γH2AX as a novel endpoint to detect DNA damage: Applications for the assessment of the in vitro genotoxicity of cigarette smoke

Toxicology in Vitro

Volumn 26, Issue 7, 2012, Pages 1075-1086

  Garcia Canton, Carolina ^a,b   Anadón, Arturo ^b   Meredith, Clive ^a  

^a BRITISH AMERICAN TOBACCO   (United Kingdom)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

H2AX; Cigarette smoke; DNA; DNA damage; Genotoxicity; In vitro

Indexed keywords

BIOLOGICAL MARKER; CIGARETTE SMOKE; NUCLEAR PROTEIN; PROTEIN GAMMA H2AX; UNCLASSIFIED DRUG;

AMES TEST; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; DNA DAMAGE; DNA DETERMINATION; DNA MARKER; DOUBLE STRANDED DNA BREAK; GENETIC SCREENING; GENOTOXICITY; HUMAN; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; LYMPHOMA CELL LINE; MICRONUCLEUS TEST; MUTAGENICITY; MUTATIONAL ANALYSIS; NONHUMAN; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; REVIEW; TOXICITY TESTING;

ANIMALS; CELL LINE, TUMOR; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; HISTONES; MUTAGENICITY TESTS; MUTAGENS; PHOSPHORYLATION; SMOKE; TOBACCO PRODUCTS;

NICOTIANA TABACUM;

EID: 84866042698     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.06.006     Document Type: Review

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