Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes

Cancer Letters

Volumn 256, Issue 2, 2007, Pages 259-266

  Yang, Yong ^a   Yang, Lan ^a   You, Qi Dong ^a   Nie, Fei Fei ^a   Gu, Hong Yan ^a   Zhao, Li ^a   Wang, Xiao Tang ^b   Guo, Qing Long ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b FLORIDA INTERNATIONAL UNIVERSITY   (United States)

Author keywords

Apoptosis; Bax; Bcl 2; Caspase 3; Gambogic acid

Indexed keywords

CASPASE 3; GAMBOGIC ACID; NATURAL PRODUCT; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG RETENTION; DRUG SAFETY; DRUG SELECTIVITY; EMBRYO; FEMALE; HEPATOMA CELL; HUMAN; HUMAN CELL; KIDNEY; LIVER CELL; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SHAPE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEPATOCYTES; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; XANTHONES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

GARCINIA; MUS;

EID: 34548679604     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2007.06.014     Document Type: Article

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