Evodiamine stabilizes topoisomerase I-DNA cleavable complex to inhibit topoisomerase I activity

Molecules

Volumn 14, Issue 4, 2009, Pages 1342-1352

  Chan, Agnes L F ^a   Chang, Wen Shin ^b   Chen, Li Min ^c   Lee, Chi Ming ^c   Chen, Chiao En ^d   Lin, Chun Mao ^c,e   Hwang, Jau Lang ^d  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Covalent complex; Evodiamine; Topoisomerase

Indexed keywords

DNA TOPOISOMERASE; EVODIAMINE; PLANT EXTRACT; QUINAZOLINE DERIVATIVE;

ANIMAL; ARTICLE; BREAST TUMOR; CHEMICAL STRUCTURE; CHEMISTRY; DNA SUPERCOILING; DRUG ANTAGONISM; ENZYME STABILITY; FEMALE; HUMAN; MACROMOLECULE; METABOLISM; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA TOPOISOMERASES, TYPE I; DNA, SUPERHELICAL; ENZYME STABILITY; FEMALE; HUMANS; MACROMOLECULAR SUBSTANCES; MOLECULAR STRUCTURE; PLANT EXTRACTS; QUINAZOLINES;

EID: 66349130754     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules14041342     Document Type: Article

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