-
1
-
-
33947445379
-
A Theory of the Structure and Process of Formation of Antibodies*
-
10.1021/ja01867a018
-
L. Pauling A Theory of the Structure and Process of Formation of Antibodies* J. Am. Chem. Soc. 1940 62 2643 2657 10.1021/ja01867a018
-
(1940)
J. Am. Chem. Soc.
, vol.62
, pp. 2643-2657
-
-
Pauling, L.1
-
2
-
-
0030691703
-
-
Identifying disordered regions in proteins from amino acid sequence, in Neural Networks, 1997, International Conference on. 1. 90-95 1. DOI: 10.1109/ICNN.1997.611643
-
P. Romero, Z. Obradovic, C. Kissinger, J. E. Villafranca, A. K. Dunker, Identifying disordered regions in proteins from amino acid sequence, in Neural Networks, 1997, International Conference on. vol. 1. pp. 90-95 vol. 1. DOI: 10.1109/ICNN.1997.611643
-
-
-
Romero, P.1
Obradovic, Z.2
Kissinger, C.3
Villafranca, J.E.4
Dunker, A.K.5
-
3
-
-
49249151121
-
Conformational flexibility and its functional significance in some protein molecules
-
10.1016/0968-0004(79)90298-6
-
R. Huber Conformational flexibility and its functional significance in some protein molecules Trends Biochem. Sci. 1979 4 276 277 10.1016/0968-0004(79) 90298-6
-
(1979)
Trends Biochem. Sci.
, vol.4
, pp. 276-277
-
-
Huber, R.1
-
4
-
-
52249085709
-
The unfoldomics decade: An update on intrinsically disordered proteins
-
A. K. Dunker C. Oldfield J. Meng P. Romero J. Yang et al. The unfoldomics decade: an update on intrinsically disordered proteins BMC Genomics 2008 9 272 276
-
(2008)
BMC Genomics
, vol.9
, pp. 272-276
-
-
Dunker, A.K.1
Oldfield, C.2
Meng, J.3
Romero, P.4
Yang, J.5
-
5
-
-
14644435825
-
Intrinsically unstructured proteins and their functions
-
DOI 10.1038/nrm1589
-
H. J. Dyson P. E. Wright Intrinsically unstructured proteins and their functions Nat. Rev. Mol. Cell Biol. 2005 6 197 208 10.1038/nrm1589 (Pubitemid 40314921)
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, Issue.3
, pp. 197-208
-
-
Dyson, H.J.1
Wright, P.E.2
-
6
-
-
0242458482
-
Protein disorder prediction: Implications for structural proteomics
-
DOI 10.1016/j.str.2003.10.002
-
R. Linding L. J. Jensen F. Diella P. Bork T. J. Gibson et al. Protein disorder prediction: implications for structural proteomics Structure 2003 11 1453 1459 (Pubitemid 37412427)
-
(2003)
Structure
, vol.11
, Issue.11
, pp. 1453-1459
-
-
Linding, R.1
Jensen, L.J.2
Diella, F.3
Bork, P.4
Gibson, T.J.5
Russell, R.B.6
-
7
-
-
0042622240
-
GlobPlot: Exploring protein sequences for globularity and disorder
-
DOI 10.1093/nar/gkg519
-
R. Linding R. B. Russell V. Neduva T. J. Gibson GlobPlot: Exploring protein sequences for globularity and disorder Nucleic Acids Res. 2003 31 3701 3708 (Pubitemid 37442227)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.13
, pp. 3701-3708
-
-
Linding, R.1
Russell, R.B.2
Neduva, V.3
Gibson, T.J.4
-
8
-
-
24044515001
-
FoldIndex©: A simple tool to predict whether a given protein sequence is intrinsically unfolded
-
DOI 10.1093/bioinformatics/bti537
-
J. Prilusky C. E. Felder T. Zeev-Ben-Mordehai E. H. Rydberg O. Man et al. FoldIndex: a simple tool to predict whether a given protein sequence is intrinsically unfolded Bioinformatics 2005 21 3435 3438 10.1093/bioinformatics/ bti537 (Pubitemid 41222454)
-
(2005)
Bioinformatics
, vol.21
, Issue.16
, pp. 3435-3438
-
-
Prilusky, J.1
Felder, C.E.2
Zeev-Ben-Mordehai, T.3
Rydberg, E.H.4
Man, O.5
Beckmann, J.S.6
Silman, I.7
Sussman, J.L.8
-
9
-
-
0041620131
-
NORSp: Predictions of long regions without regular secondary structure
-
DOI 10.1093/nar/gkg515
-
J. Liu B. Rost NORSp: Predictions of long regions without regular secondary structure Nucleic Acids Res. 2003 31 3833 3835 (Pubitemid 37442259)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.13
, pp. 3833-3835
-
-
Liu, J.1
Rost, B.2
-
11
-
-
1542358787
-
Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life
-
DOI 10.1016/j.jmb.2004.02.002, PII S0022283604001482
-
J. J. Ward J. S. Sodhi L. J. McGuffin B. F. Buxton D. T. Jones Prediction and functional analysis of native disorder in proteins from the three kingdoms of life J. Mol. Biol. 2004 337 635 645 10.1016/j.jmb.2004.02.002 (Pubitemid 38326883)
-
(2004)
Journal of Molecular Biology
, vol.337
, Issue.3
, pp. 635-645
-
-
Ward, J.J.1
Sodhi, J.S.2
McGuffin, L.J.3
Buxton, B.F.4
Jones, D.T.5
-
12
-
-
24044538903
-
IUPred: Web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content
-
DOI 10.1093/bioinformatics/bti541
-
Z. Dosztányi V. Csizmok P. Tompa I. Simon IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content Bioinformatics 2005 21 3433 3434 10.1093/ bioinformatics/bti541 (Pubitemid 41222453)
-
(2005)
Bioinformatics
, vol.21
, Issue.16
, pp. 3433-3434
-
-
Dosztanyi, Z.1
Csizmok, V.2
Tompa, P.3
Simon, I.4
-
13
-
-
24044515001
-
FoldIndex©: A simple tool to predict whether a given protein sequence is intrinsically unfolded
-
DOI 10.1093/bioinformatics/bti537
-
J. Prilusky C. E. Felder T. Zeev-Ben-Mordehai E. H. Rydberg O. Man et al. FoldIndex©: a simple tool to predict whether a given protein sequence is intrinsically unfolded Bioinformatics 2005 21 3435 3438 10.1093/bioinformatics/ bti537 (Pubitemid 41222454)
-
(2005)
Bioinformatics
, vol.21
, Issue.16
, pp. 3435-3438
-
-
Prilusky, J.1
Felder, C.E.2
Zeev-Ben-Mordehai, T.3
Rydberg, E.H.4
Man, O.5
Beckmann, J.S.6
Silman, I.7
Sussman, J.L.8
-
14
-
-
20744437001
-
RONN: The bio-basis function neural network technique applied to the detection of natively disordered regions in proteins
-
DOI 10.1093/bioinformatics/bti534
-
Z. R. Yang R. Thomson P. McNeil R. M. Esnouf RONN: the bio-basis function neural network technique applied to the detection of natively disordered regions in proteins Bioinformatics 2005 21 3369 3376 10.1093/bioinformatics/ bti534 (Pubitemid 41222441)
-
(2005)
Bioinformatics
, vol.21
, Issue.16
, pp. 3369-3376
-
-
Yang, Z.R.1
Thomson, R.2
McNeil, P.3
Esnouf, R.M.4
-
15
-
-
33747868721
-
Spritz: A server for the prediction of intrinsically disordered regions in protein sequences using kernel machines
-
DOI 10.1093/nar/gkl166
-
A. Vullo O. Bortolami G. Pollastri S. C. E. Tosatto Spritz: a server for the prediction of intrinsically disordered regions in protein sequences using kernel machines Nucleic Acids Res. 2006 34 W164 168 10.1093/nar/gkl166 (Pubitemid 44529756)
-
(2006)
Nucleic Acids Research
, vol.34
, Issue.WEB. SERV. ISS.
-
-
Vullo, A.1
Bortolamil, O.2
Pollastri, G.3
Tosatto, S.C.E.4
-
16
-
-
33746630984
-
Wiggle - Predicting functionally flexible regions from primary sequence
-
DOI 10.1371/journal.pcbi.0020090
-
J. Gu M. Gribskov P. E. Bourne Wiggle-predicting functionally flexible regions from primary sequence PLoS Comput. Biol. 2006 2 e90 10.1371/journal. pcbi.0020090 (Pubitemid 44147387)
-
(2006)
PLoS Computational Biology
, vol.2
, Issue.7
, pp. 0769-0785
-
-
Gu, J.1
Gribskov, M.2
Bourne, P.E.3
-
17
-
-
84885949386
-
Improved disorder prediction by combination of orthogonal approaches
-
10.1371/journal.pone.0004433
-
A. Schlessinger M. Punta G. Yachdav L. Kajan B. Rost Improved disorder prediction by combination of orthogonal approaches PLoS One 2009 4 e4433 10.1371/journal.pone.0004433
-
(2009)
PLoS One
, vol.4
, pp. 4433
-
-
Schlessinger, A.1
Punta, M.2
Yachdav, G.3
Kajan, L.4
Rost, B.5
-
18
-
-
0035188314
-
Sequence complexity of disordered protein
-
P. Romero Z. Obradovic X. Li E. C. Garner C. J. Brown et al. Sequence complexity of disordered protein Proteins: Struct., Funct., Genet. 2001 42 38 48
-
(2001)
Proteins: Struct., Funct., Genet.
, vol.42
, pp. 38-48
-
-
Romero, P.1
Obradovic, Z.2
Li, X.3
Garner, E.C.4
Brown, C.J.5
-
19
-
-
34748854289
-
Predicting mostly disordered proteins by using structure-unknown protein data
-
10.1186/1471-2105-8-78
-
K. Shimizu Y. Muraoka S. Hirose K. Tomii T. Noguchi Predicting mostly disordered proteins by using structure-unknown protein data BMC Bioinformatics 2007 8 78 10.1186/1471-2105-8-78
-
(2007)
BMC Bioinformatics
, vol.8
, pp. 78
-
-
Shimizu, K.1
Muraoka, Y.2
Hirose, S.3
Tomii, K.4
Noguchi, T.5
-
20
-
-
44349192171
-
Prediction of disordered regions in proteins based on the meta approach
-
DOI 10.1093/bioinformatics/btn195
-
T. Ishida K. Kinoshita Prediction of disordered regions in proteins based on the meta approach Bioinformatics 2008 24 1344 1348 10.1093/bioinformatics/ btn195 (Pubitemid 351737139)
-
(2008)
Bioinformatics
, vol.24
, Issue.11
, pp. 1344-1348
-
-
Ishida, T.1
Kinoshita, K.2
-
22
-
-
77955792980
-
Consistent refinement of submitted models at CASP using a knowledge-based potential
-
10.1002/prot.22781
-
G. Chopra N. Kalisman M. Levitt Consistent refinement of submitted models at CASP using a knowledge-based potential Proteins: Struct., Funct., Bioinf. 2010 78 2668 2678 10.1002/prot.22781
-
(2010)
Proteins: Struct., Funct., Bioinf.
, vol.78
, pp. 2668-2678
-
-
Chopra, G.1
Kalisman, N.2
Levitt, M.3
-
23
-
-
71749098088
-
ELM: The status of the 2010 eukaryotic linear motif resource
-
10.1093/nar/gkp1016 Protein Data Bank (n.d.) []
-
C. M. Gould F. Diella A. Via P. Puntervoll C. Gemund et al. ELM: the status of the 2010 eukaryotic linear motif resource Nucleic Acids Res. 2009 38 D167 D180 10.1093/nar/gkp1016
-
(2009)
Nucleic Acids Res.
, vol.38
-
-
Gould, C.M.1
Diella, F.2
Via, A.3
Puntervoll, P.4
Gemund, C.5
-
24
-
-
41149120313
-
SLiMFinder: A probabilistic method for identifying over-represented, convergently evolved, short linear motifs in proteins
-
DOI 10.1371/journal.pone.0000967
-
R. J. Edwards N. E. Davey D. C. Shields SLiMFinder: A Probabilistic Method for Identifying Over-Represented, Convergently Evolved, Short Linear Motifs in Proteins PLoS One 2007 2 e967 10.1371/journal.pone.0000967 (Pubitemid 351460822)
-
(2007)
PLoS ONE
, vol.2
, Issue.10
-
-
Edwards, R.J.1
Davey, N.E.2
Shields, D.C.3
-
25
-
-
0042622251
-
Scansite 2.0: Proteome-wide prediction of cell signalling interactions using short sequence motifs
-
DOI 10.1093/nar/gkg584
-
J. C. Obenauer L. C. Cantley M. B. Yaffe Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs Nucleic Acids Res. 2003 31 3635 3641 (Pubitemid 37442212)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.13
, pp. 3635-3641
-
-
Obenauer, J.C.1
Cantley, L.C.2
Yaffe, M.B.3
-
26
-
-
33847768609
-
Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions
-
DOI 10.1021/pr060392u
-
H. Xie S. Vucetic L. M. Iakoucheva C. J. Oldfield A. K. Dunker et al. Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions J. Proteome Res. 2007 6 1882 1898 10.1021/pr060392u (Pubitemid 46814512)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.5
, pp. 1882-1898
-
-
Xie, H.1
Vucetic, S.2
Iakoucheva, L.M.3
Oldfield, C.J.4
Dunker, A.K.5
Uversky, V.N.6
Obradovic, Z.7
-
27
-
-
34249282661
-
Functional anthology of intrinsic disorder. 2. cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions
-
DOI 10.1021/pr060393m
-
S. Vucetic H. Xie L. M. Iakoucheva C. J. Oldfield A. K. Dunker et al. Functional Anthology of Intrinsic Disorder. 2. Cellular Components, Domains, Technical Terms, Developmental Processes, and Coding Sequence Diversities Correlated with Long Disordered Regions J. Proteome Res. 2007 6 1899 1916 10.1021/pr060393m (Pubitemid 46814513)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.5
, pp. 1899-1916
-
-
Vucetic, S.1
Xie, H.2
Iakoucheva, L.M.3
Oldfield, C.J.4
Dunker, A.K.5
Obradovic, Z.6
Uversky, V.N.7
-
28
-
-
33847783298
-
Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins
-
DOI 10.1021/pr060394e
-
H. Xie S. Vucetic L. M. Iakoucheva C. J. Oldfield A. K. Dunker et al. Functional Anthology of Intrinsic Disorder. 3. Ligands, Post-Translational Modifications, and Diseases Associated with Intrinsically Disordered Proteins J. Proteome Res. 2007 6 1917 1932 10.1021/pr060394e (Pubitemid 46814514)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.5
, pp. 1917-1932
-
-
Xie, H.1
Vucetic, S.2
Iakoucheva, L.M.3
Oldfield, C.J.4
Dunker, A.K.5
Obradovic, Z.6
Uversky, V.N.7
-
29
-
-
33747191719
-
Prevalent structural disorder in E. coli and S. cerevisiae proteomes
-
DOI 10.1021/pr0600881
-
P. Tompa Z. Dosztanyi I. Simon Prevalent structural disorder in E. coli and S. cerevisiae proteomes J. Proteome Res. 2006 5 1996 2000 10.1021/pr0600881 (Pubitemid 44232712)
-
(2006)
Journal of Proteome Research
, vol.5
, Issue.8
, pp. 1996-2000
-
-
Tompa, P.1
Dosztanyi, Z.2
Simon, I.3
-
31
-
-
34548448958
-
Inferring function using patterns of native disorder in proteins
-
DOI 10.1371/journal.pcbi.0030162
-
A. Lobley M. B. Swindells C. A. Orengo D. T. Jones Inferring Function Using Patterns of Native Disorder in Proteins PLoS Comput. Biol. 2007 3 e162 10.1371/journal.pcbi.0030162 (Pubitemid 47358064)
-
(2007)
PLoS Computational Biology
, vol.3
, Issue.8
, pp. 1567-1579
-
-
Lobley, A.1
Swindells, M.B.2
Orengo, C.A.3
Jones, D.T.4
-
32
-
-
2342473198
-
The importance of intrinsic disorder for protein phosphorylation
-
DOI 10.1093/nar/gkh253
-
L. M. Iakoucheva P. Radivojac C. J. Brown T. R. O'Connor J. G. Sikes et al. The importance of intrinsic disorder for protein phosphorylation Nucleic Acids Res. 2004 32 1037 1049 10.1093/nar/gkh253 (Pubitemid 38854704)
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.3
, pp. 1037-1049
-
-
Iakoucheva, L.M.1
Radivojac, P.2
Brown, C.J.3
O'Connor, T.R.4
Sikes, J.G.5
Obradovic, Z.6
Dunker, A.K.7
-
33
-
-
77949360998
-
Modularity of intrinsic disorder in the human proteome
-
10.1002/prot.22504
-
M. M. Pentony D. T. Jones Modularity of intrinsic disorder in the human proteome Proteins: Struct., Funct., Bioinf. 2010 78 212 221 10.1002/prot.22504
-
(2010)
Proteins: Struct., Funct., Bioinf.
, vol.78
, pp. 212-221
-
-
Pentony, M.M.1
Jones, D.T.2
-
34
-
-
77955551442
-
Harge-rich regions modulate the anti-aggregation activity of Hsp90
-
10.1016/j.jmb.2010.06.066
-
N. Wayne D. N. Bolon harge-rich regions modulate the anti-aggregation activity of Hsp90 J. Mol. Biol. 2010 401 931 939 10.1016/j.jmb.2010.06.066
-
(2010)
J. Mol. Biol.
, vol.401
, pp. 931-939
-
-
Wayne, N.1
Bolon, D.N.2
-
35
-
-
77952882922
-
Comparative Genomics and Disorder Prediction Identify Biologically Relevant SH3 Protein Interactions
-
10.1371/journal.pcbi.0010026
-
P. Beltrao L. Serrano Comparative Genomics and Disorder Prediction Identify Biologically Relevant SH3 Protein Interactions PLoS Comput. Biol. 2005 1 e26 10.1371/journal.pcbi.0010026
-
(2005)
PLoS Comput. Biol.
, vol.1
, pp. 26
-
-
Beltrao, P.1
Serrano, L.2
-
36
-
-
77954694216
-
Investigating the disorder-order transition of calmodulin binding domain upon binding calmodulin using molecular dynamics simulation
-
10.1002/jmr.1002
-
Y. Zhang H. Tan G. Chen Z. Jia Investigating the disorder-order transition of calmodulin binding domain upon binding calmodulin using molecular dynamics simulation J. Mol. Recognit. 2009 23 360 368 10.1002/jmr.1002
-
(2009)
J. Mol. Recognit.
, vol.23
, pp. 360-368
-
-
Zhang, Y.1
Tan, H.2
Chen, G.3
Jia, Z.4
-
37
-
-
77954615134
-
A bimodal distribution of two distinct categories of intrinsically- disordered structures with separate functions in FG nucleoporins
-
Available:. Accessed 3 Jun 2011
-
J. Yamada J. L. Phillips S. Patel G. Goldfien A. Calestagne-Morelli et al. A bimodal distribution of two distinct categories of intrinsically- disordered structures with separate functions in FG nucleoporins Mol. Cell. Proteomics 2010
-
(2010)
Mol. Cell. Proteomics
-
-
Yamada, J.1
Phillips, J.L.2
Patel, S.3
Goldfien, G.4
Calestagne-Morelli, A.5
-
38
-
-
67650369989
-
Unfoldomics of human diseases: Linking protein intrinsic disorder with diseases
-
10.1186/1471-2164-10-S1-S7
-
V. Uversky C. Oldfield U. Midic H. Xie B. Xue et al. Unfoldomics of human diseases: linking protein intrinsic disorder with diseases BMC Genomics 2009 10 S7 10.1186/1471-2164-10-S1-S7
-
(2009)
BMC Genomics
, vol.10
, pp. 7
-
-
Uversky, V.1
Oldfield, C.2
Midic, U.3
Xie, H.4
Xue, B.5
-
39
-
-
9644252804
-
Characterization of segments from the central region of BRCA1: An intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions?
-
DOI 10.1016/j.jmb.2004.10.045, PII S0022283604013373
-
W.-Y. Mark J. C. C. Liao Y. Lu A. Ayed R. Laister et al. Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions? J. Mol. Biol. 2005 345 275 287 10.1016/j.jmb.2004.10.045 (Pubitemid 39574850)
-
(2005)
Journal of Molecular Biology
, vol.345
, Issue.2
, pp. 275-287
-
-
Mark, W.-Y.1
Liao, J.C.C.2
Lu, Y.3
Ayed, A.4
Laister, R.5
Szymczyna, B.6
Chakrabartty, A.7
Arrowsmith, C.H.8
-
40
-
-
67650904949
-
Integrated Assessment of Genomic Correlates of Protein Evolutionary Rate
-
10.1371/journal.pcbi.1000413
-
Y. Xia E. A. Franzosa M. B. Gerstein Integrated Assessment of Genomic Correlates of Protein Evolutionary Rate PLoS Comput. Biol. 2009 5 e1000413 10.1371/journal.pcbi.1000413
-
(2009)
PLoS Comput. Biol.
, vol.5
, pp. 1000413
-
-
Xia, Y.1
Franzosa, E.A.2
Gerstein, M.B.3
-
41
-
-
41149119083
-
The role of disorder in interaction networks: A structural analysis
-
Available:. Accessed 3 Mar 2010
-
P. M. Kim A. Sboner Y. Xia M. Gerstein The role of disorder in interaction networks: a structural analysis Mol. Syst. Biol. 2008 4
-
(2008)
Mol. Syst. Biol.
, pp. 4
-
-
Kim, P.M.1
Sboner, A.2
Xia, Y.3
Gerstein, M.4
-
42
-
-
79851508882
-
Bringing order to protein disorder through comparative genomics and genetic interactions
-
J. Bellay S. Han M. Michaut T. Kim M. Costanzo et al. Bringing order to protein disorder through comparative genomics and genetic interactions GenomeBiology 2011 12 R14
-
(2011)
GenomeBiology
, vol.12
, pp. 14
-
-
Bellay, J.1
Han, S.2
Michaut, M.3
Kim, T.4
Costanzo, M.5
-
43
-
-
33645778262
-
Conservation of Intrinsic Disorder in Protein Domains and Families: I. A Database of Conserved Predicted Disordered Regions
-
10.1021/pr060048x
-
J. W. Chen P. Romero V. N. Uversky A. K. Dunker Conservation of Intrinsic Disorder in Protein Domains and Families: I. A Database of Conserved Predicted Disordered Regions J. Proteome Res. 2006 5 879 887 10.1021/pr060048x
-
(2006)
J. Proteome Res.
, vol.5
, pp. 879-887
-
-
Chen, J.W.1
Romero, P.2
Uversky, V.N.3
Dunker, A.K.4
-
44
-
-
33645753974
-
Conservation of Intrinsic Disorder in Protein Domains and Families: II. Functions of Conserved Disorder
-
10.1021/pr060049p
-
J. W. Chen P. Romero V. N. Uversky A. K. Dunker Conservation of Intrinsic Disorder in Protein Domains and Families: II. Functions of Conserved Disorder J. Proteome Res. 2006 5 888 898 10.1021/pr060049p
-
(2006)
J. Proteome Res.
, vol.5
, pp. 888-898
-
-
Chen, J.W.1
Romero, P.2
Uversky, V.N.3
Dunker, A.K.4
-
45
-
-
77949629173
-
Protein secondary structure appears to be robust under in silico evolution while protein disorder appears not to be
-
10.1093/bioinformatics/btq012
-
C. Schaefer A. Schlessinger B. Rost Protein secondary structure appears to be robust under in silico evolution while protein disorder appears not to be Bioinformatics 2010 26 625 631 10.1093/bioinformatics/btq012
-
(2010)
Bioinformatics
, vol.26
, pp. 625-631
-
-
Schaefer, C.1
Schlessinger, A.2
Rost, B.3
-
46
-
-
57149116929
-
Tight regulation of unstructured proteins: From transcript synthesis to protein degradation
-
DOI 10.1126/science.1163581
-
J. Gsponer M. E. Futschik S. A. Teichmann M. M. Babu Tight Regulation of Unstructured Proteins: From Transcript Synthesis to Protein Degradation Science 2008 322 1365 1368 10.1126/science.1163581 (Pubitemid 352775246)
-
(2008)
Science
, vol.322
, Issue.5906
, pp. 1365-1368
-
-
Gsponer, J.1
Futschik, M.E.2
Teichmann, S.A.3
Babu, M.M.4
-
47
-
-
5044235541
-
Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins
-
DOI 10.1038/nbt1012
-
A.-M. Fernandez-Escamilla F. Rousseau J. Schymkowitz L. Serrano Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins Nat. Biotechnol. 2004 22 1302 1306 10.1038/nbt1012 (Pubitemid 39336784)
-
(2004)
Nature Biotechnology
, vol.22
, Issue.10
, pp. 1302-1306
-
-
Fernandez-Escamilla, A.-M.1
Rousseau, F.2
Schymkowitz, J.3
Serrano, L.4
-
48
-
-
67649635978
-
Intrinsic protein disorder and interaction promiscuity are widely associated with dosage sensitivity
-
10.1016/j.cell.2009.04.029
-
T. Vavouri J. I. Semple R. Garcia-Verdugo B. Lehner Intrinsic protein disorder and interaction promiscuity are widely associated with dosage sensitivity Cell 2009 138 198 208 10.1016/j.cell.2009.04.029
-
(2009)
Cell
, vol.138
, pp. 198-208
-
-
Vavouri, T.1
Semple, J.I.2
Garcia-Verdugo, R.3
Lehner, B.4
-
49
-
-
79954610505
-
A multi-protein binding interface in an intrinsically disordered region of the tumour suppressor protein interferon regulatory factor-1
-
Available:. Accessed 24 May 2011
-
V. Narayan P. Halada L. Hernychova Y. P. Chong J. Zakova et al. A multi-protein binding interface in an intrinsically disordered region of the tumour suppressor protein interferon regulatory factor-1 J. Biol. Chem. 2011
-
(2011)
J. Biol. Chem.
-
-
Narayan, V.1
Halada, P.2
Hernychova, L.3
Chong, Y.P.4
Zakova, J.5
-
50
-
-
47849089500
-
Phosphoproteomic analysis of the mouse brain cytosol reveals a predominance of protein phosphorylation in regions of intrinsic sequence diorder
-
DOI 10.1074/mcp.M700564-MCP200
-
M. O. Collins L. Yu I. Campuzano S. G. N. Grant J. S. Choudhary Phosphoproteomic Analysis of the Mouse Brain Cytosol Reveals a Predominance of Protein Phosphorylation in Regions of Intrinsic Sequence Disorder Mol. Cell. Proteomics 2008 7 1331 1348 10.1074/mcp.M700564-MCP200 (Pubitemid 352038276)
-
(2008)
Molecular and Cellular Proteomics
, vol.7
, Issue.7
, pp. 1331-1348
-
-
Collins, M.O.1
Yu, L.2
Campuzano, I.3
Grant, S.G.N.4
Choudhary, J.S.5
-
51
-
-
67649654466
-
Disorder, promiscuity, and toxic partnerships
-
10.1016/j.cell.2009.06.024
-
E. M. Marcotte M. Tsechansky Disorder, promiscuity, and toxic partnerships Cell 2009 138 16 18 10.1016/j.cell.2009.06.024
-
(2009)
Cell
, vol.138
, pp. 16-18
-
-
Marcotte, E.M.1
Tsechansky, M.2
-
52
-
-
41149125082
-
Structural disorder serves as a weak signal for intracellular protein degradation
-
DOI 10.1002/prot.21773
-
P. Tompa J. Prilusky I. Silman J. L. Sussman Structural disorder serves as a weak signal for intracellular protein degradation Proteins: Struct., Funct., Bioinf. 2008 71 903 909 10.1002/prot.21773 (Pubitemid 351430024)
-
(2008)
Proteins: Structure, Function and Genetics
, vol.71
, Issue.2
, pp. 903-909
-
-
Tompa, P.1
Prilusky, J.2
Silman, I.3
Sussman, J.L.4
-
54
-
-
70350308428
-
Susceptibility of p53 Unstructured N Terminus to 20 S Proteasomal Degradation Programs the Stress Response
-
10.1074/jbc.M109.040493
-
P. Tsvetkov N. Reuven C. Prives Y. Shaul Susceptibility of p53 Unstructured N Terminus to 20 S Proteasomal Degradation Programs the Stress Response J. Biol. Chem. 2009 284 26234 26242 10.1074/jbc.M109.040493
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 26234-26242
-
-
Tsvetkov, P.1
Reuven, N.2
Prives, C.3
Shaul, Y.4
-
55
-
-
37749053887
-
Fuzzy complexes: Polymorphism and structural disorder in protein-protein interactions
-
10.1016/j.tibs.2007.10.003
-
P. Tompa M. Fuxreiter Fuzzy complexes: polymorphism and structural disorder in protein-protein interactions Trends Biochem. Sci. 2008 33 2 8 10.1016/j.tibs.2007.10.003
-
(2008)
Trends Biochem. Sci.
, vol.33
, pp. 2-8
-
-
Tompa, P.1
Fuxreiter, M.2
-
56
-
-
20444376186
-
The interplay between structure and function in intrinsically unstructured proteins
-
DOI 10.1016/j.febslet.2005.03.072, PII S0014579305004242
-
P. Tompa The interplay between structure and function in intrinsically unstructured proteins FEBS Lett. 2005 579 3346 3354 10.1016/j.febslet.2005.03. 072 (Pubitemid 40804685)
-
(2005)
FEBS Letters
, vol.579
, Issue.15
, pp. 3346-3354
-
-
Tompa, P.1
-
57
-
-
0041418213
-
Flavors of protein disorder
-
DOI 10.1002/prot.10437
-
S. Vucetic C. J. Brown A. K. Dunker Z. Obradovic Flavors of protein disorder Proteins: Struct., Funct., Genet. 2003 52 573 584 10.1002/prot.10437 (Pubitemid 37034155)
-
(2003)
Proteins: Structure, Function and Genetics
, vol.52
, Issue.4
, pp. 573-584
-
-
Vucetic, S.1
Brown, C.J.2
Dunker, A.K.3
Obradovic, Z.4
-
58
-
-
33947725810
-
Is the intrinsic disorder of proteins the cause of the scale-free architecture of protein-protein interaction networks?
-
DOI 10.1002/pmic.200600455
-
S. Schnell S. Fortunato S. Roy Is the intrinsic disorder of proteins the cause of the scale-free architecture of protein-protein interaction networks? Proteomics 2007 7 961 964 10.1002/pmic.200600455 (Pubitemid 46506742)
-
(2007)
Proteomics
, vol.7
, Issue.6
, pp. 961-964
-
-
Schnell, S.1
Fortunato, S.2
Roy, S.3
-
59
-
-
33644555054
-
Proteome survey reveals modularity of the yeast cell machinery
-
10.1038/nature04532
-
A.-C. Gavin P. Aloy P. Grandi R. Krause M. Boesche et al. Proteome survey reveals modularity of the yeast cell machinery Nature 2006 440 631 636 10.1038/nature04532
-
(2006)
Nature
, vol.440
, pp. 631-636
-
-
Gavin, A.-C.1
Aloy, P.2
Grandi, P.3
Krause, R.4
Boesche, M.5
-
60
-
-
33645453254
-
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae
-
10.1038/nature04670
-
N. J. Krogan G. Cagney H. Yu G. Zhong X. Guo et al. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae Nature 2006 440 637 643 10.1038/nature04670
-
(2006)
Nature
, vol.440
, pp. 637-643
-
-
Krogan, N.J.1
Cagney, G.2
Yu, H.3
Zhong, G.4
Guo, X.5
-
61
-
-
53349117774
-
High-Quality Binary Protein Interaction Map of the Yeast Interactome Network
-
10.1126/science.1158684
-
H. Yu P. Braun M. A. Yildirim I. Lemmens K. Venkatesan et al. High-Quality Binary Protein Interaction Map of the Yeast Interactome Network Science 2008 322 104 110 10.1126/science.1158684
-
(2008)
Science
, vol.322
, pp. 104-110
-
-
Yu, H.1
Braun, P.2
Yildirim, M.A.3
Lemmens, I.4
Venkatesan, K.5
-
62
-
-
77953077420
-
Global Protein Kinase and Phosphatase Interaction Network in Yeast
-
10.1126/science.1176495
-
A. Breitkreutz H. Choi J. R. Sharom L. Boucher V. Neduva et al. Global Protein Kinase and Phosphatase Interaction Network in Yeast Science 2010 328 1043 1046 10.1126/science.1176495
-
(2010)
Science
, vol.328
, pp. 1043-1046
-
-
Breitkreutz, A.1
Choi, H.2
Sharom, J.R.3
Boucher, L.4
Neduva, V.5
-
63
-
-
45849110261
-
An in vivo map of the yeast protein interactome
-
DOI 10.1126/science.1153878
-
K. Tarassov V. Messier C. R. Landry S. Radinovic M. M. S. Molina et al. An in vivo Map of the Yeast Protein Interactome Science 2008 320 1465 1470 10.1126/science.1153878 (Pubitemid 351929421)
-
(2008)
Science
, vol.320
, Issue.5882
, pp. 1465-1470
-
-
Tarassov, K.1
Messier, V.2
Landry, C.R.3
Radinovic, S.4
Serna Molina, M.M.5
Shames, I.6
Malitskaya, Y.7
Vogel, J.8
Bussey, H.9
Michnick, S.W.10
-
64
-
-
63549102895
-
Intrinsic disorder in protein interactions: Insights from a comprehensive structural analysis
-
10.1371/journal.pcbi.1000316
-
J. H. Fong B. A. Shoemaker S. O. Garbuzynskiy M. Y. Lobanov O. V. Galzitskaya et al. Intrinsic disorder in protein interactions: insights from a comprehensive structural analysis PLoS Comput. Biol. 2009 5 e1000316 10.1371/journal.pcbi.1000316
-
(2009)
PLoS Comput. Biol.
, vol.5
, pp. 1000316
-
-
Fong, J.H.1
Shoemaker, B.A.2
Garbuzynskiy, S.O.3
Lobanov, M.Y.4
Galzitskaya, O.V.5
-
65
-
-
60349101875
-
Linking folding and binding
-
10.1016/j.sbi.2008.12.003
-
P. E. Wright H. J. Dyson Linking folding and binding Curr. Opin. Struct. Biol. 2009 19 31 38 10.1016/j.sbi.2008.12.003
-
(2009)
Curr. Opin. Struct. Biol.
, vol.19
, pp. 31-38
-
-
Wright, P.E.1
Dyson, H.J.2
-
66
-
-
0037675852
-
Mutual induced fit binding of Xenopus ribosomal protein L5 to 5 S rRNA
-
DOI 10.1016/S0022-2836(03)00685-5
-
J. P. DiNitto P. W. Huber Mutual induced fit binding of Xenopus ribosomal protein L5 to 5S rRNA J. Mol. Biol. 2003 330 979 992 (Pubitemid 36818896)
-
(2003)
Journal of Molecular Biology
, vol.330
, Issue.5
, pp. 979-992
-
-
DiNitto, J.P.1
Huber, P.W.2
-
67
-
-
0023923585
-
Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein
-
10.1038/333635a0
-
I. A. Hope S. Mahadevan K. Struhl Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein Nature 1988 333 635 640 10.1038/333635a0
-
(1988)
Nature
, vol.333
, pp. 635-640
-
-
Hope, I.A.1
Mahadevan, S.2
Struhl, K.3
-
69
-
-
55749111058
-
Linear Motif Atlas for Phosphorylation-Dependent Signaling
-
10.1126/scisignal.1159433
-
M. L. Miller L. J. Jensen F. Diella C. Jorgensen M. Tinti et al. Linear Motif Atlas for Phosphorylation-Dependent Signaling Sci. Signaling 2008 1 ra2 10.1126/scisignal.1159433
-
(2008)
Sci. Signaling
, vol.1
, pp. 2
-
-
Miller, M.L.1
Jensen, L.J.2
Diella, F.3
Jorgensen, C.4
Tinti, M.5
-
70
-
-
0025294506
-
Peptide sequences that target cytosolic proteins for lysosomal proteolysis
-
J. F. Dice Peptide sequences that target cytosolic proteins for lysosomal proteolysis Trends Biochem. Sci. 1990 15 305 309 (Pubitemid 20223216)
-
(1990)
Trends in Biochemical Sciences
, vol.15
, Issue.8
, pp. 305-309
-
-
Dice, J.F.1
-
71
-
-
0027408247
-
Identification of a ten-amino acid proline-rich SH3 binding site
-
R. Ren B. Mayer P. Cicchetti D. Baltimore Identification of a ten-amino acid proline-rich SH3 binding site Science 1993 259 1157 1161 10.1126/science.8438166 (Pubitemid 23085353)
-
(1993)
Science
, vol.259
, Issue.5098
, pp. 1157-1161
-
-
Ren, R.1
Mayer, B.J.2
Cicchetti, P.3
Baltimore, D.4
-
72
-
-
70350404403
-
Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins
-
10.1371/journal.pbio.1000218
-
R. Tonikian X. Xin C. P. Toret D. Gfeller C. Landgraf et al. Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins PLoS Biol. 2009 7 e1000218 10.1371/journal.pbio.1000218
-
(2009)
PLoS Biol.
, vol.7
, pp. 1000218
-
-
Tonikian, R.1
Xin, X.2
Toret, C.P.3
Gfeller, D.4
Landgraf, C.5
-
73
-
-
49549122501
-
Understanding eukaryotic linear motifs and their role in cell signaling and regulation
-
F. Diella N. Haslam C. Chica A. Budd S. Michael et al. Understanding eukaryotic linear motifs and their role in cell signaling and regulation Front. Biosci. 2008 13 6580 6603
-
(2008)
Front. Biosci.
, vol.13
, pp. 6580-6603
-
-
Diella, F.1
Haslam, N.2
Chica, C.3
Budd, A.4
Michael, S.5
-
75
-
-
33748366578
-
Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1
-
DOI 10.1038/nsmb1133, PII NSMB1133
-
J. C. D. Houtman H. Yamaguchi M. Barda-Saad A. Braiman B. Bowden et al. Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1 Nat. Struct. Mol. Biol. 2006 13 798 805 10.1038/nsmb1133 (Pubitemid 44338774)
-
(2006)
Nature Structural and Molecular Biology
, vol.13
, Issue.9
, pp. 798-805
-
-
Houtman, J.C.D.1
Yamaguchi, H.2
Barda-Saad, M.3
Braiman, A.4
Bowden, B.5
Appella, E.6
Schuck, P.7
Samelson, L.E.8
-
76
-
-
34249695447
-
Local structural disorder imparts plasticity on linear motifs
-
DOI 10.1093/bioinformatics/btm035
-
M. Fuxreiter P. Tompa I. Simon Local structural disorder imparts plasticity on linear motifs Bioinformatics 2007 23 950 956 10.1093/ bioinformatics/btm035 (Pubitemid 47050581)
-
(2007)
Bioinformatics
, vol.23
, Issue.8
, pp. 950-956
-
-
Fuxreiter, M.1
Tompa, P.2
Simon, I.3
-
77
-
-
67649972198
-
Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species
-
10.1371/journal.pbio.1000134
-
P. Beltrao J. C. Trinidad D. Fiedler A. Roguev W. A. Lim et al. Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species PLoS Biol. 2009 7 e1000134 10.1371/journal.pbio.1000134
-
(2009)
PLoS Biol.
, vol.7
, pp. 1000134
-
-
Beltrao, P.1
Trinidad, J.C.2
Fiedler, D.3
Roguev, A.4
Lim, W.A.5
-
78
-
-
33847268619
-
Robustness Can Evolve Gradually in Complex Regulatory Gene Networks with Varying Topology
-
10.1371/journal.pcbi.0030015
-
S. Ciliberti O. C. Martin A. Wagner Robustness Can Evolve Gradually in Complex Regulatory Gene Networks with Varying Topology PLoS Comput. Biol. 2007 3 e15 10.1371/journal.pcbi.0030015
-
(2007)
PLoS Comput. Biol.
, vol.3
, pp. 15
-
-
Ciliberti, S.1
Martin, O.C.2
Wagner, A.3
-
79
-
-
77955957347
-
Evolution of Characterized Phosphorylation Sites in Budding Yeast
-
10.1093/molbev/msq090
-
A. N. Nguyen Ba A. M. Moses Evolution of Characterized Phosphorylation Sites in Budding Yeast Mol. Biol. Evol. 2010 27 2027 2037 10.1093/molbev/msq090
-
(2010)
Mol. Biol. Evol.
, vol.27
, pp. 2027-2037
-
-
Nguyen Ba, A.N.1
Moses, A.M.2
-
80
-
-
70349526350
-
Comparative Analysis Reveals Conserved Protein Phosphorylation Networks Implicated in Multiple Diseases
-
10.1126/scisignal.2000316
-
C. S. H. Tan B. Bodenmiller A. Pasculescu M. Jovanovic M. O. Hengartner et al. Comparative Analysis Reveals Conserved Protein Phosphorylation Networks Implicated in Multiple Diseases Sci. Signaling 2009 2 ra39 10.1126/scisignal. 2000316
-
(2009)
Sci. Signaling
, vol.2
, pp. 39
-
-
Tan, C.S.H.1
Bodenmiller, B.2
Pasculescu, A.3
Jovanovic, M.4
Hengartner, M.O.5
-
81
-
-
77952986553
-
Deciphering Protein Kinase Specificity Through Large-Scale Analysis of Yeast Phosphorylation Site Motifs
-
10.1126/scisignal.2000482
-
J. Mok P. M. Kim H. Y. K. Lam S. Piccirillo X. Zhou et al. Deciphering Protein Kinase Specificity Through Large-Scale Analysis of Yeast Phosphorylation Site Motifs Sci. Signaling 2010 3 ra12 10.1126/scisignal.2000482
-
(2010)
Sci. Signaling
, vol.3
, pp. 12
-
-
Mok, J.1
Kim, P.M.2
Lam, H.Y.K.3
Piccirillo, S.4
Zhou, X.5
-
82
-
-
61949349758
-
Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90
-
10.1038/nsmb.1565
-
M. Hessling K. Richter J. Buchner Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90 Nat. Struct. Mol. Biol. 2009 16 287 293 10.1038/nsmb.1565
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 287-293
-
-
Hessling, M.1
Richter, K.2
Buchner, J.3
-
83
-
-
43749113194
-
Hydrophilic residues 526 KNDAAD 531 in the flexible C-terminal region of the chaperonin GroEL are critical for substrate protein folding within the central cavity
-
10.1074/jbc.M708002200
-
K. Machida A. Kono-Okada K. Hongo T. Mizobata Y. Kawata Hydrophilic residues 526 KNDAAD 531 in the flexible C-terminal region of the chaperonin GroEL are critical for substrate protein folding within the central cavity J. Biol. Chem. 2008 283 6886 6896 10.1074/jbc.M708002200
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 6886-6896
-
-
MacHida, K.1
Kono-Okada, A.2
Hongo, K.3
Mizobata, T.4
Kawata, Y.5
-
84
-
-
77950597578
-
Intrinsically disordered chaperones in plants and animals
-
10.1139/O09-163
-
P. Tompa D. Kovacs Intrinsically disordered chaperones in plants and animals Biochem. Cell Biol. 2010 88 167 174 10.1139/O09-163
-
(2010)
Biochem. Cell Biol.
, vol.88
, pp. 167-174
-
-
Tompa, P.1
Kovacs, D.2
-
87
-
-
0035022941
-
Intrinsically disordered protein
-
DOI 10.1016/S1093-3263(00)00138-8, PII S1093326300001388
-
A. K. Dunker J. D. Lawson C. J. Brown R. M. Williams P. Romero et al. Intrinsically disordered protein J. Mol. Graphics Modell. 2001 19 26 59 (Pubitemid 32411501)
-
(2001)
Journal of Molecular Graphics and Modelling
, vol.19
, Issue.1
, pp. 26-59
-
-
Dunker, A.K.1
Lawson, J.D.2
Brown, C.J.3
Williams, R.M.4
Romero, P.5
Oh, J.S.6
Oldfield, C.J.7
Campen, A.M.8
Ratliff, C.M.9
Hipps, K.W.10
Ausio, J.11
Nissen, M.S.12
Reeves, R.13
Kang, C.14
Kissinger, C.R.15
Bailey, R.W.16
Griswold, M.D.17
Chiu, W.18
Garner, E.C.19
Obradovic, Z.20
more..
-
88
-
-
0036128797
-
Natively unfolded proteins: A point where biology waits for physics
-
DOI 10.1110/ps.4210102
-
V. N. Uversky Natively unfolded proteins: a point where biology waits for physics Protein Sci. 2002 11 739 756 10.1110/ps.4210102 (Pubitemid 34241284)
-
(2002)
Protein Science
, vol.11
, Issue.4
, pp. 739-756
-
-
Uversky, V.N.1
-
89
-
-
33846099868
-
DisProt: The database of disordered proteins
-
DOI 10.1093/nar/gkl893
-
M. Sickmeier J. A. Hamilton T. LeGall V. Vacic M. S. Cortese et al. DisProt: the Database of Disordered Proteins Nucleic Acids Res. 2007 35 D786 793 10.1093/nar/gkl893 (Pubitemid 46056310)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.SUPPL. 1
-
-
Sickmeier, M.1
Hamilton, J.A.2
LeGall, T.3
Vacic, V.4
Cortese, M.S.5
Tantos, A.6
Szabo, B.7
Tompa, P.8
Chen, J.9
Uversky, V.N.10
Obradovic, Z.11
Dunker, A.K.12
-
90
-
-
67650385638
-
Protein disorder in the human diseasome: Unfoldomics of human genetic diseases
-
10.1186/1471-2164-10-S1-S12
-
U. Midic C. J. Oldfield A. K. Dunker Z. Obradovic V. N. Uversky Protein disorder in the human diseasome: unfoldomics of human genetic diseases BMC Genomics 2009 10 S12 S12 10.1186/1471-2164-10-S1-S12
-
(2009)
BMC Genomics
, vol.10
-
-
Midic, U.1
Oldfield, C.J.2
Dunker, A.K.3
Obradovic, Z.4
Uversky, V.N.5
-
91
-
-
77950618150
-
Molecular simulations of protein disorder
-
10.1139/O09-169
-
S. Rauscher R. Pomès Molecular simulations of protein disorder Biochem. Cell Biol. 2010 88 269 290 10.1139/O09-169
-
(2010)
Biochem. Cell Biol.
, vol.88
, pp. 269-290
-
-
Rauscher, S.1
Pomès, R.2
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