메뉴 건너뛰기




Volumn 604, Issue 1-2, 2006, Pages 8-18

DNA damage evaluated by γH2AX foci formation by a selective group of chemical/physical stressors

Author keywords

H2AX; Cytotoxicity; Double strand breaks; Genotoxin

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN A; DIMETHYL SULFOXIDE; DNA; ETHYLNITROSOUREA; HISTONE H2AX; MESYLIC ACID METHYL ESTER; N (2 FLUORENYL)ACETAMIDE; SODIUM CHLORIDE;

EID: 33645979960     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2005.12.004     Document Type: Article
Times cited : (109)

References (47)
  • 5
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., and Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273 (1998) 5858-5868
    • (1998) J. Biol. Chem. , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 6
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • Paull T.T., Rogakou E.P., Yamazaki V., Kirchgessner C.U., Gellert M., and Bonner W.M. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10 (2000) 886-895
    • (2000) Curr. Biol. , vol.10 , pp. 886-895
    • Paull, T.T.1    Rogakou, E.P.2    Yamazaki, V.3    Kirchgessner, C.U.4    Gellert, M.5    Bonner, W.M.6
  • 7
    • 0042242630 scopus 로고    scopus 로고
    • Expression of phosphorylated histone H2AX in cultured cell lines following exposure to X-rays
    • MacPhail S.H., Banath J.P., Yu T.Y., Chu E.H., Lambur H., and Olive P.L. Expression of phosphorylated histone H2AX in cultured cell lines following exposure to X-rays. Int. J. Radiat. Biol. 79 (2003) 351-358
    • (2003) Int. J. Radiat. Biol. , vol.79 , pp. 351-358
    • MacPhail, S.H.1    Banath, J.P.2    Yu, T.Y.3    Chu, E.H.4    Lambur, H.5    Olive, P.L.6
  • 8
    • 1942538492 scopus 로고    scopus 로고
    • ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
    • Stiff T., O'Driscoll M., Rief N., Iwabuchi K., Lobrich M., and Jeggo P.A. ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res. 64 (2004) 2390-2396
    • (2004) Cancer Res. , vol.64 , pp. 2390-2396
    • Stiff, T.1    O'Driscoll, M.2    Rief, N.3    Iwabuchi, K.4    Lobrich, M.5    Jeggo, P.A.6
  • 9
    • 11144305946 scopus 로고    scopus 로고
    • Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors
    • Wang H., Wang M., Bocker W., and Iliakis G. Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors. J. Cell Physiol. 202 (2005) 492-502
    • (2005) J. Cell Physiol. , vol.202 , pp. 492-502
    • Wang, H.1    Wang, M.2    Bocker, W.3    Iliakis, G.4
  • 10
    • 0038143321 scopus 로고    scopus 로고
    • Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX
    • Ward I.M., Minn K., Jorda K.G., and Chen J. Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX. J. Biol. Chem. 278 (2003) 19579-19582
    • (2003) J. Biol. Chem. , vol.278 , pp. 19579-19582
    • Ward, I.M.1    Minn, K.2    Jorda, K.G.3    Chen, J.4
  • 13
    • 0141740426 scopus 로고    scopus 로고
    • Focusing on foci: H2AX and the recruitment of DNA-damage response factors
    • Fernandez-Capetillo O., Celeste A., and Nussenzweig A. Focusing on foci: H2AX and the recruitment of DNA-damage response factors. Cell Cycle 2 (2003) 426-427
    • (2003) Cell Cycle , vol.2 , pp. 426-427
    • Fernandez-Capetillo, O.1    Celeste, A.2    Nussenzweig, A.3
  • 14
    • 0037884963 scopus 로고    scopus 로고
    • Evidence for a lack of DNA double-strand break repair in human cells exposed to very low X-ray doses
    • Rothkamm K., and Lobrich M. Evidence for a lack of DNA double-strand break repair in human cells exposed to very low X-ray doses. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 5057-5062
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 5057-5062
    • Rothkamm, K.1    Lobrich, M.2
  • 15
    • 1242297828 scopus 로고    scopus 로고
    • RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult
    • Bosco E.E., Mayhew C.N., Hennigan R.F., Sage J., Jacks T., and Knudsen E.S. RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult. Nucleic Acids Res. 32 (2004) 25-34
    • (2004) Nucleic Acids Res. , vol.32 , pp. 25-34
    • Bosco, E.E.1    Mayhew, C.N.2    Hennigan, R.F.3    Sage, J.4    Jacks, T.5    Knudsen, E.S.6
  • 16
    • 8844259700 scopus 로고    scopus 로고
    • Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of gamma-H2AX
    • Ha L., Ceryak S., and Patierno S.R. Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of gamma-H2AX. Carcinogenesis 25 (2004) 2265-2274
    • (2004) Carcinogenesis , vol.25 , pp. 2265-2274
    • Ha, L.1    Ceryak, S.2    Patierno, S.R.3
  • 17
    • 1942534150 scopus 로고    scopus 로고
    • Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin
    • Huang X., Okafuji M., Traganos F., Luther E., Holden E., and Darzynkiewicz Z. Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin. Cytometry 58A (2004) 99-110
    • (2004) Cytometry , vol.58 A , pp. 99-110
    • Huang, X.1    Okafuji, M.2    Traganos, F.3    Luther, E.4    Holden, E.5    Darzynkiewicz, Z.6
  • 18
    • 0345835371 scopus 로고    scopus 로고
    • Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks
    • Banath J.P., and Olive P.L. Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks. Cancer Res. 63 (2003) 4347-4350
    • (2003) Cancer Res. , vol.63 , pp. 4347-4350
    • Banath, J.P.1    Olive, P.L.2
  • 20
    • 13944269124 scopus 로고    scopus 로고
    • Induction of H2AX phosphorylation in pulmonary cells by tobacco smoke: a new assay for carcinogens
    • Albino A.P., Huang X., Jorgensen E., Yang J., Gietl D., Traganos F., and Darzynkiewicz Z. Induction of H2AX phosphorylation in pulmonary cells by tobacco smoke: a new assay for carcinogens. Cell Cycle 3 (2004) 1062-1068
    • (2004) Cell Cycle , vol.3 , pp. 1062-1068
    • Albino, A.P.1    Huang, X.2    Jorgensen, E.3    Yang, J.4    Gietl, D.5    Traganos, F.6    Darzynkiewicz, Z.7
  • 21
    • 27144486122 scopus 로고    scopus 로고
    • Novel genotoxicity assays identify norethindrone to activate p53 and phosphorylate H2AX
    • Gallmeier E., Winter J.M., Cunningham S.C., Kahn S.R., and Kern S.E. Novel genotoxicity assays identify norethindrone to activate p53 and phosphorylate H2AX. Carcinogenesis 26 (2005) 1811-1820
    • (2005) Carcinogenesis , vol.26 , pp. 1811-1820
    • Gallmeier, E.1    Winter, J.M.2    Cunningham, S.C.3    Kahn, S.R.4    Kern, S.E.5
  • 22
    • 0031926177 scopus 로고    scopus 로고
    • A new approach to identifying genotoxic carcinogens: p53 induction as an indicator of genotoxic damage
    • Yang J., and Duerksen-Hughes P. A new approach to identifying genotoxic carcinogens: p53 induction as an indicator of genotoxic damage. Carcinogenesis 19 (1998) 1117-1125
    • (1998) Carcinogenesis , vol.19 , pp. 1117-1125
    • Yang, J.1    Duerksen-Hughes, P.2
  • 23
    • 0036081410 scopus 로고    scopus 로고
    • Regulation of proinflammatory cytokines in human lung epithelial cells infected with Mycoplasma pneumoniae
    • Yang J., Hooper W.C., Phillips D.J., and Talkington D.F. Regulation of proinflammatory cytokines in human lung epithelial cells infected with Mycoplasma pneumoniae. Infect. Immun. 70 (2002) 3649-3655
    • (2002) Infect. Immun. , vol.70 , pp. 3649-3655
    • Yang, J.1    Hooper, W.C.2    Phillips, D.J.3    Talkington, D.F.4
  • 24
    • 0035930537 scopus 로고    scopus 로고
    • Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
    • Ward I.M., and Chen J. Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J. Biol. Chem. 276 (2001) 47759-47762
    • (2001) J. Biol. Chem. , vol.276 , pp. 47759-47762
    • Ward, I.M.1    Chen, J.2
  • 25
    • 0035834693 scopus 로고    scopus 로고
    • ATM phosphorylates histone H2AX in response to DNA double-strand breaks
    • Burma S., Chen B.P., Murphy M., Kurimasa A., and Chen D.J. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem. 276 (2001) 42462-42467
    • (2001) J. Biol. Chem. , vol.276 , pp. 42462-42467
    • Burma, S.1    Chen, B.P.2    Murphy, M.3    Kurimasa, A.4    Chen, D.J.5
  • 27
    • 0026377650 scopus 로고
    • Interaction between ionizing radiation and supercoiled DNA within human tumor cells
    • Vaughan A.T., Milner A.M., Gordon D.G., and Schwartz J.L. Interaction between ionizing radiation and supercoiled DNA within human tumor cells. Cancer Res. 51 (1991) 3857-3861
    • (1991) Cancer Res. , vol.51 , pp. 3857-3861
    • Vaughan, A.T.1    Milner, A.M.2    Gordon, D.G.3    Schwartz, J.L.4
  • 28
    • 13744252931 scopus 로고    scopus 로고
    • Heat shock induces phosphorylation of histone H2AX in mammalian cells
    • Kaneko H., Igarashi K., Kataoka K., and Miura M. Heat shock induces phosphorylation of histone H2AX in mammalian cells. Biochem. Biophys. Res. Commun. 328 (2005) 1101-1106
    • (2005) Biochem. Biophys. Res. Commun. , vol.328 , pp. 1101-1106
    • Kaneko, H.1    Igarashi, K.2    Kataoka, K.3    Miura, M.4
  • 30
    • 17444451603 scopus 로고    scopus 로고
    • Hypertonic saline enhances expression of phosphorylated histone H2AX after irradiation
    • Reitsema T.J., Banath J.P., MacPhail S.H., and Olive P.L. Hypertonic saline enhances expression of phosphorylated histone H2AX after irradiation. Radiat. Res. 161 (2004) 402-408
    • (2004) Radiat. Res. , vol.161 , pp. 402-408
    • Reitsema, T.J.1    Banath, J.P.2    MacPhail, S.H.3    Olive, P.L.4
  • 31
    • 24944486385 scopus 로고    scopus 로고
    • DNA-PK is responsible for enhanced phosphorylation of histone H2AX under hypertonic conditions
    • Reitsema T., Klokov D., Banath J.P., and Olive P.L. DNA-PK is responsible for enhanced phosphorylation of histone H2AX under hypertonic conditions. DNA Repair (Amst) 4 (2005) 1172-1181
    • (2005) DNA Repair (Amst) , vol.4 , pp. 1172-1181
    • Reitsema, T.1    Klokov, D.2    Banath, J.P.3    Olive, P.L.4
  • 32
    • 0035948802 scopus 로고    scopus 로고
    • Identification of genotoxic stress in human cells by fluorescent monitoring of p53 expression
    • Quinones A., and Rainov N.G. Identification of genotoxic stress in human cells by fluorescent monitoring of p53 expression. Mutat. Res. 494 (2001) 73-85
    • (2001) Mutat. Res. , vol.494 , pp. 73-85
    • Quinones, A.1    Rainov, N.G.2
  • 33
    • 0036317090 scopus 로고    scopus 로고
    • High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter
    • Sohn T.A., Bansal R., Su G.H., Murphy K.M., and Kern S.E. High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter. Carcinogenesis 23 (2002) 949-957
    • (2002) Carcinogenesis , vol.23 , pp. 949-957
    • Sohn, T.A.1    Bansal, R.2    Su, G.H.3    Murphy, K.M.4    Kern, S.E.5
  • 35
    • 23844432842 scopus 로고    scopus 로고
    • Histone H2AX phosphorylation after cell irradiation with UV-B: relationship to cell cycle phase and induction of apoptosis
    • Halicka H.D., Huang X., Traganos F., King M.A., Dai W., and Darzynkiewicz Z. Histone H2AX phosphorylation after cell irradiation with UV-B: relationship to cell cycle phase and induction of apoptosis. Cell Cycle 4 (2005) 339-345
    • (2005) Cell Cycle , vol.4 , pp. 339-345
    • Halicka, H.D.1    Huang, X.2    Traganos, F.3    King, M.A.4    Dai, W.5    Darzynkiewicz, Z.6
  • 36
    • 85078513502 scopus 로고    scopus 로고
    • DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis
    • Huang X., Traganos F., and Darzynkiewicz Z. DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis. Cell Cycle 2 (2003) 614-619
    • (2003) Cell Cycle , vol.2 , pp. 614-619
    • Huang, X.1    Traganos, F.2    Darzynkiewicz, Z.3
  • 37
    • 0037981413 scopus 로고    scopus 로고
    • Cell cycle-dependent expression of phosphorylated histone H2AX: reduced expression in unirradiated but not X-irradiated G1-phase cells
    • MacPhail S.H., Banath J.P., Yu Y., Chu E., and Olive P.L. Cell cycle-dependent expression of phosphorylated histone H2AX: reduced expression in unirradiated but not X-irradiated G1-phase cells. Radiat. Res. 159 (2003) 759-767
    • (2003) Radiat. Res. , vol.159 , pp. 759-767
    • MacPhail, S.H.1    Banath, J.P.2    Yu, Y.3    Chu, E.4    Olive, P.L.5
  • 38
    • 1842577548 scopus 로고    scopus 로고
    • Evidence for an S-phase checkpoint regulating DNA replication after heat shock: a review
    • Iliakis G., Krieg T., Guan J., Wang Y., and Leeper D. Evidence for an S-phase checkpoint regulating DNA replication after heat shock: a review. Int. J. Hyperthermia 20 (2004) 240-249
    • (2004) Int. J. Hyperthermia , vol.20 , pp. 240-249
    • Iliakis, G.1    Krieg, T.2    Guan, J.3    Wang, Y.4    Leeper, D.5
  • 39
    • 0022471768 scopus 로고
    • Effects of hyperthermia on radiation-induced chromosome breakage and loss in excision repair deficient Drosophila melanogaster
    • Mittler S. Effects of hyperthermia on radiation-induced chromosome breakage and loss in excision repair deficient Drosophila melanogaster. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 50 (1986) 225-230
    • (1986) Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. , vol.50 , pp. 225-230
    • Mittler, S.1
  • 40
    • 0024988212 scopus 로고
    • Effects of hyperthermia on the repair of radiation-induced DNA single- and double-strand breaks in DNA double-strand break repair-deficient and repair-proficient cell lines
    • Iliakis G., Seaner R., and Okayasu R. Effects of hyperthermia on the repair of radiation-induced DNA single- and double-strand breaks in DNA double-strand break repair-deficient and repair-proficient cell lines. Int. J. Hyperthermia 6 (1990) 813-833
    • (1990) Int. J. Hyperthermia , vol.6 , pp. 813-833
    • Iliakis, G.1    Seaner, R.2    Okayasu, R.3
  • 41
    • 0034699151 scopus 로고    scopus 로고
    • Genotoxicity evaluation of heat shock in gold fish (Carassius auratus)
    • Anitha B., Chandra N., Gopinath P.M., and Durairaj G. Genotoxicity evaluation of heat shock in gold fish (Carassius auratus). Mutat. Res. 469 (2000) 1-8
    • (2000) Mutat. Res. , vol.469 , pp. 1-8
    • Anitha, B.1    Chandra, N.2    Gopinath, P.M.3    Durairaj, G.4
  • 42
    • 0032577491 scopus 로고    scopus 로고
    • Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2
    • Kultz D., Madhany S., and Burg M.B. Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2. J. Biol. Chem. 273 (1998) 13645-13651
    • (1998) J. Biol. Chem. , vol.273 , pp. 13645-13651
    • Kultz, D.1    Madhany, S.2    Burg, M.B.3
  • 43
    • 0039594736 scopus 로고    scopus 로고
    • Protection of renal inner medullary epithelial cells from apoptosis by hypertonic stress-induced p53 activation
    • Dmitrieva N., Kultz D., Michea L., Ferraris J., and Burg M. Protection of renal inner medullary epithelial cells from apoptosis by hypertonic stress-induced p53 activation. J. Biol. Chem. 275 (2000) 18243-18247
    • (2000) J. Biol. Chem. , vol.275 , pp. 18243-18247
    • Dmitrieva, N.1    Kultz, D.2    Michea, L.3    Ferraris, J.4    Burg, M.5
  • 44
    • 0027136048 scopus 로고
    • Ionizing radiation induces two forms of interphase chromosome breaks in Chinese hamster ovary cells that rejoin with different kinetics and show different sensitivity to treatment in hypertonic medium or beta-araA
    • Okayasu R., and Iliakis G. Ionizing radiation induces two forms of interphase chromosome breaks in Chinese hamster ovary cells that rejoin with different kinetics and show different sensitivity to treatment in hypertonic medium or beta-araA. Radiat. Res. 136 (1993) 262-270
    • (1993) Radiat. Res. , vol.136 , pp. 262-270
    • Okayasu, R.1    Iliakis, G.2
  • 45
    • 0025082472 scopus 로고
    • Correlation between non-repairable DNA lesions and fixation of cell damage by hypertonic solutions in Chinese hamster cells
    • Kosaka T., Kaneko I., and Koide F. Correlation between non-repairable DNA lesions and fixation of cell damage by hypertonic solutions in Chinese hamster cells. Int. J. Radiat. Biol. 58 (1990) 417-425
    • (1990) Int. J. Radiat. Biol. , vol.58 , pp. 417-425
    • Kosaka, T.1    Kaneko, I.2    Koide, F.3
  • 46
    • 0035852695 scopus 로고    scopus 로고
    • Hyperosmolality in the form of elevated NaCl but not urea causes DNA damage in murine kidney cells
    • Kultz D., and Chakravarty D. Hyperosmolality in the form of elevated NaCl but not urea causes DNA damage in murine kidney cells. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 1999-2004
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 1999-2004
    • Kultz, D.1    Chakravarty, D.2
  • 47
    • 10444280006 scopus 로고    scopus 로고
    • Hypertonic stress response
    • Dmitrieva N.I., and Burg M.B. Hypertonic stress response. Mutat. Res. 569 (2005) 65-74
    • (2005) Mutat. Res. , vol.569 , pp. 65-74
    • Dmitrieva, N.I.1    Burg, M.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.