Assembly and function of DNA double-strand break repair foci in mammalian cells

DNA Repair

Volumn 9, Issue 12, 2010, Pages 1219-1228

  Bekker Jensen, Simon ^a   Mailand, Niels ^a  

^a University of Copenhagen   (Denmark)

Author keywords

DNA damage response; DNA double strand breaks; DNA repair; Ionizing Radiation Induced Foci; Phosphorylation; Ubiquitin

Indexed keywords

53BP1 PROTEIN; BRCA1 PROTEIN; DOUBLE STRANDED DNA; GAMMA H2AX; HERC2 PROTEIN; HISTONE H2A; HISTONE H2AX; MDC1 PROTEIN; NUCLEIC ACID BINDING PROTEIN; REGULATOR PROTEIN; RNF168 PROTEIN; RNF8 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

BINDING SITE; CELL COMPARTMENTALIZATION; CELL NUCLEUS; DNA REPAIR; DOUBLE STRANDED DNA BREAK; HUMAN; IONIZING RADIATION INDUCED FOCI; MAMMAL CELL; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN TRANSPORT; REVIEW; SIGNAL TRANSDUCTION; SUMOYLATION; UBIQUITINATION; VIRUS CELL INTERACTION;

ANIMALS; BRCA1 PROTEIN; CELL NUCLEUS; CHROMATIN; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-BINDING PROTEINS; GENOMIC INSTABILITY; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HISTONES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MULTIPROTEIN COMPLEXES; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; TRANS-ACTIVATORS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

MAMMALIA;

EID: 78649450619     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2010.09.010     Document Type: Review

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