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Volumn , Issue FEB, 2012, Pages

Ghrelin-a pleiotropic hormone secreted from endocrine X/A-like cells of the stomach

Author keywords

Acyl and desacyl; Endocrine cells; Ghrelin; GOAT; Nesfatin 1; Nucb2; Stress

Indexed keywords

ACYLTRANSFERASE; ENDOTOXIN; GAMMA INTERFERON; GHRELIN; GHRELIN RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; OBESTATIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84862234421     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2012.00024     Document Type: Review
Times cited : (68)

References (231)
  • 1
    • 48849107624 scopus 로고    scopus 로고
    • Brain circuits regulating energy homeostasis
    • Abizaid, A., and Horvath, T. L. (2008). Brain circuits regulating energy homeostasis. Regul. Pept. 149, 3-10.
    • (2008) Regul. Pept. , vol.149 , pp. 3-10
    • Abizaid, A.1    Horvath, T.L.2
  • 2
    • 81755172024 scopus 로고    scopus 로고
    • Central mechanisms involved in the orexigenic actions of ghrelin
    • Andrews, Z. B. (2011). Central mechanisms involved in the orexigenic actions of ghrelin. Peptides 32, 2248-2255.
    • (2011) Peptides , vol.32 , pp. 2248-2255
    • Andrews, Z.B.1
  • 5
    • 33751547729 scopus 로고    scopus 로고
    • Brainstem thyrotropin-releasing hormone regulates food intake through vagal-dependent cholinergic stimulation of ghrelin secretion
    • Ao, Y., Go, V. L., Toy, N., Li, T., Wang, Y., Song, M. K., Reeve, J. R. Jr., Liu, Y., and Yang, H. (2006). Brainstem thyrotropin-releasing hormone regulates food intake through vagal-dependent cholinergic stimulation of ghrelin secretion. Endocrinology 147, 6004-6010.
    • (2006) Endocrinology , vol.147 , pp. 6004-6010
    • Ao, Y.1    Go, V.L.2    Toy, N.3    Li, T.4    Wang, Y.5    Song, M.K.6    Reeve Jr., J.R.7    Liu, Y.8    Yang, H.9
  • 6
    • 38149073220 scopus 로고    scopus 로고
    • Ghrelin accelerates gastric emptying via early manifestation of antro-pyloric coordination in conscious rats
    • Ariga, H., Nakade, Y., Tsukamoto, K., Imai, K., Chen, C., Mantyh, C., Pap-pas, T. N., and Takahashi, T. (2008). Ghrelin accelerates gastric emptying via early manifestation of antro-pyloric coordination in conscious rats. Regul. Pept. 146, 112-116.
    • (2008) Regul. Pept. , vol.146 , pp. 112-116
    • Ariga, H.1    Nakade, Y.2    Tsukamoto, K.3    Imai, K.4    Chen, C.5    Mantyh, C.6    Pap-pas, T.N.7    Takahashi, T.8
  • 7
    • 34447550829 scopus 로고    scopus 로고
    • Endogenous acyl ghrelin is involved in mediating spontaneous phase III-like contractions of the rat stomach
    • Ariga, H., Tsukamoto, K., Chen, C., Mantyh, C., Pappas, T. N., and Taka-hashi, T. (2007). Endogenous acyl ghrelin is involved in mediating spontaneous phase III-like contractions of the rat stomach. Neurogas-troenterol. Motil. 19, 675-680.
    • (2007) Neurogas-troenterol. Motil. , vol.19 , pp. 675-680
    • Ariga, H.1    Tsukamoto, K.2    Chen, C.3    Mantyh, C.4    Pappas, T.N.5    Taka-hashi, T.6
  • 10
    • 33751120393 scopus 로고    scopus 로고
    • Gut vagal afferents are not necessary for the eating-stimulatory effect of intraperitoneally injected ghrelin in the rat
    • Arnold, M., Mura, A., Langhans, W., and Geary, N. (2006). Gut vagal afferents are not necessary for the eating-stimulatory effect of intraperitoneally injected ghrelin in the rat. J. Neurosci. 26, 11052-11060.
    • (2006) J. Neurosci. , vol.26 , pp. 11052-11060
    • Arnold, M.1    Mura, A.2    Langhans, W.3    Geary, N.4
  • 14
    • 0036073405 scopus 로고    scopus 로고
    • Extent and direction of ghre-lin transport across the blood-brain barrier is determined by its unique primary structure
    • Banks, W. A., Tschop, M., Robinson, S. M., and Heiman, M. L. (2002). Extent and direction of ghre-lin transport across the blood-brain barrier is determined by its unique primary structure. J. Pharmacol. Exp. Ther. 302, 822-827.
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 822-827
    • Banks, W.A.1    Tschop, M.2    Robinson, S.M.3    Heiman, M.L.4
  • 18
    • 0038054817 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide shifts fasted plasma ghrelin to postprandial levels in rats
    • Basa, N. R., Wang, L., Arteaga, J. R., Heber, D., Livingston, E. H., and Taché, Y. (2003). Bacterial lipopolysaccharide shifts fasted plasma ghrelin to postprandial levels in rats. Neurosci. Lett. 343, 25-28.
    • (2003) Neurosci. Lett. , vol.343 , pp. 25-28
    • Basa, N.R.1    Wang, L.2    Arteaga, J.R.3    Heber, D.4    Livingston, E.H.5    Taché, Y.6
  • 19
    • 0034676324 scopus 로고    scopus 로고
    • Structure-function studies on the new growth hormone-releasing peptide, ghrelin: minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a
    • Bednarek, M. A., Feighner, S. D., Pong, S. S., McKee, K. K., Hreniuk, D. L., Silva, M. V., Warren, V. A., Howard, A. D., Van Der Ploeg, L. H., and Heck, J. V. (2000). Structure-function studies on the new growth hormone-releasing peptide, ghrelin: minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a. J. Med. Chem. 43, 4370-4376.
    • (2000) J. Med. Chem. , vol.43 , pp. 4370-4376
    • Bednarek, M.A.1    Feighner, S.D.2    Pong, S.S.3    McKee, K.K.4    Hreniuk, D.L.5    Silva, M.V.6    Warren, V.A.7    Howard, A.D.8    Van Der Ploeg, L.H.9    Heck, J.V.10
  • 20
  • 23
    • 33846828652 scopus 로고    scopus 로고
    • Intravenous CCK-8, but not GLP-1, suppresses ghrelin and stimulates PYY release in healthy men
    • Brennan, I. M., Otto, B., Feltrin, K. L., Meyer, J. H., Horowitz, M., and Feinle-Bisset, C. (2007). Intravenous CCK-8, but not GLP-1, suppresses ghrelin and stimulates PYY release in healthy men. Peptides 28, 607-611.
    • (2007) Peptides , vol.28 , pp. 607-611
    • Brennan, I.M.1    Otto, B.2    Feltrin, K.L.3    Meyer, J.H.4    Horowitz, M.5    Feinle-Bisset, C.6
  • 25
    • 0842313044 scopus 로고    scopus 로고
    • Desen-sitization and endocytosis mechanisms of ghrelin-activated growth hormone secretagogue receptor 1a
    • Camina, J. P., Carreira, M. C., El Messari, S., Llorens-Cortes, C., Smith, R. G., and Casanueva, F. F. (2004). Desen-sitization and endocytosis mechanisms of ghrelin-activated growth hormone secretagogue receptor 1a. Endocrinology 145, 930-940.
    • (2004) Endocrinology , vol.145 , pp. 930-940
    • Camina, J.P.1    Carreira, M.C.2    El Messari, S.3    Llorens-Cortes, C.4    Smith, R.G.5    Casanueva, F.F.6
  • 28
    • 0041706227 scopus 로고    scopus 로고
    • Therapeutic effects of ghrelin on endotoxic shock in rats
    • Chang, L., Zhao, J., Yang, J., Zhang, Z., Du, J., and Tang, C. (2003b). Therapeutic effects of ghrelin on endotoxic shock in rats. Eur. J. Pharmacol. 473, 171-176.
    • (2003) Eur. J. Pharmacol. , vol.473 , pp. 171-176
    • Chang, L.1    Zhao, J.2    Yang, J.3    Zhang, Z.4    Du, J.5    Tang, C.6
  • 30
    • 73449090824 scopus 로고    scopus 로고
    • Ghre-lin gene products and the regulation of food intake and gut motility
    • Chen, C. Y., Asakawa, A., Fujimiya, M., Lee, S. D., and Inui, A. (2009). Ghre-lin gene products and the regulation of food intake and gut motility. Pharmacol. Rev. 61, 430-481.
    • (2009) Pharmacol. Rev. , vol.61 , pp. 430-481
    • Chen, C.Y.1    Asakawa, A.2    Fujimiya, M.3    Lee, S.D.4    Inui, A.5
  • 32
    • 48349103039 scopus 로고    scopus 로고
    • Ghre-lin attenuates lipopolysaccharide-induced acute lung injury through NO pathway
    • Chen, J., Liu, X., Shu, Q., Li, S., and Luo, F. (2008). Ghre-lin attenuates lipopolysaccharide-induced acute lung injury through NO pathway. Med. Sci. Monit. 14, BR141-BR146.
    • (2008) Med. Sci. Monit. , vol.14
    • Chen, J.1    Liu, X.2    Shu, Q.3    Li, S.4    Luo, F.5
  • 33
    • 77956449473 scopus 로고    scopus 로고
    • Ghrelin inhibits foam cell formation via simultaneously down-regulating the expression of acyl-coenzyme A: cholesterol acyltransferase 1 and up-regulating adenosine triphosphate-binding cassette transporter A1
    • Cheng, B., Wan, J., Wang, Y., Mei, C., Liu, W., Ke, L., and He, P. (2009). Ghrelin inhibits foam cell formation via simultaneously down-regulating the expression of acyl-coenzyme A: cholesterol acyltransferase 1 and up-regulating adenosine triphosphate-binding cassette transporter A1. Car-diovasc. Pathol. 19, e159-e166.
    • (2009) Car-diovasc. Pathol. , vol.19
    • Cheng, B.1    Wan, J.2    Wang, Y.3    Mei, C.4    Liu, W.5    Ke, L.6    He, P.7
  • 34
    • 79952157408 scopus 로고    scopus 로고
    • Ghrelin suppresses inflammation and neuronal nitric oxide synthase in focal cerebral ischemia via the vagus nerve
    • Cheyuo, C., Wu, R., Zhou, M., Jacob, A., Coppa, G., and Wang, P. (2010). Ghrelin suppresses inflammation and neuronal nitric oxide synthase in focal cerebral ischemia via the vagus nerve. Shock 35, 258-265.
    • (2010) Shock , vol.35 , pp. 258-265
    • Cheyuo, C.1    Wu, R.2    Zhou, M.3    Jacob, A.4    Coppa, G.5    Wang, P.6
  • 35
    • 50949098239 scopus 로고    scopus 로고
    • Ghrelin protects against experimental sepsis by inhibiting high-mobility group box 1 release and by killing bacteria
    • Chorny, A., Anderson, P., Gonzalez-Rey, E., and Delgado, M. (2008). Ghrelin protects against experimental sepsis by inhibiting high-mobility group box 1 release and by killing bacteria. J. Immunol. 180, 8369-8377.
    • (2008) J. Immunol. , vol.180 , pp. 8369-8377
    • Chorny, A.1    Anderson, P.2    Gonzalez-Rey, E.3    Delgado, M.4
  • 39
    • 0035433977 scopus 로고    scopus 로고
    • A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    • Cummings, D. E., Purnell, J. Q., Frayo, R. S., Schmidova, K., Wisse, B. E., and Weigle, D. S. (2001). A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 50, 1714-1719.
    • (2001) Diabetes , vol.50 , pp. 1714-1719
    • Cummings, D.E.1    Purnell, J.Q.2    Frayo, R.S.3    Schmidova, K.4    Wisse, B.E.5    Weigle, D.S.6
  • 41
    • 0033679897 scopus 로고    scopus 로고
    • Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans
    • Date, Y., Kojima, M., Hosoda, H., Sawaguchi, A., Mondal, M. S., Sug-anuma, T., Matsukura, S., Kan-gawa, K., and Nakazato, M. (2000). Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 141, 4255-4261.
    • (2000) Endocrinology , vol.141 , pp. 4255-4261
    • Date, Y.1    Kojima, M.2    Hosoda, H.3    Sawaguchi, A.4    Mondal, M.S.5    Sug-anuma, T.6    Matsukura, S.7    Kan-gawa, K.8    Nakazato, M.9
  • 42
    • 0036787457 scopus 로고    scopus 로고
    • The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats
    • Date, Y., Murakami, N., Toshinai, K., Matsukura, S., Niijima, A., Matsuo, H., Kangawa, K., and Nakazato, M. (2002a). The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroenterology 123, 1120-1128.
    • (2002) Gastroenterology , vol.123 , pp. 1120-1128
    • Date, Y.1    Murakami, N.2    Toshinai, K.3    Matsukura, S.4    Niijima, A.5    Matsuo, H.6    Kangawa, K.7    Nakazato, M.8
  • 46
    • 34547652457 scopus 로고    scopus 로고
    • Secretion of ghrelin from rat stomach ghrelin cells in response to local microinfusion of candidate messenger compounds: a microdialysis study
    • de la Cour, C. D., Norlen, P., and Hakan-son, R. (2007). Secretion of ghrelin from rat stomach ghrelin cells in response to local microinfusion of candidate messenger compounds: a microdialysis study. Regul. Pept. 143, 118-126.
    • (2007) Regul. Pept. , vol.143 , pp. 118-126
    • de la Cour, C.D.1    Norlen, P.2    Hakan-son, R.3
  • 48
    • 20344388544 scopus 로고    scopus 로고
    • Comparison of the gastroprokinetic effects of ghre-lin, GHRP-6 and motilin in rats in vivo and in vitro
    • Depoortere, I., De Winter, B., Thijs, T., De Man, J., Pelckmans, P., and Peeters, T. (2005). Comparison of the gastroprokinetic effects of ghre-lin, GHRP-6 and motilin in rats in vivo and in vitro. Eur. J. Pharmacol. 515, 160-168.
    • (2005) Eur. J. Pharmacol. , vol.515 , pp. 160-168
    • Depoortere, I.1    De Winter, B.2    Thijs, T.3    De Man, J.4    Pelckmans, P.5    Peeters, T.6
  • 51
    • 67149146799 scopus 로고    scopus 로고
    • Reduction of T cell-derived ghrelin enhances proinflammatory cytokine expression: implications for age-associated increases in inflammation
    • Dixit, V. D., Yang, H., Cooper-Jenkins, A., Giri, B. B., Patel, K., and Taub, D. D. (2009). Reduction of T cell-derived ghrelin enhances proinflammatory cytokine expression: implications for age-associated increases in inflammation. Blood 113, 5202-5205.
    • (2009) Blood , vol.113 , pp. 5202-5205
    • Dixit, V.D.1    Yang, H.2    Cooper-Jenkins, A.3    Giri, B.B.4    Patel, K.5    Taub, D.D.6
  • 52
    • 2642565900 scopus 로고    scopus 로고
    • Ghrelin stimulates gastric emptying but is without effect on acid secretion and gastric endocrine cells
    • Dornonville de la Cour, C., Lindstrom, E., Norlen, P., and Hakanson, R. (2004). Ghrelin stimulates gastric emptying but is without effect on acid secretion and gastric endocrine cells. Regul. Pept. 120, 23-32.
    • (2004) Regul. Pept. , vol.120 , pp. 23-32
    • Dornonville de la Cour, C.1    Lindstrom, E.2    Norlen, P.3    Hakanson, R.4
  • 54
    • 3142534319 scopus 로고    scopus 로고
    • Ghre-lin stimulates motility in the small intestine of rats through intrinsic cholinergic neurons
    • Edholm, T., Levin, F., Hellstrom, P. M., and Schmidt, P. T. (2004). Ghre-lin stimulates motility in the small intestine of rats through intrinsic cholinergic neurons. Regul. Pept. 121, 25-30.
    • (2004) Regul. Pept. , vol.121 , pp. 25-30
    • Edholm, T.1    Levin, F.2    Hellstrom, P.M.3    Schmidt, P.T.4
  • 55
    • 33847012201 scopus 로고    scopus 로고
    • Involvement of stomach ghrelin and hypothala-mic neuropeptides in tumor necrosis factor-alpha-induced hypophagia in mice
    • Endo, M., Masaki, T., Seike, M., and Yoshimatsu, H. (2007). Involvement of stomach ghrelin and hypothala-mic neuropeptides in tumor necrosis factor-alpha-induced hypophagia in mice. Regul. Pept. 140, 94-100.
    • (2007) Regul. Pept. , vol.140 , pp. 94-100
    • Endo, M.1    Masaki, T.2    Seike, M.3    Yoshimatsu, H.4
  • 56
    • 0141923119 scopus 로고    scopus 로고
    • Cardiovascular and hormonal effects of subcutaneous administration of ghrelin, a novel growth hormone-releasing peptide, in healthy humans
    • Enomoto, M., Nagaya, N., Uematsu, M., Okumura, H., Nakagawa, E., Ono, F., Hosoda, H., Oya, H., Kojima, M., Kanmatsuse, K., and Kangawa, K. (2003). Cardiovascular and hormonal effects of subcutaneous administration of ghrelin, a novel growth hormone-releasing peptide, in healthy humans. Clin. Sci. 105, 431-435.
    • (2003) Clin. Sci. , vol.105 , pp. 431-435
    • Enomoto, M.1    Nagaya, N.2    Uematsu, M.3    Okumura, H.4    Nakagawa, E.5    Ono, F.6    Hosoda, H.7    Oya, H.8    Kojima, M.9    Kanmatsuse, K.10    Kangawa, K.11
  • 61
    • 57349142534 scopus 로고    scopus 로고
    • Reassessment of sst2 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-1
    • Fischer, T., Doll, C., Jacobs, S., Kolodziej, A., Stumm, R., and Schulz, S. (2008). Reassessment of sst2 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-1. J. Clin. Endocrinol. Metab. 93, 4519-4524.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 4519-4524
    • Fischer, T.1    Doll, C.2    Jacobs, S.3    Kolodziej, A.4    Stumm, R.5    Schulz, S.6
  • 63
    • 67349194989 scopus 로고    scopus 로고
    • Effects of ghre-lin on kisspeptin mRNA expression in the hypothalamic medial preoptic area and pulsatile luteinising hormone secretion in the female rat
    • Forbes, S., Li, X. F., Kinsey-Jones, J., and O'Byrne, K. (2009). Effects of ghre-lin on kisspeptin mRNA expression in the hypothalamic medial preoptic area and pulsatile luteinising hormone secretion in the female rat. Neurosci. Lett. 460, 143-147.
    • (2009) Neurosci. Lett. , vol.460 , pp. 143-147
    • Forbes, S.1    Li, X.F.2    Kinsey-Jones, J.3    O'Byrne, K.4
  • 64
    • 0242383502 scopus 로고    scopus 로고
    • Effect of ghrelin and synthetic growth hormone secretagogues in normal and ischemic rat heart
    • Frascarelli, S., Ghelardoni, S., Ronca-Testoni, S., and Zucchi, R. (2003). Effect of ghrelin and synthetic growth hormone secretagogues in normal and ischemic rat heart. Basic Res. Cardiol. 98, 401-405.
    • (2003) Basic Res. Cardiol. , vol.98 , pp. 401-405
    • Frascarelli, S.1    Ghelardoni, S.2    Ronca-Testoni, S.3    Zucchi, R.4
  • 65
    • 0037592273 scopus 로고    scopus 로고
    • Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats
    • Fujino, K., Inui, A., Asakawa, A., Kihara, N., Fujimura, M., and Fujimiya, M. (2003). Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats. J. Physiol. (Lond.) 550, 227-240.
    • (2003) J. Physiol. (Lond.) , vol.550 , pp. 227-240
    • Fujino, K.1    Inui, A.2    Asakawa, A.3    Kihara, N.4    Fujimura, M.5    Fujimiya, M.6
  • 66
    • 10644280945 scopus 로고    scopus 로고
    • Ghrelin enhances gastric motility through direct stimulation of intrinsic neural pathways and capsaicin-sensitive afferent neurones in rats
    • Fukuda, H., Mizuta, Y., Isomoto, H., Takeshima, F., Ohnita, K., Ohba, K., Omagari, K., Taniyama, K., and Kohno, S. (2004). Ghrelin enhances gastric motility through direct stimulation of intrinsic neural pathways and capsaicin-sensitive afferent neurones in rats. Scand. J. Gastroenterol. 39, 1209-1214.
    • (2004) Scand. J. Gastroenterol. , vol.39 , pp. 1209-1214
    • Fukuda, H.1    Mizuta, Y.2    Isomoto, H.3    Takeshima, F.4    Ohnita, K.5    Ohba, K.6    Omagari, K.7    Taniyama, K.8    Kohno, S.9
  • 67
    • 0035834586 scopus 로고    scopus 로고
    • Intracerebroventricular administration of ghrelin rapidly suppresses pulsatile luteinizing hormone secretion in ovariectomized rats
    • Furuta, M., Funabashi, T., and Kimura, F. (2001). Intracerebroventricular administration of ghrelin rapidly suppresses pulsatile luteinizing hormone secretion in ovariectomized rats. Biochem. Biophys. Res. Com-mun. 288, 780-785.
    • (2001) Biochem. Biophys. Res. Com-mun. , vol.288 , pp. 780-785
    • Furuta, M.1    Funabashi, T.2    Kimura, F.3
  • 71
    • 72549108065 scopus 로고    scopus 로고
    • Continued controversy on obestatin as a gut hormone influencing food intake and gastrointestinal motility
    • Goebel, M., Stengel, A., and Taché, Y. (2008). Continued controversy on obestatin as a gut hormone influencing food intake and gastrointestinal motility. Obes. Metab. 4, 143-148.
    • (2008) Obes. Metab. , vol.4 , pp. 143-148
    • Goebel, M.1    Stengel, A.2    Taché, Y.3
  • 73
    • 66449131125 scopus 로고    scopus 로고
    • Expression and modulation of ghre-lin O-acyltransferase in cultured chondrocytes
    • Gomez, R., Lago, F., Gomez-Reino, J. J., Dieguez, C., and Gualillo, O. (2009). Expression and modulation of ghre-lin O-acyltransferase in cultured chondrocytes. Arthritis Rheum. 60, 1704-1709.
    • (2009) Arthritis Rheum , vol.60 , pp. 1704-1709
    • Gomez, R.1    Lago, F.2    Gomez-Reino, J.J.3    Dieguez, C.4    Gualillo, O.5
  • 74
    • 57749084282 scopus 로고    scopus 로고
    • Influence of chronic under nutrition and leptin on GOAT mRNA levels in rat stomach mucosa
    • Gonzalez, C. R., Vazquez, M. J., Lopez, M., and Dieguez, C. (2008). Influence of chronic under nutrition and leptin on GOAT mRNA levels in rat stomach mucosa. J. Mol. Endocrinol. 41, 415-421.
    • (2008) J. Mol. Endocrinol. , vol.41 , pp. 415-421
    • Gonzalez, C.R.1    Vazquez, M.J.2    Lopez, M.3    Dieguez, C.4
  • 75
    • 33645069631 scopus 로고    scopus 로고
    • Therapeutic action of ghrelin in a mouse model of colitis
    • Gonzalez-Rey, E., Chorny, A., and Delgado, M. (2006). Therapeutic action of ghrelin in a mouse model of colitis. Gastroenterology 130, 1707-1720.
    • (2006) Gastroenterology , vol.130 , pp. 1707-1720
    • Gonzalez-Rey, E.1    Chorny, A.2    Delgado, M.3
  • 76
  • 77
    • 33644669037 scopus 로고    scopus 로고
    • Ghrelin receptor agonist GHRP-2 prevents arthritis-induced increase in E3 ubiquitin-ligating enzymes MuRF1 and MAFbx gene expression in skeletal muscle
    • Granado, M., Priego, T., Martin, A. I., Villanua, M. A., and Lopez-Calderon, A. (2005b). Ghrelin receptor agonist GHRP-2 prevents arthritis-induced increase in E3 ubiquitin-ligating enzymes MuRF1 and MAFbx gene expression in skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 289, E1007-E1014.
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.289
    • Granado, M.1    Priego, T.2    Martin, A.I.3    Villanua, M.A.4    Lopez-Calderon, A.5
  • 78
    • 49749084909 scopus 로고    scopus 로고
    • Distribution of obestatin and ghrelin in human tissues: immunoreactive cells in the gastrointestinal tract, pancreas, and mammary glands
    • Gronberg, M., Tsolakis, A. V., Mag-nusson, L., Janson, E. T., and Saras, J. (2008). Distribution of obestatin and ghrelin in human tissues: immunoreactive cells in the gastrointestinal tract, pancreas, and mammary glands. J. Histochem. Cytochem. 56, 793-801.
    • (2008) J. Histochem. Cytochem. , vol.56 , pp. 793-801
    • Gronberg, M.1    Tsolakis, A.V.2    Mag-nusson, L.3    Janson, E.T.4    Saras, J.5
  • 79
    • 0842330725 scopus 로고    scopus 로고
    • Synaptic interactions between ghrelin- and neuropep-tide Y-containing neurons in the rat arcuate nucleus
    • Guan, J. L., Wang, Q. P., Kageyama, H., Takenoya, F., Kita, T., Mat-suoka, T., Funahashi, H., and Shioda, S. (2003). Synaptic interactions between ghrelin- and neuropep-tide Y-containing neurons in the rat arcuate nucleus. Peptides 24, 1921-1928.
    • (2003) Peptides , vol.24 , pp. 1921-1928
    • Guan, J.L.1    Wang, Q.P.2    Kageyama, H.3    Takenoya, F.4    Kita, T.5    Mat-suoka, T.6    Funahashi, H.7    Shioda, S.8
  • 83
    • 34547650656 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 (GLP-1) suppresses ghre-lin levels in humans via increased insulin secretion
    • Hagemann, D., Holst, J. J., Gethmann, A., Banasch, M., Schmidt, W. E., and Meier, J. J. (2007). Glucagon-like peptide 1 (GLP-1) suppresses ghre-lin levels in humans via increased insulin secretion. Regul. Pept. 143, 64-68.
    • (2007) Regul. Pept. , vol.143 , pp. 64-68
    • Hagemann, D.1    Holst, J.J.2    Gethmann, A.3    Banasch, M.4    Schmidt, W.E.5    Meier, J.J.6
  • 84
    • 0344394263 scopus 로고    scopus 로고
    • Alterations of plasma ghrelin levels in rats with lipopolysaccharide-induced wasting syndrome and effects of ghre-lin treatment on the syndrome
    • Hataya, Y., Akamizu, T., Hosoda, H., Kanamoto, N., Moriyama, K., Kangawa, K., Takaya, K., and Nakao, K. (2003). Alterations of plasma ghrelin levels in rats with lipopolysaccharide-induced wasting syndrome and effects of ghre-lin treatment on the syndrome. Endocrinology 144, 5365-5371.
    • (2003) Endocrinology , vol.144 , pp. 5365-5371
    • Hataya, Y.1    Akamizu, T.2    Hosoda, H.3    Kanamoto, N.4    Moriyama, K.5    Kangawa, K.6    Takaya, K.7    Nakao, K.8
  • 85
    • 67349116804 scopus 로고    scopus 로고
    • Expression, regulation and biological actions of growth hormone (GH) and ghrelin in the immune system
    • Hattori, N. (2009). Expression, regulation and biological actions of growth hormone (GH) and ghrelin in the immune system. Growth Horm. IGF Res. 19, 187-197.
    • (2009) Growth Horm. IGF Res. , vol.19 , pp. 187-197
    • Hattori, N.1
  • 86
    • 0034841199 scopus 로고    scopus 로고
    • GH, GH receptor, GH secretagogue receptor, and ghrelin expression in human T cells, B cells, and neutrophils
    • Hattori, N., Saito, T., Yagyu, T., Jiang, B. H., Kitagawa, K., and Inagaki, C. (2001). GH, GH receptor, GH secretagogue receptor, and ghrelin expression in human T cells, B cells, and neutrophils. J. Clin. Endocrinol. Metab. 86, 4284-4291.
    • (2001) J. Clin. Endocrinol. Metab , vol.86 , pp. 4284-4291
    • Hattori, N.1    Saito, T.2    Yagyu, T.3    Jiang, B.H.4    Kitagawa, K.5    Inagaki, C.6
  • 88
    • 38149043415 scopus 로고    scopus 로고
    • The autonomic nervous system regulates gastric ghrelin secretion in rats
    • Hosoda, H., and Kangawa, K. (2008). The autonomic nervous system regulates gastric ghrelin secretion in rats. Regul. Pept. 146, 12-18.
    • (2008) Regul. Pept. , vol.146 , pp. 12-18
    • Hosoda, H.1    Kangawa, K.2
  • 89
    • 0034731310 scopus 로고    scopus 로고
    • Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue
    • Hosoda, H., Kojima, M., Matsuo, H., and Kangawa, K. (2000). Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochem. Bio-phys. Res. Commun. 279, 909-913.
    • (2000) Biochem. Bio-phys. Res. Commun. , vol.279 , pp. 909-913
    • Hosoda, H.1    Kojima, M.2    Matsuo, H.3    Kangawa, K.4
  • 91
    • 70449656984 scopus 로고    scopus 로고
    • Ghrelin inhibits post-infarct myocardial remodeling and improves cardiac function through anti-inflammation effect
    • Huang, C. X., Yuan, M. J., Huang, H., Wu, G., Liu, Y., Yu, S. B., Li, H. T., and Wang, T. (2009). Ghrelin inhibits post-infarct myocardial remodeling and improves cardiac function through anti-inflammation effect. Peptides 30, 2286-2291.
    • (2009) Peptides , vol.30 , pp. 2286-2291
    • Huang, C.X.1    Yuan, M.J.2    Huang, H.3    Wu, G.4    Liu, Y.5    Yu, S.B.6    Li, H.T.7    Wang, T.8
  • 92
    • 38149036543 scopus 로고    scopus 로고
    • Ghrelin alleviates biliary obstruction-induced chronic hepatic injury in rats
    • Iseri, S. O., Sener, G., Saglam, B., Ercan, F., Gedik, N., and Yegen, B. C. (2008). Ghrelin alleviates biliary obstruction-induced chronic hepatic injury in rats. Regul. Pept. 146, 73-79.
    • (2008) Regul. Pept. , vol.146 , pp. 73-79
    • Iseri, S.O.1    Sener, G.2    Saglam, B.3    Ercan, F.4    Gedik, N.5    Yegen, B.C.6
  • 95
    • 70549083583 scopus 로고    scopus 로고
    • The inhibitory effect of ghrelin on sepsis-induced inflammation is mediated by the MAPK phosphatase-1
    • Jacob, A., Rajan, D., Pathickal, B., Balouch, I., Hartman, A., Wu, R., Zhou, M., and Wang, P. (2010). The inhibitory effect of ghrelin on sepsis-induced inflammation is mediated by the MAPK phosphatase-1. Int. J. Mol. Med. 25, 159-164.
    • (2010) Int. J. Mol. Med. , vol.25 , pp. 159-164
    • Jacob, A.1    Rajan, D.2    Pathickal, B.3    Balouch, I.4    Hartman, A.5    Wu, R.6    Zhou, M.7    Wang, P.8
  • 96
    • 79955938127 scopus 로고    scopus 로고
    • Endocrine impact of Helicobacter pylori: focus on ghrelin and ghre-lin O-acyltransferase
    • Jeffery, P. L., McGuckin, M. A., and Linden, S. K. (2011). Endocrine impact of Helicobacter pylori: focus on ghrelin and ghre-lin O-acyltransferase. World J. Gastroenterol. 17, 1249-1260.
    • (2011) World J. Gastroenterol. , vol.17 , pp. 1249-1260
    • Jeffery, P.L.1    McGuckin, M.A.2    Linden, S.K.3
  • 97
    • 8744303926 scopus 로고    scopus 로고
    • Changes in plasma ghre-lin concentration immediately after gastrectomy in patients with early gastric cancer
    • Jeon, T. Y., Lee, S., Kim, H. H., Kim, Y. J., Son, H. C., Kim, D. H., and Sim, M. S. (2004). Changes in plasma ghre-lin concentration immediately after gastrectomy in patients with early gastric cancer. J. Clin. Endocrinol. Metab. 89, 5392-5396.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 5392-5396
    • Jeon, T.Y.1    Lee, S.2    Kim, H.H.3    Kim, Y.J.4    Son, H.C.5    Kim, D.H.6    Sim, M.S.7
  • 98
    • 33746583963 scopus 로고    scopus 로고
    • Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue recep-tor/dopamine receptor subtype 1 heterodimers
    • Jiang, H., Betancourt, L., and Smith, R. G. (2006). Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue recep-tor/dopamine receptor subtype 1 heterodimers. Mol. Endocrinol. 20, 1772-1785.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 1772-1785
    • Jiang, H.1    Betancourt, L.2    Smith, R.G.3
  • 100
    • 80051740293 scopus 로고    scopus 로고
    • Ghrelin stimulates corticotropin-releasing factor and vasopressin gene expression in rat hypothalamic 4B cells
    • Kageyama, K., Kumata, Y., Akimoto, K., Takayasu, S., Tamasawa, N., and Suda, T. (2011). Ghrelin stimulates corticotropin-releasing factor and vasopressin gene expression in rat hypothalamic 4B cells. Stress 14, 520-529.
    • (2011) Stress , vol.14 , pp. 520-529
    • Kageyama, K.1    Kumata, Y.2    Akimoto, K.3    Takayasu, S.4    Tamasawa, N.5    Suda, T.6
  • 101
    • 0035513696 scopus 로고    scopus 로고
    • Chronic central infusion of ghrelin increases hypo-thalamic neuropeptideY and agouti-related protein mRNA levels and body weight in rats
    • Kamegai, J., Tamura, H., Shimizu, T., Ishii, S., Sugihara, H., and Wak-abayashi, I. (2001). Chronic central infusion of ghrelin increases hypo-thalamic neuropeptideY and agouti-related protein mRNA levels and body weight in rats. Diabetes 50, 2438-2443.
    • (2001) Diabetes , vol.50 , pp. 2438-2443
    • Kamegai, J.1    Tamura, H.2    Shimizu, T.3    Ishii, S.4    Sugihara, H.5    Wak-abayashi, I.6
  • 102
    • 0042200265 scopus 로고    scopus 로고
    • Changes in ghrelin and ghrelin receptor expression according to feeding status
    • Kim, M. S., Yoon, C. Y., Park, K. H., Shin, C. S., Park, K. S., Kim, S. Y., Cho, B. Y., and Lee, H. K. (2003). Changes in ghrelin and ghrelin receptor expression according to feeding status. Neuroreport 14, 1317-1320.
    • (2003) Neuroreport , vol.14 , pp. 1317-1320
    • Kim, M.S.1    Yoon, C.Y.2    Park, K.H.3    Shin, C.S.4    Park, K.S.5    Kim, S.Y.6    Cho, B.Y.7    Lee, H.K.8
  • 105
    • 22644444107 scopus 로고    scopus 로고
    • Gastric motor effects of pep-tide and non-peptide ghrelin agonists in mice in vivo and in vitro
    • Kitazawa, T., De Smet, B., Verbeke, K., Depoortere, I., and Peeters, T. L. (2005). Gastric motor effects of pep-tide and non-peptide ghrelin agonists in mice in vivo and in vitro. Gut 54, 1078-1084.
    • (2005) Gut , vol.54 , pp. 1078-1084
    • Kitazawa, T.1    De Smet, B.2    Verbeke, K.3    Depoortere, I.4    Peeters, T.L.5
  • 106
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima, M., Hosoda, H., Date, Y., Nakazato, M., Matsuo, H., and Kan-gawa, K. (1999). Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402, 656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kan-gawa, K.6
  • 107
    • 15544385058 scopus 로고    scopus 로고
    • Ghrelin: structure and function
    • Kojima, M., and Kangawa, K. (2005). Ghrelin: structure and function. Physiol. Rev. 85, 495-522.
    • (2005) Physiol. Rev. , vol.85 , pp. 495-522
    • Kojima, M.1    Kangawa, K.2
  • 108
    • 81755173376 scopus 로고    scopus 로고
    • The discovery of ghrelin: with a little luck and great passion. Preface
    • Kojima, M., and Kangawa, K. (2011). The discovery of ghrelin: with a little luck and great passion. Preface. Peptides 32, 2153-2154.
    • (2011) Peptides , vol.32 , pp. 2153-2154
    • Kojima, M.1    Kangawa, K.2
  • 111
    • 0030152059 scopus 로고    scopus 로고
    • Bacterial products and the control of ingestive behavior: clinical implications
    • Langhans, W. (1996). Bacterial products and the control of ingestive behavior: clinical implications. Nutrition 12, 303-315.
    • (1996) Nutrition , vol.12 , pp. 303-315
    • Langhans, W.1
  • 112
    • 0033781059 scopus 로고    scopus 로고
    • Anorexia of infection: current prospects
    • Langhans, W. (2000). Anorexia of infection: current prospects. Nutrition 16, 996-1005.
    • (2000) Nutrition , vol.16 , pp. 996-1005
    • Langhans, W.1
  • 115
    • 77956209223 scopus 로고    scopus 로고
    • Growth hormone releasing peptide-2, a ghrelin agonist, attenuates lipopolysaccharide-induced acute lung injury in rats
    • Li, G., Li, J., Zhou, Q., Song, X., Liang, H., and Huang, L. (2010). Growth hormone releasing peptide-2, a ghrelin agonist, attenuates lipopolysaccharide-induced acute lung injury in rats. Tohoku J. Exp. Med. 222, 7-13.
    • (2010) Tohoku J. Exp. Med. , vol.222 , pp. 7-13
    • Li, G.1    Li, J.2    Zhou, Q.3    Song, X.4    Liang, H.5    Huang, L.6
  • 117
    • 2342620868 scopus 로고    scopus 로고
    • Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats
    • Lin, Y., Matsumura, K., Fukuhara, M., Kagiyama, S., Fujii, K., and Iida, M. (2004). Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats. Hypertension 43, 977-982.
    • (2004) Hypertension , vol.43 , pp. 977-982
    • Lin, Y.1    Matsumura, K.2    Fukuhara, M.3    Kagiyama, S.4    Fujii, K.5    Iida, M.6
  • 118
    • 1842735215 scopus 로고    scopus 로고
    • Effect of GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach
    • Lippl, F., Kircher, F., Erdmann, J., Allescher, H. D., and Schusdziarra, V. (2004). Effect of GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach. Regul. Pept. 119, 93-98.
    • (2004) Regul. Pept. , vol.119 , pp. 93-98
    • Lippl, F.1    Kircher, F.2    Erdmann, J.3    Allescher, H.D.4    Schusdziarra, V.5
  • 125
    • 32244443040 scopus 로고    scopus 로고
    • Ghrelin and lep-tin elevation in postoperative intra-abdominal sepsis
    • Maruna, P., Gurlich, R., Frasko, R., and Rosicka, M. (2005). Ghrelin and lep-tin elevation in postoperative intra-abdominal sepsis. Eur. Surg. Res. 37, 354-359.
    • (2005) Eur. Surg. Res. , vol.37 , pp. 354-359
    • Maruna, P.1    Gurlich, R.2    Frasko, R.3    Rosicka, M.4
  • 126
    • 47049108187 scopus 로고    scopus 로고
    • Ghrelin as an acute-phase reactant during postoperative stress response
    • Maruna, P., Gurlich, R., and Rosicka, M. (2008). Ghrelin as an acute-phase reactant during postoperative stress response. Horm. Metab. Res. 40, 404-409.
    • (2008) Horm. Metab. Res. , vol.40 , pp. 404-409
    • Maruna, P.1    Gurlich, R.2    Rosicka, M.3
  • 130
    • 33646769934 scopus 로고    scopus 로고
    • Direct stimulation of ghrelin secretion by sympathetic nerves
    • Mundinger, T. O., Cummings, D. E., and Taborsky, G. J. Jr. (2006). Direct stimulation of ghrelin secretion by sympathetic nerves. Endocrinology 147, 2893-2901.
    • (2006) Endocrinology , vol.147 , pp. 2893-2901
    • Mundinger, T.O.1    Cummings, D.E.2    Taborsky Jr., G.J.3
  • 131
    • 27744441026 scopus 로고    scopus 로고
    • Ghrelin enhances gastric emptying in diabetic gastroparesis: a double blind, placebo controlled, crossover study
    • Murray, C. D., Martin, N. M., Patterson, M., Taylor, S. A., Ghatei, M. A., Kamm, M. A., Johnston, C., Bloom, S. R., and Emmanuel, A. V. (2005). Ghrelin enhances gastric emptying in diabetic gastroparesis: a double blind, placebo controlled, crossover study. Gut 54, 1693-1698.
    • (2005) Gut , vol.54 , pp. 1693-1698
    • Murray, C.D.1    Martin, N.M.2    Patterson, M.3    Taylor, S.A.4    Ghatei, M.A.5    Kamm, M.A.6    Johnston, C.7    Bloom, S.R.8    Emmanuel, A.V.9
  • 133
    • 0035908954 scopus 로고    scopus 로고
    • Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure
    • Nagaya, N., Uematsu, M., Kojima, M., Ikeda, Y., Yoshihara, F., Shimizu, W., Hosoda, H., Hirota, Y., Ishida, H., Mori, H., and Kangawa, K. (2001b). Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure. Circulation 104, 1430-1435.
    • (2001) Circulation , vol.104 , pp. 1430-1435
    • Nagaya, N.1    Uematsu, M.2    Kojima, M.3    Ikeda, Y.4    Yoshihara, F.5    Shimizu, W.6    Hosoda, H.7    Hirota, Y.8    Ishida, H.9    Mori, H.10    Kangawa, K.11
  • 134
    • 20844460120 scopus 로고    scopus 로고
    • Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure
    • Nagaya, N., Moriya, J., Yasumura, Y., Uematsu, M., Ono, F., Shimizu, W., Ueno, K., Kitakaze, M., Miyatake, K., and Kangawa, K. (2004). Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure. Circulation 110, 3674-3679.
    • (2004) Circulation , vol.110 , pp. 3674-3679
    • Nagaya, N.1    Moriya, J.2    Yasumura, Y.3    Uematsu, M.4    Ono, F.5    Shimizu, W.6    Ueno, K.7    Kitakaze, M.8    Miyatake, K.9    Kangawa, K.10
  • 141
    • 33645420927 scopus 로고    scopus 로고
    • Differential BBB interactions of three ingestive peptides: obestatin, ghrelin, and adiponectin
    • Pan, W., Tu, H., and Kastin, A. J. (2006). Differential BBB interactions of three ingestive peptides: obestatin, ghrelin, and adiponectin. Peptides 27, 911-916.
    • (2006) Peptides , vol.27 , pp. 911-916
    • Pan, W.1    Tu, H.2    Kastin, A.J.3
  • 143
    • 77955747334 scopus 로고    scopus 로고
    • Altered metabolic and neuro-chemical responses to chronic unpredictable stressors in ghrelin receptor-deficient mice
    • Patterson, Z. R., Ducharme, R., Anis-man, H., and Abizaid, A. (2010). Altered metabolic and neuro-chemical responses to chronic unpredictable stressors in ghrelin receptor-deficient mice. Eur. J. Neurosci. 32, 632-639.
    • (2010) Eur. J. Neurosci. , vol.32 , pp. 632-639
    • Patterson, Z.R.1    Ducharme, R.2    Anis-man, H.3    Abizaid, A.4
  • 145
    • 0036803889 scopus 로고    scopus 로고
    • Natural (ghrelin) and synthetic (hexarelin) GH secretagogues stimulate H9c2 cardiomyocyte cell proliferation
    • Pettersson, I., Muccioli, G., Granata, R., Deghenghi, R., Ghigo, E., Ohlsson, C., and Isgaard, J. (2002). Natural (ghrelin) and synthetic (hexarelin) GH secretagogues stimulate H9c2 cardiomyocyte cell proliferation. J. Endocrinol. 175, 201-209.
    • (2002) J. Endocrinol. , vol.175 , pp. 201-209
    • Pettersson, I.1    Muccioli, G.2    Granata, R.3    Deghenghi, R.4    Ghigo, E.5    Ohlsson, C.6    Isgaard, J.7
  • 147
    • 0042205288 scopus 로고    scopus 로고
    • Total and active ghrelin in developing rats during hypoxia
    • Raff, H. (2003). Total and active ghrelin in developing rats during hypoxia. Endocrine 21, 159-161.
    • (2003) Endocrine , vol.21 , pp. 159-161
    • Raff, H.1
  • 148
    • 77956294057 scopus 로고    scopus 로고
    • Psy-chosocial stressor effects on corti-sol and ghrelin in emotional and non-emotional eaters: influence of anger and shame
    • Raspopow, K., Abizaid, A., Matheson, K., and Anisman, H. (2010). Psy-chosocial stressor effects on corti-sol and ghrelin in emotional and non-emotional eaters: influence of anger and shame. Horm. Behav. 58, 677-684.
    • (2010) Horm. Behav. , vol.58 , pp. 677-684
    • Raspopow, K.1    Abizaid, A.2    Matheson, K.3    Anisman, H.4
  • 149
    • 2342606044 scopus 로고    scopus 로고
    • The "normal" endocrine cell of the gut: changing concepts and new evidences
    • Rindi, G., Leiter, A. B., Kopin, A. S., Bordi, C., and Solcia, E. (2004). The "normal" endocrine cell of the gut: changing concepts and new evidences. Ann. N. Y. Acad. Sci. 1014, 1-12.
    • (2004) Ann. N. Y. Acad. Sci. , vol.1014 , pp. 1-12
    • Rindi, G.1    Leiter, A.B.2    Kopin, A.S.3    Bordi, C.4    Solcia, E.5
  • 152
    • 34347359491 scopus 로고    scopus 로고
    • The acute ghrelin response to a psychological stress challenge does not predict the post-stress urge to eat
    • Rouach, V., Bloch, M., Rosenberg, N., Gilad, S., Limor, R., Stern, N., and Greenman, Y. (2007). The acute ghrelin response to a psychological stress challenge does not predict the post-stress urge to eat. Psychoneu-roendocrinology 32, 693-702.
    • (2007) Psychoneu-roendocrinology , vol.32 , pp. 693-702
    • Rouach, V.1    Bloch, M.2    Rosenberg, N.3    Gilad, S.4    Limor, R.5    Stern, N.6    Greenman, Y.7
  • 154
    • 0036171253 scopus 로고    scopus 로고
    • Ghrelin-producing cells exist as two types of cells, closed- and opened-type cells, in the rat gastrointestinal tract
    • Sakata, I., Nakamura, K., Yamazaki, M., Matsubara, M., Hayashi, Y., Kan-gawa, K., and Sakai, T. (2002). Ghrelin-producing cells exist as two types of cells, closed- and opened-type cells, in the rat gastrointestinal tract. Peptides 23, 531-536.
    • (2002) Peptides , vol.23 , pp. 531-536
    • Sakata, I.1    Nakamura, K.2    Yamazaki, M.3    Matsubara, M.4    Hayashi, Y.5    Kan-gawa, K.6    Sakai, T.7
  • 155
    • 0038031634 scopus 로고    scopus 로고
    • Growth hormone secre-tagogue receptor expression in the cells of the stomach-projected afferent nerve in the rat nodose ganglion
    • Sakata, I., Yamazaki, M., Inoue, K., Hayashi, Y., Kangawa, K., and Sakai, T. (2003). Growth hormone secre-tagogue receptor expression in the cells of the stomach-projected afferent nerve in the rat nodose ganglion. Neurosci. Lett. 342, 183-186.
    • (2003) Neurosci. Lett. , vol.342 , pp. 183-186
    • Sakata, I.1    Yamazaki, M.2    Inoue, K.3    Hayashi, Y.4    Kangawa, K.5    Sakai, T.6
  • 156
    • 79958088475 scopus 로고    scopus 로고
    • The prokinetic face of ghrelin
    • Sallam, H. S., and Chen, J. D. (2010). The prokinetic face of ghrelin. Int. J. Pept. 2010, 1-11.
    • (2010) Int. J. Pept. , vol.2010 , pp. 1-11
    • Sallam, H.S.1    Chen, J.D.2
  • 159
    • 71849109389 scopus 로고    scopus 로고
    • Lean mean fat reducing "ghrelin" machine: hypothala-mic ghrelin and ghrelin receptors as therapeutic targets in obesity
    • Schellekens, H., Dinan, T. G., and Cryan, J. F. (2010). Lean mean fat reducing "ghrelin" machine: hypothala-mic ghrelin and ghrelin receptors as therapeutic targets in obesity. Neu-ropharmacology 58, 2-16.
    • (2010) Neu-ropharmacology , vol.58 , pp. 2-16
    • Schellekens, H.1    Dinan, T.G.2    Cryan, J.F.3
  • 163
    • 68449094576 scopus 로고    scopus 로고
    • Nesfatin-1: an overview and future clinical application
    • Shimizu, H., Oh, I. S., Okada, S., and Mori, M. (2009). Nesfatin-1: an overview and future clinical application. Endocr. J. 56, 537-543.
    • (2009) Endocr. J. , vol.56 , pp. 537-543
    • Shimizu, H.1    Oh, I.S.2    Okada, S.3    Mori, M.4
  • 164
    • 33748916666 scopus 로고    scopus 로고
    • Evidence that stimulation of ghrelin receptors in the spinal cord initiates propulsive activity inthe colonof the rat
    • Shimizu, Y., Chang, E. C., Shafton, A. D., Ferens, D. M., Sanger, G. J., Wither-ington, J., and Furness, J. B. (2006). Evidence that stimulation of ghrelin receptors in the spinal cord initiates propulsive activity inthe colonof the rat. J. Physiol. (Lond.) 576, 329-338.
    • (2006) J. Physiol. (Lond.) , vol.576 , pp. 329-338
    • Shimizu, Y.1    Chang, E.C.2    Shafton, A.D.3    Ferens, D.M.4    Sanger, G.J.5    Wither-ington, J.6    Furness, J.B.7
  • 166
    • 20044368268 scopus 로고    scopus 로고
    • Differential effects of sham feeding and meal ingestion on ghrelin and pancreatic polypeptide levels: evidence for vagal efferent stimulation mediating ghrelin release
    • Simonian, H. P., Kresge, K. M., Boden, G. H., and Parkman, H. P. (2005). Differential effects of sham feeding and meal ingestion on ghrelin and pancreatic polypeptide levels: evidence for vagal efferent stimulation mediating ghrelin release. Neurogas-troenterol. Motil. 17, 348-354.
    • (2005) Neurogas-troenterol. Motil. , vol.17 , pp. 348-354
    • Simonian, H.P.1    Kresge, K.M.2    Boden, G.H.3    Parkman, H.P.4
  • 167
    • 81755161533 scopus 로고    scopus 로고
    • Ghrelin and food reward: the story of potential underlying substrates
    • Skibicka, K. P., and Dickson, S. L. (2011). Ghrelin and food reward: the story of potential underlying substrates. Peptides 32, 2265-2273.
    • (2011) Peptides , vol.32 , pp. 2265-2273
    • Skibicka, K.P.1    Dickson, S.L.2
  • 168
    • 44649098808 scopus 로고    scopus 로고
    • Ghrelin, des-acyl ghrelin and obestatin: three pieces of the same puzzle
    • Soares, J. B., and Leite-Moreira, A. F. (2008). Ghrelin, des-acyl ghrelin and obestatin: three pieces of the same puzzle. Peptides 29, 1255-1270.
    • (2008) Peptides , vol.29 , pp. 1255-1270
    • Soares, J.B.1    Leite-Moreira, A.F.2
  • 170
    • 78049457734 scopus 로고    scopus 로고
    • Cold ambient temperature reverses abdominal surgery-induced delayed gastric emptying and decreased plasma ghrelin levels in rats
    • Stengel, A., Goebel, M., Luckey, A., Yuan, P. Q., Wang, L., and Taché, Y. (2010a). Cold ambient temperature reverses abdominal surgery-induced delayed gastric emptying and decreased plasma ghrelin levels in rats. Peptides 31, 2229-2235.
    • (2010) Peptides , vol.31 , pp. 2229-2235
    • Stengel, A.1    Goebel, M.2    Luckey, A.3    Yuan, P.Q.4    Wang, L.5    Taché, Y.6
  • 171
    • 77955654331 scopus 로고    scopus 로고
    • Lipopolysaccharide differentially decreases plasma acyl and desacyl ghrelin levels in rats: potential role of the circulating ghrelin-acylating enzyme GOAT
    • Stengel, A., Goebel, M., Wang, L., Reeve, J. R. Jr., Taché, Y., and Lambrecht, N. W. (2010b). Lipopolysaccharide differentially decreases plasma acyl and desacyl ghrelin levels in rats: potential role of the circulating ghrelin-acylating enzyme GOAT. Peptides 31, 1689-1696.
    • (2010) Peptides , vol.31 , pp. 1689-1696
    • Stengel, A.1    Goebel, M.2    Wang, L.3    Reeve Jr., J.R.4    Taché, Y.5    Lambrecht, N.W.6
  • 172
    • 74149087844 scopus 로고    scopus 로고
    • Ghrelin, des-acyl ghrelin and nesfatin-1 in gastric X/A-like cells: role as regulators of food intake and body weight
    • Stengel, A., Goebel, M., Wang, L., and Taché, Y. (2010c). Ghrelin, des-acyl ghrelin and nesfatin-1 in gastric X/A-like cells: role as regulators of food intake and body weight. Pep-tides 31, 357-369.
    • (2010) Pep-tides , vol.31 , pp. 357-369
    • Stengel, A.1    Goebel, M.2    Wang, L.3    Taché, Y.4
  • 173
    • 75049085779 scopus 로고    scopus 로고
    • Differential distribution of ghrelin-O-acyltransferase (GOAT) immunoreactive cells in the mouse and rat gastric oxyn-tic mucosa
    • Stengel, A., Goebel, M., Wang, L., Taché, Y., Sachs, G., and Lambrecht, N. W. (2010d). Differential distribution of ghrelin-O-acyltransferase (GOAT) immunoreactive cells in the mouse and rat gastric oxyn-tic mucosa. Biochem. Biophys. Res. Commun. 392, 67-71.
    • (2010) Biochem. Biophys. Res. Commun. , vol.392 , pp. 67-71
    • Stengel, A.1    Goebel, M.2    Wang, L.3    Taché, Y.4    Sachs, G.5    Lambrecht, N.W.6
  • 174
    • 58149466993 scopus 로고    scopus 로고
    • Identification and characterization of nesfatin-1 immunoreactivity in endocrine cell types of the rat gastric oxyn-tic mucosa
    • Stengel, A., Goebel, M., Yakubov, I., Wang, L., Witcher, D., Coskun, T., Taché, Y., Sachs, G., and Lam-brecht, N. W. (2009a). Identification and characterization of nesfatin-1 immunoreactivity in endocrine cell types of the rat gastric oxyn-tic mucosa. Endocrinology 150, 232-238.
    • (2009) Endocrinology , vol.150 , pp. 232-238
    • Stengel, A.1    Goebel, M.2    Yakubov, I.3    Wang, L.4    Witcher, D.5    Coskun, T.6    Taché, Y.7    Sachs, G.8    Lam-brecht, N.W.9
  • 175
    • 70350266819 scopus 로고    scopus 로고
    • The RAPID method for blood processing yields new insight in plasma concentrations and molecular forms of circulating gut peptides
    • Stengel, A., Keire, D., Goebel, M., Evile-vitch, L., Wiggins, B., Taché, Y., and Reeve, J. R. Jr. (2009b). The RAPID method for blood processing yields new insight in plasma concentrations and molecular forms of circulating gut peptides. Endocrinology 150, 5113-5118.
    • (2009) Endocrinology , vol.150 , pp. 5113-5118
    • Stengel, A.1    Keire, D.2    Goebel, M.3    Evile-vitch, L.4    Wiggins, B.5    Taché, Y.6    Reeve Jr., J.R.7
  • 176
    • 79959324854 scopus 로고    scopus 로고
    • Central administration of pan-somatostatin agonist ODT8-SST prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats
    • Stengel, A., Goebel-Stengel, M., Wang, L., Luckey, A., Hu, E., Rivier, J., and Taché, Y. (2011a). Central administration of pan-somatostatin agonist ODT8-SST prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats. Neurogastroen-terol. Motil. 23, e294-e308.
    • (2011) Neurogastroen-terol. Motil. , vol.23
    • Stengel, A.1    Goebel-Stengel, M.2    Wang, L.3    Luckey, A.4    Hu, E.5    Rivier, J.6    Taché, Y.7
  • 178
    • 81755179399 scopus 로고    scopus 로고
    • Stress-related alterations of acyl and desacyl ghrelin circulating levels: mechanisms and functional implications
    • Stengel, A., Wang, L., and Taché, Y. (2011c). Stress-related alterations of acyl and desacyl ghrelin circulating levels: mechanisms and functional implications. Peptides 32, 2208-2217.
    • (2011) Peptides , vol.32 , pp. 2208-2217
    • Stengel, A.1    Wang, L.2    Taché, Y.3
  • 179
    • 79960024164 scopus 로고    scopus 로고
    • Ghre-lin: new insight to mechanisms and treatment of postoperative gastric ileus
    • Stengel, A., and Taché, Y. (2011). Ghre-lin: new insight to mechanisms and treatment of postoperative gastric ileus. Curr. Pharm. Des. 17, 1587-1593.
    • (2011) Curr. Pharm. Des. , vol.17 , pp. 1587-1593
    • Stengel, A.1    Taché, Y.2
  • 181
    • 0242580169 scopus 로고    scopus 로고
    • Deletion of ghrelin impairs neither growth nor appetite
    • Sun, Y., Ahmed, S., and Smith, R. G. (2003). Deletion of ghrelin impairs neither growth nor appetite. Mol. Cell. Biol. 23, 7973-7981.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 7973-7981
    • Sun, Y.1    Ahmed, S.2    Smith, R.G.3
  • 182
    • 1842480284 scopus 로고    scopus 로고
    • Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
    • Sun, Y., Wang, P., Zheng, H., and Smith, R. G. (2004). Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc. Natl. Acad. Sci. U.S.A. 101, 4679-4684.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 4679-4684
    • Sun, Y.1    Wang, P.2    Zheng, H.3    Smith, R.G.4
  • 185
    • 0033547818 scopus 로고    scopus 로고
    • Treatment with growth hormone enhances contractile reserve and intracellular calcium transients in myocytes from rats with postinfarction heart failure
    • Tajima, M., Weinberg, E. O., Bartunek, J., Jin, H., Yang, R., Paoni, N. F., and Lorell, B. H. (1999). Treatment with growth hormone enhances contractile reserve and intracellular calcium transients in myocytes from rats with postinfarction heart failure. Circulation 99, 127-134.
    • (1999) Circulation , vol.99 , pp. 127-134
    • Tajima, M.1    Weinberg, E.O.2    Bartunek, J.3    Jin, H.4    Yang, R.5    Paoni, N.F.6    Lorell, B.H.7
  • 186
    • 4644274876 scopus 로고    scopus 로고
    • Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats
    • Tang-Christensen, M., Vrang, N., Ort-mann, S., Bidlingmaier, M., Hor-vath, T. L., and Tschop, M. (2004). Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats. Endocrinology 145, 4645-4652.
    • (2004) Endocrinology , vol.145 , pp. 4645-4652
    • Tang-Christensen, M.1    Vrang, N.2    Ort-mann, S.3    Bidlingmaier, M.4    Hor-vath, T.L.5    Tschop, M.6
  • 188
    • 63449099349 scopus 로고    scopus 로고
    • Effects of ghrelin on interdigestive contractions of the rat gastrointestinal tract
    • Taniguchi, H., Ariga, H., Zheng, J., Lud-wig, K., and Takahashi, T. (2008b). Effects of ghrelin on interdigestive contractions of the rat gastrointestinal tract. World J. Gastroenterol. 14, 6299-6302.
    • (2008) World J. Gastroenterol. , vol.14 , pp. 6299-6302
    • Taniguchi, H.1    Ariga, H.2    Zheng, J.3    Lud-wig, K.4    Takahashi, T.5
  • 189
    • 25444433117 scopus 로고    scopus 로고
    • Central neuropeptide Y receptors are involved in 3rd ventricular ghrelin induced alteration of colonic transit time in conscious fed rats
    • doi:10.1186/1471-230X-5-5
    • Tebbe, J. J., Tebbe, C. G., Mronga, S., Ritter, M., and Schafer, M. K. (2005). Central neuropeptide Y receptors are involved in 3rd ventricular ghrelin induced alteration of colonic transit time in conscious fed rats. BMC Gastroenterol. 5, 5. doi:10.1186/1471-230X-5-5
    • (2005) BMC Gastroenterol , vol.5 , pp. 5
    • Tebbe, J.J.1    Tebbe, C.G.2    Mronga, S.3    Ritter, M.4    Schafer, M.K.5
  • 195
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop, M., Smiley, D. L., and Heiman, M. L. (2000). Ghrelin induces adiposity in rodents. Nature 407, 908-913.
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 199
    • 38149107496 scopus 로고    scopus 로고
    • Effect of ghrelin on gastric myoelec-tric activity and gastric emptying in rats
    • Tumer, C., Oflazoglu, H. D., Obay, B. D., Kelle, M., and Tasdemir, E. (2008). Effect of ghrelin on gastric myoelec-tric activity and gastric emptying in rats. Regul. Pept. 146, 26-32.
    • (2008) Regul. Pept. , vol.146 , pp. 26-32
    • Tumer, C.1    Oflazoglu, H.D.2    Obay, B.D.3    Kelle, M.4    Tasdemir, E.5
  • 201
    • 79958080521 scopus 로고    scopus 로고
    • Ghrelin in Type 2 diabetes mellitus and metabolic syndrome
    • Ukkola, O. (2011). Ghrelin in Type 2 diabetes mellitus and metabolic syndrome. Mol. Cell. Endocrinol. 340, 26-28.
    • (2011) Mol. Cell. Endocrinol. , vol.340 , pp. 26-28
    • Ukkola, O.1
  • 203
    • 67449110701 scopus 로고    scopus 로고
    • Cardiovascular effects of ghrelin antagonist in conscious rats
    • Vlasova, M. A., Jarvinen, K., and Herzig, K. H. (2009). Cardiovascular effects of ghrelin antagonist in conscious rats. Regul. Pept. 156, 72-76.
    • (2009) Regul. Pept. , vol.156 , pp. 72-76
    • Vlasova, M.A.1    Jarvinen, K.2    Herzig, K.H.3
  • 205
    • 0037204861 scopus 로고    scopus 로고
    • Peripheral ghrelin selectively increases Fos expression in neuropeptide Y - synthesizing neurons in mouse hypothalamic arcuate nucleus
    • Wang, L., Saint-Pierre, D. H., and Taché, Y. (2002). Peripheral ghrelin selectively increases Fos expression in neuropeptide Y - synthesizing neurons in mouse hypothalamic arcuate nucleus. Neurosci. Lett. 325, 47-51.
    • (2002) Neurosci. Lett. , vol.325 , pp. 47-51
    • Wang, L.1    Saint-Pierre, D.H.2    Taché, Y.3
  • 207
    • 0032744366 scopus 로고    scopus 로고
    • Co-localization of growth hormone secretagogue receptor and NPY mRNA in the arcuate nucleus of the rat
    • Willesen, M. G., Kristensen, P., and Romer, J. (1999). Co-localization of growth hormone secretagogue receptor and NPY mRNA in the arcuate nucleus of the rat. Neuroen-docrinology 70, 306-316.
    • (1999) Neuroen-docrinology , vol.70 , pp. 306-316
    • Willesen, M.G.1    Kristensen, P.2    Romer, J.3
  • 210
    • 34247640178 scopus 로고    scopus 로고
    • Ghre-lin down-regulates proinflamma-tory cytokines in sepsis through activation of the vagus nerve
    • Wu, R., Dong, W., Cui, X., Zhou, M., Simms, H. H., Ravikumar, T. S., and Wang, P. (2007a). Ghre-lin down-regulates proinflamma-tory cytokines in sepsis through activation of the vagus nerve. Ann. Surg. 245, 480-486.
    • (2007) Ann. Surg. , vol.245 , pp. 480-486
    • Wu, R.1    Dong, W.2    Cui, X.3    Zhou, M.4    Simms, H.H.5    Ravikumar, T.S.6    Wang, P.7
  • 212
    • 44349190224 scopus 로고    scopus 로고
    • Orexigenic hormone ghrelin attenuates local and remote organ injury after intestinal ischemia-reperfusion
    • doi:10.1371/journal.pone.0002026
    • Wu, R., Dong, W., Ji, Y., Zhou, M., Marini, C. P., Ravikumar, T. S., and Wang, P. (2008). Orexigenic hormone ghrelin attenuates local and remote organ injury after intestinal ischemia-reperfusion. PLoS ONE 3, e2026. doi:10.1371/journal.pone.0002026
    • (2008) PLoS ONE , vol.3
    • Wu, R.1    Dong, W.2    Ji, Y.3    Zhou, M.4    Marini, C.P.5    Ravikumar, T.S.6    Wang, P.7
  • 213
    • 26444572289 scopus 로고    scopus 로고
    • Ghrelin improves tissue per-fusion in severe sepsis via downreg-ulation of endothelin-1
    • Wu, R., Dong, W., Zhou, M., Cui, X., Hank Simms, H., and Wang, P. (2005). Ghrelin improves tissue per-fusion in severe sepsis via downreg-ulation of endothelin-1. Cardiovasc. Res. 68, 318-326.
    • (2005) Cardiovasc. Res. , vol.68 , pp. 318-326
    • Wu, R.1    Dong, W.2    Zhou, M.3    Cui, X.4    Hank Simms, H.5    Wang, P.6
  • 214
    • 3242725318 scopus 로고    scopus 로고
    • Ghrelin clearance is reduced at the late stage of polymicrobial sepsis
    • Wu, R., Zhou, M., Cui, X., Simms, H. H., and Wang, P. (2003). Ghrelin clearance is reduced at the late stage of polymicrobial sepsis. Int. J. Mol. Med. 12, 777-781.
    • (2003) Int. J. Mol. Med. , vol.12 , pp. 777-781
    • Wu, R.1    Zhou, M.2    Cui, X.3    Simms, H.H.4    Wang, P.5
  • 215
    • 5644271873 scopus 로고    scopus 로고
    • Effects of ghrelin on the proliferation and secretion of splenic T lymphocytes in mice
    • Xia, Q., Pang, W., Pan, H., Zheng, Y., Kang, J. S., and Zhu, S. G. (2004). Effects of ghrelin on the proliferation and secretion of splenic T lymphocytes in mice. Regul. Pept. 122, 173-178.
    • (2004) Regul. Pept. , vol.122 , pp. 173-178
    • Xia, Q.1    Pang, W.2    Pan, H.3    Zheng, Y.4    Kang, J.S.5    Zhu, S.G.6
  • 217
    • 38849090670 scopus 로고    scopus 로고
    • Identification of the acyl-transferase that octanoylates ghre-lin, an appetite-stimulating peptide hormone
    • Yang, J., Brown, M. S., Liang, G., Grishin, N. V., and Goldstein, J. L. (2008). Identification of the acyl-transferase that octanoylates ghre-lin, an appetite-stimulating peptide hormone. Cell 132, 387-396.
    • (2008) Cell , vol.132 , pp. 387-396
    • Yang, J.1    Brown, M.S.2    Liang, G.3    Grishin, N.V.4    Goldstein, J.L.5
  • 218
    • 44449134342 scopus 로고    scopus 로고
    • Endotoxin increases plasma leptin and ghrelin levels in dogs
    • Yilmaz, Z., Ilcol, Y. O., and Ulus, I. H. (2008). Endotoxin increases plasma leptin and ghrelin levels in dogs. Crit. Care Med. 36, 828-833.
    • (2008) Crit. Care Med. , vol.36 , pp. 828-833
    • Yilmaz, Z.1    Ilcol, Y.O.2    Ulus, I.H.3
  • 219
    • 33745698827 scopus 로고    scopus 로고
    • Inhibitory effects of gastric electrical stimulation on ghrelin-induced excitatory effects on gastric motility and food intake in dogs
    • Yin, J., and Chen, J. (2006). Inhibitory effects of gastric electrical stimulation on ghrelin-induced excitatory effects on gastric motility and food intake in dogs. Scand. J. Gastroen-terol. 41, 903-909.
    • (2006) Scand. J. Gastroen-terol. , vol.41 , pp. 903-909
    • Yin, J.1    Chen, J.2
  • 220
    • 68949167649 scopus 로고    scopus 로고
    • A novel peptide ghrelin inhibits neural remodeling after myocardial infarction in rats
    • Yuan, M. J., Huang, C. X., Tang, Y. H., Wang, X., Huang, H., Chen, Y. J., and Wang, T. (2009). A novel peptide ghrelin inhibits neural remodeling after myocardial infarction in rats. Eur. J. Pharmacol. 618, 52-57.
    • (2009) Eur. J. Pharmacol. , vol.618 , pp. 52-57
    • Yuan, M.J.1    Huang, C.X.2    Tang, Y.H.3    Wang, X.4    Huang, H.5    Chen, Y.J.6    Wang, T.7
  • 222
    • 27744600963 scopus 로고    scopus 로고
    • Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake
    • Zhang, J. V., Ren, P. G., Avsian-Kretchmer, O., Luo, C. W., Rauch, R., Klein, C., and Hsueh, A. J. (2005). Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science 310, 996-999.
    • (2005) Science , vol.310 , pp. 996-999
    • Zhang, J.V.1    Ren, P.G.2    Avsian-Kretchmer, O.3    Luo, C.W.4    Rauch, R.5    Klein, C.6    Hsueh, A.J.7
  • 223
    • 50449085374 scopus 로고    scopus 로고
    • Effect of des-acyl ghre-lin on adiposity and glucose metabolism
    • Zhang, W., Chai, B., Li, J. Y., Wang, H., and Mulholland, M. W. (2008). Effect of des-acyl ghre-lin on adiposity and glucose metabolism. Endocrinology 149, 4710-4716.
    • (2008) Endocrinology , vol.149 , pp. 4710-4716
    • Zhang, W.1    Chai, B.2    Li, J.Y.3    Wang, H.4    Mulholland, M.W.5
  • 224
    • 39149138127 scopus 로고    scopus 로고
    • Characterization of obestatin- and ghrelin-producing cells in the gastrointestinal tract and pancreas of rats: an immunohistochemical and electron-microscopic study
    • Zhao, C. M., Furnes, M. W., Stenstrom, B., Kulseng, B., and Chen, D. (2008). Characterization of obestatin- and ghrelin-producing cells in the gastrointestinal tract and pancreas of rats: an immunohistochemical and electron-microscopic study. Cell Tissue Res. 331, 575-587.
    • (2008) Cell Tissue Res , vol.331 , pp. 575-587
    • Zhao, C.M.1    Furnes, M.W.2    Stenstrom, B.3    Kulseng, B.4    Chen, D.5
  • 226
    • 58149218357 scopus 로고    scopus 로고
    • Ghrelin regulates gastric phase III-like contractions in freely moving conscious mice
    • Zheng, J., Ariga, H., Taniguchi, H., Lud-wig, K., and Takahashi, T. (2009a). Ghrelin regulates gastric phase III-like contractions in freely moving conscious mice. Neurogastroenterol. Motil. 21, 78-84.
    • (2009) Neurogastroenterol. Motil. , vol.21 , pp. 78-84
    • Zheng, J.1    Ariga, H.2    Taniguchi, H.3    Lud-wig, K.4    Takahashi, T.5
  • 228
    • 70349925383 scopus 로고    scopus 로고
    • Ghre-lin inhibits the development of acute pancreatitis and nuclear factor kap-paB activation in pancreas and liver
    • Zhou, X., and Xue, C. (2009). Ghre-lin inhibits the development of acute pancreatitis and nuclear factor kap-paB activation in pancreas and liver. Pancreas 38, 752-757.
    • (2009) Pancreas , vol.38 , pp. 752-757
    • Zhou, X.1    Xue, C.2
  • 229
    • 0043030280 scopus 로고    scopus 로고
    • Minireview: from anorexia to obesity - the yin and yang of body weight control
    • Zigman, J. M., and Elmquist, J. K. (2003). Minireview: from anorexia to obesity - the yin and yang of body weight control. Endocrinology 144, 3749-3756.
    • (2003) Endocrinology , vol.144 , pp. 3749-3756
    • Zigman, J.M.1    Elmquist, J.K.2
  • 230
    • 29044434688 scopus 로고    scopus 로고
    • Expression of ghrelin receptor mRNA in the rat and the mouse brain
    • Zigman, J. M., Jones, J. E., Lee, C. E., Saper, C. B., and Elmquist, J. K. (2006). Expression of ghrelin receptor mRNA in the rat and the mouse brain. J. Comp. Neurol. 494, 528-548.
    • (2006) J. Comp. Neurol. , vol.494 , pp. 528-548
    • Zigman, J.M.1    Jones, J.E.2    Lee, C.E.3    Saper, C.B.4    Elmquist, J.K.5


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