Dauricine inhibits insulin-like growth factor-I-induced hypoxia inducible factor 1α protein accumulation and vascular endothelial growth factor expression in human breast cancer cells

Acta Pharmacologica Sinica

Volumn 30, Issue 5, 2009, Pages 605-616

  Tang, Xu Dong ^a,b   Zhou, Xin ^a   Zhou, Ke Yuan ^b  

^a WUHAN UNIVERSITY   (China)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

Angiogenesis; Dauricine; Hypoxia inducible factor 1 ; Insulin like growth factor I; Vascular endothelial growth factor

Indexed keywords

DAURICINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UMBILICAL VEIN; WESTERN BLOTTING;

ANGIOGENESIS INHIBITORS; BENZYLISOQUINOLINES; BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; ENDOTHELIAL CELLS; FEMALE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; INSULIN-LIKE GROWTH FACTOR I; PREGNANCY; PROTEIN SYNTHESIS INHIBITORS; SIGNAL TRANSDUCTION; TETRAHYDROISOQUINOLINES; TRANSCRIPTIONAL ACTIVATION; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 66749137756     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.8     Document Type: Article

References (29)

1. Yang XY, Jiang SQ, Zhang L, Liu QN, Gong PL. Inhibitory efect of dauricine on inflammatory process following focal cerebral ischemia/reperfusion in rats. Am J Chin Med 2007; 35: 477-86.
2. Su YM, Zhang C, Xiao JY, Gang HL, Wang ZG, Hua D. Effects of PAMD on the proliferation of human tumor cells of PC-3 and BT5637. Harbin Yi Ke Da Xue Xue Ba 2007; 41: 129-31. Chinese.
3. Al-Harris ES, Al-Janabi AA, Al-Toriahi KM, Yasseen AA. Over expression of vascular endothelial growth factor in correlation to Ki-67, grade, and stage of breast cancer. Saudi Med J 2008; 29: 1099-104.
4. Applanat MP, Buteau-Lozano H, Herve MA, Corpet A. Vascular endothelial growth factor is a target gene for estrogen receptor and contributes to breast cancer progression. Adv Exp Med Biol 2008; 617: 437-44.
5. Slomiany MG, Rosenzweig SA. Hypoxia-inducible factor-dependent and -independent regulation of insulin-like growth factor-1-stimulated vascular endothelial growth factor secretion. J Pharmacol Exp Ter 2006; 318: 666-75.
6. Catrina SB, Botusan IR, Rantanen A, Catrina AI, Pyakurel P, Savu O, et al. Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I. Clin Cancer Res 2006; 12: 4506-14.
7. Beppu K, Nakamura K, Linehan WM, Rapisarda A, Thiele CJ. Topotecan blocks hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression induced by insulin-like growth factor-I in neuroblastoma cells. Cancer Res 2005; 65: 4775-81.
8. Cao Z, Fang J, Xia C, Shi X, Jiang BH. trans-3,4,5′- Trihydroxy-stibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells. Clin Cancer Res 2004; 10: 5253-63.
9. Kondo S, Seo SY, Yoshizaki T, Wakisaka N, Furukawa M, Joab I, et al. EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells. Cancer Res 2006; 66: 9870-7.
10. Tang X, Zhang Q, Nishitani J, Brown J, Shi SH, Le AD. Over-expres sion of human papillomavirus type 16 oncoproteins enhances hypoxia-inducible factor 1alpha protein accumulation and vascular endothelial growth factor expression in human cervical carcinoma cells. Clin Cancer Res 2007; 13: 2568-76.
11. Zhang Q, Tang X, Zhang ZF, Velikina R, Shi S, Le AD. Nicotine induces hypoxia-inducible factor-1alpha expression in human lung cancer cells via nicotinic acetylcholine receptor-mediated signaling pathways. Clin Cancer Res 2007; 13: 4686- 94.
12. Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004; 10: 789-99.
13. Gordan JD, Simon MC. Hypoxia-inducible factors: central regulators of the tumor phenotype. Curr Opin Genet Dev 2007; 17: 71-7.
14. Lopez-Lazaro M. Hypoxia-inducible factor 1 as a possible target for cancer chemoprevention. Cancer Epidemiol Biomarkers Prev 2006; 15: 2332-5.
15. Kimbro KS, Simons JW. Hypoxia-inducible factor-1 in human breast and prostate cancer. Endocr Relat Cancer 2006; 13: 739-49.
16. Lin S, Tsai SC, Lee CC, Wang BW, Liou JY, Shyu KG. Berberine inhibits HIF-1alpha expression via enhanced proteolysis. Mol Pharmacol 2004; 66: 612-9.
17. Cai XF, Jin X, Lee D, Yang Y T, Lee K, Hong YS, et al. Phenanthro-quinolizidine alkaloids from the roots of boehmeria pannosa potently inhibit hypoxia-inducible factor-1 in AGS human gastric cancer cells. J Nat Prod 2006; 69: 1095-7.
18. Liu L, Ning X, Sun L, Shi Y, Han S, Guo C, et al. Involvement of MGr1-Ag/37LRP in the vincristine-induced HIF-1 expression in gastric cancer cells. Mol Cell Biochem 2007; 303: 151-60.
19. Chang TC, Huang CJ, Tam K, Chen SF, Tan KT, Tsai MS, et al. Stabilization of hypoxia-inducible factor-1alpha by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells. J Biol Chem 2005; 280: 36567-74.
20. Jung YJ, Isaacs JS, Lee S, Trepel J, Neckers L. IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifes HIF-1 as a critical link between infammation and oncogenesis. FASEB J 2003; 17: 2115-7.
21. Zhang X, Kon T, Wang H, Li F, Huang Q, Rabbani ZN, et al. Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1α. Cancer Res 2004; 64: 8139-42.
22. Slomiany MG, Black LA, Kibbey MM, Day TA, Rosenzweig SA. IGF-1 induced vascular endothelial growth factor secretion in head and neck squamous cell carcinoma. Biochem Biophys Res Commun 2006; 342: 851-8.
23. Fukuda R, Hirota K, Fan F, Jung YD, Ellis LM, Semenza GL. Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells. J Biol Chem 2002; 277: 38205-11.
24. Treins C, Giorgetti-Peraldi S, Murdaca J, Semenza GL, Van Obberghen E. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway. J Biol Chem 2002; 277: 27975-81.
25. Munaron L, Tomatis C, Pla A. The Secret Marriage between calcium and tumor angiogenesis. Technol Cancer Res Treat 2008; 7: 335-40.
26. Khosravi Shahi P, Soria Lovelle A, Pérez Manga G. Tumoral angiogenesis and breast cancer. Clin Transl Oncol 2009; 11: 138-42.
27. Gingras A, Raught B, Sonenberg N. Regulation of translation initiation by FRP/mTOR. Genes Dev 2001; 15: 807-26.
28. Mita MM, Mita A, Rowinsky EK. Mammalian target of rapamycin: a new molecular target for breast cancer. Clin Breast Cancer 2003; 4: 126-37.
29. Zhang Q, Tang X, Lu Q, Zhang Z, Rao J, Le AD. Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells. Mol Cancer Ter 2006; 5: 1227-38. 30 Zhang Q, Tang X, Lu QY, Zhang ZF, Brown J, Le AD. Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells. Mol Cancer Ther 2005; 4: 1465-74.