Beyond 'furballs' and 'dumpling soups' - Towards a molecular architecture of signaling complexes and networks

FEBS Letters

Volumn 586, Issue 17, 2012, Pages 2740-2750

  Lewitzky, Marc ^a   Simister, Philip C ^a   Feller, Stephan M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Intrinsic disorder; Macromolecular crowding; Molecular architecture; Signaling complex; Signaling network; Signalosome

Indexed keywords

ADAPTOR PROTEIN; CELL PROTEIN; MESSENGER RNA; PROTEIN HUB; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; CYTOARCHITECTURE; HUMAN; INTRACELLULAR SIGNALING; MACROMOLECULE; MOLECULAR DOCKING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REVIEW; RNA TRANSLATION; STRUCTURE ANALYSIS;

ANIMALS; COMPUTATIONAL BIOLOGY; FUNGAL PROTEINS; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; MODELS, BIOLOGICAL; NEOPLASMS; PHOSPHOPROTEINS; PROTEIN INTERACTION MAPPING; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

EID: 84864616734     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.04.029     Document Type: Review

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