Mouse lymphoma thymidine kinase gene mutation assay: Follow-up International Workshop on Genotoxicity Test Procedures, New Orleans, Louisiana, April 2000

Environmental and Molecular Mutagenesis

Volumn 40, Issue 4, 2002, Pages 292-299

  Moore, Martha M ^l   Honma, Masamitsu ^a   Clements, Julie ^b   Harrington Brock, Karen ^l   Awogi, Takumi ^c   Bolcsfoldi, George ^d   Cifone, Maria ^l   Collard, Deborah ^l   Fellows, Michael ^e   Flanders, Kathryn ^l   Gollapudi, Bhaskar ^l   Jenkinson, Peter ^f   Kirby, Paul ^l   Kirchner, Stephan ^f   Kraycer, Joann ^l   McEnaney, Stephen ^b   Muster, Wolfgang ^g   Myhr, Brian ^l   O'Donovan, Michael ^e   Oliver, Jo ^h   Ouldelhkim, Marie Claude ⁱ   Pant, Kamala ^l   Preston, Robert ^l   Riach, Colin ^j   San, Richard ^l   Shimada, Hiroyasu ^k   Stankowski Jr , Leon F ^l   more..

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b UK   (United Kingdom)

^c OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^d ASTRAZENECA R AND D   (Sweden)

^e ASTRAZENECA   (United Kingdom)

^f Safephorm Laboratories Ltd   (United Kingdom)

^g F HOFFMANN LA ROCHE LTD   (Switzerland)

^h GLAXOSMITHKLINE   (United Kingdom)

ⁱ SANOFI   (France)

^j Inveresk Research   (United Kingdom)

^k DAIICHI SANKYO CO   (Japan)

^l NONE

more..

Author keywords

[No Author keywords available]

Indexed keywords

THYMIDINE KINASE;

ARTICLE; ASSAY; CYTOTOXICITY; DATA ANALYSIS; GENE MUTATION; GENOTOXICITY; HUMAN; LYMPHOMA; MEASUREMENT; NONHUMAN; PRACTICE GUIDELINE; TOXICITY TESTING;

ANIMALS; EDUCATION; GUIDELINES; LYMPHOMA; MICE; MUTAGENICITY TESTS; MUTATION; THYMIDINE KINASE; TIME FACTORS;

EID: 0036934462     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.10122     Document Type: Article

References (6)

1. Clive D, Spector JFS. 1975. Laboratory procedure for assessing specific locus mutations at the TK locus in cultured L5178Y mouse lymphoma cells. Mutat Res 31:17-29
2. Cole J, Arlett CF, Green MHL, Lowe J, Muriel W. 1983. A comparison of the agar cloning and microtritration techniques for assaying cell survival and mutation frequency in L5178Y mouse lymphoma cells. Mutat Res 111:371-386.
3. +/- 3.7.2C) mouse lymphoma cells. Mutagenesis 1:157-167.
4. ICH. 1997. Topic S2B genotoxicity: a standard battery for genotoxicity testing of pharmaceuticals. International Conference on the Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use. Step 4 Guideline, Brussels, July 1997. (See website http://wwwifpma.irg.ichl.html)
5. Moore, MM, Honma M, Clements J, Awogi T, Bolcsfoldi G, Cole J, Gollapudi B, Harrington-Brock K, Mitchell A, Muster W, Myhr M, O'Donovan M, Ouldelhkim M-C, San R, Shimada H, Stankowski LF Jr. 2000. The mouse lymphoma thymidine kinase locus (tk) gene mutation assay: International Workshop on Genotoxicity Test Procedures (IWGTP) Workgroup Report. Environ Mol Mutagen 35:185-190.
6. -/- mouse lymphoma assay. In: Kilbey et al., editors. Handbook of mutagenicity test procedures, 2nd ed. Amsterdam: Elsevier. p 239-268.