Use of the γH2AX assay for assessing the genotoxicity of polycyclic aromatic hydrocarbons in human cell lines

Toxicology Letters

Volumn 199, Issue 2, 2010, Pages 182-192

  Audebert, M ^a   Riu, A ^a   Jacques, C ^a   Hillenweck, A ^a   Jamin, E L ^a   Zalko, D ^a   Cravedi, J P ^a  

^a CNRS   (France)

Author keywords

Genotoxicity; H2AX; HepG2; Metabolism; Polycyclic aromatic hydrocarbons

Indexed keywords

3 METHYLCHOLANTHRENE; BENZO[A]PYRENE; FLUORANTHENE; GAMMA HISTONE H2AX; HISTONE H2AX; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG; FLUORENE DERIVATIVE; H2AFX PROTEIN, HUMAN; HISTONE;

ARTICLE; ASSAY; BIOTRANSFORMATION; CELL METABOLISM; CELL STRAIN CACO 2; CELL STRAIN HEPG2; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; GENOTOXICITY; HUMAN; HUMAN CELL; METABOLIC RATE; PRIORITY JOURNAL; TOXICITY TESTING; DNA DAMAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; METABOLISM; MUTAGEN TESTING; PHOSPHORYLATION; TOXICITY; TUMOR CELL LINE;

BENZO(A)PYRENE; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA DAMAGE; FLUORENES; HISTONES; HUMANS; IMMUNOHISTOCHEMISTRY; METHYLCHOLANTHRENE; MUTAGENICITY TESTS; PHOSPHORYLATION; POLYCYCLIC HYDROCARBONS, AROMATIC;

ANIMALIA;

EID: 77957946614     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.08.022     Document Type: Article

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