Periplocin from Cortex periplocae inhibits cell growth and down-regulates survivin and c-myc expression in colon cancer in vitro and in vivo via β-catenin/TCF signaling

Oncology Reports

Volumn 24, Issue 2, 2010, Pages 375-383

  Zhao, Lianmei ^a   Shan, Baoen ^a   Du, Yanyan ^a   Wang, Mingxia ^a   Liu, Lihua ^a   Ren, Feng Zhi ^b  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b North China Pharmaceutical Corporation   (China)

Author keywords

Anti tumor; Colon cancer cells; Periplocin; Xenografts in nude mice; catenin TCF signaling

Indexed keywords

BETA CATENIN; DNA; MYC PROTEIN; PERIPLOCIN; PLANT EXTRACT; SURVIVIN; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BIRC5 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; SAPONIN;

APOPTOSIS; ARTICLE; BINDING AFFINITY; BINDING SITE; CANCER INHIBITION; CELL LYSATE; COLON CANCER; CONTROLLED STUDY; CORTEX PERIPLOCAE; CYTOSOL; DNA BINDING; DOSE RESPONSE; DOWN REGULATION; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PERIPLOCA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; BIOLOGICAL MODEL; CARCINOMA; CELL PROLIFERATION; CHEMISTRY; COLON TUMOR; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; ONCOGENE MYC; PATHOLOGY; PHYSIOLOGY; TUMOR CELL CULTURE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BETA CATENIN; CARCINOMA; CELL PROLIFERATION; COLONIC NEOPLASMS; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MYC; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; PERIPLOCA; SAPONINS; SIGNAL TRANSDUCTION; TCF TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 77954381626     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or-00000870     Document Type: Article

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