Scaffold proteins: Hubs for controlling the flow of cellular information

Science

Volumn 332, Issue 6030, 2011, Pages 680-686

  Good, Matthew C ^a,c   Zalatan, Jesse G ^a   Lim, Wendell A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of California Berkeley   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SCAFFOLD PROTEIN;

FLOW CYTOMETRY; PROTEIN; SPATIOTEMPORAL ANALYSIS;

BIOENGINEERING; CELL COMMUNICATION; CELL FUNCTION; CELL SHAPE; HUMAN IMMUNODEFICIENCY VIRUS; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FUNCTION; REVIEW; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; YERSINIA PESTIS;

ALLOSTERIC REGULATION; ANIMALS; EVOLUTION, MOLECULAR; FEEDBACK, PHYSIOLOGICAL; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; METABOLIC NETWORKS AND PATHWAYS; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEINS; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 79955770162     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1198701     Document Type: Review

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58. We thank P. Pryciak, A. Weiss, R. Nicoll, R. Phillips, N. Pierce, J. Iwasa, J. Dueber, A. Remenyi, M. Borovinskaya, S. Peisajovich, J. Garbarino, A. Won, C. Bashor, N. Helman, S. H. Park, S. Coyle, P. Wei, J. Toettcher, and othermembers of the Lim lab for helpful discussions and comments. Supported by a Miller Fellowship (M.C.G.), a Damon Runyon Fellowship (J.G.Z.), NIH grants RO1GM055040, RO1GM062583, PN2EY016546, and P50GM081879 (W.A.L.), the NSF Synthetic Biology and Engineering Research Center (W.A.L.), the Packard Foundation (W.A.L.), and the Howard Hughes Medical Institute (W.A.L.).