Protein tyrosine kinase, JNK, and ERK involvement in pseudolaric acid B-induced apoptosis of human breast cancer MCF-7 cells

Acta Pharmacologica Sinica

Volumn 29, Issue 9, 2008, Pages 1069-1076

  Yu, Jing Hua ^a   Wang, Hong Jun ^a   Li, Xiang Ru ^a   Tashiro, Shin Ichi ^b   Onodera, Satoshi ^b   Ikejima, Takashi ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; C Jun N terminal kinase; Extracellular signal regulated kinase; Human breast cancer MCF 7; Protein tyrosine kinase; Pseudolaric acid

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3 BROMO 5 TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; GENISTEIN; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN TYROSINE KINASE; PSEUDOLARIC ACID B; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL DEATH; CELL STRAIN MCF 7; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DITERPENES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENISTEIN; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; L-LACTATE DEHYDROGENASE; NEOPLASM PROTEINS; PROTEIN-TYROSINE KINASES;

EID: 51349130575     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2008.00835.x     Document Type: Article

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