메뉴 건너뛰기




Volumn 33, Issue 12, 2008, Pages 592-600

The COP9 signalosome: more than a protease

Author keywords

[No Author keywords available]

Indexed keywords

COP9 PROTEASE; CULLIN; PROTEASOME; PROTEINASE; RING LIGASE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 56449094567     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2008.09.004     Document Type: Review
Times cited : (330)

References (89)
  • 1
    • 0027022309 scopus 로고
    • COP9: a new genetic locus involved in light-regulated development and gene expression in Arabidopsis
    • Wei N., and Deng X.W. COP9: a new genetic locus involved in light-regulated development and gene expression in Arabidopsis. Plant Cell 4 (1992) 1507-1518
    • (1992) Plant Cell , vol.4 , pp. 1507-1518
    • Wei, N.1    Deng, X.W.2
  • 2
    • 0037131242 scopus 로고    scopus 로고
    • Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1
    • Cope G.A., et al. Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298 (2002) 608-611
    • (2002) Science , vol.298 , pp. 608-611
    • Cope, G.A.1
  • 4
    • 0038185375 scopus 로고    scopus 로고
    • Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms
    • Liu C., et al. Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms. Genes Dev. 17 (2003) 1130-1140
    • (2003) Genes Dev. , vol.17 , pp. 1130-1140
    • Liu, C.1
  • 5
    • 37749042420 scopus 로고    scopus 로고
    • Arabidopsis eIF3e is regulated by the COP9 signalosome and has an impact on development and protein translation
    • Yahalom A., et al. Arabidopsis eIF3e is regulated by the COP9 signalosome and has an impact on development and protein translation. Plant J. 53 (2008) 300-311
    • (2008) Plant J. , vol.53 , pp. 300-311
    • Yahalom, A.1
  • 6
    • 34250215269 scopus 로고    scopus 로고
    • CIF-1, a shared subunit of the COP9/signalosome and eukaryotic initiation factor 3 complexes, regulates MEL-26 levels in the Caenorhabditis elegans embryo
    • Luke-Glaser S., et al. CIF-1, a shared subunit of the COP9/signalosome and eukaryotic initiation factor 3 complexes, regulates MEL-26 levels in the Caenorhabditis elegans embryo. Mol. Cell. Biol. 27 (2007) 4526-4540
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 4526-4540
    • Luke-Glaser, S.1
  • 7
    • 27544510262 scopus 로고    scopus 로고
    • PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes
    • Zhou C., et al. PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes. BMC Biol. 3 (2005) 14
    • (2005) BMC Biol. , vol.3 , pp. 14
    • Zhou, C.1
  • 8
    • 25444464111 scopus 로고    scopus 로고
    • Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes
    • Scheel H., and Hofmann K. Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes. BMC Bioinformatics 6 (2005) 71
    • (2005) BMC Bioinformatics , vol.6 , pp. 71
    • Scheel, H.1    Hofmann, K.2
  • 9
    • 4544304063 scopus 로고    scopus 로고
    • Crystal structure of human eIF3k, the first structure of eIF3 subunits
    • Wei Z., et al. Crystal structure of human eIF3k, the first structure of eIF3 subunits. J. Biol. Chem. 279 (2004) 34983-34990
    • (2004) J. Biol. Chem. , vol.279 , pp. 34983-34990
    • Wei, Z.1
  • 10
    • 0141706654 scopus 로고    scopus 로고
    • Structure of the Jab1/MPN domain and its implications for proteasome function
    • Tran H.J., et al. Structure of the Jab1/MPN domain and its implications for proteasome function. Biochemistry 42 (2003) 11460-11465
    • (2003) Biochemistry , vol.42 , pp. 11460-11465
    • Tran, H.J.1
  • 11
    • 19344364762 scopus 로고    scopus 로고
    • JAMM: A metalloprotease-like zinc site in the proteasome and signalosome
    • Ambroggio X.I., et al. JAMM: A metalloprotease-like zinc site in the proteasome and signalosome. PLoS Biol. 2 (2004) e2
    • (2004) PLoS Biol. , vol.2
    • Ambroggio, X.I.1
  • 12
    • 31044444461 scopus 로고    scopus 로고
    • Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p
    • Bellare P., et al. Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p. RNA 12 (2006) 292-302
    • (2006) RNA , vol.12 , pp. 292-302
    • Bellare, P.1
  • 13
    • 33847053558 scopus 로고    scopus 로고
    • Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa
    • Pena V., et al. Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa. Mol. Cell 25 (2007) 615-624
    • (2007) Mol. Cell , vol.25 , pp. 615-624
    • Pena, V.1
  • 14
    • 34250187773 scopus 로고    scopus 로고
    • The crystal structure of the human Mov34 MPN domain reveals a metal-free dimer
    • Sanches M., et al. The crystal structure of the human Mov34 MPN domain reveals a metal-free dimer. J. Mol. Biol. 370 (2007) 846-855
    • (2007) J. Mol. Biol. , vol.370 , pp. 846-855
    • Sanches, M.1
  • 15
    • 0242515762 scopus 로고    scopus 로고
    • Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex
    • Serino G., et al. Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex. Plant Cell 15 (2003) 719-731
    • (2003) Plant Cell , vol.15 , pp. 719-731
    • Serino, G.1
  • 16
    • 34249937608 scopus 로고    scopus 로고
    • An eight-subunit COP9 signalosome with an intact JAMM motif is required for fungal fruit body formation
    • Busch S., et al. An eight-subunit COP9 signalosome with an intact JAMM motif is required for fungal fruit body formation. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 8089-8094
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 8089-8094
    • Busch, S.1
  • 17
    • 33748259787 scopus 로고    scopus 로고
    • The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum
    • Rosel D., and Kimmel A.R. The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum. Eur. J. Cell Biol. 85 (2006) 1023-1034
    • (2006) Eur. J. Cell Biol. , vol.85 , pp. 1023-1034
    • Rosel, D.1    Kimmel, A.R.2
  • 18
    • 0037480420 scopus 로고    scopus 로고
    • The COP9 signalosome: regulating plant development through the control of proteolysis
    • Serino G., and Deng X.W. The COP9 signalosome: regulating plant development through the control of proteolysis. Annu. Rev. Plant Biol. 54 (2003) 165-182
    • (2003) Annu. Rev. Plant Biol. , vol.54 , pp. 165-182
    • Serino, G.1    Deng, X.W.2
  • 19
    • 0036176144 scopus 로고    scopus 로고
    • Deletion mutants in COP9/signalosome subunits in fission yeast Schizosaccharomyces pombe display distinct phenotypes
    • Mundt K.E., et al. Deletion mutants in COP9/signalosome subunits in fission yeast Schizosaccharomyces pombe display distinct phenotypes. Mol. Biol. Cell 13 (2002) 493-502
    • (2002) Mol. Biol. Cell , vol.13 , pp. 493-502
    • Mundt, K.E.1
  • 20
    • 16644385294 scopus 로고    scopus 로고
    • The Arabidopsis CSN5A and CSN5B subunits are present in distinct COP9 signalosome complexes, and mutations in their JAMM domains exhibit differential dominant negative effects on development
    • Gusmaroli G., et al. The Arabidopsis CSN5A and CSN5B subunits are present in distinct COP9 signalosome complexes, and mutations in their JAMM domains exhibit differential dominant negative effects on development. Plant Cell 16 (2004) 2984-3001
    • (2004) Plant Cell , vol.16 , pp. 2984-3001
    • Gusmaroli, G.1
  • 21
    • 0036800232 scopus 로고    scopus 로고
    • COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster
    • Oron E., et al. COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster. Development 129 (2002) 4399-4409
    • (2002) Development , vol.129 , pp. 4399-4409
    • Oron, E.1
  • 22
    • 13844259319 scopus 로고    scopus 로고
    • Small Jab1-containing subcomplex is regulated in an anchorage- and cell cycle-dependent manner, which is abrogated by ras transformation
    • Fukumoto A., et al. Small Jab1-containing subcomplex is regulated in an anchorage- and cell cycle-dependent manner, which is abrogated by ras transformation. FEBS Lett. 579 (2005) 1047-1054
    • (2005) FEBS Lett. , vol.579 , pp. 1047-1054
    • Fukumoto, A.1
  • 23
    • 11244272124 scopus 로고    scopus 로고
    • The Jab1/COP9 signalosome subcomplex is a downstream mediator of Bcr-Abl kinase activity and facilitates cell-cycle progression
    • Tomoda K., et al. The Jab1/COP9 signalosome subcomplex is a downstream mediator of Bcr-Abl kinase activity and facilitates cell-cycle progression. Blood 105 (2005) 775-783
    • (2005) Blood , vol.105 , pp. 775-783
    • Tomoda, K.1
  • 24
    • 34250663420 scopus 로고    scopus 로고
    • Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Arabidopsis Cullin3-based E3 ligases
    • Gusmaroli G., et al. Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Arabidopsis Cullin3-based E3 ligases. Plant Cell 19 (2007) 564-581
    • (2007) Plant Cell , vol.19 , pp. 564-581
    • Gusmaroli, G.1
  • 25
    • 34248162451 scopus 로고    scopus 로고
    • The nucleosome assembly activity of NAP1 is enhanced by alien
    • Eckey M., et al. The nucleosome assembly activity of NAP1 is enhanced by alien. Mol. Cell. Biol. 27 (2007) 3557-3568
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 3557-3568
    • Eckey, M.1
  • 26
    • 0037328445 scopus 로고    scopus 로고
    • Alien/CSN2 gene expression is regulated by thyroid hormone in rat brain
    • Tenbaum S.P., et al. Alien/CSN2 gene expression is regulated by thyroid hormone in rat brain. Dev. Biol. 254 (2003) 149-160
    • (2003) Dev. Biol. , vol.254 , pp. 149-160
    • Tenbaum, S.P.1
  • 27
    • 0035906430 scopus 로고    scopus 로고
    • Promotion of NEDD8-CUL1 conjugate cleavage by COP9 signalosome
    • Lyapina S., et al. Promotion of NEDD8-CUL1 conjugate cleavage by COP9 signalosome. Science 292 (2001) 1382-1385
    • (2001) Science , vol.292 , pp. 1382-1385
    • Lyapina, S.1
  • 28
    • 0035907047 scopus 로고    scopus 로고
    • Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response
    • Schwechheimer C., et al. Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response. Science 292 (2001) 1379-1382
    • (2001) Science , vol.292 , pp. 1379-1382
    • Schwechheimer, C.1
  • 29
    • 40749153516 scopus 로고    scopus 로고
    • Cullin-RING ubiquitin ligases: global regulation and activation cycles
    • Bosu D.R., and Kipreos E.T. Cullin-RING ubiquitin ligases: global regulation and activation cycles. Cell Div. 3 (2008) 7
    • (2008) Cell Div. , vol.3 , pp. 7
    • Bosu, D.R.1    Kipreos, E.T.2
  • 30
    • 44949242505 scopus 로고    scopus 로고
    • Regulation of Cullin RING Ligases
    • Hotton S.K., and Callis J. Regulation of Cullin RING Ligases. Annu. Rev. Plant Biol. 59 (2008) 467-489
    • (2008) Annu. Rev. Plant Biol. , vol.59 , pp. 467-489
    • Hotton, S.K.1    Callis, J.2
  • 31
    • 0037117417 scopus 로고    scopus 로고
    • The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1
    • Yang X., et al. The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1. Curr. Biol. 12 (2002) 667-672
    • (2002) Curr. Biol. , vol.12 , pp. 667-672
    • Yang, X.1
  • 32
    • 0038491277 scopus 로고    scopus 로고
    • NEDP1, a highly conserved cysteine protease that deNEDDylates cullins
    • Mendoza H.M., et al. NEDP1, a highly conserved cysteine protease that deNEDDylates cullins. J. Biol. Chem. 278 (2003) 25637-25643
    • (2003) J. Biol. Chem. , vol.278 , pp. 25637-25643
    • Mendoza, H.M.1
  • 33
    • 0043208977 scopus 로고    scopus 로고
    • DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1
    • Wu K., et al. DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1. J. Biol. Chem. 278 (2003) 28882-28891
    • (2003) J. Biol. Chem. , vol.278 , pp. 28882-28891
    • Wu, K.1
  • 34
    • 32044442093 scopus 로고    scopus 로고
    • Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels
    • Cope G.A., and Deshaies R.J. Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels. BMC Biochem. 7 (2006) 1
    • (2006) BMC Biochem. , vol.7 , pp. 1
    • Cope, G.A.1    Deshaies, R.J.2
  • 35
    • 33845939310 scopus 로고    scopus 로고
    • The COP9 signalosome regulates Skp2 levels and proliferation of human cells
    • Denti S., et al. The COP9 signalosome regulates Skp2 levels and proliferation of human cells. J. Biol. Chem. 281 (2006) 32188-32196
    • (2006) J. Biol. Chem. , vol.281 , pp. 32188-32196
    • Denti, S.1
  • 36
    • 38849097142 scopus 로고    scopus 로고
    • Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability
    • Peth A., et al. Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability. BMC Biochem. 8 (2007) 27
    • (2007) BMC Biochem. , vol.8 , pp. 27
    • Peth, A.1
  • 37
    • 43749123835 scopus 로고    scopus 로고
    • CSN5 binds to misfolded CFTR and promotes its degradation
    • Tanguy G., et al. CSN5 binds to misfolded CFTR and promotes its degradation. Biochim. Biophys. Acta 1783 (2008) 1189-1199
    • (2008) Biochim. Biophys. Acta , vol.1783 , pp. 1189-1199
    • Tanguy, G.1
  • 38
    • 33645127077 scopus 로고    scopus 로고
    • Genetic regulators of large-scale transcriptional signatures in cancer
    • Adler A.S., et al. Genetic regulators of large-scale transcriptional signatures in cancer. Nat. Genet. 38 (2006) 421-430
    • (2006) Nat. Genet. , vol.38 , pp. 421-430
    • Adler, A.S.1
  • 39
    • 33644776551 scopus 로고    scopus 로고
    • Jab1 is a specificity factor for E2F1-induced apoptosis
    • Hallstrom T.C., and Nevins J.R. Jab1 is a specificity factor for E2F1-induced apoptosis. Genes Dev. 20 (2006) 613-623
    • (2006) Genes Dev. , vol.20 , pp. 613-623
    • Hallstrom, T.C.1    Nevins, J.R.2
  • 40
    • 29944435762 scopus 로고    scopus 로고
    • The emerging role of the COP9 signalosome in cancer
    • Richardson K.S., and Zundel W. The emerging role of the COP9 signalosome in cancer. Mol. Cancer Res. 3 (2005) 645-653
    • (2005) Mol. Cancer Res. , vol.3 , pp. 645-653
    • Richardson, K.S.1    Zundel, W.2
  • 41
    • 1842632327 scopus 로고    scopus 로고
    • Distinct aerobic and hypoxic mechanisms of HIF-α regulation by CSN5
    • Bemis L., et al. Distinct aerobic and hypoxic mechanisms of HIF-α regulation by CSN5. Genes Dev. 18 (2004) 739-744
    • (2004) Genes Dev. , vol.18 , pp. 739-744
    • Bemis, L.1
  • 42
    • 40349087136 scopus 로고    scopus 로고
    • Roles for CSN5 in control of p53/MDM2 activities
    • Zhang X.C., et al. Roles for CSN5 in control of p53/MDM2 activities. J. Cell. Biochem. 103 (2008) 1219-1230
    • (2008) J. Cell. Biochem. , vol.103 , pp. 1219-1230
    • Zhang, X.C.1
  • 43
    • 18944391961 scopus 로고    scopus 로고
    • CSN5/Jab1 is involved in ligand-dependent degradation of estrogen receptor α by the proteasome
    • Callige M., et al. CSN5/Jab1 is involved in ligand-dependent degradation of estrogen receptor α by the proteasome. Mol. Cell. Biol. 25 (2005) 4349-4358
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 4349-4358
    • Callige, M.1
  • 44
    • 34447252157 scopus 로고    scopus 로고
    • Jab1 mediates protein degradation of the Rad9-Rad1-Hus1 checkpoint complex
    • Huang J., et al. Jab1 mediates protein degradation of the Rad9-Rad1-Hus1 checkpoint complex. J. Mol. Biol. 371 (2007) 514-527
    • (2007) J. Mol. Biol. , vol.371 , pp. 514-527
    • Huang, J.1
  • 45
    • 33749559162 scopus 로고    scopus 로고
    • Jab1 mediates cytoplasmic localization and degradation of West Nile virus capsid protein
    • Oh W., et al. Jab1 mediates cytoplasmic localization and degradation of West Nile virus capsid protein. J. Biol. Chem. 281 (2006) 30166-30174
    • (2006) J. Biol. Chem. , vol.281 , pp. 30166-30174
    • Oh, W.1
  • 46
    • 33745218066 scopus 로고    scopus 로고
    • Jab1 induces the cytoplasmic localization and degradation of p53 in coordination with Hdm2
    • Oh W., et al. Jab1 induces the cytoplasmic localization and degradation of p53 in coordination with Hdm2. J. Biol. Chem. 281 (2006) 17457-17465
    • (2006) J. Biol. Chem. , vol.281 , pp. 17457-17465
    • Oh, W.1
  • 47
    • 0033545636 scopus 로고    scopus 로고
    • Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
    • Tomoda K., et al. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1. Nature 398 (1999) 160-165
    • (1999) Nature , vol.398 , pp. 160-165
    • Tomoda, K.1
  • 48
    • 5644256911 scopus 로고    scopus 로고
    • Multiple functions of Jab1 are required for early embryonic development and growth potential in mice
    • Tomoda K., et al. Multiple functions of Jab1 are required for early embryonic development and growth potential in mice. J. Biol. Chem. 279 (2004) 43013-43018
    • (2004) J. Biol. Chem. , vol.279 , pp. 43013-43018
    • Tomoda, K.1
  • 49
    • 39549120409 scopus 로고    scopus 로고
    • Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development
    • Panattoni M., et al. Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development. J. Exp. Med. 205 (2008) 465-477
    • (2008) J. Exp. Med. , vol.205 , pp. 465-477
    • Panattoni, M.1
  • 50
    • 39049134967 scopus 로고    scopus 로고
    • CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression
    • Adler A.S., et al. CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression. Cancer Res. 68 (2008) 506-515
    • (2008) Cancer Res. , vol.68 , pp. 506-515
    • Adler, A.S.1
  • 51
    • 33645216339 scopus 로고    scopus 로고
    • Cu14A and DDB1 associate with Skp2 to target p27(Kip1) for proteolysis involving the COP9 signalosome
    • Bondar T., et al. Cu14A and DDB1 associate with Skp2 to target p27(Kip1) for proteolysis involving the COP9 signalosome. Mol. Cell. Biol. 26 (2006) 2531-2539
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2531-2539
    • Bondar, T.1
  • 52
    • 0036472506 scopus 로고    scopus 로고
    • The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis
    • Bech-Otschir D., et al. The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis. J. Cell Sci. 115 (2002) 467-473
    • (2002) J. Cell Sci. , vol.115 , pp. 467-473
    • Bech-Otschir, D.1
  • 53
    • 0141557809 scopus 로고    scopus 로고
    • Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death
    • Lykke-Andersen K., et al. Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death. Mol. Cell. Biol. 23 (2003) 6790-6797
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 6790-6797
    • Lykke-Andersen, K.1
  • 54
    • 35548940309 scopus 로고    scopus 로고
    • COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence
    • Menon S., et al. COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence. Nat. Immunol. 8 (2007) 1236-1245
    • (2007) Nat. Immunol. , vol.8 , pp. 1236-1245
    • Menon, S.1
  • 55
    • 46749125432 scopus 로고    scopus 로고
    • The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability
    • Dohmann E.M., et al. The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability. Development 135 (2008) 2013-2022
    • (2008) Development , vol.135 , pp. 2013-2022
    • Dohmann, E.M.1
  • 56
    • 22344458341 scopus 로고    scopus 로고
    • The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex
    • He Q., et al. The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex. Genes Dev. 19 (2005) 1518-1531
    • (2005) Genes Dev. , vol.19 , pp. 1518-1531
    • He, Q.1
  • 57
    • 0042665894 scopus 로고    scopus 로고
    • The COP9 signalosome is an essential regulator of development in the filamentous fungus Aspergillus nidulans
    • Busch S., et al. The COP9 signalosome is an essential regulator of development in the filamentous fungus Aspergillus nidulans. Mol. Microbiol. 49 (2003) 717-730
    • (2003) Mol. Microbiol. , vol.49 , pp. 717-730
    • Busch, S.1
  • 58
    • 0033518297 scopus 로고    scopus 로고
    • The COP9/signalosome complex is conserved in fission yeast and has a role in S phase
    • Mundt K.E., et al. The COP9/signalosome complex is conserved in fission yeast and has a role in S phase. Curr. Biol. 9 (1999) 1427-1430
    • (1999) Curr. Biol. , vol.9 , pp. 1427-1430
    • Mundt, K.E.1
  • 59
    • 33644503868 scopus 로고    scopus 로고
    • Identification of pathways regulating cell size and cell-cycle progression by RNAi
    • Bjorklund M., et al. Identification of pathways regulating cell size and cell-cycle progression by RNAi. Nature 439 (2006) 1009-1013
    • (2006) Nature , vol.439 , pp. 1009-1013
    • Bjorklund, M.1
  • 60
    • 18944367474 scopus 로고    scopus 로고
    • Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3
    • Yoneda-Kato N., et al. Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3. EMBO J. 24 (2005) 1739-1749
    • (2005) EMBO J. , vol.24 , pp. 1739-1749
    • Yoneda-Kato, N.1
  • 61
    • 34249018249 scopus 로고    scopus 로고
    • Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression
    • Oron E., et al. Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression. Mol. Syst. Biol. 3 (2007) 108
    • (2007) Mol. Syst. Biol. , vol.3 , pp. 108
    • Oron, E.1
  • 62
    • 0037648338 scopus 로고    scopus 로고
    • Skp2 regulates Myc protein stability and activity
    • Kim S.Y., et al. Skp2 regulates Myc protein stability and activity. Mol. Cell 11 (2003) 1177-1188
    • (2003) Mol. Cell , vol.11 , pp. 1177-1188
    • Kim, S.Y.1
  • 63
    • 12444264823 scopus 로고    scopus 로고
    • The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription
    • von der Lehr N., et al. The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription. Mol. Cell 11 (2003) 1189-1200
    • (2003) Mol. Cell , vol.11 , pp. 1189-1200
    • von der Lehr, N.1
  • 64
    • 43049100743 scopus 로고    scopus 로고
    • An Arabidopsis F-box protein acts as a transcriptional co-factor to regulate floral development
    • Chae E., et al. An Arabidopsis F-box protein acts as a transcriptional co-factor to regulate floral development. Development 135 (2008) 1235-1245
    • (2008) Development , vol.135 , pp. 1235-1245
    • Chae, E.1
  • 65
    • 0038414526 scopus 로고    scopus 로고
    • The COP9 signalosome interacts with SCF UFO and participates in Arabidopsis flower development
    • Wang X., et al. The COP9 signalosome interacts with SCF UFO and participates in Arabidopsis flower development. Plant Cell 15 (2003) 1071-1082
    • (2003) Plant Cell , vol.15 , pp. 1071-1082
    • Wang, X.1
  • 66
    • 34247182609 scopus 로고    scopus 로고
    • Retinoblastoma protein regulation by the COP9 signalosome
    • Ullah Z., et al. Retinoblastoma protein regulation by the COP9 signalosome. Mol. Biol. Cell 18 (2007) 1179-1186
    • (2007) Mol. Biol. Cell , vol.18 , pp. 1179-1186
    • Ullah, Z.1
  • 67
    • 34548512294 scopus 로고    scopus 로고
    • Alien inhibits E2F1 gene expression and cell proliferation
    • Tenbaum S.P., et al. Alien inhibits E2F1 gene expression and cell proliferation. Biochim. Biophys. Acta 1773 (2007) 1447-1454
    • (2007) Biochim. Biophys. Acta , vol.1773 , pp. 1447-1454
    • Tenbaum, S.P.1
  • 68
    • 40549121948 scopus 로고    scopus 로고
    • Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome
    • Menon S., et al. Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome. BMC Biochem. 9 (2008) 1
    • (2008) BMC Biochem. , vol.9 , pp. 1
    • Menon, S.1
  • 69
    • 0037509859 scopus 로고    scopus 로고
    • The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage
    • Groisman R., et al. The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. Cell 113 (2003) 357-367
    • (2003) Cell , vol.113 , pp. 357-367
    • Groisman, R.1
  • 70
    • 17044378618 scopus 로고    scopus 로고
    • Ddb1 controls genome stability and meiosis in fission yeast
    • Holmberg C., et al. Ddb1 controls genome stability and meiosis in fission yeast. Genes Dev. 19 (2005) 853-862
    • (2005) Genes Dev. , vol.19 , pp. 853-862
    • Holmberg, C.1
  • 71
    • 0242525214 scopus 로고    scopus 로고
    • Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint
    • Higa L.A.A., et al. Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint. Nat. Cell Biol. 5 (2003) 1008-1015
    • (2003) Nat. Cell Biol. , vol.5 , pp. 1008-1015
    • Higa, L.A.A.1
  • 72
    • 33746830878 scopus 로고    scopus 로고
    • Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate
    • Bornstein G., et al. Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 11515-11520
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 11515-11520
    • Bornstein, G.1
  • 73
    • 34250333052 scopus 로고    scopus 로고
    • The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis
    • da Silva Correia J., et al. The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis. J. Biol. Chem. 282 (2007) 12557-12565
    • (2007) J. Biol. Chem. , vol.282 , pp. 12557-12565
    • da Silva Correia, J.1
  • 74
    • 38649109469 scopus 로고    scopus 로고
    • The COP9 signalosome-mediated deneddylation is stimulated by caspases during apoptosis
    • Hetfeld B.K.J., et al. The COP9 signalosome-mediated deneddylation is stimulated by caspases during apoptosis. Apoptosis 13 (2008) 187-195
    • (2008) Apoptosis , vol.13 , pp. 187-195
    • Hetfeld, B.K.J.1
  • 75
    • 33846559388 scopus 로고    scopus 로고
    • COP9 signalosome subunit 5 (CSN5/Jab1) regulates the development of the Drosophila immune system: effects on Cactus, Dorsal and hematopoiesis
    • Harari-Steinberg O., et al. COP9 signalosome subunit 5 (CSN5/Jab1) regulates the development of the Drosophila immune system: effects on Cactus, Dorsal and hematopoiesis. Genes Cells 12 (2007) 183-195
    • (2007) Genes Cells , vol.12 , pp. 183-195
    • Harari-Steinberg, O.1
  • 76
    • 0036178019 scopus 로고    scopus 로고
    • CSN1 N-terminal-dependent activity is required for Arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: a structure-function study of CSN1 subunit of COP9 signalosome
    • Wang X., et al. CSN1 N-terminal-dependent activity is required for Arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: a structure-function study of CSN1 subunit of COP9 signalosome. Mol. Biol. Cell 13 (2002) 646-655
    • (2002) Mol. Biol. Cell , vol.13 , pp. 646-655
    • Wang, X.1
  • 77
    • 27144492877 scopus 로고    scopus 로고
    • Loss of the constitutive photomorphogenic9 signalosome subunit 5 is sufficient to cause the cop/det/fus mutant phenotype in Arabidopsis
    • Dohmann E.M., et al. Loss of the constitutive photomorphogenic9 signalosome subunit 5 is sufficient to cause the cop/det/fus mutant phenotype in Arabidopsis. Plant Cell 17 (2005) 1967-1978
    • (2005) Plant Cell , vol.17 , pp. 1967-1978
    • Dohmann, E.M.1
  • 78
    • 0037509945 scopus 로고    scopus 로고
    • Fission yeast COP9/signalosome suppresses cullin acivity through recruitment of the deubiquitylating enzyme Ubp12p
    • Zhou C., et al. Fission yeast COP9/signalosome suppresses cullin acivity through recruitment of the deubiquitylating enzyme Ubp12p. Mol. Cell 11 (2003) 927-938
    • (2003) Mol. Cell , vol.11 , pp. 927-938
    • Zhou, C.1
  • 79
    • 32544438880 scopus 로고    scopus 로고
    • The csnD/csnE signalosome genes are involved in the Aspergillus nidulans DNA damage response
    • Lima J.F., et al. The csnD/csnE signalosome genes are involved in the Aspergillus nidulans DNA damage response. Genetics 171 (2005) 1003-1015
    • (2005) Genetics , vol.171 , pp. 1003-1015
    • Lima, J.F.1
  • 80
    • 0038329328 scopus 로고    scopus 로고
    • The COP9 signalosome promotes degradation of cyclin E during early Drosophila oogenesis
    • Doronkin S., et al. The COP9 signalosome promotes degradation of cyclin E during early Drosophila oogenesis. Dev. Cell 4 (2003) 699-710
    • (2003) Dev. Cell , vol.4 , pp. 699-710
    • Doronkin, S.1
  • 81
    • 39749142226 scopus 로고    scopus 로고
    • Cop9 signalosome subunit 8 (CSN8) is essential for Drosophila development
    • Oren-Giladi P., et al. Cop9 signalosome subunit 8 (CSN8) is essential for Drosophila development. Genes Cells 13 (2008) 221-231
    • (2008) Genes Cells , vol.13 , pp. 221-231
    • Oren-Giladi, P.1
  • 82
    • 0141669190 scopus 로고    scopus 로고
    • COP9 signalosome subunit 3 (Csn3) is essential for maintenance of cell proliferation in the mouse embryonic epiblast
    • Yan J., et al. COP9 signalosome subunit 3 (Csn3) is essential for maintenance of cell proliferation in the mouse embryonic epiblast. Mol. Cell. Biol. 23 (2003) 6798-6808
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 6798-6808
    • Yan, J.1
  • 83
    • 17344364820 scopus 로고    scopus 로고
    • CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability
    • Wee S., et al. CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability. Nat. Cell Biol. 7 (2005) 387-391
    • (2005) Nat. Cell Biol. , vol.7 , pp. 387-391
    • Wee, S.1
  • 84
    • 1542314268 scopus 로고    scopus 로고
    • Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor β signaling by binding to Smad7 and promoting its degradation
    • Kim B.-C., et al. Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor β signaling by binding to Smad7 and promoting its degradation. Mol. Cell. Biol. 24 (2004) 2251-2262
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 2251-2262
    • Kim, B.-C.1
  • 85
    • 3843060266 scopus 로고    scopus 로고
    • Interaction between glucose-regulated destruction domain of DNA topoisomerase IIα and MPN domain of Jab1/CSN5
    • Yun J., et al. Interaction between glucose-regulated destruction domain of DNA topoisomerase IIα and MPN domain of Jab1/CSN5. J. Biol. Chem. 279 (2004) 31296-31303
    • (2004) J. Biol. Chem. , vol.279 , pp. 31296-31303
    • Yun, J.1
  • 86
    • 35548932509 scopus 로고    scopus 로고
    • GLH-1, the C. elegans P granule protein, is controlled by the JNK KGB-1 and by the COP9 subunit CSN-5
    • Orsborn A.M., et al. GLH-1, the C. elegans P granule protein, is controlled by the JNK KGB-1 and by the COP9 subunit CSN-5. Development 134 (2007) 3383-3392
    • (2007) Development , vol.134 , pp. 3383-3392
    • Orsborn, A.M.1
  • 87
    • 27144525246 scopus 로고    scopus 로고
    • Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation
    • Wu J.T., et al. Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation. Nat. Cell Biol. 7 (2005) 1014-1020
    • (2005) Nat. Cell Biol. , vol.7 , pp. 1014-1020
    • Wu, J.T.1
  • 88
    • 21844464322 scopus 로고    scopus 로고
    • The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1
    • Hetfeld B.K., et al. The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1. Curr. Biol. 15 (2005) 1217-1221
    • (2005) Curr. Biol. , vol.15 , pp. 1217-1221
    • Hetfeld, B.K.1
  • 89
    • 33947606938 scopus 로고    scopus 로고
    • CSN controls NF-κB by deubiquitinylation of IκBα
    • Schweitzer K., et al. CSN controls NF-κB by deubiquitinylation of IκBα. EMBO J. 26 (2007) 1532-1541
    • (2007) EMBO J. , vol.26 , pp. 1532-1541
    • Schweitzer, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.