Benzo[a]pyrene induces complex H2AX phosphorylation patterns by multiple kinases including ATM, ATR, and DNA-PK

Toxicology in Vitro

Volumn 25, Issue 1, 2011, Pages 91-99

  Yan, Chunlan ^a   Lu, Jing ^a   Zhang, Guanglin ^a   Gan, Tieer ^a   Zeng, Qunli ^a   Shao, Zhengping ^a   Duerksen Hughes, Penelope J ^b   Yang, Jun ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Benzo a pyrene; Caffeine; DNA damage; H2AX; Phosphatidylinositol 3 kinase

Indexed keywords

ATM PROTEIN; ATR PROTEIN; BENZO[A]PYRENE; CAFFEINE; DNA DEPENDENT PROTEIN KINASE; HISTONE H2AX; WORTMANNIN;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA MODIFICATION; FIBROBLAST; GENE ACTIVITY; GENE INACTIVATION; GENOTOXICITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OSTEOSARCOMA CELL; PROTEIN PHOSPHORYLATION; REACTION TIME;

ANDROSTADIENES; ANIMALS; BENZO(A)PYRENE; CAFFEINE; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; HISTONES; HUMANS; MICE; MUTAGENS; OSMOLAR CONCENTRATION; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 78650524370     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.09.012     Document Type: Article

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