.3
Mar, W.4
-
2
-
-
4444241129
-
Norcantharidin induces human melanoma A375-S2 cell apoptosis through mitochondrial and caspase pathways
-
An WW, Wang MW, Tashiro S, Onodera S, Ikejima T,. 2004. Norcantharidin induces human melanoma A375-S2 cell apoptosis through mitochondrial and caspase pathways. J Korean Med Sci 19: 560-566.
-
(2004)
J Korean Med Sci
, vol.19
, pp. 560-566
-
-
An, W.W.1
Wang, M.W.2
Tashiro, S.3
Onodera, S.4
Ikejima, T.5
-
3
-
-
0035031195
-
Introduction: The history of arsenic trioxide in cancer therapy
-
Antman KH,. 2001. Introduction: the history of arsenic trioxide in cancer therapy. Oncologist 6 (Suppl 2): 1-2.
-
(2001)
Oncologist
, vol.6
, Issue.SUPPL. 2
, pp. 1-2
-
-
Antman, K.H.1
-
4
-
-
12244266074
-
A new P-glycoprotein inhibitor from the caper spurge (Euphorbia lathyris)
-
Appendino G, Della Porta C, Conseil G, et al,. 2003. A new P-glycoprotein inhibitor from the caper spurge (Euphorbia lathyris). J Nat Prod 66: 140-142.
-
(2003)
J Nat Prod
, vol.66
, pp. 140-142
-
-
Appendino, G.1
Della Porta, C.2
Conseil, G.3
-
5
-
-
0035985485
-
Arsenic trioxide and breast cancer: Analysis of the apoptotic, differentiative and immunomodulatory effects
-
Baj G, Arnulfo A, Deaglio S, et al,. 2002. Arsenic trioxide and breast cancer: analysis of the apoptotic, differentiative and immunomodulatory effects. Breast Cancer Res Treat 73: 61-73.
-
(2002)
Breast Cancer Res Treat
, vol.73
, pp. 61-73
-
-
Baj, G.1
Arnulfo, A.2
Deaglio, S.3
-
6
-
-
67649366436
-
Novel camptothecin derivatives as topoisomerase i inhibitors
-
Basili S, Moro S,. 2009. Novel camptothecin derivatives as topoisomerase I inhibitors. Expert Opin Ther Pat 19: 555-574.
-
(2009)
Expert Opin Ther Pat
, vol.19
, pp. 555-574
-
-
Basili, S.1
Moro, S.2
-
7
-
-
78649671801
-
The synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity
-
Batova A, Altomare D, Chantarasriwong O, et al,. 2010. The synthetic caged garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity. Mol Cancer Ther 9: 2869-2878.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 2869-2878
-
-
Batova, A.1
Altomare, D.2
Chantarasriwong, O.3
-
8
-
-
78650958235
-
Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway
-
Beauchamp EM, Ringer L, Bulut G, et al,. 2011. Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway. J Clin Invest 121: 148-160.
-
(2011)
J Clin Invest
, vol.121
, pp. 148-160
-
-
Beauchamp, E.M.1
Ringer, L.2
Bulut, G.3
-
9
-
-
68149181774
-
Pro-apoptotic and cytostatic activity of naturally occurring cardenolides
-
Bloise E, Braca A, De Tommasi N, et al,. 2009. Pro-apoptotic and cytostatic activity of naturally occurring cardenolides. Cancer Chemother Pharmacol 64: 793-802.
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, pp. 793-802
-
-
Bloise, E.1
Braca, A.2
De Tommasi, N.3
-
10
-
-
68749098702
-
The effects of telocinobufagin isolated from Chan Su on the activation and cytokine secretion of immunocytes in vitro
-
Cao Y, Song Y, An N, et al,. 2009. The effects of telocinobufagin isolated from Chan Su on the activation and cytokine secretion of immunocytes in vitro. Fundam Clin Pharmacol 23: 457-464.
-
(2009)
Fundam Clin Pharmacol
, vol.23
, pp. 457-464
-
-
Cao, Y.1
Song, Y.2
An, N.3
-
11
-
-
33745944185
-
Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells
-
Carter BZ, Mak DH, Schober WD, et al,. 2006. Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells. Blood 108: 630-637.
-
(2006)
Blood
, vol.108
, pp. 630-637
-
-
Carter, B.Z.1
Mak, D.H.2
Schober, W.D.3
-
12
-
-
66349130754
-
Evodiamine stabilizes topoisomerase I-DNA cleavable complex to inhibit topoisomerase i activity
-
Chan AL, Chang WS, Chen LM, et al,. 2009. Evodiamine stabilizes topoisomerase I-DNA cleavable complex to inhibit topoisomerase I activity. Molecules 14: 1342-1352.
-
(2009)
Molecules
, vol.14
, pp. 1342-1352
-
-
Chan, A.L.1
Chang, W.S.2
Chen, L.M.3
-
13
-
-
34247897057
-
Dosage effects of ginkgolide B on ethanol-induced cell death in human hepatoma G2 cells
-
Chan WH, Hsuuw YD,. 2007. Dosage effects of ginkgolide B on ethanol-induced cell death in human hepatoma G2 cells. Ann N Y Acad Sci 1095: 388-398.
-
(2007)
Ann N y Acad Sci
, vol.1095
, pp. 388-398
-
-
Chan, W.H.1
Hsuuw, Y.D.2
-
14
-
-
78049500375
-
Involvement of mitochondrial pathway in NCTD-induced cytotoxicity in human hepG2 cells
-
Chang C, Zhu YQ, Mei JJ, Liu SQ, Luo J,. 2010. Involvement of mitochondrial pathway in NCTD-induced cytotoxicity in human hepG2 cells. J Exp Clin Cancer Res 29: 145.
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 145
-
-
Chang, C.1
Zhu, Y.Q.2
Mei, J.J.3
Liu, S.Q.4
Luo, J.5
-
15
-
-
40949102139
-
Rapid identification of oleanane-type saponins in the roots of Stephanotis mucronata by liquid chromatography/electrospray tandem mass spectrometry
-
Chen J, Ye Y, Sun C, Pan Y,. 2008. Rapid identification of oleanane-type saponins in the roots of Stephanotis mucronata by liquid chromatography/ electrospray tandem mass spectrometry. Anal Chim Acta 613: 74-82.
-
(2008)
Anal Chim Acta
, vol.613
, pp. 74-82
-
-
Chen, J.1
Ye, Y.2
Sun, C.3
Pan, Y.4
-
16
-
-
70249142794
-
A small-molecule metastasis inhibitor, norcantharidin, downregulates matrix metalloproteinase-9 expression by inhibiting Sp1 transcriptional activity in colorectal cancer cells
-
Chen YJ, Chang WM, Liu YW, et al,. 2009. A small-molecule metastasis inhibitor, norcantharidin, downregulates matrix metalloproteinase-9 expression by inhibiting Sp1 transcriptional activity in colorectal cancer cells. Chem Biol Interact 181: 440-446.
-
(2009)
Chem Biol Interact
, vol.181
, pp. 440-446
-
-
Chen, Y.J.1
Chang, W.M.2
Liu, Y.W.3
-
17
-
-
14144249977
-
Inhibitory effect of norcantharidin, a derivative compound from blister beetles, on tumor invasion and metastasis in CT26 colorectal adenocarcinoma cells
-
Chen YJ, Shieh CJ, Tsai TH, et al,. 2005. Inhibitory effect of norcantharidin, a derivative compound from blister beetles, on tumor invasion and metastasis in CT26 colorectal adenocarcinoma cells. Anticancer Drugs 16: 293-299.
-
(2005)
Anticancer Drugs
, vol.16
, pp. 293-299
-
-
Chen, Y.J.1
Shieh, C.J.2
Tsai, T.H.3
-
18
-
-
11144295689
-
Polyphyllin D is a potent apoptosis inducer in drug-resistant HepG2 cells
-
Cheung JY, Ong RC, Suen YK, et al,. 2005. Polyphyllin D is a potent apoptosis inducer in drug-resistant HepG2 cells. Cancer Lett 217: 203-211.
-
(2005)
Cancer Lett
, vol.217
, pp. 203-211
-
-
Cheung, J.Y.1
Ong, R.C.2
Suen, Y.K.3
-
19
-
-
75349101846
-
L-type calcium channel blockers reverse docetaxel and vincristine-induced multidrug resistance independent of ABCB1 expression in human lung cancer cell lines
-
Chiu LY, Ko JL, Lee YJ, Yang TY, Tee YT, Sheu GT,. 2010. L-type calcium channel blockers reverse docetaxel and vincristine-induced multidrug resistance independent of ABCB1 expression in human lung cancer cell lines. Toxicol Lett 192: 408-418.
-
(2010)
Toxicol Lett
, vol.192
, pp. 408-418
-
-
Chiu, L.Y.1
Ko, J.L.2
Lee, Y.J.3
Yang, T.Y.4
Tee, Y.T.5
Sheu, G.T.6
-
20
-
-
77954513679
-
Euphorbiasteroid reverses P-glycoprotein-mediated multi-drug resistance in human sarcoma cell line MES-SA/Dx5
-
Choi JS, Kang NS, Min YK, Kim SH,. 2010. Euphorbiasteroid reverses P-glycoprotein-mediated multi-drug resistance in human sarcoma cell line MES-SA/Dx5. Phytother Res 24: 1042-1046.
-
(2010)
Phytother Res
, vol.24
, pp. 1042-1046
-
-
Choi, J.S.1
Kang, N.S.2
Min, Y.K.3
Kim, S.H.4
-
21
-
-
1442285458
-
Antitumor activity of bruceantin: An old drug with new promise
-
Cuendet M, Pezzuto JM,. 2004. Antitumor activity of bruceantin: an old drug with new promise. J Nat Prod 67: 269-272.
-
(2004)
J Nat Prod
, vol.67
, pp. 269-272
-
-
Cuendet, M.1
Pezzuto, J.M.2
-
22
-
-
0031810637
-
Podophyllotoxins: Current status and recent developments
-
Damayanthi Y, Lown JW,. 1998. Podophyllotoxins: current status and recent developments. Curr Med Chem 5: 205-252.
-
(1998)
Curr Med Chem
, vol.5
, pp. 205-252
-
-
Damayanthi, Y.1
Lown, J.W.2
-
24
-
-
33646785767
-
The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism
-
Deng XK, Yin W, Li WD, et al,. 2006b. The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism. J Ethnopharmacol 106: 179-186.
-
(2006)
J Ethnopharmacol
, vol.106
, pp. 179-186
-
-
Deng, X.K.1
Yin, W.2
Li, W.D.3
-
25
-
-
63449135103
-
The effect of cantharidins on leukemic stem cells
-
Dorn DC, Kou CA, Png KJ, Moore MA,. 2009. The effect of cantharidins on leukemic stem cells. Int J Cancer 124: 2186-2199.
-
(2009)
Int J Cancer
, vol.124
, pp. 2186-2199
-
-
Dorn, D.C.1
Kou, C.A.2
Png, K.J.3
Moore, M.A.4
-
26
-
-
0035007008
-
Arsenic compounds induce cytotoxicity and apoptosis in cisplatin-sensitive and -resistant gynecological cancer cell lines
-
Du YH, Ho PC,. 2001. Arsenic compounds induce cytotoxicity and apoptosis in cisplatin-sensitive and -resistant gynecological cancer cell lines. Cancer Chemother Pharmacol 47: 481-490.
-
(2001)
Cancer Chemother Pharmacol
, vol.47
, pp. 481-490
-
-
Du, Y.H.1
Ho, P.C.2
-
27
-
-
79960655721
-
Periplocin extracted from cortex periplocae induces apoptosis of SW480 cells through inhibiting the Wnt/beta-catenin signaling pathway
-
Du YY, Liu X, Shan BE,. 2009. Periplocin extracted from cortex periplocae induces apoptosis of SW480 cells through inhibiting the Wnt/beta-catenin signaling pathway. Ai Zheng 28: 456-460.
-
(2009)
Ai Zheng
, vol.28
, pp. 456-460
-
-
Du, Y.Y.1
Liu, X.2
Shan, B.E.3
-
28
-
-
13844267553
-
Molecular modes of action of cantharidin in tumor cells
-
Efferth T, Rauh R, Kahl S, et al,. 2005. Molecular modes of action of cantharidin in tumor cells. Biochem Pharmacol 69: 811-818.
-
(2005)
Biochem Pharmacol
, vol.69
, pp. 811-818
-
-
Efferth, T.1
Rauh, R.2
Kahl, S.3
-
29
-
-
33846967813
-
Inhibitory effect of norcantharidin on the growth of human gallbladder carcinoma GBC-SD cells in vitro
-
Fan YZ, Fu JY, Zhao ZM, Chen CQ,. 2007. Inhibitory effect of norcantharidin on the growth of human gallbladder carcinoma GBC-SD cells in vitro. Hepatobiliary Pancreat Dis Int 6: 72-80.
-
(2007)
Hepatobiliary Pancreat Dis Int
, vol.6
, pp. 72-80
-
-
Fan, Y.Z.1
Fu, J.Y.2
Zhao, Z.M.3
Chen, C.Q.4
-
30
-
-
39049187579
-
Anti-tumor mechanism of norcantharidin for the implanted tumors of human gallbladder carcinoma in nude mice in vivo
-
Fan YZ, Zhao ZM, Fu JY, Chen CQ,. 2006. Anti-tumor mechanism of norcantharidin for the implanted tumors of human gallbladder carcinoma in nude mice in vivo. Zhonghua Wai Ke Za Zhi 44: 618-622.
-
(2006)
Zhonghua Wai Ke Za Zhi
, vol.44
, pp. 618-622
-
-
Fan, Y.Z.1
Zhao, Z.M.2
Fu, J.Y.3
Chen, C.Q.4
-
31
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM,. 2010. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127: 2893-2917.
-
(2010)
Int J Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
32
-
-
34247245667
-
3) induced calcium signals and cytotoxicity in two human cell lines: SY-5Y neuroblastoma and 293 embryonic kidney (HEK)
-
3) induced calcium signals and cytotoxicity in two human cell lines: SY-5Y neuroblastoma and 293 embryonic kidney (HEK). Toxicol Appl Pharmacol 220: 292-301.
-
(2007)
Toxicol Appl Pharmacol
, vol.220
, pp. 292-301
-
-
Florea, A.M.1
Splettstoesser, F.2
Busselberg, D.3
-
33
-
-
0033662352
-
Antitumor properties of podophyllotoxin and related compounds
-
Gordaliza M, Castro MA, del Corral JM, Feliciano AS,. 2000. Antitumor properties of podophyllotoxin and related compounds. Curr Pharm Des 6: 1811-1839.
-
(2000)
Curr Pharm des
, vol.6
, pp. 1811-1839
-
-
Gordaliza, M.1
Castro, M.A.2
Del Corral, J.M.3
Feliciano, A.S.4
-
34
-
-
0037394265
-
Toad venom poisoning: Resemblance to digoxin toxicity and therapeutic implications
-
Gowda RM, Cohen RA, Khan IA,. 2003. Toad venom poisoning: resemblance to digoxin toxicity and therapeutic implications. Heart 89: e14.
-
(2003)
Heart
, vol.89
-
-
Gowda, R.M.1
Cohen, R.A.2
Khan, I.A.3
-
35
-
-
33947235679
-
Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine
-
Groth-Pedersen L, Ostenfeld MS, Hoyer-Hansen M, Nylandsted J, Jaattela M,. 2007. Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine. Cancer Res 67: 2217-2225.
-
(2007)
Cancer Res
, vol.67
, pp. 2217-2225
-
-
Groth-Pedersen, L.1
Ostenfeld, M.S.2
Hoyer-Hansen, M.3
Nylandsted, J.4
Jaattela, M.5
-
36
-
-
43249108681
-
Active pharmaceutical ingredients and mechanisms underlying phasic myometrial contractions stimulated with the saponin extract from Paris polyphylla Sm. var. yunnanensis used for abnormal uterine bleeding
-
Guo L, Su J, Deng BW, et al,. 2008. Active pharmaceutical ingredients and mechanisms underlying phasic myometrial contractions stimulated with the saponin extract from Paris polyphylla Sm. var. yunnanensis used for abnormal uterine bleeding. Hum Reprod 23: 964-971.
-
(2008)
Hum Reprod
, vol.23
, pp. 964-971
-
-
Guo, L.1
Su, J.2
Deng, B.W.3
-
37
-
-
31844434032
-
Inhibition of human telomerase reverse transcriptase gene expression by gambogic acid in human hepatoma SMMC-7721 cells
-
Guo QL, Lin SS, You QD, et al,. 2006. Inhibition of human telomerase reverse transcriptase gene expression by gambogic acid in human hepatoma SMMC-7721 cells. Life Sci 78: 1238-1245.
-
(2006)
Life Sci
, vol.78
, pp. 1238-1245
-
-
Guo, Q.L.1
Lin, S.S.2
You, Q.D.3
-
38
-
-
77952660167
-
Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines
-
Hahnvajanawong C, Boonyanugomol W, Nasomyon T, et al,. 2010. Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines. World J Gastroenterol 16: 2235-2243.
-
(2010)
World J Gastroenterol
, vol.16
, pp. 2235-2243
-
-
Hahnvajanawong, C.1
Boonyanugomol, W.2
Nasomyon, T.3
-
39
-
-
32044466747
-
Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi
-
Han QB, Wang YL, Yang L, et al,. 2006a. Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi. Chem Pharm Bull(Tokyo) 54: 265-267.
-
(2006)
Chem Pharm Bull(Tokyo)
, vol.54
, pp. 265-267
-
-
Han, Q.B.1
Wang, Y.L.2
Yang, L.3
-
40
-
-
33645011267
-
Gambogic acid and epigambogic acid, C-2 epimers with novel anticancer effects from Garcinia hanburyi
-
Han Q, Yang L, Liu Y, et al,. 2006b. Gambogic acid and epigambogic acid, C-2 epimers with novel anticancer effects from Garcinia hanburyi. Planta Med 72: 281-284.
-
(2006)
Planta Med
, vol.72
, pp. 281-284
-
-
Han, Q.1
Yang, L.2
Liu, Y.3
-
41
-
-
31544434864
-
A pair of novel cytotoxic polyprenylated xanthone epimers from gamboges
-
Han QB, Yang L, Wang YL, et al,. 2006c. A pair of novel cytotoxic polyprenylated xanthone epimers from gamboges. Chem Biodivers 3: 101-105.
-
(2006)
Chem Biodivers
, vol.3
, pp. 101-105
-
-
Han, Q.B.1
Yang, L.2
Wang, Y.L.3
-
42
-
-
70449412700
-
The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma
-
He D, Xu Q, Yan M, et al,. 2009. The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma. BMC Cancer 9: 343.
-
(2009)
BMC Cancer
, vol.9
, pp. 343
-
-
He, D.1
Xu, Q.2
Yan, M.3
-
43
-
-
76149099282
-
Daphnane diterpene esters with anti-proliferative activities against human lung cancer cells from Daphne genkwa
-
Hong JY, Nam JW, Seo EK, Lee SK,. 2010. Daphnane diterpene esters with anti-proliferative activities against human lung cancer cells from Daphne genkwa. Chem Pharm Bull(Tokyo) 58: 234-237.
-
(2010)
Chem Pharm Bull(Tokyo)
, vol.58
, pp. 234-237
-
-
Hong, J.Y.1
Nam, J.W.2
Seo, E.K.3
Lee, S.K.4
-
44
-
-
33646751454
-
Cantharidin-induced cytotoxicity and cyclooxygenase 2 expression in human bladder carcinoma cell line
-
Huan SK, Lee HH, Liu DZ, Wu CC, Wang CC,. 2006. Cantharidin-induced cytotoxicity and cyclooxygenase 2 expression in human bladder carcinoma cell line. Toxicology 223: 136-143.
-
(2006)
Toxicology
, vol.223
, pp. 136-143
-
-
Huan, S.K.1
Lee, H.H.2
Liu, D.Z.3
Wu, C.C.4
Wang, C.C.5
-
45
-
-
80052644944
-
Evidence for improved neuropharmacological efficacy and decreased neurotoxicity in mice with traditional processing of Rhizoma Arisaematis
-
Huang CF, Yang RS, Liu SH, Hsieh PC, Lin-Shiau SY,. 2011. Evidence for improved neuropharmacological efficacy and decreased neurotoxicity in mice with traditional processing of Rhizoma Arisaematis. Am J Chin Med 39: 981-998.
-
(2011)
Am J Chin Med
, vol.39
, pp. 981-998
-
-
Huang, C.F.1
Yang, R.S.2
Liu, S.H.3
Hsieh, P.C.4
Lin-Shiau, S.Y.5
-
46
-
-
2342535824
-
Roles of p38 and JNK mitogen-activated protein kinase pathways during cantharidin-induced apoptosis in U937 cells
-
Huh JE, Kang KS, Chae C, Kim HM, Ahn KS, Kim SH,. 2004. Roles of p38 and JNK mitogen-activated protein kinase pathways during cantharidin-induced apoptosis in U937 cells. Biochem Pharmacol 67: 1811-1818.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 1811-1818
-
-
Huh, J.E.1
Kang, K.S.2
Chae, C.3
Kim, H.M.4
Ahn, K.S.5
Kim, S.H.6
-
47
-
-
33845366080
-
Structure of lasiansine from Aconitumnagarum var. lasiandrum
-
Ji H, Wang FP,. 2006. Structure of lasiansine from Aconitumnagarum var. lasiandrum. J Asian Nat Prod Res 8: 619-624.
-
(2006)
J Asian Nat Prod Res
, vol.8
, pp. 619-624
-
-
Ji, H.1
Wang, F.P.2
-
48
-
-
85047700175
-
Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells
-
Jiang XH, Wong BC, Lin MC, et al,. 2001a. Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells. Oncogene 20: 8009-8018.
-
(2001)
Oncogene
, vol.20
, pp. 8009-8018
-
-
Jiang, X.H.1
Wong, B.C.2
Lin, M.C.3
-
49
-
-
0035863397
-
Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3
-
Jiang XH, Wong BC, Yuen ST, et al,. 2001b. Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3. Int J Cancer 91: 173-179.
-
(2001)
Int J Cancer
, vol.91
, pp. 173-179
-
-
Jiang, X.H.1
Wong, B.C.2
Yuen, S.T.3
-
50
-
-
66449129065
-
Lathyrane diterpenes from Euphorbia lathyris as modulators of multidrug resistance and their crystal structures
-
Jiao W, Dong W, Li Z, Deng M, Lu R,. 2009. Lathyrane diterpenes from Euphorbia lathyris as modulators of multidrug resistance and their crystal structures. Bioorg Med Chem 17: 4786-4792.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 4786-4792
-
-
Jiao, W.1
Dong, W.2
Li, Z.3
Deng, M.4
Lu, R.5
-
51
-
-
34548606496
-
TIEG1 induces apoptosis through mitochondrial apoptotic pathway and promotes apoptosis induced by homoharringtonine and velcade
-
Jin W, Di G, Li J, et al,. 2007. TIEG1 induces apoptosis through mitochondrial apoptotic pathway and promotes apoptosis induced by homoharringtonine and velcade. FEBS Lett 581: 3826-3832.
-
(2007)
FEBS Lett
, vol.581
, pp. 3826-3832
-
-
Jin, W.1
Di, G.2
Li, J.3
-
52
-
-
67449095163
-
Activity of triptolide against human mast cells harboring the kinase domain mutant KIT
-
Jin Y, Chen Q, Shi X, et al,. 2009. Activity of triptolide against human mast cells harboring the kinase domain mutant KIT. Cancer Sci 100: 1335-1343.
-
(2009)
Cancer Sci
, vol.100
, pp. 1335-1343
-
-
Jin, Y.1
Chen, Q.2
Shi, X.3
-
53
-
-
73949151915
-
The antitumor activity of homoharringtonine against human mast cells harboring the KIT D816V mutation
-
Jin Y, Lu Z, Cao K, et al,. 2010. The antitumor activity of homoharringtonine against human mast cells harboring the KIT D816V mutation. Mol Cancer Ther 9: 211-223.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 211-223
-
-
Jin, Y.1
Lu, Z.2
Cao, K.3
-
54
-
-
49649085319
-
The role of p38 MAPK and JNK in arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells
-
Kang YH, Lee SJ,. 2008. The role of p38 MAPK and JNK in arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells. J Cell Physiol 217: 23-33.
-
(2008)
J Cell Physiol
, vol.217
, pp. 23-33
-
-
Kang, Y.H.1
Lee, S.J.2
-
55
-
-
10844264632
-
Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: Reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria
-
Kang YH, Yi MJ, Kim MJ, et al,. 2004. Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria. Cancer Res 64: 8960-8967.
-
(2004)
Cancer Res
, vol.64
, pp. 8960-8967
-
-
Kang, Y.H.1
Yi, M.J.2
Kim, M.J.3
-
56
-
-
0035883408
-
Homoharringtonine: History, current research, and future direction
-
Kantarjian HM, Talpaz M, Santini V, Murgo A, Cheson B, O'Brien SM,. 2001. Homoharringtonine: history, current research, and future direction. Cancer 92: 1591-1605.
-
(2001)
Cancer
, vol.92
, pp. 1591-1605
-
-
Kantarjian, H.M.1
Talpaz, M.2
Santini, V.3
Murgo, A.4
Cheson, B.5
O'Brien, S.M.6
-
57
-
-
0036023433
-
Antiproliferative and proapoptotic activities of triptolide (PG490), a natural product entering clinical trials, on primary cultures of human prostatic epithelial cells
-
Kiviharju TM, Lecane PS, Sellers RG, Peehl DM,. 2002. Antiproliferative and proapoptotic activities of triptolide (PG490), a natural product entering clinical trials, on primary cultures of human prostatic epithelial cells. Clin Cancer Res 8: 2666-2674.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2666-2674
-
-
Kiviharju, T.M.1
Lecane, P.S.2
Sellers, R.G.3
Peehl, D.M.4
-
58
-
-
33847069296
-
Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene
-
Ko JK, Leung WC, Ho WK, Chiu P,. 2007. Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene. Eur J Pharmacol 559: 1-13.
-
(2007)
Eur J Pharmacol
, vol.559
, pp. 1-13
-
-
Ko, J.K.1
Leung, W.C.2
Ho, W.K.3
Chiu, P.4
-
59
-
-
67349190115
-
Bruceine D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase
-
Lau ST, Lin ZX, Liao Y, Zhao M, Cheng CH, Leung PS,. 2009. Bruceine D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase. Cancer Lett 281: 42-52.
-
(2009)
Cancer Lett
, vol.281
, pp. 42-52
-
-
Lau, S.T.1
Lin, Z.X.2
Liao, Y.3
Zhao, M.4
Cheng, C.H.5
Leung, P.S.6
-
60
-
-
0036675141
-
Cytotoxic sesquiterpene lactones from Carpesium abrotanoides
-
Lee J, Min B, Lee S, et al,. 2002. Cytotoxic sesquiterpene lactones from Carpesium abrotanoides. Planta Med 68: 745-747.
-
(2002)
Planta Med
, vol.68
, pp. 745-747
-
-
Lee, J.1
Min, B.2
Lee, S.3
-
61
-
-
62849095014
-
Formosanin C-induced apoptosis requires activation of caspase-2 and change of mitochondrial membrane potential
-
Lee JC, Su CL, Chen LL, Won SJ,. 2009. Formosanin C-induced apoptosis requires activation of caspase-2 and change of mitochondrial membrane potential. Cancer Sci 100: 503-513.
-
(2009)
Cancer Sci
, vol.100
, pp. 503-513
-
-
Lee, J.C.1
Su, C.L.2
Chen, L.L.3
Won, S.J.4
-
62
-
-
33646422206
-
Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft
-
Lee MS, Yuet-Wa JC, Kong SK, et al,. 2005. Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft. Cancer Biol Ther 4: 1248-1254.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 1248-1254
-
-
Lee, M.S.1
Yuet-Wa, J.C.2
Kong, S.K.3
-
63
-
-
33750737700
-
New molecular mechanisms of action of camptothecin-type drugs
-
Legarza K, Yang LX,. 2006. New molecular mechanisms of action of camptothecin-type drugs. Anticancer Res 26: 3301-3305.
-
(2006)
Anticancer Res
, vol.26
, pp. 3301-3305
-
-
Legarza, K.1
Yang, L.X.2
-
64
-
-
33750198131
-
Advances in basic and clinical studies of norcantharidin
-
Li B, Ling CQ,. 2002. Advances in basic and clinical studies of norcantharidin. Chin Tradit Herbal Drugs 33: 184-185.
-
(2002)
Chin Tradit Herbal Drugs
, vol.33
, pp. 184-185
-
-
Li, B.1
Ling, C.Q.2
-
65
-
-
11144220863
-
Pseudolaric acid B inhibits angiogenesis and reduces hypoxia-inducible factor 1alpha by promoting proteasome-mediated degradation
-
Li MH, Miao ZH, Tan WF, et al,. 2004. Pseudolaric acid B inhibits angiogenesis and reduces hypoxia-inducible factor 1alpha by promoting proteasome-mediated degradation. Clin Cancer Res 10: 8266-8274.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8266-8274
-
-
Li, M.H.1
Miao, Z.H.2
Tan, W.F.3
-
66
-
-
77649204661
-
Gambogenic acid inhibits proliferation of A549 cells through apoptosis-inducing and cell cycle arresting
-
Li Q, Cheng H, Zhu G, et al,. 2010. Gambogenic acid inhibits proliferation of A549 cells through apoptosis-inducing and cell cycle arresting. Biol Pharm Bull 33: 415-420.
-
(2010)
Biol Pharm Bull
, vol.33
, pp. 415-420
-
-
Li, Q.1
Cheng, H.2
Zhu, G.3
-
67
-
-
67649995348
-
Gambogic acid induces G0/G1 arrest and apoptosis involving inhibition of SRC-3 and inactivation of Akt pathway in K562 leukemia cells
-
Li R, Chen Y, Zeng LL, et al,. 2009. Gambogic acid induces G0/G1 arrest and apoptosis involving inhibition of SRC-3 and inactivation of Akt pathway in K562 leukemia cells. Toxicology 262: 98-105.
-
(2009)
Toxicology
, vol.262
, pp. 98-105
-
-
Li, R.1
Chen, Y.2
Zeng, L.L.3
-
68
-
-
46949091971
-
Improved high-performance liquid chromatographic method for simultaneous determination of 12 cytotoxic caged xanthones in gamboges, a potential anticancer resin from Garcinia hanburyi
-
Li SL, Song JZ, Han QB, Qiao CF, Xu HX,. 2008. Improved high-performance liquid chromatographic method for simultaneous determination of 12 cytotoxic caged xanthones in gamboges, a potential anticancer resin from Garcinia hanburyi. Biomed Chromatogr 22: 637-644.
-
(2008)
Biomed Chromatogr
, vol.22
, pp. 637-644
-
-
Li, S.L.1
Song, J.Z.2
Han, Q.B.3
Qiao, C.F.4
Xu, H.X.5
-
69
-
-
34548083138
-
Solamargine upregulation of Fas, downregulation of HER2, and enhancement of cytotoxicity using epirubicin in NSCLC cells
-
Liang CH, Shiu LY, Chang LC, Sheu HM, Kuo KW,. 2007. Solamargine upregulation of Fas, downregulation of HER2, and enhancement of cytotoxicity using epirubicin in NSCLC cells. Mol Nutr Food Res 51: 999-1005.
-
(2007)
Mol Nutr Food Res
, vol.51
, pp. 999-1005
-
-
Liang, C.H.1
Shiu, L.Y.2
Chang, L.C.3
Sheu, H.M.4
Kuo, K.W.5
-
70
-
-
41649101082
-
Solamargine enhances HER2 expression and increases the susceptibility of human lung cancer H661 and H69 cells to trastuzumab and epirubicin
-
Liang CH, Shiu LY, Chang LC, Sheu HM, Tsai EM, Kuo KW,. 2008. Solamargine enhances HER2 expression and increases the susceptibility of human lung cancer H661 and H69 cells to trastuzumab and epirubicin. Chem Res Toxicol 21: 393-399.
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 393-399
-
-
Liang, C.H.1
Shiu, L.Y.2
Chang, L.C.3
Sheu, H.M.4
Tsai, E.M.5
Kuo, K.W.6
-
71
-
-
56749103201
-
Antiproliferative activity of the total saponin of Solanum lyratum Thunb in HeLa cells by inducing apoptosis
-
Liu HR, Peng XD, He HB, et al,. 2008. Antiproliferative activity of the total saponin of Solanum lyratum Thunb in HeLa cells by inducing apoptosis. Pharmazie 63: 836-842.
-
(2008)
Pharmazie
, vol.63
, pp. 836-842
-
-
Liu, H.R.1
Peng, X.D.2
He, H.B.3
-
72
-
-
0036497131
-
Jolkinolide B induces neuroendocrine differentiation of human prostate LNCaP cancer cell line
-
Liu WK, Ho JC, Qin G, Che CT,. 2002. Jolkinolide B induces neuroendocrine differentiation of human prostate LNCaP cancer cell line. Biochem Pharmacol 63: 951-957.
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 951-957
-
-
Liu, W.K.1
Ho, J.C.2
Qin, G.3
Che, C.T.4
-
73
-
-
34447568292
-
Homoharringtonine induces apoptosis and growth arrest in human myeloma cells
-
Lou YJ, Qian WB, Jin J,. 2007. Homoharringtonine induces apoptosis and growth arrest in human myeloma cells. Leuk Lymphoma 48: 1400-1406.
-
(2007)
Leuk Lymphoma
, vol.48
, pp. 1400-1406
-
-
Lou, Y.J.1
Qian, W.B.2
Jin, J.3
-
74
-
-
0036566529
-
Tetra-arsenic tetra-sulfide for the treatment of acute promyelocytic leukemia: A pilot report
-
Lu DP, Qiu JY, Jiang B, et al,. 2002. Tetra-arsenic tetra-sulfide for the treatment of acute promyelocytic leukemia: a pilot report. Blood 99: 3136-3143.
-
(2002)
Blood
, vol.99
, pp. 3136-3143
-
-
Lu, D.P.1
Qiu, J.Y.2
Jiang, B.3
-
75
-
-
0346451031
-
Current study of APL treatment in China
-
Lu DP, Wang Q,. 2002. Current study of APL treatment in China. Int J Hematol 76 (Suppl 1): 316-318.
-
(2002)
Int J Hematol
, vol.76
, Issue.SUPPL. 1
, pp. 316-318
-
-
Lu, D.P.1
Wang, Q.2
-
76
-
-
34547644483
-
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
-
Lu J, Chew EH, Holmgren A,. 2007a. Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide. Proc Natl Acad Sci USA 104: 12288-12293.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12288-12293
-
-
Lu, J.1
Chew, E.H.2
Holmgren, A.3
-
77
-
-
35348952483
-
Gambogic acid inhibits angiogenesis through suppressing vascular endothelial growth factor-induced tyrosine phosphorylation of KDR/Flk-1
-
Lu N, Yang Y, You QD, et al,. 2007b. Gambogic acid inhibits angiogenesis through suppressing vascular endothelial growth factor-induced tyrosine phosphorylation of KDR/Flk-1. Cancer Lett 258: 80-89.
-
(2007)
Cancer Lett
, vol.258
, pp. 80-89
-
-
Lu, N.1
Yang, Y.2
You, Q.D.3
-
78
-
-
78149461619
-
Periplocin inhibits growth of lung cancer in vitro and in vivo by blocking AKT/ERK signaling pathways
-
Lu ZJ, Zhou Y, Song Q, et al,. 2010. Periplocin inhibits growth of lung cancer in vitro and in vivo by blocking AKT/ERK signaling pathways. Cell Physiol Biochem 26: 609-618.
-
(2010)
Cell Physiol Biochem
, vol.26
, pp. 609-618
-
-
Lu, Z.J.1
Zhou, Y.2
Song, Q.3
-
79
-
-
33748281159
-
Induction of human promyelocytic leukemia HL-60 cell differentiation into monocytes by arsenic sulphide: Involvement of serine/threonine protein phosphatases
-
Luo LY, Huang J, Gou BD, Zhang TL, Wang K,. 2006. Induction of human promyelocytic leukemia HL-60 cell differentiation into monocytes by arsenic sulphide: involvement of serine/threonine protein phosphatases. Leuk Res 30: 1399-1405.
-
(2006)
Leuk Res
, vol.30
, pp. 1399-1405
-
-
Luo, L.Y.1
Huang, J.2
Gou, B.D.3
Zhang, T.L.4
Wang, K.5
-
80
-
-
77955482084
-
Selective inhibition of human leukemia cell growth and induction of cell cycle arrest and apoptosis by pseudolaric acid B
-
Ma G, Chong L, Li XC, Khan IA, Walker LA, Khan SI,. 2010. Selective inhibition of human leukemia cell growth and induction of cell cycle arrest and apoptosis by pseudolaric acid B. J Cancer Res Clin Oncol 136: 1333-1340.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, pp. 1333-1340
-
-
Ma, G.1
Chong, L.2
Li, X.C.3
Khan, I.A.4
Walker, L.A.5
Khan, S.I.6
-
81
-
-
0035879016
-
3) in the orthotopic metastasis model of androgen-independent prostate cancer
-
3) in the orthotopic metastasis model of androgen-independent prostate cancer. Cancer Res 61: 5432-5440.
-
(2001)
Cancer Res
, vol.61
, pp. 5432-5440
-
-
Maeda, H.1
Hori, S.2
Nishitoh, H.3
-
82
-
-
79952761256
-
Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma
-
Man S, Gao W, Zhang Y, et al,. 2011a. Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma. Cancer Biol Ther 11: 592-598.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 592-598
-
-
Man, S.1
Gao, W.2
Zhang, Y.3
-
83
-
-
79955074266
-
Paridis saponins inhibiting carcinoma growth and metastasis in vitro and in vivo
-
Man SL, Gao WY, Zhang YJ, Huang LQ, Liu CX,. 2011b. Paridis saponins inhibiting carcinoma growth and metastasis in vitro and in vivo. Arch Pharm Res 34: 43-50.
-
(2011)
Arch Pharm Res
, vol.34
, pp. 43-50
-
-
Man, S.L.1
Gao, W.Y.2
Zhang, Y.J.3
Huang, L.Q.4
Liu, C.X.5
-
84
-
-
78650805589
-
Separation and purification of effective constituents of Rhizoma Paridis saponins by serum pharmacochemistry guiding
-
Man SL, Gao WY, Zhang YJ, Jin XH, Ma CY, Huang XX,. 2010. Separation and purification of effective constituents of Rhizoma Paridis saponins by serum pharmacochemistry guiding. Lat Am J Pharm 29: 1193-1198.
-
(2010)
Lat Am J Pharm
, vol.29
, pp. 1193-1198
-
-
Man, S.L.1
Gao, W.Y.2
Zhang, Y.J.3
Jin, X.H.4
Ma, C.Y.5
Huang, X.X.6
-
85
-
-
70350564909
-
Antitumor and antimetastatic activities of Rhizoma Paridis saponins
-
Man SL, Gao WY, Zhang YJ, et al,. 2009. Antitumor and antimetastatic activities of Rhizoma Paridis saponins. Steroids 74: 1051-1056.
-
(2009)
Steroids
, vol.74
, pp. 1051-1056
-
-
Man, S.L.1
Gao, W.Y.2
Zhang, Y.J.3
-
86
-
-
65249117412
-
Induction of G2/M arrest by pseudolaric acid B is mediated by activation of the ATM signaling pathway
-
Meng AG, Jiang LL,. 2009. Induction of G2/M arrest by pseudolaric acid B is mediated by activation of the ATM signaling pathway. Acta Pharmacol Sin 30: 442-450.
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 442-450
-
-
Meng, A.G.1
Jiang, L.L.2
-
87
-
-
55049088474
-
Homoharringtonine inhibits the AKT pathway and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells
-
Meng H, Yang C, Jin J, Zhou Y, Qian W,. 2008. Homoharringtonine inhibits the AKT pathway and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells. Leuk Lymphoma 49: 1954-1962.
-
(2008)
Leuk Lymphoma
, vol.49
, pp. 1954-1962
-
-
Meng, H.1
Yang, C.2
Jin, J.3
Zhou, Y.4
Qian, W.5
-
88
-
-
70449376872
-
Pilot study of huachansu in patients with hepatocellular carcinoma, nonsmall-cell lung cancer, or pancreatic cancer
-
Meng Z, Yang P, Shen Y, et al,. 2009. Pilot study of huachansu in patients with hepatocellular carcinoma, nonsmall-cell lung cancer, or pancreatic cancer. Cancer 115: 5309-5318.
-
(2009)
Cancer
, vol.115
, pp. 5309-5318
-
-
Meng, Z.1
Yang, P.2
Shen, Y.3
-
89
-
-
0035834595
-
Transport of 7-ethyl-10-hydroxycamptothecin (SN-38) by breast cancer resistance protein ABCG2 in human lung cancer cells
-
Nakatomi K, Yoshikawa M, Oka M, et al,. 2001. Transport of 7-ethyl-10-hydroxycamptothecin (SN-38) by breast cancer resistance protein ABCG2 in human lung cancer cells. Biochem Biophys Res Commun 288: 827-832.
-
(2001)
Biochem Biophys Res Commun
, vol.288
, pp. 827-832
-
-
Nakatomi, K.1
Yoshikawa, M.2
Oka, M.3
-
90
-
-
34247109045
-
Natural products as sources of new drugs over the last 25 years
-
Newman DJ, Cragg GM,. 2007. Natural products as sources of new drugs over the last 25 years. J Nat Prod 70: 461-477.
-
(2007)
J Nat Prod
, vol.70
, pp. 461-477
-
-
Newman, D.J.1
Cragg, G.M.2
-
91
-
-
0037735274
-
Metabolism of homoharringtonine, a cytotoxic component of the evergreen plant Cephalotaxus harringtonia
-
Ni D, Ho DH, Vijjeswarapu M, Felix E, Rhea PR, Newman RA,. 2003. Metabolism of homoharringtonine, a cytotoxic component of the evergreen plant Cephalotaxus harringtonia. J Exp Ther Oncol 3: 47-52.
-
(2003)
J Exp Ther Oncol
, vol.3
, pp. 47-52
-
-
Ni, D.1
Ho, D.H.2
Vijjeswarapu, M.3
Felix, E.4
Rhea, P.R.5
Newman, R.A.6
-
92
-
-
67349089550
-
Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cells
-
Nie F, Zhang X, Qi Q, et al,. 2009. Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cells. Toxicology 260: 60-67.
-
(2009)
Toxicology
, vol.260
, pp. 60-67
-
-
Nie, F.1
Zhang, X.2
Qi, Q.3
-
93
-
-
77957314681
-
Cytotoxic tirucallane triterpenoids from Melia azedarach fruits
-
Ntalli NG, Cottiglia F, Bueno CA, et al,. 2010. Cytotoxic tirucallane triterpenoids from Melia azedarach fruits. Molecules 15: 5866-5877.
-
(2010)
Molecules
, vol.15
, pp. 5866-5877
-
-
Ntalli, N.G.1
Cottiglia, F.2
Bueno, C.A.3
-
94
-
-
1442334562
-
Camptothecin and Taxol: Historic achievements in natural products research
-
Oberlies NH, Kroll DJ, 2004. Camptothecin and Taxol: historic achievements in natural products research. J Nat Prod 67: 129-135.
-
(2004)
J Nat Prod
, vol.67
, pp. 129-135
-
-
Oberlies, N.H.1
Kroll, D.J.2
-
95
-
-
0029126345
-
Bruceosides D, E, and F, three new cytotoxic quassinoid glucosides from Brucea javanica
-
Ohnishi S, Fukamiya N, Okano M, Tagahara K, Lee KH,. 1995. Bruceosides D, E, and F, three new cytotoxic quassinoid glucosides from Brucea javanica. J Nat Prod 58: 1032-1038.
-
(1995)
J Nat Prod
, vol.58
, pp. 1032-1038
-
-
Ohnishi, S.1
Fukamiya, N.2
Okano, M.3
Tagahara, K.4
Lee, K.H.5
-
96
-
-
18144401713
-
Mechanism of proliferation arrest of embryonic cells of Xenopus by diterpene compounds
-
Okouchi T, Abe T, Araki S, et al,. 2005. Mechanism of proliferation arrest of embryonic cells of Xenopus by diterpene compounds. Bioorg Med Chem 13: 3847-3851.
-
(2005)
Bioorg Med Chem
, vol.13
, pp. 3847-3851
-
-
Okouchi, T.1
Abe, T.2
Araki, S.3
-
97
-
-
39149090383
-
Polyphyllin D induces mitochondrial fragmentation and acts directly on the mitochondria to induce apoptosis in drug-resistant HepG2 cells
-
Ong RC, Lei J, Lee RK, et al,. 2008. Polyphyllin D induces mitochondrial fragmentation and acts directly on the mitochondria to induce apoptosis in drug-resistant HepG2 cells. Cancer Lett 261: 158-164.
-
(2008)
Cancer Lett
, vol.261
, pp. 158-164
-
-
Ong, R.C.1
Lei, J.2
Lee, R.K.3
-
98
-
-
35349029248
-
Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway
-
Pandey MK, Sung B, Ahn KS, Kunnumakkara AB, Chaturvedi MM, Aggarwal BB,. 2007. Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway. Blood 110: 3517-3525.
-
(2007)
Blood
, vol.110
, pp. 3517-3525
-
-
Pandey, M.K.1
Sung, B.2
Ahn, K.S.3
Kunnumakkara, A.B.4
Chaturvedi, M.M.5
Aggarwal, B.B.6
-
99
-
-
0344442301
-
Camptothecin and 9-nitrocamptothecin (9NC) as anti-cancer, anti-HIV and cell-differentiation agents. Development of resistance, enhancement of 9NC-induced activities and combination treatments in cell and animal models
-
Pantazis P, Han Z, Balan K, Wang Y, Wyche JH,. 2003. Camptothecin and 9-nitrocamptothecin (9NC) as anti-cancer, anti-HIV and cell-differentiation agents. Development of resistance, enhancement of 9NC-induced activities and combination treatments in cell and animal models. Anticancer Res 23: 3623-3638.
-
(2003)
Anticancer Res
, vol.23
, pp. 3623-3638
-
-
Pantazis, P.1
Han, Z.2
Balan, K.3
Wang, Y.4
Wyche, J.H.5
-
100
-
-
34247185997
-
Daphnane diterpene esters isolated from flower buds of Daphne genkwa induce apoptosis in human myelocytic HL-60 cells and suppress tumor growth in Lewis lung carcinoma (LLC)-inoculated mouse model
-
Park BY, Min BS, Ahn KS, et al,. 2007. Daphnane diterpene esters isolated from flower buds of Daphne genkwa induce apoptosis in human myelocytic HL-60 cells and suppress tumor growth in Lewis lung carcinoma (LLC)-inoculated mouse model. J Ethnopharmacol 111: 496-503.
-
(2007)
J Ethnopharmacol
, vol.111
, pp. 496-503
-
-
Park, B.Y.1
Min, B.S.2
Ahn, K.S.3
-
101
-
-
0036204047
-
Induction of apoptosis by norcantharidin in human colorectal carcinoma cell lines: Involvement of the CD95 receptor/ligand
-
Peng F, Wei YQ, Tian L, et al,. 2002. Induction of apoptosis by norcantharidin in human colorectal carcinoma cell lines: involvement of the CD95 receptor/ligand. J Cancer Res Clin Oncol 128: 223-230.
-
(2002)
J Cancer Res Clin Oncol
, vol.128
, pp. 223-230
-
-
Peng, F.1
Wei, Y.Q.2
Tian, L.3
-
102
-
-
33744969575
-
Anticancer effects of low-dose 10-hydroxycamptothecin in human colon cancer
-
Ping YH, Lee HC, Lee JY, et al,. 2006. Anticancer effects of low-dose 10-hydroxycamptothecin in human colon cancer. Oncol Rep 15: 1273-1279.
-
(2006)
Oncol Rep
, vol.15
, pp. 1273-1279
-
-
Ping, Y.H.1
Lee, H.C.2
Lee, J.Y.3
-
103
-
-
46049119027
-
Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response
-
Protiva P, Hopkins ME, Baggett S, et al,. 2008. Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response. Int J Cancer 123: 687-694.
-
(2008)
Int J Cancer
, vol.123
, pp. 687-694
-
-
Protiva, P.1
Hopkins, M.E.2
Baggett, S.3
-
104
-
-
80052748810
-
The budding yeast 'Saccharomyces cerevisiae' as a drug discovery tool to identify plant-derived natural products with anti-proliferative properties
-
in press. DOI: 10.1093/ecam/nep069
-
Qaddouri B, Guaadaoui A, Bellirou A, et al,. in press. The budding yeast 'Saccharomyces cerevisiae' as a drug discovery tool to identify plant-derived natural products with anti-proliferative properties. Evid Based Complement Alternat Med. DOI: 10.1093/ecam/nep069
-
Evid Based Complement Alternat Med
-
-
Qaddouri, B.1
Guaadaoui, A.2
Bellirou, A.3
-
105
-
-
38949176773
-
Inhibition of glioblastoma cgrowth and angiogenesis by gambogic acid: An in vitro and in vivo study
-
Qiang L, Yang Y, You QD, et al,. 2008. Inhibition of glioblastoma cgrowth and angiogenesis by gambogic acid: an in vitro and in vivo study. Biochem Pharmacol 75: 1083-1092.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 1083-1092
-
-
Qiang, L.1
Yang, Y.2
You, Q.D.3
-
106
-
-
34748925888
-
Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain
-
Qin Y, Meng L, Hu C, et al,. 2007. Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain. Mol Cancer Ther 6: 2429-2440.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2429-2440
-
-
Qin, Y.1
Meng, L.2
Hu, C.3
-
107
-
-
70350023622
-
Arsenic trioxide inhibits the growth of human lung cancer cell lines via cell cycle arrest and induction of apoptosis at both normoxia and hypoxia
-
Qu GP, Xiu QY, Li B, Liu YA, Zhang LZ,. 2009. Arsenic trioxide inhibits the growth of human lung cancer cell lines via cell cycle arrest and induction of apoptosis at both normoxia and hypoxia. Toxicol Ind Health 25: 505-515.
-
(2009)
Toxicol Ind Health
, vol.25
, pp. 505-515
-
-
Qu, G.P.1
Xiu, Q.Y.2
Li, B.3
Liu, Y.A.4
Zhang, L.Z.5
-
108
-
-
34547807709
-
Molecular biology of cantharidin in cancer cells
-
Rauh R, Kahl S, Boechzelt H, Bauer R, Kaina B, Efferth T,. 2007. Molecular biology of cantharidin in cancer cells. Chin Med 2: 8.
-
(2007)
Chin Med
, vol.2
, pp. 8
-
-
Rauh, R.1
Kahl, S.2
Boechzelt, H.3
Bauer, R.4
Kaina, B.5
Efferth, T.6
-
109
-
-
33847784480
-
Cytotoxic and anti-HIV-1 caged xanthones from the resin and fruits of Garcinia hanburyi
-
Reutrakul V, Anantachoke N, Pohmakotr M, et al,. 2007. Cytotoxic and anti-HIV-1 caged xanthones from the resin and fruits of Garcinia hanburyi. Planta Med 73: 33-40.
-
(2007)
Planta Med
, vol.73
, pp. 33-40
-
-
Reutrakul, V.1
Anantachoke, N.2
Pohmakotr, M.3
-
110
-
-
33845431356
-
Safety of traditional arab herbal medicine
-
Saad B, Azaizeh H, Abu-Hijleh G, Said O,. 2006. Safety of traditional arab herbal medicine. Evid Based Complement Alternat Med 3: 433-439.
-
(2006)
Evid Based Complement Alternat Med
, vol.3
, pp. 433-439
-
-
Saad, B.1
Azaizeh, H.2
Abu-Hijleh, G.3
Said, O.4
-
111
-
-
34248208151
-
Biological effects of toosendanin, a triterpenoid extracted from Chinese traditional medicine
-
Shi YL, Li MF,. 2007. Biological effects of toosendanin, a triterpenoid extracted from Chinese traditional medicine. Prog Neurobiol 82: 1-10.
-
(2007)
Prog Neurobiol
, vol.82
, pp. 1-10
-
-
Shi, Y.L.1
Li, M.F.2
-
112
-
-
49749104260
-
Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): Induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways
-
Siu FM, Ma DL, Cheung YW, et al,. 2008. Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways. Proteomics 8: 3105-3117.
-
(2008)
Proteomics
, vol.8
, pp. 3105-3117
-
-
Siu, F.M.1
Ma, D.L.2
Cheung, Y.W.3
-
113
-
-
34250331674
-
Antiproliferative cardenolides from Periploca graeca
-
Spera D, Siciliano T, De Tommasi N, Braca A, Vessieres A,. 2007. Antiproliferative cardenolides from Periploca graeca. Planta Med 73: 384-387.
-
(2007)
Planta Med
, vol.73
, pp. 384-387
-
-
Spera, D.1
Siciliano, T.2
De Tommasi, N.3
Braca, A.4
Vessieres, A.5
-
114
-
-
59849087975
-
Involvement of caspases and apoptosis-inducing factor in bufotalin-induced apoptosis of Hep 3B cells
-
Su CL, Lin TY, Lin CN, Won SJ,. 2009. Involvement of caspases and apoptosis-inducing factor in bufotalin-induced apoptosis of Hep 3B cells. J Agric Food Chem 57: 55-61.
-
(2009)
J Agric Food Chem
, vol.57
, pp. 55-61
-
-
Su, C.L.1
Lin, T.Y.2
Lin, C.N.3
Won, S.J.4
-
115
-
-
77956180671
-
A lysosomal-mitochondrial death pathway is induced by solamargine in human K562 leukemia cells
-
Sun L, Zhao Y, Li X, Yuan H, Cheng A, Lou H,. 2010. A lysosomal-mitochondrial death pathway is induced by solamargine in human K562 leukemia cells. Toxicol In Vitro 24: 1504-1511.
-
(2010)
Toxicol in Vitro
, vol.24
, pp. 1504-1511
-
-
Sun, L.1
Zhao, Y.2
Li, X.3
Yuan, H.4
Cheng, A.5
Lou, H.6
-
116
-
-
0033168328
-
Limonoids from fruit of Melia toosendan and their cytotoxic activity
-
Tada K, Takido M, Kitanaka S,. 1999. Limonoids from fruit of Melia toosendan and their cytotoxic activity. Phytochemistry 51: 787-791.
-
(1999)
Phytochemistry
, vol.51
, pp. 787-791
-
-
Tada, K.1
Takido, M.2
Kitanaka, S.3
-
117
-
-
20444504721
-
Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting i kappa B alpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion
-
Takada Y, Kobayashi Y, Aggarwal BB,. 2005. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting I kappa B alpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion. J Biol Chem 280: 17203-17212.
-
(2005)
J Biol Chem
, vol.280
, pp. 17203-17212
-
-
Takada, Y.1
Kobayashi, Y.2
Aggarwal, B.B.3
-
118
-
-
0036545581
-
Protein kinase C activation by iridal type triterpenoids
-
Takahashi K, Suzuki S, Hano Y, Nomura T,. 2002. Protein kinase C activation by iridal type triterpenoids. Biol Pharm Bull 25: 432-436.
-
(2002)
Biol Pharm Bull
, vol.25
, pp. 432-436
-
-
Takahashi, K.1
Suzuki, S.2
Hano, Y.3
Nomura, T.4
-
119
-
-
4544375253
-
Pseudolarix acid B inhibits angiogenesis by antagonizing the vascular endothelial growth factor-mediated anti-apoptotic effect
-
Tan WF, Zhang XW, Li MH, et al,. 2004. Pseudolarix acid B inhibits angiogenesis by antagonizing the vascular endothelial growth factor-mediated anti-apoptotic effect. Eur J Pharmacol 499: 219-228.
-
(2004)
Eur J Pharmacol
, vol.499
, pp. 219-228
-
-
Tan, W.F.1
Zhang, X.W.2
Li, M.H.3
-
120
-
-
0034130822
-
Prevention of colonic aberrant crypt foci by dietary feeding of garcinol in male F344 rats
-
Tanaka T, Kohno H, Shimada R, et al,. 2000. Prevention of colonic aberrant crypt foci by dietary feeding of garcinol in male F344 rats. Carcinogenesis 21: 1183-1189.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1183-1189
-
-
Tanaka, T.1
Kohno, H.2
Shimada, R.3
-
121
-
-
3543077491
-
Involvement of cytochrome c release and caspase activation in toosendanin-induced PC12 cell apoptosis
-
Tang MZ, Wang ZF, Shi YL,. 2004. Involvement of cytochrome c release and caspase activation in toosendanin-induced PC12 cell apoptosis. Toxicology 201: 31-38.
-
(2004)
Toxicology
, vol.201
, pp. 31-38
-
-
Tang, M.Z.1
Wang, Z.F.2
Shi, Y.L.3
-
122
-
-
66749137756
-
Dauricine inhibits insulin-like growth factor-I-induced hypoxia inducible factor 1alpha protein accumulation and vascular endothelial growth factor expression in human breast cancer cells
-
Tang XD, Zhou X, Zhou KY,. 2009. Dauricine inhibits insulin-like growth factor-I-induced hypoxia inducible factor 1alpha protein accumulation and vascular endothelial growth factor expression in human breast cancer cells. Acta Pharmacol Sin 30: 605-616.
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 605-616
-
-
Tang, X.D.1
Zhou, X.2
Zhou, K.Y.3
-
123
-
-
60549086634
-
Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi
-
Tao SJ, Guan SH, Wang W, et al,. 2009. Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi. J Nat Prod 72: 117-124.
-
(2009)
J Nat Prod
, vol.72
, pp. 117-124
-
-
Tao, S.J.1
Guan, S.H.2
Wang, W.3
-
124
-
-
51649110473
-
Homoharringtonine affects the JAK2-STAT5 signal pathway through alteration of protein tyrosine kinase phosphorylation in acute myeloid leukemia cells
-
Tong H, Ren Y, Zhang F, Jin J,. 2008. Homoharringtonine affects the JAK2-STAT5 signal pathway through alteration of protein tyrosine kinase phosphorylation in acute myeloid leukemia cells. Eur J Haematol 81: 259-266.
-
(2008)
Eur J Haematol
, vol.81
, pp. 259-266
-
-
Tong, H.1
Ren, Y.2
Zhang, F.3
Jin, J.4
-
125
-
-
33645102444
-
Pseudolarix acid B, a new tubulin-binding agent, inhibits angiogenesis by interacting with a novel binding site on tubulin
-
Tong YG, Zhang XW, Geng MY, et al,. 2006. Pseudolarix acid B, a new tubulin-binding agent, inhibits angiogenesis by interacting with a novel binding site on tubulin. Mol Pharmacol 69: 1226-1233.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 1226-1233
-
-
Tong, Y.G.1
Zhang, X.W.2
Geng, M.Y.3
-
126
-
-
0036569629
-
Expression of p53-family members and associated target molecules in breast cancer cell lines in response to vincristine treatment
-
Vayssade M, Faridoni-Laurens L, Benard J, Ahomadegbe JC,. 2002. Expression of p53-family members and associated target molecules in breast cancer cell lines in response to vincristine treatment. Biochem Pharmacol 63: 1609-1617.
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 1609-1617
-
-
Vayssade, M.1
Faridoni-Laurens, L.2
Benard, J.3
Ahomadegbe, J.C.4
-
127
-
-
0034622104
-
Cytotoxic effects of cantharidin on the growth of normal and carcinoma cells
-
Wang CC, Wu CH, Hsieh KJ, Yen KY, Yang LL,. 2000. Cytotoxic effects of cantharidin on the growth of normal and carcinoma cells. Toxicology 147: 77-87.
-
(2000)
Toxicology
, vol.147
, pp. 77-87
-
-
Wang, C.C.1
Wu, C.H.2
Hsieh, K.J.3
Yen, K.Y.4
Yang, L.L.5
-
128
-
-
78650141070
-
Diterpenoids from the roots of Euphorbia fischeriana
-
Wang HB, Chu WJ, Wang Y, et al,. 2010. Diterpenoids from the roots of Euphorbia fischeriana. J Asian Nat Prod Res 12: 1038-1043.
-
(2010)
J Asian Nat Prod Res
, vol.12
, pp. 1038-1043
-
-
Wang, H.B.1
Chu, W.J.2
Wang, Y.3
-
129
-
-
57149114137
-
Two novel triterpenoids with antiproliferative and apoptotic activities in human leukemia cells isolated from the resin of Garcinia hanburyi
-
Wang LL, Li ZL, Song DD, et al,. 2008a. Two novel triterpenoids with antiproliferative and apoptotic activities in human leukemia cells isolated from the resin of Garcinia hanburyi. Planta Med 74: 1735-1740.
-
(2008)
Planta Med
, vol.74
, pp. 1735-1740
-
-
Wang, L.L.1
Li, Z.L.2
Song, D.D.3
-
130
-
-
71249157722
-
Association of oxidative stress with realgar-induced differentiation in human leukemia HL-60 cells
-
Wang LW, Shi YL, Wang N, et al,. 2009a. Association of oxidative stress with realgar-induced differentiation in human leukemia HL-60 cells. Chemotherapy 55: 460-467.
-
(2009)
Chemotherapy
, vol.55
, pp. 460-467
-
-
Wang, L.W.1
Shi, Y.L.2
Wang, N.3
-
131
-
-
17444380922
-
Anti-inflammatory activity of new guaiane type sesquiterpene from Wikstroemia indica
-
Wang LY, Unehara T, Kitanaka S,. 2005. Anti-inflammatory activity of new guaiane type sesquiterpene from Wikstroemia indica. Chem Pharm Bull(Tokyo) 53: 137-139.
-
(2005)
Chem Pharm Bull(Tokyo)
, vol.53
, pp. 137-139
-
-
Wang, L.Y.1
Unehara, T.2
Kitanaka, S.3
-
132
-
-
0038188709
-
Euphane and tirucallane triterpenes from the roots of Euphorbia kansui and their in vitro effects on the cell division of Xenopus
-
Wang LY, Wang NL, Yao XS, Miyata S, Kitanaka S,. 2003. Euphane and tirucallane triterpenes from the roots of Euphorbia kansui and their in vitro effects on the cell division of Xenopus. J Nat Prod 66: 630-633.
-
(2003)
J Nat Prod
, vol.66
, pp. 630-633
-
-
Wang, L.Y.1
Wang, N.L.2
Yao, X.S.3
Miyata, S.4
Kitanaka, S.5
-
133
-
-
33746347660
-
Gene expression profile of multiple myeloma cell line treated by realgar
-
Wang MC, Liu SX, Liu PB,. 2006. Gene expression profile of multiple myeloma cell line treated by realgar. J Exp Clin Cancer Res 25: 243-249.
-
(2006)
J Exp Clin Cancer Res
, vol.25
, pp. 243-249
-
-
Wang, M.C.1
Liu, S.X.2
Liu, P.B.3
-
134
-
-
56149102360
-
Realgar-induced differentiation is associated with MAPK pathways in HL-60 cells
-
Wang N, Wang LW, Gou BD, Zhang TL, Wang K,. 2008b. Realgar-induced differentiation is associated with MAPK pathways in HL-60 cells. Cell Biol Int 32: 1497-1505.
-
(2008)
Cell Biol Int
, vol.32
, pp. 1497-1505
-
-
Wang, N.1
Wang, L.W.2
Gou, B.D.3
Zhang, T.L.4
Wang, K.5
-
135
-
-
60349092524
-
Proteomic identification of molecular targets of gambogic acid: Role of stathmin in hepatocellular carcinoma
-
Wang X, Chen Y, Han QB, et al,. 2009b. Proteomic identification of molecular targets of gambogic acid: role of stathmin in hepatocellular carcinoma. Proteomics 9: 242-253.
-
(2009)
Proteomics
, vol.9
, pp. 242-253
-
-
Wang, X.1
Chen, Y.2
Han, Q.B.3
-
136
-
-
70349754439
-
17-Hydroxy-jolkinolide B inhibits signal transducers and activators of transcription 3 signaling by covalently cross-linking Janus kinases and induces apoptosis of human cancer cells
-
Wang Y, Ma X, Yan S, et al,. 2009c. 17-Hydroxy-jolkinolide B inhibits signal transducers and activators of transcription 3 signaling by covalently cross-linking Janus kinases and induces apoptosis of human cancer cells. Cancer Res 69: 7302-7310.
-
(2009)
Cancer Res
, vol.69
, pp. 7302-7310
-
-
Wang, Y.1
Ma, X.2
Yan, S.3
-
137
-
-
0002963496
-
Arsenic compounds as anticancer agents
-
Wang ZY,. 2001. Arsenic compounds as anticancer agents. Cancer Chemother Pharmacol 48 (Suppl 1): S72-S76.
-
(2001)
Cancer Chemother Pharmacol
, vol.48
, Issue.SUPPL. 1
-
-
Wang, Z.Y.1
-
138
-
-
23844557173
-
Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo
-
Wong VK, Chiu P, Chung SS, et al,. 2005. Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo. Clin Cancer Res 11: 6002-6011.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6002-6011
-
-
Wong, V.K.1
Chiu, P.2
Chung, S.S.3
-
139
-
-
33747809671
-
Evaluation of the in vitro activity and in vivo bioavailability of realgar nanoparticles prepared by cryo-grinding
-
Wu JZ, Ho PC,. 2006. Evaluation of the in vitro activity and in vivo bioavailability of realgar nanoparticles prepared by cryo-grinding. Eur J Pharm Sci 29: 35-44.
-
(2006)
Eur J Pharm Sci
, vol.29
, pp. 35-44
-
-
Wu, J.Z.1
Ho, P.C.2
-
140
-
-
77956020997
-
Milk fat globule EGF factor 8 attenuates sepsis-induced apoptosis and organ injury in alcohol-intoxicated rats
-
Wu R, Chaung WW, Zhou M, et al,. 2010. Milk fat globule EGF factor 8 attenuates sepsis-induced apoptosis and organ injury in alcohol-intoxicated rats. Alcohol Clin Exp Res 34: 1625-1633.
-
(2010)
Alcohol Clin Exp Res
, vol.34
, pp. 1625-1633
-
-
Wu, R.1
Chaung, W.W.2
Zhou, M.3
-
141
-
-
64849110212
-
GA3, a new gambogic acid derivative, exhibits potent antitumor activities in vitro via apoptosis-involved mechanisms
-
Xie H, Qin YX, Zhou YL, et al,. 2009. GA3, a new gambogic acid derivative, exhibits potent antitumor activities in vitro via apoptosis-involved mechanisms. Acta Pharmacol Sin 30: 346-354.
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 346-354
-
-
Xie, H.1
Qin, Y.X.2
Zhou, Y.L.3
-
142
-
-
61949442809
-
A review on hemisynthesis, biosynthesis, biological activities, mode of action, and structure-activity relationship of podophyllotoxins: 2003-2007
-
Xu H, Lv M, Tian X,. 2009. A review on hemisynthesis, biosynthesis, biological activities, mode of action, and structure-activity relationship of podophyllotoxins: 2003-2007. Curr Med Chem 16: 327-349.
-
(2009)
Curr Med Chem
, vol.16
, pp. 327-349
-
-
Xu, H.1
Lv, M.2
Tian, X.3
-
143
-
-
65549154851
-
In vitro and in vivo anticancer activity of steroid saponins of Paris polyphylla var. yunnanensis
-
Yan LL, Zhang YJ, Gao WY, Man SL, Wang Y,. 2009. In vitro and in vivo anticancer activity of steroid saponins of Paris polyphylla var. yunnanensis. Exp Oncol 31: 27-32.
-
(2009)
Exp Oncol
, vol.31
, pp. 27-32
-
-
Yan, L.L.1
Zhang, Y.J.2
Gao, W.Y.3
Man, S.L.4
Wang, Y.5
-
144
-
-
33646406554
-
Celastrol, a triterpene extracted from the Chinese 'Thunder of God Vine', is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice
-
Yang H, Chen D, Cui QC, Yuan X, Dou QP,. 2006. Celastrol, a triterpene extracted from the Chinese 'Thunder of God Vine', is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice. Cancer Res 66: 4758-4765.
-
(2006)
Cancer Res
, vol.66
, pp. 4758-4765
-
-
Yang, H.1
Chen, D.2
Cui, Q.C.3
Yuan, X.4
Dou, Q.P.5
-
145
-
-
0141576565
-
Triptolide inhibits the growth and metastasis of solid tumors
-
Yang S, Chen J, Guo Z, et al,. 2003. Triptolide inhibits the growth and metastasis of solid tumors. Mol Cancer Ther 2: 65-72.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 65-72
-
-
Yang, S.1
Chen, J.2
Guo, Z.3
-
146
-
-
34548679604
-
Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes
-
Yang Y, Yang L, You QD, et al,. 2007. Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes. Cancer Lett 256: 259-266.
-
(2007)
Cancer Lett
, vol.256
, pp. 259-266
-
-
Yang, Y.1
Yang, L.2
You, Q.D.3
-
147
-
-
65849240674
-
Increased expression of HSP27 linked to vincristine resistance in human gastric cancer cell line
-
Yang YX, Sun XF, Cheng AL, et al,. 2009a. Increased expression of HSP27 linked to vincristine resistance in human gastric cancer cell line. J Cancer Res Clin Oncol 135: 181-189.
-
(2009)
J Cancer Res Clin Oncol
, vol.135
, pp. 181-189
-
-
Yang, Y.X.1
Sun, X.F.2
Cheng, A.L.3
-
148
-
-
77956501287
-
Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells
-
Yang Z, Li C, Wang X, et al,. 2010. Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells. J Cell Physiol 225: 266-275.
-
(2010)
J Cell Physiol
, vol.225
, pp. 266-275
-
-
Yang, Z.1
Li, C.2
Wang, X.3
-
149
-
-
14844346999
-
Fluorophore-appended steroidal saponin (dioscin and polyphyllin D) derivatives
-
Yang Z, Wong EL, Shum TY, Che CM, Hui Y,. 2005. Fluorophore-appended steroidal saponin (dioscin and polyphyllin D) derivatives. Org Lett 7: 669-672.
-
(2005)
Org Lett
, vol.7
, pp. 669-672
-
-
Yang, Z.1
Wong, E.L.2
Shum, T.Y.3
Che, C.M.4
Hui, Y.5
-
150
-
-
67650156103
-
Antiproliferation and apoptosis induced by evodiamine in human colorectal carcinoma cells (COLO-205)
-
Yang ZG, Chen AQ, Liu B,. 2009b. Antiproliferation and apoptosis induced by evodiamine in human colorectal carcinoma cells (COLO-205). Chem Biodivers 6: 924-933.
-
(2009)
Chem Biodivers
, vol.6
, pp. 924-933
-
-
Yang, Z.G.1
Chen, A.Q.2
Liu, B.3
-
151
-
-
0034085563
-
Inhibitory effect of euphol, a triterpene alcohol from the roots of Euphorbia kansui, on tumour promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin
-
Yasukawa K, Akihisa T, Yoshida ZY, Takido M,. 2000. Inhibitory effect of euphol, a triterpene alcohol from the roots of Euphorbia kansui, on tumour promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. J Pharm Pharmacol 52: 119-124.
-
(2000)
J Pharm Pharmacol
, vol.52
, pp. 119-124
-
-
Yasukawa, K.1
Akihisa, T.2
Yoshida, Z.Y.3
Takido, M.4
-
152
-
-
65549139742
-
A standardized extract of Ginkgo biloba suppresses doxorubicin-induced oxidative stress and p53-mediated mitochondrial apoptosis in rat testes
-
Yeh YC, Liu TJ, Wang LC, et al,. 2009. A standardized extract of Ginkgo biloba suppresses doxorubicin-induced oxidative stress and p53-mediated mitochondrial apoptosis in rat testes. Br J Pharmacol 156: 48-61.
-
(2009)
Br J Pharmacol
, vol.156
, pp. 48-61
-
-
Yeh, Y.C.1
Liu, T.J.2
Wang, L.C.3
-
153
-
-
40949101023
-
Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling
-
Yi T, Yi Z, Cho SG, et al,. 2008. Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling. Cancer Res 68: 1843-1850.
-
(2008)
Cancer Res
, vol.68
, pp. 1843-1850
-
-
Yi, T.1
Yi, Z.2
Cho, S.G.3
-
154
-
-
48449091482
-
Quality estimation on material medica of Rhizoma Paridis from Sichuan & Yunnan province
-
Yin HX, Xue D, Wu M, Chen Y, Chen C, Zhang H,. 2007. Quality estimation on material medica of Rhizoma Paridis from Sichuan & Yunnan province. Zhong Yao Cai 30: 771-774.
-
(2007)
Zhong Yao Cai
, vol.30
, pp. 771-774
-
-
Yin, H.X.1
Xue, D.2
Wu, M.3
Chen, Y.4
Chen, C.5
Zhang, H.6
-
155
-
-
10344225622
-
Combined effects of As4S4 and imatinib on chronic myeloid leukemia cells and BCR-ABL oncoprotein
-
Yin T, Wu YL, Sun HP, et al,. 2004. Combined effects of As4S4 and imatinib on chronic myeloid leukemia cells and BCR-ABL oncoprotein. Blood 104: 4219-4225.
-
(2004)
Blood
, vol.104
, pp. 4219-4225
-
-
Yin, T.1
Wu, Y.L.2
Sun, H.P.3
-
156
-
-
67651085417
-
Toxicity studies on Secretio Bufonis: A traditional supplement in Asia
-
Yoo WS, Kim J, Lee YW, Yoon DH, Cho CK, Yoo HS,. 2009. Toxicity studies on Secretio Bufonis: a traditional supplement in Asia. J Acupunct Meridian Stud 2: 159-164.
-
(2009)
J Acupunct Meridian Stud
, vol.2
, pp. 159-164
-
-
Yoo, W.S.1
Kim, J.2
Lee, Y.W.3
Yoon, D.H.4
Cho, C.K.5
Yoo, H.S.6
-
157
-
-
75649088161
-
Analysis of inhibition of topoisomerase IIalpha and cancer cell proliferation by ingenolEZ
-
Yoshida C, Hishiyama K, Miyazaki K, et al,. 2010. Analysis of inhibition of topoisomerase IIalpha and cancer cell proliferation by ingenolEZ. Cancer Sci 101: 374-378.
-
(2010)
Cancer Sci
, vol.101
, pp. 374-378
-
-
Yoshida, C.1
Hishiyama, K.2
Miyazaki, K.3
-
158
-
-
20144382617
-
Dietary garcinol inhibits 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in rats
-
Yoshida K, Tanaka T, Hirose Y, et al,. 2005. Dietary garcinol inhibits 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in rats. Cancer Lett 221: 29-39.
-
(2005)
Cancer Lett
, vol.221
, pp. 29-39
-
-
Yoshida, K.1
Tanaka, T.2
Hirose, Y.3
-
159
-
-
0029946865
-
Antitumor activity of daphnane-type diterpene gnidimacrin isolated from Stellera chamaejasme L
-
Yoshida M, Feng W, Saijo N, Ikekawa T,. 1996. Antitumor activity of daphnane-type diterpene gnidimacrin isolated from Stellera chamaejasme L. Int J Cancer 66: 268-273.
-
(1996)
Int J Cancer
, vol.66
, pp. 268-273
-
-
Yoshida, M.1
Feng, W.2
Saijo, N.3
Ikekawa, T.4
-
160
-
-
0031835782
-
Mechanism of antitumor action of PKC activator, gnidimacrin
-
Yoshida M, Yokokura H, Hidaka H, Ikekawa T, Saijo N,. 1998. Mechanism of antitumor action of PKC activator, gnidimacrin. Int J Cancer 77: 243-250.
-
(1998)
Int J Cancer
, vol.77
, pp. 243-250
-
-
Yoshida, M.1
Yokokura, H.2
Hidaka, H.3
Ikekawa, T.4
Saijo, N.5
-
161
-
-
36348961237
-
Cytotoxic lignans from the stem bark of Magnolia officinalis
-
Youn UJ, Chen QC, Jin WJ, et al,. 2007. Cytotoxic lignans from the stem bark of Magnolia officinalis. J Nat Prod 70: 1687-1689.
-
(2007)
J Nat Prod
, vol.70
, pp. 1687-1689
-
-
Youn, U.J.1
Chen, Q.C.2
Jin, W.J.3
-
162
-
-
34047133853
-
Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells
-
Yu J, Guo QL, You QD, et al,. 2007. Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells. Carcinogenesis 28: 632-638.
-
(2007)
Carcinogenesis
, vol.28
, pp. 632-638
-
-
Yu, J.1
Guo, Q.L.2
You, Q.D.3
-
163
-
-
51349130575
-
Protein tyrosine kinase, JNK, and ERK involvement in pseudolaric acid B-induced apoptosis of human breast cancer MCF-7 cells
-
Yu JH, Wang HJ, Li XR, Tashiro S, Onodera S, Ikejima T,. 2008. Protein tyrosine kinase, JNK, and ERK involvement in pseudolaric acid B-induced apoptosis of human breast cancer MCF-7 cells. Acta Pharmacol Sin 29: 1069-1076.
-
(2008)
Acta Pharmacol Sin
, vol.29
, pp. 1069-1076
-
-
Yu, J.H.1
Wang, H.J.2
Li, X.R.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
164
-
-
70349984537
-
XMT-1001, a novel polymeric camptothecin pro-drug in clinical development for patients with advanced cancer
-
Yurkovetskiy AV, Fram RJ,. 2009. XMT-1001, a novel polymeric camptothecin pro-drug in clinical development for patients with advanced cancer. Adv Drug Deliv Rev 61: 1193-1202.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 1193-1202
-
-
Yurkovetskiy, A.V.1
Fram, R.J.2
-
165
-
-
11844289554
-
Novel diterpenoids with potent inhibitory activity against endothelium cell HMEC and cytotoxic activities from a well-known TCM plant Daphne genkwa
-
Zhan ZJ, Fan CQ, Ding J, Yue JM,. 2005. Novel diterpenoids with potent inhibitory activity against endothelium cell HMEC and cytotoxic activities from a well-known TCM plant Daphne genkwa. Bioorg Med Chem 13: 645-655.
-
(2005)
Bioorg Med Chem
, vol.13
, pp. 645-655
-
-
Zhan, Z.J.1
Fan, C.Q.2
Ding, J.3
Yue, J.M.4
-
166
-
-
31544459540
-
Growth inhibition and apoptosis-induced effect on human cancer cells of toosendanin, a triterpenoid derivative from Chinese traditional medicine
-
Zhang B, Wang ZF, Tang MZ, Shi YL,. 2005. Growth inhibition and apoptosis-induced effect on human cancer cells of toosendanin, a triterpenoid derivative from Chinese traditional medicine. Invest New Drugs 23: 547-553.
-
(2005)
Invest New Drugs
, vol.23
, pp. 547-553
-
-
Zhang, B.1
Wang, Z.F.2
Tang, M.Z.3
Shi, Y.L.4
-
167
-
-
0347320714
-
Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay
-
Zhang HZ, Kasibhatla S, Wang Y, et al,. 2004a. Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay. Bioorg Med Chem 12: 309-317.
-
(2004)
Bioorg Med Chem
, vol.12
, pp. 309-317
-
-
Zhang, H.Z.1
Kasibhatla, S.2
Wang, Y.3
-
168
-
-
33646064109
-
Preparation of yuanhuacine and relative daphne diterpene esters from Daphne genkwa and structure-activity relationship of potent inhibitory activity against DNA topoisomerase i
-
Zhang S, Li X, Zhang F, Yang P, Gao X, Song Q,. 2006. Preparation of yuanhuacine and relative daphne diterpene esters from Daphne genkwa and structure-activity relationship of potent inhibitory activity against DNA topoisomerase I. Bioorg Med Chem 14: 3888-3895.
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 3888-3895
-
-
Zhang, S.1
Li, X.2
Zhang, F.3
Yang, P.4
Gao, X.5
Song, Q.6
-
169
-
-
34548504320
-
Simultaneous characterization of isoflavonoids and astragalosides in two Astragalus species by high-performance liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry
-
Zhang X, Xiao HB, Xue XY, Sun YG, Liang XM,. 2007. Simultaneous characterization of isoflavonoids and astragalosides in two Astragalus species by high-performance liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry. J Sep Sci 30: 2059-2069.
-
(2007)
J Sep Sci
, vol.30
, pp. 2059-2069
-
-
Zhang, X.1
Xiao, H.B.2
Xue, X.Y.3
Sun, Y.G.4
Liang, X.M.5
-
170
-
-
0032864365
-
Apoptosis induction and cell cycle perturbation in human hepatoma hep G2 cells by 10-hydroxycamptothecin
-
Zhang XW, Qing C, Xu B,. 1999. Apoptosis induction and cell cycle perturbation in human hepatoma hep G2 cells by 10-hydroxycamptothecin. Anticancer Drugs 10: 569-576.
-
(1999)
Anticancer Drugs
, vol.10
, pp. 569-576
-
-
Zhang, X.W.1
Qing, C.2
Xu, B.3
-
171
-
-
18244368114
-
Intracellular regulation of evodiamine-induced A375-S2 cell death
-
Zhang Y, Wu LJ, Tashiro S, Onodera S, Ikejima T,. 2003. Intracellular regulation of evodiamine-induced A375-S2 cell death. Biol Pharm Bull 26: 1543-1547.
-
(2003)
Biol Pharm Bull
, vol.26
, pp. 1543-1547
-
-
Zhang, Y.1
Wu, L.J.2
Tashiro, S.3
Onodera, S.4
Ikejima, T.5
-
172
-
-
0442278366
-
Atypical apoptosis in L929 cells induced by evodiamine isolated from Evodia rutaecarpa
-
Zhang Y, Zhang QH, Wu LJ, Tashiro S, Onodera S, Ikejima T,. 2004b. Atypical apoptosis in L929 cells induced by evodiamine isolated from Evodia rutaecarpa. J Asian Nat Prod Res 6: 19-27.
-
(2004)
J Asian Nat Prod Res
, vol.6
, pp. 19-27
-
-
Zhang, Y.1
Zhang, Q.H.2
Wu, L.J.3
Tashiro, S.4
Onodera, S.5
Ikejima, T.6
-
173
-
-
47549099788
-
Inhibition of alpha(4) integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acid
-
Zhao J, Qi Q, Yang Y, et al,. 2008. Inhibition of alpha(4) integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acid. Eur J Pharmacol 589: 127-131.
-
(2008)
Eur J Pharmacol
, vol.589
, pp. 127-131
-
-
Zhao, J.1
Qi, Q.2
Yang, Y.3
-
174
-
-
77954381626
-
Periplocin from Cortex periplocae inhibits cell growth and down-regulates survivin and c-myc expression in colon cancer in vitro and in vivo via beta-catenin/TCF signaling
-
Zhao L, Shan B, Du Y, Wang M, Liu L, Ren FZ,. 2010. Periplocin from Cortex periplocae inhibits cell growth and down-regulates survivin and c-myc expression in colon cancer in vitro and in vivo via beta-catenin/TCF signaling. Oncol Rep 24: 375-383.
-
(2010)
Oncol Rep
, vol.24
, pp. 375-383
-
-
Zhao, L.1
Shan, B.2
Du, Y.3
Wang, M.4
Liu, L.5
Ren, F.Z.6
-
175
-
-
84865976745
-
Effect of size and processing method on the cytotoxicity of realgar nanoparticles in cancer cell lines
-
Zhao W, Lu X, Yuan Y, et al,. 2011. Effect of size and processing method on the cytotoxicity of realgar nanoparticles in cancer cell lines. Int J Nanomedicine 6: 1569-1577.
-
(2011)
Int J Nanomedicine
, vol.6
, pp. 1569-1577
-
-
Zhao, W.1
Lu, X.2
Yuan, Y.3
-
176
-
-
34548067758
-
Three new steroidal saponins from the rhizome of Paris polyphylla
-
Zhao Y, Kang LP, Liu YX, et al,. 2007. Three new steroidal saponins from the rhizome of Paris polyphylla. Magn Reson Chem 45: 739-744.
-
(2007)
Magn Reson Chem
, vol.45
, pp. 739-744
-
-
Zhao, Y.1
Kang, L.P.2
Liu, Y.X.3
-
177
-
-
0037259844
-
Effects of red orpiment on cell morphology and expression of PML mRNA and protein in NB4 and HL-60 cells
-
Zhong L, Chen F, Han J, Shao N, Ouyang R,. 2003. Effects of red orpiment on cell morphology and expression of PML mRNA and protein in NB4 and HL-60 cells. Chin Med J (Engl) 116: 148-150.
-
(2003)
Chin Med J (Engl)
, vol.116
, pp. 148-150
-
-
Zhong, L.1
Chen, F.2
Han, J.3
Shao, N.4
Ouyang, R.5
|