Novel diterpenoids with potent inhibitory activity against endothelium cell HMEC and cytotoxic activities from a well-known TCM plant Daphne genkwa

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 3, 2005, Pages 645-655

  Zhan, Zha Jun ^a   Fan, Cheng Qi ^a   Ding, Jian ^a   Yue, Jian Min ^a  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

Cytotoxic activities; Daphne genkwa; Inhibitory activity against endothelium cell HMEC; Novel daphnane type diterpenoids

Indexed keywords

ANTINEOPLASTIC AGENT; DAPHNE GENKWA EXTRACT; DITERPENOID; GENKWANINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CHINESE MEDICINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DAPHNE GENKWA; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IC 50; MEDICINAL PLANT; MOUSE; NONHUMAN; STRUCTURE ANALYSIS; TUMOR CELL LINE;

CELL LINE; DAPHNE; DITERPENES; ENDOTHELIUM; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

DAPHNE;

EID: 11844289554     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.10.054     Document Type: Article

References (31)

1. F.J. Evans, and C.J. Soper J. Nat. Prod. 41 1978 193
2. S.M. Kupchan, and R.L. Baxter Science 187 1974 652
3. S.M. Kupchan, Y. Shizuri, J.G. Sweeny, H.R. Haynes, M.S. Shen, J.C. Barrick, R.F. Bryan, and D.V.D. Helm J. Am. Chem. Soc. 98 1976 5719
4. M.M. Badawi, S.S. Handa, A.D. Kinghorn, G.A. Cordell, and N.R. Farnsworth J. Pharm. Sci. 72 1983 1285
5. R.G. Powell, D. Weisleder, and C.R. Smith J. Nat. Prod. 48 1985 102
6. M.I. Tyler, and M.E.H. Howden J. Nat. Prod. 48 1985 440
7. W. Adolf, and E. Hecker Planta Med. 45 1982 177
8. W. Adolf, S.F. Dossaji, E.H. Seip, and E. Hecker Phytochemistry 24 1985 2047
9. W. Adolf, E.H. Seip, and E. Hecker J. Nat. Prod. 51 1988 662
10. W.D. He, M. Cik, A. Lesage, I.V.D. Linden, N.D. Kimpe, G. Appendino, J. Bracke, S.G. Mathenge, F.P. Mudida, J.E. Leysen, and L.V. Puyvelde J. Nat. Prod. 63 2000 1185
11. J.R. Carney, J.M. Krenisky, R.T. Williamson, J. Luo, T.J. Carlson, V.L. Hsu, and J.L. Moswa J. Nat. Prod. 62 1999 345
12. B.P. Ying, C.R. Wang, B.N. Zhou, B.C. Pan, and J.S. Liu Huaxue Xuebao 35 1977 103
13. C.R. Wang, Z.X. Cheng, B.P. Ying, B.N. Zhou, J.S. Liu, and B.C. Pan Huaxue Xuebao 39 1981 421
14. C.R. Wang, H.Z. Huang, R.S. Xu, Y.Y. Dou, X.C. Wu, Y. Li, and S.H. Ouyang Huaxue Xuebao 40 1982 835
15. B.H. Hu, H. Sha, C.R. Wang, D.F. Yu, X.C. Wu, and X.G. Yu Huaxue Xuebao 43 1985 460
16. Z.P. Gu, C.R. Wang, Z.Y. Liang, L.J. Lin, R.F. Lu, S.X. Zhao, and B.N. Zhou Reprod. Contracept. 9 1989 48
17. K. Sakata, K. Kawazu, T. Mitsui, and N. Masaki Agri. Biol. Chem. 35 1971 2113
18. G. Appendino, and A. Krenisky Life Sci. 60 1997 681
19. Jiangsu New Medical College The Encyclopedia of Traditional Chinese Medicine 2nd ed. 1985 Shanghai Science and Technology Shanghai pp 2573
20. R. Kasai, K.H. Lee, and H.C. Huang Phytochemistry 20 1981 2592
21. B.H. Hu, H. Sha, Z.W. He, and X.C. Wu Huaxue Xuebao 44 1986 843
22. K. Baba, M. Taniguchi, and M. Kozawa Phytochemistry 31 1992 975
23. K. Baba, M. Taniguchi, H. Ohishi, and M. Kozawa Phytochemistry 32 1993 221
24. K. Baba, M. Taniguchi, H. Ohishi, and M. Kozawa Phytochemistry 33 1993 913
25. P. Carmeliet, and K.R. Jain Nature 407 2000 249
26. B.S. Croix, C. Rago, V. Velculescu, G. Traverso, E.M. Romans, A. Lal, G.J. Riggins, C. Lengauer, B. Vogelstein, and K.W. Kinzler Science 289 2000 1197
27. C. Unger Drugs Future 22 12 1997 1337
28. W. Adolf, and E. Hecker J. Nat. Prod. 47 1984 482
29. K. Hayashi, Y. Nakanishi, K.F. Bastow, G. Cragg, H. Nozaki, and K.H. Lee J. Nat. Prod. 66 2003 125
30. B. Pauwels, A.E.C. Korst, C.M.J. De Pooter, G.G.O. Pattyn, H.A.J. Lambrechts, M.F.D. Baay, F. Lardon, and J.B. Vermorken Cancer Chemother. Pharmacol. 51 2003 221
31. D.J. Pan, Z.L. Li, C.Q. Hu, K. Chen, J.J. Chang, and K.H. Lee Planta Med. 56 1990 383