Selective inhibition of human leukemia cell growth and induction of cell cycle arrest and apoptosis by pseudolaric acid B

Journal of Cancer Research and Clinical Oncology

Volumn 136, Issue 9, 2010, Pages 1333-1340

  Ma, Guoyi ^a   Chong, Li ^b   Li, Xing Cong ^a   Khan, Ikhlas A ^a,c   Walker, Larry A ^a,c   Khan, Shabana I ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b University of Sydney   (Australia)

^c UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Apoptosis; Cell cycle; Cytotoxicity; Leukemia; Peripheral blood mononuclear cells; Pseudolaric acid B

Indexed keywords

CASPASE 3; CASPASE 7; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); PSEUDOLARIC ACID B; TUBULIN; DITERPENE;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL VIABILITY; CHRONIC MYELOID LEUKEMIA; COLONY FORMATION; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; MITOSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMERIZATION; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; CELL CYCLE; CELL PROLIFERATION; CELL STRAIN HL 60; CELL STRAIN K 562; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; ISOLATION AND PURIFICATION; LEUKEMIA; PATHOLOGY; PINACEAE; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; K562 CELLS; LEUKEMIA; PINACEAE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77955482084     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-010-0784-0     Document Type: Article

References (30)

1. GM Cohen 1997 Caspases: the executioners of apoptosis Biochem J 326 1 16 1:CAS:528:DyaK2sXlvFChsL4%3D 9337844
2. G Cragg M Suffness 1988 Metabolism of plant-derived anticancer agents Pharmacol Ther 37 425 461 10.1016/0163-7258(88)90006-X 10.1016/0163-7258(88) 90006-X 1:CAS:528:DyaL1cXltVeqs7o%3D 3290912
3. GM Cragg DJ Newman KM Snader 1997 Natural products in drug discovery and development J Nat Prod 60 52 60 10.1021/np9604893 10.1021/np9604893 1:CAS:528:DyaK2sXitVOiug%3D%3D 9014353
4. S Desagher JC Martinou 2000 Mitochondria as the central control point of apoptosis Trends Cell Biol 10 369 377 10.1016/S0962-8924(00)01803-1 10.1016/S0962-8924(00)01803-1 1:CAS:528:DC%2BD3cXls1CktLk%3D 10932094
5. DE Gerber 2008 Targeted therapies: a new generation of cancer treatments Am Fam Physician 77 311 319 18297955
6. XF Gong MW Wang Z Wu S Tashiro S Onodera T Ikejima 2004 Pseudolaric acid B induces apoptosis via activation of c Jun N-terminal kinase and caspase-3 in hela cells Exp Mol Med 31 551 556
7. XF Gong MW Wang S Tashiro S Onodera T Ikejima 2005 Pseudolaric acid B induces apoptosis through P53 and Bax/Bcl-2 Pathways in human melanoma A 375-S2 cells Arch Pharm Res 28 68 72 10.1007/BF02975138 10.1007/BF02975138 1:CAS:528:DC%2BD2MXht12htrg%3D 15742811
8. XF Gong MW Wang S Tashiro S Onodera T Ikejima 2005 Pseudolaric acid B induces human melanoma A 375-S2 cell apoptosis in vitro Zhongguo Zhong Yao Za Zhi 30 55 57 1:CAS:528:DC%2BD28Xlt1Kjsbg%3D 15714803
9. MA Jordan 2002 Mechanism of action of anticancer drugs that interact with microtubule and tubulin Curr Med Chem Anticancer Agents 2 1 17 10.2174/1568011023354290 1:CAS:528:DC%2BD38XislGmurg%3D 12678749
10. MA Jordan D Thrower L Wilson 1991 Mechanism of inhibition of cell proliferation by Vinca alkaloids Cancer Res 51 2212 2221 1:CAS:528: DyaK3MXhvF2jtbk%3D 2009540
11. SI Khan AC Nimrod M Mehrpooya JL Nitiss LA Walker AM Clark 2002 Antifungal activity of eupolauridine and its action on DNA topoisomerases Antimicrob Agents Chemother 46 1785 1792 10.1128/AAC.46.6.1785-1792.2002 1:CAS:528:DC%2BD38XktFCms7g%3D 12019091
12. S Larson W Stock 2008 Progress in the treatment of adults with acute lymphoblastic leukemia Curr Opin Hematol 15 400 407 10.1097/MOH.0b013e3283034697 10.1097/MOH.0b013e3283034697 18536580
13. E Li AM Clark CD Hufford 1995 Antifungal evaluation of pseudolaric acid B, a major constituent of Pseudolarix kaempferi J Nat Prod 58 57 67 10.1021/np50115a007 10.1021/np50115a007 1:CAS:528:DyaK2MXktlKqtLw%3D 7760078
14. XC Li HN Elsohly AL Nimrod AM Clark 1999 Two auronols from Pseudolarix amabilis J Nat Prod 62 767 7669 10.1021/np980469w 10.1021/np980469w 1:CAS:528:DyaK1MXit1aktbs%3D 10346966
15. KS Li XF Gu P Li Z Zhang YS Zhao ZJ Yao NQ Qu BY Wang 2005 Effect of pseudolaric acid B on gastric cancer cells: inhibition of proliferation and induction of apoptosis World J Gastroenterol 11 7555 7559 1:CAS:528: DC%2BD28Xhs1Kls78%3D 16437677
16. SW Lowe AW Lin 2000 Apoptosis in cancer Carcinogenesis 21 485 495 10.1093/carcin/21.3.485 10.1093/carcin/21.3.485 1:CAS:528:DC%2BD3cXitVeitro%3D 10688869
17. G Ma SI Khan J Mustafa LA Walker IA Khan 2005 Anticancer activity and possible mode of action of 4-O-podophyllotoxinyl 12-hydroxyl-ocadec-Z-9-enoate Lipids 40 303 308 10.1007/s11745-005-1386-0 10.1007/s11745-005-1386-0 1:CAS:528:DC%2BD2MXktFeju7w%3D 15957257
18. G Ma SI Khan NH Fisher IA Khan DS Pasco 2007 Inhibition of NF-κB-mediated transcription and induction of apoptosis by melampolides and repandolides Cancer Chemother Pharmacol 60 35 43 10.1007/s00280-006-0344-0 10.1007/s00280-006-0344-0 1:CAS:528:DC%2BD2sXksVOgs7c%3D 17149609
19. D Pan ZL Li CQ Hu K Chen JJ Chang KH Lee 1990 Antitumor agents: 109. The cytotoxic principles of Pseudolarix kaempferi: pseudolaric acid A and B and related derivatives Planta Med 56 383 385 10.1055/s-2006-960989 10.1055/s-2006-960989 1:CAS:528:DyaK3MXhslSqtA%3D%3D 2236294
20. CH Pui WE Evans 2006 Treatment of childhood acute lymphoblastic leukemia N Engl J Med 354 166 178 10.1056/NEJMra052603 10.1056/NEJMra052603 1:CAS:528:DC%2BD28XisFWksQ%3D%3D 16407512
21. CH Pui S Jha 2007 New therapeutic strategies for the treatment of acute lymphoblastic leukaemia Nat Rev Drug Discov 6 149 165 10.1038/nrd2240 10.1038/nrd2240 1:CAS:528:DC%2BD2sXhtFGlsrs%3D 17268486
22. S Sen M D'Incalci 1992 Apoptosis: biochemical events and relevance to cancer chemotherapy FEBS Lett 307 122 127 10.1016/0014-5793(92)80914-3 10.1016/0014-5793(92)80914-3 1:CAS:528:DyaK38Xlt1eqsrg%3D 1639187
23. CJ Sherr 1996 Cancer cell cycles Science 274 1672 1677 10.1126/science.274.5293.1672 10.1126/science.274.5293.1672 1:CAS:528: DyaK28XntlyktLs%3D 8939849
24. Q Shi KC Chen SL Morrist-Natschke KH Lee 1998 Recent progress in the development of tubulin inhibitors as antimitotic antitumor agents Curr Pharm Des 4 219 248 1:CAS:528:DyaK1cXjvFCqur0%3D 10197041
25. 2/M cell arrest in HT 29 cells Toxicology 175 123 142 10.1016/S0300-483X(02)00073-2 10.1016/S0300- 483X(02)00073-2 1:CAS:528:DC%2BD38XktFKhtr0%3D 12049842
26. HK Wang SL Morris-Natschke KH Lee 1997 Recent advances in the discovery and development of topoisomerase inhibitors as antitumor agents Med Res Rev 4 367 425 10.1002/(SICI)1098-1128(199707)17:4<367::AID-MED3>3.0.CO;2-U 10.1002/(SICI)1098-1128(199707)17:4<367::AID-MED3>3.0.CO;2-U
27. VKW Wong P Chiu SSM Chung LMC Chow YZ Zhao BB Yang BCB Ko 2005 Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo Clin Cancer Res 11 6002 6011 10.1158/1078-0432.CCR-05-0209 10.1158/1078-0432.CCR-05- 0209 1:CAS:528:DC%2BD2MXos1CisLo%3D 16115945
28. SP Yang L Dong Y Wang Y Wu JM Yue 2003 Antifungal diterpenoids of Pseudolarix kaempferi, and their structure-activity relationship study Bioorg Med Chem 11 4577 4584 10.1016/S0968-0896(03)00531-5 10.1016/S0968-0896(03)00531- 5 1:CAS:528:DC%2BD3sXns1Klsbc%3D 14527554
29. YL Zhang RZ Lu AL Yan 1990 Inhibition of ova fertilizability by pseudolaric acid B in hamster Acta Pharmacol Sin 11 60 62 1:CAS:528: DyaK3cXhvFajurY%3D
30. BN Zhou BP Ying GQ Song ZX Chen J Han YF Yan 1983 Pseudolaric acids from Pseudolarix kaempferi Planta Med 47 35 38 10.1055/s-2007-969944 10.1055/s-2007-969944 1:CAS:528:DyaL3sXitFars7s%3D 17405089