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Volumn 67, Issue 2, 2004, Pages 129-135

Camptothecin and Taxol: Historic Achievements in Natural Products Research

Author keywords

[No Author keywords available]

Indexed keywords

'TAXUS'; AMSACRINE; ANTHRACYCLINE; ANTIINFECTIVE AGENT; BETA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; CAMPTOTHECIN DERIVATIVE; DNA TOPOISOMERASE; DOCETAXEL; DOXORUBICIN; ETOPOSIDE; EXATECAN; HISTAMINE H2 RECEPTOR ANTAGONIST; IRINOTECAN; LURTOTECAN; MITOXANTRONE; NALIDIXIC ACID; PACLITAXEL; RUBITECAN; TAXANE DERIVATIVE; TOPOTECAN; UNCLASSIFIED DRUG;

EID: 1442334562     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np030498t     Document Type: Review
Times cited : (325)

References (50)
  • 13
    • 1442340405 scopus 로고    scopus 로고
    • May (for Camptosar, ca. $574 million)
    • The sales figures for the camptothecin analogues come from the 2002 Annual Report for GlaxoSmithKline (for Hycamtin, ca. $140 million) and the 2002 sales figures for the top 400 prescription drugs reported by Med. Ad. News in May 2003 (for Camptosar, ca. $574 million).
    • (2003) Med. Ad. News
  • 17
    • 0142144344 scopus 로고    scopus 로고
    • Cambridge University Press: Cambridge, UK
    • Goodman, J.; Walsh, V. The Story of Taxol; Cambridge University Press: Cambridge, UK, 2001; p 282.
    • (2001) The Story of Taxol , pp. 282
    • Goodman, J.1    Walsh, V.2
  • 20
    • 77956791953 scopus 로고
    • Bristol, J. A., Ed.; Academic Press: San Diego
    • Suffness, M. In Annual Reports in Medicinal Chemistry; Bristol, J. A., Ed.; Academic Press: San Diego, 1993; Vol. 28, pp 305-314.
    • (1993) Annual Reports in Medicinal Chemistry , vol.28 , pp. 305-314
    • Suffness, M.1
  • 23
    • 1442340405 scopus 로고    scopus 로고
    • May
    • According to Reuters Business Insight on Healthcare, their report of the "Cancer Market Outlook to 2008" estimates the global cytotoxics market in 2002 at $8.9 billion. Sales in 2002 for Taxotere, as reported by Med. Ad. News in May 2003 in "The Top 400 Prescription Drugs" totaled ca. $1.192 billion. The same report showed 2002 sales of Taxol to be ca. $857 million. As explained in ref 13, the combined sales of the camptothecin analogues represent nearly $750 million. Thus, the total sales of taxol, docetaxel (Taxotere), and camptothecin analogues represent more than $2.75 billion, or about one-third of the global antineoplastic agent market.
    • (2003) Med. Ad. News
  • 34
    • 1442315840 scopus 로고    scopus 로고
    • Personal communication from T. C. Rowe to D. J. Kroll (Oct. 1989)
    • Personal communication from T. C. Rowe to D. J. Kroll (Oct. 1989).
  • 50
    • 1442266881 scopus 로고    scopus 로고
    • The cover of the January-June 2004 issues of the Journal of Natural Products shows a photograph of the plaque awarded by the American Chemical Society to Research Triangle Institute in connection with this National Historic Chemical Landmark.
    • (2004) Journal of Natural Products


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.