-
2
-
-
2542536710
-
Disappearance of the telomere dysfunction-induced stress response in fully senescent cells
-
DOI 10.1158/0008-5472.CAN-04-0453
-
CJ Bakkenist R Drissi J Wu MB Kastan JS Dome 2004 Disappearance of the telomere dysfunction-induced stress response in fully senescent cells Cancer Res 64 3748 3752 10.1158/0008-5472.CAN-04-0453 15172978 (Pubitemid 38697281)
-
(2004)
Cancer Research
, vol.64
, Issue.11
, pp. 3748-3752
-
-
Bakkenist, C.J.1
Drissi, R.2
Wu, J.3
Kastan, M.B.4
Dome, J.S.5
-
3
-
-
4944234150
-
Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines
-
DOI 10.1158/0008-5472.CAN-04-1433
-
JP Banath SH Macphail PL Olive 2004 Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines Cancer Res 64 7144 7149 10.1158/0008-5472.CAN-04-1433 15466212 (Pubitemid 39331029)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7144-7149
-
-
Banath, J.P.1
MacPhail, S.H.2
Olive, P.L.3
-
4
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
DOI 10.1038/nature03482
-
J Bartkova Z Horejsi K Koed, et al. 2005 DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis Nature 434 864 870 10.1038/nature03482 15829956 (Pubitemid 40558993)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
Kramer, A.4
Tort, F.5
Zleger, K.6
Guldberg, P.7
Sehested, M.8
Nesland, J.M.9
Lukas, C.10
Orntoft, T.11
Lukas, J.12
Bartek, J.13
-
5
-
-
0037062492
-
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX
-
DOI 10.1073/pnas.122228699
-
CH Bassing KF Chua J Sekiguchi, et al. 2002 Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX Proc Natl Acad Sci USA 99 8173 8178 10.1073/pnas.122228699 12034884 (Pubitemid 34651025)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.12
, pp. 8173-8178
-
-
Bassing, C.H.1
Chua, K.F.2
Sekiguchi, J.3
Suh, H.4
Whitlow, S.R.5
Fleming, J.C.6
Monroe, B.C.7
Ciccone, D.N.8
Yan, C.9
Vlasakova, K.10
Livingston, D.M.11
Ferguson, D.O.12
Scully, R.13
Alt, F.W.14
-
6
-
-
0042991379
-
Histone H2AX: A dosage-dependent suppressor of oncogenic translocations and tumors
-
DOI 10.1016/S0092-8674(03)00566-X
-
CH Bassing H Suh DO Ferguson, et al. 2003 Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors Cell 114 359 370 10.1016/S0092-8674(03)00566-X 12914700 (Pubitemid 36962934)
-
(2003)
Cell
, vol.114
, Issue.3
, pp. 359-370
-
-
Bassing, C.H.1
Suh, H.2
Ferguson, D.O.3
Chua, K.F.4
Manis, J.5
Eckersdorff, M.6
Gleason, M.7
Bronson, R.8
Lee, C.9
Alt, F.W.10
-
7
-
-
70249114048
-
Microscopic imaging of DNA repair foci in irradiated normal tissues
-
(in press)
-
Bhogal N, Jalali F, Bristow RG (2009). Microscopic imaging of DNA repair foci in irradiated normal tissues. Int J Radiat Biol (in press)
-
(2009)
Int J Radiat Biol
-
-
Bhogal, N.1
Jalali, F.2
Bristow, R.G.3
-
8
-
-
33947167388
-
Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability
-
DOI 10.1038/sj.emboj.7601574, PII 7601574
-
M Bogliolo A Lyakhovich E Callen, et al. 2007 Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability EMBO J 26 1340 1351 10.1038/sj.emboj.7601574 17304220 (Pubitemid 46398698)
-
(2007)
EMBO Journal
, vol.26
, Issue.5
, pp. 1340-1351
-
-
Bogliolo, M.1
Lyakhovich, A.2
Callen, E.3
Castella, M.4
Cappelli, E.5
Ramirez, M.J.6
Creus, A.7
Marcos, R.8
Kalb, R.9
Neveling, K.10
Schindler, D.11
Surralles, J.12
-
10
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
DOI 10.1126/science.1069398
-
A Celeste S Petersen PJ Romanienko, et al. 2002 Genomic instability in mice lacking histone H2AX Science 296 922 927 10.1126/science.1069398 11934988 (Pubitemid 34464900)
-
(2002)
Science
, vol.296
, Issue.5569
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
Sedelnikova, O.A.6
Reina-San-Martin, B.7
Coppola, V.8
Meffre, E.9
Difilippantonio, M.J.10
Redon, C.11
Pilch, D.R.12
Olaru, A.13
Eckhaus, M.14
Camerini-Otero, R.D.15
Tessarollo, L.16
Livak, F.17
Manova, K.18
Bonner, W.M.19
Nussenzweig, M.C.20
Nussenzweig, A.21
more..
-
11
-
-
0042991383
-
H2AX haploinsufficiency modifies genomic stability and tumor susceptibility
-
DOI 10.1016/S0092-8674(03)00567-1
-
A Celeste S Difilippantonio MJ Difilippantonio, et al. 2003 H2AX haploinsufficiency modifies genomic stability and tumor susceptibility Cell 114 371 383 10.1016/S0092-8674(03)00567-1 12914701 (Pubitemid 36962935)
-
(2003)
Cell
, vol.114
, Issue.3
, pp. 371-383
-
-
Celeste, A.1
Difilippantonio, S.2
Difilippantonio, M.J.3
Fernandez-Capetillo, O.4
Pilch, D.R.5
Sedelnikova, O.A.6
Eckhaus, M.7
Ried, T.8
Bonner, W.M.9
Nussenzweig, A.10
-
12
-
-
0037711771
-
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
-
DOI 10.1038/ncb1004
-
A Celeste O Fernandez-Capetillo MJ Kruhlak, et al. 2003 Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks Nat Cell Biol 5 675 679 10.1038/ncb1004 12792649 (Pubitemid 36818091)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.7
, pp. 675-679
-
-
Celeste, A.1
Fernandez-Capetillo, O.2
Kruhlak, M.J.3
Pilch, D.R.4
Staudt, D.W.5
Lee, A.6
Bonner, R.F.7
Bonner, W.M.8
Nussenzweig, A.9
-
13
-
-
0034644473
-
Signaling to chromatin through histone modifications
-
10.1016/S0092-8674(00)00118-5 11057899
-
P Cheung CD Allis P Sassone-Corsi 2000 Signaling to chromatin through histone modifications Cell 103 263 271 10.1016/S0092-8674(00)00118-5 11057899
-
(2000)
Cell
, vol.103
, pp. 263-271
-
-
Cheung, P.1
Allis, C.D.2
Sassone-Corsi, P.3
-
14
-
-
33645053801
-
Lysine residues in N-terminal and C-terminal regions of human histone H2A are targets for biotinylation by biotinidase
-
10.1016/j.jnutbio.2005.05.003 16109483
-
YC Chew G Camporeale N Kothapalli G Sarath J Zempleni 2006 Lysine residues in N-terminal and C-terminal regions of human histone H2A are targets for biotinylation by biotinidase J Nutr Biochem 17 225 233 10.1016/j.jnutbio. 2005.05.003 16109483
-
(2006)
J Nutr Biochem
, vol.17
, pp. 225-233
-
-
Chew, Y.C.1
Camporeale, G.2
Kothapalli, N.3
Sarath, G.4
Zempleni, J.5
-
15
-
-
63849187827
-
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
-
10.1038/nature07849 19234442
-
PJ Cook BG Ju F Telese X Wang CK Glass MG Rosenfeld 2009 Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions Nature 458 591 596 10.1038/nature07849 19234442
-
(2009)
Nature
, vol.458
, pp. 591-596
-
-
Cook, P.J.1
Ju, B.G.2
Telese, F.3
Wang, X.4
Glass, C.K.5
Rosenfeld, M.G.6
-
16
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
DOI 10.1038/nature02118
-
F d'Adda di Fagagna PM Reaper L Clay-Farrace, et al. 2003 A DNA damage checkpoint response in telomere-initiated senescence Nature 426 194 198 10.1038/nature02118 14608368 (Pubitemid 37442589)
-
(2003)
Nature
, vol.426
, Issue.6963
, pp. 194-198
-
-
D'Adda Di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
17
-
-
25444502873
-
Immunofluorescence detection of clustered γ-H2AX foci induced by HZE-particle radiation
-
DOI 10.1667/RR3431.1
-
N Desai E Davis P O'Neill M Durante FA Cucinotta H Wu 2005 Immunofluorescence detection of clustered gamma-H2AX foci induced by HZE-particle radiation Radiat Res 164 518 522 10.1667/RR3431.1 16187760 (Pubitemid 41368929)
-
(2005)
Radiation Research
, vol.164
, Issue.4
, pp. 518-522
-
-
Desai, N.1
Davis, E.2
O'Neill, P.3
Durante, M.4
Cucinotta, F.A.5
Wu, H.6
-
18
-
-
33746618049
-
GammaH2AX as a checkpoint maintenance signal
-
16855385
-
M Downey D Durocher 2006 gammaH2AX as a checkpoint maintenance signal Cell Cycle 5 1376 1381 16855385
-
(2006)
Cell Cycle
, vol.5
, pp. 1376-1381
-
-
Downey, M.1
Durocher, D.2
-
19
-
-
0036903037
-
2-M checkpoint activation by histone H2AX and 53BP1
-
DOI 10.1038/ncb884
-
O Fernandez-Capetillo HT Chen A Celeste, et al. 2002 DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1 Nat Cell Biol 4 993 997 10.1038/ncb884 12447390 (Pubitemid 35469431)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.12
, pp. 993-997
-
-
Fernandez-Capetillo, O.1
Chen, H.-T.2
Celeste, A.3
Ward, I.4
Romanienko, P.J.5
Morales, J.C.6
Naka, K.7
Xia, Z.8
Camerini-Otero, R.D.9
Motoyama, N.10
Carpenter, P.B.11
Bonner, W.M.12
Chen, J.13
Nussenzweig, A.14
-
20
-
-
0141740426
-
Focusing on foci: H2AX and the recruitment of DNA-damage response factors
-
12963833
-
O Fernandez-Capetillo A Celeste A Nussenzweig 2003 Focusing on foci: H2AX and the recruitment of DNA-damage response factors Cell Cycle 2 426 427 12963833
-
(2003)
Cell Cycle
, vol.2
, pp. 426-427
-
-
Fernandez-Capetillo, O.1
Celeste, A.2
Nussenzweig, A.3
-
21
-
-
3242880238
-
H2AX: The histone guardian of the genome
-
DOI 10.1016/j.dnarep.2004.03.024, PII S1568786404000837
-
O Fernandez-Capetillo A Lee M Nussenzweig A Nussenzweig 2004 H2AX: the histone guardian of the genome DNA Repair (Amst) 3 959 967 10.1016/j.dnarep. 2004.03.024 (Pubitemid 38997938)
-
(2004)
DNA Repair
, vol.3
, Issue.8-9
, pp. 959-967
-
-
Fernandez-Capetillo, O.1
Lee, A.2
Nussenzweig, M.3
Nussenzweig, A.4
-
22
-
-
33750692709
-
γH2AX and its role in DNA double-strand break repair
-
DOI 10.1139/O06-072
-
J Fillingham MC Keogh NJ Krogan 2006 GammaH2AX and its role in DNA double-strand break repair Biochem Cell Biol 84 568 577 10.1139/O06-072 16936829 (Pubitemid 44703660)
-
(2006)
Biochemistry and Cell Biology
, vol.84
, Issue.4
, pp. 568-577
-
-
Fillingham, J.1
Keogh, M.-C.2
Krogan, N.J.3
-
23
-
-
0038820065
-
Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes
-
DOI 10.1074/jbc.M300198200
-
T Furuta H Takemura ZY Liao, et al. 2003 Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes J Biol Chem 278 20303 20312 10.1074/jbc.M300198200 12660252 (Pubitemid 36799229)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.22
, pp. 20303-20312
-
-
Furuta, T.1
Takemura, H.2
Liao, Z.-Y.3
Aune, G.J.4
Redon, C.5
Sedelnikova, O.A.6
Pilch, D.R.7
Rogakou, E.P.8
Celeste, A.9
Chen, H.T.10
Nussenzweig, A.11
Aladjem, M.I.12
Bonner, W.M.13
Pommier, Y.14
-
24
-
-
27144486122
-
Novel genotoxicity assays identify norethindrone to activate p53 and phosphorylate H2AX
-
DOI 10.1093/carcin/bgi132
-
E Gallmeier JM Winter SC Cunningham SR Kahn SE Kern 2005 Novel genotoxicity assays identify norethindrone to activate p53 and phosphorylate H2AX Carcinogenesis 26 1811 1820 10.1093/carcin/bgi132 15905198 (Pubitemid 41487998)
-
(2005)
Carcinogenesis
, vol.26
, Issue.10
, pp. 1811-1820
-
-
Gallmeier, E.1
Winter, J.M.2
Cunningham, S.C.3
Kahn, S.R.4
Kern, S.E.5
-
25
-
-
0037099468
-
Histone modification and replacement in chromatin activation
-
DOI 10.1101/gad.1013902
-
MG Goll TH Bestor 2002 Histone modification and replacement in chromatin activation Genes Dev 16 1739 1742 10.1101/gad.1013902 12130533 (Pubitemid 34803889)
-
(2002)
Genes and Development
, vol.16
, Issue.14
, pp. 1739-1742
-
-
Goll, M.G.1
Bestor, T.H.2
-
26
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
DOI 10.1038/nature03485
-
VG Gorgoulis LV Vassiliou P Karakaidos, et al. 2005 Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions Nature 434 907 913 10.1038/nature03485 15829965 (Pubitemid 40559004)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.-V.F.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
Venere, M.7
DiTullio Jr., R.A.8
Kastrinakis, N.G.9
Levy, B.10
Kletsas, D.11
Yoneta, A.12
Herlyn, M.13
Kittas, C.14
Halazonetis, T.D.15
-
27
-
-
66749174811
-
DNA damage response as a biomarker in treatment of leukemias
-
19411853
-
HD Halicka MF Ozkaynak O Levendoglu-Tugal, et al. 2009 DNA damage response as a biomarker in treatment of leukemias Cell Cycle 8 1720 1724 19411853
-
(2009)
Cell Cycle
, vol.8
, pp. 1720-1724
-
-
Halicka, H.D.1
Ozkaynak, M.F.2
Levendoglu-Tugal, O.3
-
28
-
-
33846913205
-
Short-term culture and γH2AX flow cytometry determine differences in individual radiosensitivity in human peripheral T lymphocytes
-
DOI 10.1002/em.20273
-
K Hamasaki K Imai K Nakachi N Takahashi Y Kodama Y Kusunoki 2007 Short-term culture and gammaH2AX flow cytometry determine differences in individual radiosensitivity in human peripheral T lymphocytes Environ Mol Mutagen 48 38 47 10.1002/em.20273 17163504 (Pubitemid 46238557)
-
(2007)
Environmental and Molecular Mutagenesis
, vol.48
, Issue.1
, pp. 38-47
-
-
Hamasaki, K.1
Imai, K.2
Nakachi, K.3
Takahashi, N.4
Kodama, Y.5
Kusunoki, Y.6
-
29
-
-
36148951013
-
H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase
-
DOI 10.1093/carcin/bgm157
-
S Hanasoge M Ljungman 2007 H2AX phosphorylation after UV-irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase Carcinogenesis 28 11 2298 2304 10.1093/carcin/bgm157 17615256 (Pubitemid 350111588)
-
(2007)
Carcinogenesis
, vol.28
, Issue.11
, pp. 2298-2304
-
-
Hanasoge, S.1
Ljungman, M.2
-
30
-
-
9744271049
-
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
-
Hickson I, Zhao Y, Richardson CJ et al (2004) Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res 64:9152-9159
-
(2004)
Cancer Res
, vol.64
, pp. 9152-9159
-
-
Hickson, I.1
Zhao, Y.2
Richardson, C.J.3
-
31
-
-
63449133609
-
Phase i study of sequence-selective minor groove DNA binding agent SJG-136 in patients with advanced solid tumors
-
10.1158/1078-0432.CCR-08-1315 19276288
-
D Hochhauser T Meyer VJ Spanswick, et al. 2009 Phase I study of sequence-selective minor groove DNA binding agent SJG-136 in patients with advanced solid tumors Clin Cancer Res 15 2140 2147 10.1158/1078-0432.CCR-08-1315 19276288
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2140-2147
-
-
Hochhauser, D.1
Meyer, T.2
Spanswick, V.J.3
-
32
-
-
0034503870
-
Cellular senescence mechanisms independent of telomere shortening and telomerase: Other barriers to cell immortalization and carcinogenesis
-
I Horikawa T Yawata JC Barrett 2000 Cellular senescence mechanisms independent of telomere shortening and telomerase: other barriers to cell immortalization and carcinogenesis J Anti-Aging Med 3 373 382
-
(2000)
J Anti-Aging Med
, vol.3
, pp. 373-382
-
-
Horikawa, I.1
Yawata, T.2
Barrett, J.C.3
-
33
-
-
24144467509
-
In Situ visualization of DSBs to assess the extranuclear/extracellular effects induced by low-dose α-particle irradiation
-
DOI 10.1667/RR3415.1
-
B Hu W Han L Wu, et al. 2005 In situ visualization of DSBs to assess the extranuclear/extracellular effects induced by low-dose alpha-particle irradiation Radiat Res 164 286 291 10.1667/RR3415.1 16137201 (Pubitemid 41233782)
-
(2005)
Radiation Research
, vol.164
, Issue.3
, pp. 286-291
-
-
Hu, B.1
Man, W.2
Wu, L.3
Feng, H.4
Liu, X.5
Zhang, L.6
Xu, A.7
Hei, T.K.8
Yu, Z.9
-
34
-
-
85078513502
-
DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis
-
14504478
-
X Huang F Traganos Z Darzynkiewicz 2003 DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis Cell Cycle 2 614 619 14504478
-
(2003)
Cell Cycle
, vol.2
, pp. 614-619
-
-
Huang, X.1
Traganos, F.2
Darzynkiewicz, Z.3
-
35
-
-
58149188894
-
Detection of histone H2AX phosphorylation on Ser-139 as an indicator of DNA damage (DNA double-strand breaks)
-
Huang X, Halicka HD, Darzynkiewicz Z (2004) Detection of histone H2AX phosphorylation on Ser-139 as an indicator of DNA damage (DNA double-strand breaks). Curr Protoc Cytom Chapter 7: Unit 7 27
-
(2004)
Curr Protoc Cytom Chapter 7: Unit 7 27
-
-
Huang, X.1
Halicka, H.D.2
Darzynkiewicz, Z.3
-
36
-
-
23844518979
-
Cytometric assessment of DNA damage in relation to cell cycle phase and apoptosis
-
DOI 10.1111/j.1365-2184.2005.00344.x
-
X Huang HD Halicka F Traganos T Tanaka A Kurose Z Darzynkiewicz 2005 Cytometric assessment of DNA damage in relation to cell cycle phase and apoptosis Cell Prolif 38 223 243 10.1111/j.1365-2184.2005.00344.x 16098182 (Pubitemid 41176576)
-
(2005)
Cell Proliferation
, vol.38
, Issue.4
, pp. 223-243
-
-
Huang, X.1
Halicka, H.D.2
Traganos, F.3
Tanaka, T.4
Kurose, A.5
Darzynkiewicz, Z.6
-
37
-
-
34248158282
-
Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status
-
DOI 10.1158/0008-5472.CAN-06-4328
-
CR Hunt RK Pandita A Laszlo, et al. 2007 Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status Cancer Res 67 3010 3017 10.1158/0008-5472.CAN-06- 4328 17409407 (Pubitemid 46724837)
-
(2007)
Cancer Research
, vol.67
, Issue.7
, pp. 3010-3017
-
-
Hunt, C.R.1
Pandita, R.K.2
Laszlo, A.3
Higashikubo, R.4
Agarwal, M.5
Kitamura, T.6
Gupta, A.7
Rief, N.8
Horikoshi, N.9
Baskaran, R.10
Lee, J.-H.11
Lobrich, M.12
Paull, T.T.13
Roti Roti, J.L.14
Pandita, T.K.15
-
38
-
-
34547615725
-
Water soluble fraction of solar-simulated light-exposed crude oil generates phosphorylation of histone H2AX in human skin cells under UVA exposure
-
DOI 10.1002/em.20292
-
Y Ibuki T Toyooka J Shirahata T Ohura R Goto 2007 Water soluble fraction of solar-simulated light-exposed crude oil generates phosphorylation of histone H2AX in human skin cells under UVA exposure Environ Mol Mutagen 48 430 439 10.1002/em.20292 17372987 (Pubitemid 47207001)
-
(2007)
Environmental and Molecular Mutagenesis
, vol.48
, Issue.6
, pp. 430-439
-
-
Ibuki, Y.1
Toyooka, T.2
Shirahata, J.3
Ohura, T.4
Goto, R.5
-
39
-
-
35148894396
-
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics
-
DOI 10.1128/MCB.00579-07
-
T Ikura S Tashiro A Kakino, et al. 2007 DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics Mol Cell Biol 27 7028 7040 10.1128/MCB.00579-07 17709392 (Pubitemid 47549742)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.20
, pp. 7028-7040
-
-
Ikura, T.1
Tashiro, S.2
Kakino, A.3
Shima, H.4
Jacob, N.5
Amunugama, R.6
Yoder, K.7
Izumi, S.8
Kuraoka, I.9
Tanaka, K.10
Kimura, H.11
Ikura, M.12
Nishikubo, S.13
Ito, T.14
Muto, A.15
Miyagawa, K.16
Takeda, S.17
Fishel, R.18
Igarashi, K.19
Kamiya, K.20
more..
-
40
-
-
33846090789
-
Accumulation of senescent cells in mitotic tissue of aging primates
-
DOI 10.1016/j.mad.2006.11.008, PII S0047637406002417, Functional Genomics of Aging III
-
JC Jeyapalan M Ferreira JM Sedivy U Herbig 2007 Accumulation of senescent cells in mitotic tissue of aging primates Mech Ageing Dev 128 36 44 10.1016/j.mad.2006.11.008 17116315 (Pubitemid 46073058)
-
(2007)
Mechanisms of Ageing and Development
, vol.128
, Issue.1
, pp. 36-44
-
-
Jeyapalan, J.C.1
Ferreira, M.2
Sedivy, J.M.3
Herbig, U.4
-
41
-
-
11844259424
-
Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression
-
DOI 10.1128/MCB.25.2.661-670.2005
-
J Kang D Ferguson H Song C Bassing M Eckersdorff FW Alt Y Xu 2005 Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression Mol Cell Biol 25 661 670 10.1128/MCB.25.2.661- 670.2005 15632067 (Pubitemid 40096587)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.2
, pp. 661-670
-
-
Kang, J.1
Ferguson, D.2
Song, H.3
Bassing, C.4
Eckersdorff, M.5
Alt, F.W.6
Xu, Y.7
-
42
-
-
33646790488
-
γ-H2AX as a therapeutic target for improving the efficacy of radiation therapy
-
DOI 10.2174/156800906776842957
-
J Kao MT Milano A Javaheri MC Garofalo SJ Chmura RR Weichselbaum SJ Kron 2006 gamma-H2AX as a therapeutic target for improving the efficacy of radiation therapy Curr Cancer Drug Targets 6 197 205 10.2174/156800906776842957 16712457 (Pubitemid 43764740)
-
(2006)
Current Cancer Drug Targets
, vol.6
, Issue.3
, pp. 197-205
-
-
Kao, J.1
Milano, M.T.2
Javaheri, A.3
Garofalo, M.C.4
Chmura, S.J.5
Weichselbaum, R.R.6
Kron, S.J.7
-
43
-
-
33646562250
-
Modulation of cellular radiation responses by histone deacetylase inhibitors
-
DOI 10.1038/sj.onc.1209417, PII 1209417
-
TC Karagiannis A El-Osta 2006 Modulation of cellular radiation responses by histone deacetylase inhibitors Oncogene 25 3885 3893 10.1038/sj.onc.1209417 16462761 (Pubitemid 43990743)
-
(2006)
Oncogene
, vol.25
, Issue.28
, pp. 3885-3893
-
-
Karagiannis, T.C.1
El-Osta, A.2
-
44
-
-
70450224944
-
Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia: A preclinical and phase i trial of the farnesyltransferase inhibitor tipifarnib (R115777, Zarnestra) combined with etoposide
-
Karp JE, Flatten K, Feldman EJ et al (2008) Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia: a preclinical and phase I trial of the farnesyltransferase inhibitor tipifarnib (R115777, Zarnestra) combined with etoposide. Blood
-
(2008)
Blood
-
-
Karp, J.E.1
Flatten, K.2
Feldman, E.J.3
-
45
-
-
66749158695
-
Genotoxicity of 3, 6-dinitrobenzo[e]pyrene, a novel mutagen in ambient air and surface soil, in mammalian cells in vitro and in vivo
-
10.1093/mutage/gep007 19273466
-
M Kawanishi T Watanabe S Hagio, et al. 2009 Genotoxicity of 3, 6-dinitrobenzo[e]pyrene, a novel mutagen in ambient air and surface soil, in mammalian cells in vitro and in vivo Mutagenesis 24 3 279 284 10.1093/mutage/gep007 19273466
-
(2009)
Mutagenesis
, vol.24
, Issue.3
, pp. 279-284
-
-
Kawanishi, M.1
Watanabe, T.2
Hagio, S.3
-
46
-
-
0032776303
-
Molecular interaction map of the mammalian cell cycle control and DNA repair systems
-
10436023
-
KW Kohn 1999 Molecular interaction map of the mammalian cell cycle control and DNA repair systems Mol Biol Cell 10 2703 2734 10436023
-
(1999)
Mol Biol Cell
, vol.10
, pp. 2703-2734
-
-
Kohn, K.W.1
-
47
-
-
52049090800
-
Tissue-specific DNA-PK-dependent H2AX phosphorylation and gamma-H2AX elimination after X-irradiation in vivo
-
10.1016/j.bbrc.2008.08.095 18755145
-
M Koike J Sugasawa M Yasuda A Koike 2008 Tissue-specific DNA-PK-dependent H2AX phosphorylation and gamma-H2AX elimination after X-irradiation in vivo Biochem Biophys Res Commun 376 52 55 10.1016/j.bbrc.2008.08.095 18755145
-
(2008)
Biochem Biophys Res Commun
, vol.376
, pp. 52-55
-
-
Koike, M.1
Sugasawa, J.2
Yasuda, M.3
Koike, A.4
-
49
-
-
68449103051
-
DNA double-strand breaks and their repair in blood lymphocytes of patients undergoing angiographic procedures
-
10.1097/RLI.0b013e3181a654a5 19448553
-
MA Kuefner S Grudzenski SA Schwab, et al. 2009 DNA double-strand breaks and their repair in blood lymphocytes of patients undergoing angiographic procedures Invest Radiol 44 8 440 446 10.1097/RLI.0b013e3181a654a5 19448553
-
(2009)
Invest Radiol
, vol.44
, Issue.8
, pp. 440-446
-
-
Kuefner, M.A.1
Grudzenski, S.2
Schwab, S.A.3
-
50
-
-
0041762654
-
Induction of DNA damage responses by adozelesin is S phase-specific and dependent on active replication forks
-
12533671
-
JS Liu SR Kuo TA Beerman T Melendy 2003 Induction of DNA damage responses by adozelesin is S phase-specific and dependent on active replication forks Molecular Cancer Therapeutics 2 41 47 12533671
-
(2003)
Molecular Cancer Therapeutics
, vol.2
, pp. 41-47
-
-
Liu, J.S.1
Kuo, S.R.2
Beerman, T.A.3
Melendy, T.4
-
51
-
-
34047270774
-
Histone H2AX is a mediator of gastrointestinal stromal tumor cell apoptosis following treatment with imatinib mesylate
-
DOI 10.1158/0008-5472.CAN-06-3497
-
Y Liu M Tseng SA Perdreau, et al. 2007 Histone H2AX is a mediator of gastrointestinal stromal tumor cell apoptosis following treatment with imatinib mesylate Cancer Res 67 2685 2692 10.1158/0008-5472.CAN-06-3497 17363589 (Pubitemid 46548956)
-
(2007)
Cancer Research
, vol.67
, Issue.6
, pp. 2685-2692
-
-
Liu, Y.1
Tseng, M.2
Perdreau, S.A.3
Rossi, F.4
Antonescu, C.5
Besmer, P.6
Fletcher, J.A.7
Duensing, S.8
Duensing, A.9
-
52
-
-
33745487368
-
Cell Apoptosis: Requirement of H2AX in DNA Ladder Formation, but Not for the Activation of Caspase-3
-
DOI 10.1016/j.molcel.2006.05.023, PII S1097276506003388
-
C Lu F Zhu YY Cho, et al. 2006 Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3 Mol cell 23 121 132 10.1016/j.molcel.2006.05.023 16818236 (Pubitemid 43963445)
-
(2006)
Molecular Cell
, vol.23
, Issue.1
, pp. 121-132
-
-
Lu, C.1
Zhu, F.2
Cho, Y.-Y.3
Tang, F.4
Zykova, T.5
Ma, W.-y.6
Bode, A.M.7
Dong, Z.8
-
53
-
-
33750870356
-
50-Hertz electromagnetic fields induce gammaH2AX foci formation in mouse preimplantation embryos in vitro
-
DOI 10.1095/biolreprod.106.052241
-
Q Luo J Yang QL Zeng XM Zhu YL Qian HF Huang 2006 50-Hertz electromagnetic fields induce gammaH2AX foci formation in mouse preimplantation embryos in vitro Biol Reprod 75 673 680 10.1095/biolreprod.106.052241 16855210 (Pubitemid 44720386)
-
(2006)
Biology of Reproduction
, vol.75
, Issue.5
, pp. 673-680
-
-
Luo, Q.1
Yang, J.2
Zeng, Q.-L.3
Zhu, X.-M.4
Qian, Y.-L.5
Huang, H.-F.6
-
54
-
-
34248159902
-
New roads to FA/BRCA pathway: H2AX
-
17471025
-
A Lyakhovich J Surralles 2007 New roads to FA/BRCA pathway: H2AX Cell Cycle 6 1019 1023 17471025
-
(2007)
Cell Cycle
, vol.6
, pp. 1019-1023
-
-
Lyakhovich, A.1
Surralles, J.2
-
55
-
-
33750092260
-
Candidate protein biodosimeters of human exposure to ionizing radiation
-
DOI 10.1080/09553000600930103, PII R46U0788L74W395K
-
F Marchetti MA Coleman IM Jones AJ Wyrobek 2006 Candidate protein biodosimeters of human exposure to ionizing radiation Int J Radiat Biol 82 605 639 10.1080/09553000600930103 17050475 (Pubitemid 44581946)
-
(2006)
International Journal of Radiation Biology
, vol.82
, Issue.9
, pp. 605-639
-
-
Marchetti, F.1
Coleman, M.A.2
Jones, I.M.3
Wyrobek, A.J.4
-
56
-
-
25844432196
-
Microwaves from GSM mobile telephones affect 53BP1 and γ-H2AX foci in human lymphocytes from hypersensitive and healthy persons
-
DOI 10.1289/ehp.7561
-
E Markova L Hillert L Malmgren BR Persson IY Belyaev 2005 Microwaves from GSM mobile telephones affect 53BP1 and gamma-H2AX foci in human lymphocytes from hypersensitive and healthy persons Environ Health Perspect 113 1172 1177 16140623 (Pubitemid 41387655)
-
(2005)
Environmental Health Perspectives
, vol.113
, Issue.9
, pp. 1172-1177
-
-
Markova, E.1
Hillert, L.2
Malmgren, L.3
Persson, B.R.R.4
Belyaev, I.Y.5
-
57
-
-
65549160933
-
Exposure of HepG2 cells to low levels of PAH-containing extracts from contaminated soils results in unpredictable genotoxic stress responses
-
10.1002/em.20486 19306413
-
A Mattsson S Lundstedt U Stenius 2009 Exposure of HepG2 cells to low levels of PAH-containing extracts from contaminated soils results in unpredictable genotoxic stress responses Environ Mol Mutagen 50 337 348 10.1002/em.20486 19306413
-
(2009)
Environ Mol Mutagen
, vol.50
, pp. 337-348
-
-
Mattsson, A.1
Lundstedt, S.2
Stenius, U.3
-
59
-
-
33745198661
-
Techniques for γ-H2AX Detection
-
DOI 10.1016/S0076-6879(05)09014-2, PII S0076687905090142
-
A Nakamura OA Sedelnikova C Redon, et al. 2006 Techniques for gamma-H2AX detection Methods Enzymol 409 236 250 10.1016/S0076-6879(05)09014-2 16793405 (Pubitemid 43912290)
-
(2006)
Methods in Enzymology
, vol.409
, pp. 236-250
-
-
Nakamura, A.1
Sedelnikova, O.A.2
Redon, C.3
Pilch, D.R.4
Sinogeeva, N.I.5
Shroff, R.6
Lichten, M.7
Bonner, W.M.8
-
61
-
-
34250818190
-
Genetic variation in H2AFX contributes to risk of non-Hodgkin lymphoma
-
DOI 10.1158/1055-9965.EPI-06-0639
-
KL Novik JJ Spinelli AC Macarthur, et al. 2007 Genetic variation in H2AFX contributes to risk of non-Hodgkin lymphoma Cancer Epidemiol Biomarkers Prev 16 1098 1106 10.1158/1055-9965.EPI-06-0639 17548670 (Pubitemid 46984944)
-
(2007)
Cancer Epidemiology Biomarkers and Prevention
, vol.16
, Issue.6
, pp. 1098-1106
-
-
Novik, K.L.1
Spinelli, J.J.2
MacArthur, A.C.3
Shumansky, K.4
Sipahimalani, P.5
Leach, S.6
Lai, A.7
Connors, J.M.8
Gascoyne, R.D.9
Gallagher, R.P.10
Brooks-Wilson, A.R.11
-
62
-
-
0942278942
-
Phosphorylation of histone H2AX as a measure of radiosensitivity
-
14751500
-
PL Olive JP Banath 2004 Phosphorylation of histone H2AX as a measure of radiosensitivity Int J Radiat Oncol Biol Phys 58 331 335 14751500
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 331-335
-
-
Olive, P.L.1
Banath, J.P.2
-
63
-
-
3442889371
-
Phosphorylated histone H2AX in spheroids, tumors, and tissues of mice exposed to etoposide and 3-amino-1,2,4-benzotriazine-1,3-dioxide
-
DOI 10.1158/0008-5472.CAN-04-0729
-
PL Olive JP Banath LT Sinnott 2004 Phosphorylated histone H2AX in spheroids, tumors, and tissues of mice exposed to etoposide and 3-amino-1, 2, 4-benzotriazine-1, 3-dioxide Cancer Res 64 5363 5369 10.1158/0008-5472.CAN-04- 0729 15289343 (Pubitemid 39006557)
-
(2004)
Cancer Research
, vol.64
, Issue.15
, pp. 5363-5369
-
-
Olive, P.L.1
Banath, J.P.2
Sinnott, L.T.3
-
64
-
-
34250358742
-
Loss of distal 11q is associated with DNA repair deficiency and reduced sensitivity to ionizing radiation in head and neck squamous cell carcinoma
-
DOI 10.1002/gcc.20462
-
RA Parikh JS White X Huang, et al. 2007 Loss of distal 11q is associated with DNA repair deficiency and reduced sensitivity to ionizing radiation in head and neck squamous cell carcinoma Genes, Chromosomes Cancer 46 761 775 10.1002/gcc.20462 17492757 (Pubitemid 46912347)
-
(2007)
Genes Chromosomes and Cancer
, vol.46
, Issue.8
, pp. 761-775
-
-
Parikh, R.A.1
White, J.S.2
Huang, X.3
Schoppy, D.W.4
Baysal, B.E.5
Baskaran, R.6
Bakkenist, C.J.7
Saunders, W.S.8
Hsu, L.-C.9
Romkes, M.10
Gollin, S.M.11
-
65
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
DOI 10.1016/S0960-9822(00)00610-2
-
TT Paull EP Rogakou V Yamazaki CU Kirchgessner M Gellert WM Bonner 2000 A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage Curr Biol 10 886 895 10.1016/S0960-9822(00)00610-2 10959836 (Pubitemid 30647617)
-
(2000)
Current Biology
, vol.10
, Issue.15
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
66
-
-
0003539105
-
-
Lippincott, Williams & Wilkins Philadelphia
-
Perez CA, Brady LW, Halperin EC, Schmidt-Ullrich RK (2004) Principles and practice of radiation oncology. Lippincott, Williams & Wilkins, Philadelphia
-
(2004)
Principles and Practice of Radiation Oncology
-
-
Perez, C.A.1
Brady, L.W.2
Halperin, E.C.3
Schmidt-Ullrich, R.K.4
-
67
-
-
17644377918
-
Mismatch repair proteins are activators of toxic responses to chromium-DNA damage
-
DOI 10.1128/MCB.25.9.3596-3607.2005
-
E Peterson-Roth M Reynolds G Quievryn A Zhitkovich 2005 Mismatch repair proteins are activators of toxic responses to chromium-DNA damage Mol Cell Biol 25 3596 3607 10.1128/MCB.25.9.3596-3607.2005 15831465 (Pubitemid 40559566)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.9
, pp. 3596-3607
-
-
Peterson-Roth, E.1
Reynolds, M.2
Quievryn, G.3
Zhitkovich, A.4
-
69
-
-
33746503104
-
Impaired elimination of DNA double-strand break-containing lymphocytes in ataxia telangiectasia and Nijmegen breakage syndrome
-
DOI 10.1016/j.dnarep.2006.05.002, PII S1568786406001236
-
P Porcedda V Turinetto E Lantelme, et al. 2006 Impaired elimination of DNA double-strand break-containing lymphocytes in ataxia telangiectasia and Nijmegen breakage syndrome DNA Repair (Amst) 5 904 913 10.1016/j.dnarep.2006.05. 002 (Pubitemid 44137485)
-
(2006)
DNA Repair
, vol.5
, Issue.8
, pp. 904-913
-
-
Porcedda, P.1
Turinetto, V.2
Lantelme, E.3
Fontanella, E.4
Chrzanowska, K.5
Ragona, R.6
De Marchi, M.7
Delia, D.8
Giachino, C.9
-
70
-
-
67349217443
-
Two-tier analysis of histone H2AX phosphorylation allows the identification of Ataxia Telangiectasia heterozygotes
-
10.1016/j.radonc.2008.12.010 19167771
-
P Porcedda V Turinetto L Orlando, et al. 2009 Two-tier analysis of histone H2AX phosphorylation allows the identification of Ataxia Telangiectasia heterozygotes Radiother Oncol 92 133 137 10.1016/j.radonc.2008.12.010 19167771
-
(2009)
Radiother Oncol
, vol.92
, pp. 133-137
-
-
Porcedda, P.1
Turinetto, V.2
Orlando, L.3
-
71
-
-
0242500374
-
Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements
-
DOI 10.1038/sj.leu.2402883
-
CH Pui JM Chessells B Camitta, et al. 2003 Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements Leukemia 17 700 706 10.1038/sj.leu.2402883 12682627 (Pubitemid 36519366)
-
(2003)
Leukemia
, vol.17
, Issue.4
, pp. 700-706
-
-
Pui, C.-H.1
Chessells, J.M.2
Camitta, B.3
Baruchel, A.4
Biondi, A.5
Boyett, J.M.6
Carroll, A.7
Eden, O.B.8
Evans, W.E.9
Gadner, H.10
Harbott, J.11
Harms, D.O.12
Harrison, C.J.13
Harrison, P.L.14
Heerema, N.15
Janka-Schaub, G.16
Kamps, W.17
Masera, G.18
Pullen, J.19
Raimondi, S.C.20
Richards, S.21
Riehm, H.22
Sallan, S.23
Sather, H.24
Shuster, J.25
Silverman, L.B.26
Valsecchi, M.G.27
Vilmer, E.28
Zhou, Y.29
Gaynon, P.S.30
Schrappe, M.31
more..
-
74
-
-
62949181960
-
Gamma-H2AX as a biomarker of DNA damage induced by ionizing radiation in human peripheral blood lymphocytes and artificial skin
-
10.1016/j.asr.2008.10.011
-
C Redon JS Dickey WM Bonner O Sedelnikova 2009 gamma-H2AX as a biomarker of DNA damage induced by ionizing radiation in human peripheral blood lymphocytes and artificial skin Adv Space Res 43 1171 1178 10.1016/j.asr.2008. 10.011
-
(2009)
Adv Space Res
, vol.43
, pp. 1171-1178
-
-
Redon, C.1
Dickey, J.S.2
Bonner, W.M.3
Sedelnikova, O.4
-
75
-
-
48549086606
-
Ulcerative colitis is a disease of accelerated colon aging: Evidence from telomere attrition and DNA damage
-
10.1053/j.gastro.2008.04.008 18519043
-
RA Risques LA Lai TA Brentnall, et al. 2008 Ulcerative colitis is a disease of accelerated colon aging: evidence from telomere attrition and DNA damage Gastroenterology 135 410 418 10.1053/j.gastro.2008.04.008 18519043
-
(2008)
Gastroenterology
, vol.135
, pp. 410-418
-
-
Risques, R.A.1
Lai, L.A.2
Brentnall, T.A.3
-
77
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
DOI 10.1083/jcb.146.5.905
-
EP Rogakou C Boon C Redon WM Bonner 1999 Megabase chromatin domains involved in DNA double-strand breaks in vivo J Cell Biol 146 905 916 10.1083/jcb.146.5.905 10477747 (Pubitemid 29430435)
-
(1999)
Journal of Cell Biology
, vol.146
, Issue.5
, pp. 905-915
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
78
-
-
0030069762
-
11q23 rearrangements in acute leukemia
-
8558942
-
JE Rubnitz FG Behm JR Downing 1996 11q23 rearrangements in acute leukemia Leukemia 10 74 82 8558942
-
(1996)
Leukemia
, vol.10
, pp. 74-82
-
-
Rubnitz, J.E.1
Behm, F.G.2
Downing, J.R.3
-
79
-
-
65549129613
-
Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin
-
Savic V, Yin B, Maas NL et al (2009) Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. Molecular Cell 34:298-310
-
(2009)
Molecular Cell
, vol.34
, pp. 298-310
-
-
Savic, V.1
Yin, B.2
Maas, N.L.3
-
80
-
-
33845651212
-
GammaH2AX in cancer cells: A potential biomarker for cancer diagnostics, prediction and recurrence
-
17172873
-
OA Sedelnikova WM Bonner 2006 GammaH2AX in cancer cells: a potential biomarker for cancer diagnostics, prediction and recurrence Cell Cycle 5 2909 2913 17172873
-
(2006)
Cell Cycle
, vol.5
, pp. 2909-2913
-
-
Sedelnikova, O.A.1
Bonner, W.M.2
-
86
-
-
35148834590
-
Gamma-H2AX in bystander cells: Not just a radiation-triggered event, a cellular response to stress mediated by intercellular communication
-
17881892
-
MV Sokolov JS Dickey WM Bonner OA Sedelnikova 2007 gamma-H2AX in bystander cells: not just a radiation-triggered event, a cellular response to stress mediated by intercellular communication Cell Cycle 6 2210 2212 17881892
-
(2007)
Cell Cycle
, vol.6
, pp. 2210-2212
-
-
Sokolov, M.V.1
Dickey, J.S.2
Bonner, W.M.3
Sedelnikova, O.A.4
-
87
-
-
38149028414
-
Copy number alterations of the H2AFX gene in sporadic breast cancer patients
-
10.1016/j.cancergencyto.2007.09.024 18206537
-
N Srivastava S Gochhait P Gupta RN Bamezai 2008 Copy number alterations of the H2AFX gene in sporadic breast cancer patients Cancer Genet Cytogenet 180 121 128 10.1016/j.cancergencyto.2007.09.024 18206537
-
(2008)
Cancer Genet Cytogenet
, vol.180
, pp. 121-128
-
-
Srivastava, N.1
Gochhait, S.2
Gupta, P.3
Bamezai, R.N.4
-
88
-
-
1942538492
-
ATM and DNA-PK Function Redundantly to Phosphorylate H2AX after Exposure to Ionizing Radiation
-
DOI 10.1158/0008-5472.CAN-03-3207
-
T Stiff M O'Driscoll N Rief K Iwabuchi M Lobrich PA Jeggo 2004 ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation Cancer Res 64 2390 2396 10.1158/0008-5472.CAN-03-3207 15059890 (Pubitemid 38523891)
-
(2004)
Cancer Research
, vol.64
, Issue.7
, pp. 2390-2396
-
-
Stiff, T.1
O'Driscoll, M.2
Rief, N.3
Iwabuchi, K.4
Lobrich, M.5
Jeggo, P.A.6
-
89
-
-
33845715977
-
ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling
-
DOI 10.1038/sj.emboj.7601446, PII 7601446
-
T Stiff SA Walker K Cerosaletti, et al. 2006 ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling EMBO J 25 5775 5782 10.1038/sj.emboj.7601446 17124492 (Pubitemid 44967761)
-
(2006)
EMBO Journal
, vol.25
, Issue.24
, pp. 5775-5782
-
-
Stiff, T.1
Walker, S.A.2
Cerosaletti, K.3
Goodarzi, A.A.4
Petermann, E.5
Concannon, P.6
O'Driscoll, M.7
Jeggo, P.A.8
-
90
-
-
0033916381
-
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
-
DOI 10.1136/gut.47.2.268
-
Y Takagi M Futamura K Yamaguchi S Aoki T Takahashi S Saji 2000 Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers Gut 47 268 271 10.1136/gut.47.2.268 10896920 (Pubitemid 30489772)
-
(2000)
Gut
, vol.47
, Issue.2
, pp. 268-271
-
-
Takagi, Y.1
Futamura, M.2
Yamaguchi, K.3
Aoki, S.4
Takahashi, T.5
Saji, S.6
-
91
-
-
0346457085
-
Histone H2AX Phosphorylation as a Predictor of Radiosensitivity and Target for Radiotherapy
-
DOI 10.1074/jbc.M310030200
-
N Taneja M Davis JS Choy MA Beckett R Singh SJ Kron RR Weichselbaum 2004 Histone H2AX phosphorylation as a predictor of radiosensitivity and target for radiotherapy J Biol Chem 279 2273 2280 10.1074/jbc.M310030200 14561744 (Pubitemid 38084500)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.3
, pp. 2273-2280
-
-
Taneja, N.1
Davis, M.2
Choy, J.S.3
Beckett, M.A.4
Singh, R.5
Kron, S.J.6
Weichselbaum, R.R.7
-
92
-
-
0027279628
-
Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations
-
DOI 10.1056/NEJM199309233291302
-
MJ Thirman HJ Gill RC Burnett, et al. 1993 Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations N Engl J Med 329 909 914 10.1056/NEJM199309233291302 8361504 (Pubitemid 23275271)
-
(1993)
New England Journal of Medicine
, vol.329
, Issue.13
, pp. 909-914
-
-
Thirman, M.J.1
Gill, H.J.2
Burnett, R.C.3
Mbangkollo, D.4
McCabe, N.R.5
Kobayashi, H.6
Ziemin-Van Der Poel, S.7
Kaneko, Y.8
Morgan, R.9
Sandberg, A.A.10
Chaganti, R.S.K.11
Larson, R.A.12
Le Beau, M.M.13
Diaz, M.O.14
Rowley, J.D.15
-
93
-
-
27744439306
-
Coexposure to benzo[a]pyrene and UVA induces phosphorylation of histone H2AX
-
DOI 10.1016/j.febslet.2005.10.015, PII S0014579305012561
-
T Toyooka Y Ibuki 2005 Co-exposure to benzo[a]pyrene and UVA induces phosphorylation of histone H2AX FEBS Lett 579 6338 6342 10.1016/j.febslet.2005. 10.015 16256111 (Pubitemid 41612149)
-
(2005)
FEBS Letters
, vol.579
, Issue.28
, pp. 6338-6342
-
-
Toyooka, T.1
Ibuki, Y.2
-
94
-
-
33744796789
-
New method for testing phototoxicity of polycyclic aromatic hydrocarbons
-
DOI 10.1021/es060182i
-
T Toyooka Y Ibuki 2006 New method for testing phototoxicity of polycyclic aromatic hydrocarbons Environ Sci Technol 40 3603 3608 10.1021/es060182i 16786700 (Pubitemid 43830968)
-
(2006)
Environmental Science and Technology
, vol.40
, Issue.11
, pp. 3603-3608
-
-
Toyooka, T.1
Ibuki, Y.2
-
95
-
-
67349150457
-
Cigarette sidestream smoke induces phosphorylated histone H2AX
-
19486862
-
T Toyooka Y Ibuki 2009 Cigarette sidestream smoke induces phosphorylated histone H2AX Mutat Res 676 34 40 19486862
-
(2009)
Mutat Res
, vol.676
, pp. 34-40
-
-
Toyooka, T.1
Ibuki, Y.2
-
96
-
-
10944262393
-
DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain
-
DOI 10.1016/j.molcel.2004.11.027, PII S1097276504007191
-
E Unal A Arbel-Eden U Sattler R Shroff M Lichten JE Haber D Koshland 2004 DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain Molecular cell 16 991 1002 10.1016/j.molcel.2004.11.027 15610741 (Pubitemid 40018408)
-
(2004)
Molecular Cell
, vol.16
, Issue.6
, pp. 991-1002
-
-
Unal, E.1
Arbel-Eden, A.2
Sattler, U.3
Shroff, R.4
Lichten, M.5
Haber, J.E.6
Koshland, D.7
-
97
-
-
34347407201
-
Radiation-induced γ-H2AX in mammalian cells irradiated with a synchrotron X-ray microbeam
-
DOI 10.1093/rpd/ncl434
-
N Usami M Maeda K Eguchi-Kasai H Maezawa K Kobayashi 2006 Radiation-induced gamma-H2AX in mammalian cells irradiated with a synchrotron X-ray microbeam Radiat Prot Dosimetry 122 307 309 10.1093/rpd/ncl434 17182605 (Pubitemid 47090470)
-
(2006)
Radiation Protection Dosimetry
, vol.122
, Issue.1-4
, pp. 307-309
-
-
Usami, N.1
Maeda, M.2
Eguchi-Kasai, K.3
Maezawa, H.4
Kobayashi, K.5
-
98
-
-
65149084552
-
Crosstalk between histone modifications during the DNA damage response
-
10.1016/j.tcb.2009.03.001 19342239
-
H van Attikum SM Gasser 2009 Crosstalk between histone modifications during the DNA damage response Trends Cell Biol 19 5 207 217 10.1016/j.tcb.2009.03.001 19342239
-
(2009)
Trends Cell Biol
, vol.19
, Issue.5
, pp. 207-217
-
-
Van Attikum, H.1
Gasser, S.M.2
-
99
-
-
0141619287
-
Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1
-
Veuger SJ, Curtin NJ, Richardson CJ, Smith GC, Durkacz BW (2003) Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1. Cancer Res 63:6008-6015
-
(2003)
Cancer Res
, vol.63
, pp. 6008-6015
-
-
Veuger, S.J.1
Curtin, N.J.2
Richardson, C.J.3
Smith, G.C.4
Durkacz, B.W.5
-
100
-
-
11144305946
-
Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors
-
DOI 10.1002/jcp.20141
-
H Wang M Wang H Wang W Bocker G Iliakis 2005 Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors J Cell Physiol 202 492 502 10.1002/jcp.20141 15389585 (Pubitemid 40041320)
-
(2005)
Journal of Cellular Physiology
, vol.202
, Issue.2
, pp. 492-502
-
-
Wang, H.1
Wang, M.2
Wang, H.3
Bocker, W.4
Iliakis, G.5
-
101
-
-
0035930537
-
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
-
10.1074/jbc.M009785200 11673449
-
IM Ward J Chen 2001 Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress J Biol Chem 276 47759 47762 10.1074/jbc.M009785200 11673449
-
(2001)
J Biol Chem
, vol.276
, pp. 47759-47762
-
-
Ward, I.M.1
Chen, J.2
-
102
-
-
16844370883
-
Melanoma cells express elevated levels of phosphorylated histone H2AX foci
-
DOI 10.1111/j.0022-202X.2005.23674.x
-
RL Warters PJ Adamson CD Pond SA Leachman 2005 Melanoma cells express elevated levels of phosphorylated histone H2AX foci J Invest Dermatol 124 807 817 10.1111/j.0022-202X.2005.23674.x 15816840 (Pubitemid 40489509)
-
(2005)
Journal of Investigative Dermatology
, vol.124
, Issue.4
, pp. 807-817
-
-
Warters, R.L.1
Adamson, P.J.2
Pond, C.D.3
Leachman, S.A.4
-
103
-
-
58149242430
-
WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity
-
10.1038/nature07668 19092802
-
A Xiao H Li D Shechter, et al. 2009 WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity Nature 457 57 62 10.1038/nature07668 19092802
-
(2009)
Nature
, vol.457
, pp. 57-62
-
-
Xiao, A.1
Li, H.2
Shechter, D.3
-
104
-
-
33746721468
-
Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability
-
DOI 10.1016/j.dnarep.2006.05.040, PII S1568786406001790
-
T Yu SH MacPhail JP Banath D Klokov PL Olive 2006 Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability DNA Repair (Amst) 5 935 946 10.1016/j.dnarep.2006.05. 040 (Pubitemid 44160591)
-
(2006)
DNA Repair
, vol.5
, Issue.8
, pp. 935-946
-
-
Yu, T.1
MacPhail, S.H.2
Banath, J.P.3
Klokov, D.4
Olive, P.L.5
-
105
-
-
48249121979
-
Complementary functions of ATM and H2AX in development and suppression of genomic instability
-
10.1073/pnas.0803520105 18599436
-
S Zha J Sekiguchi JW Brush CH Bassing FW Alt 2008 Complementary functions of ATM and H2AX in development and suppression of genomic instability Proc Natl Acad Sci USA 105 9302 9306 10.1073/pnas.0803520105 18599436
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 9302-9306
-
-
Zha, S.1
Sekiguchi, J.2
Brush, J.W.3
Bassing, C.H.4
Alt, F.W.5
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