Ghrelin stimulates corticotropin-releasing factor and vasopressin gene expression in rat hypothalamic 4B cells

Stress

Volumn 14, Issue 5, 2011, Pages 520-529

  Kageyama, Kazunori ^a   Kumata, Yukiko ^a   Akimoto, Kanako ^a   Takayasu, Shinobu ^a   Tamasawa, Naoki ^a   Suda, Toshihiro ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

Corticotropin releasing factor; ghrelin; hypothalamus; stress; vasopressin

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; GHRELIN; GHRELIN RECEPTOR; GLUCOCORTICOID; MESSENGER RNA; PHOSPHOLIPASE C; PROTEIN KINASE; VASOPRESSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOTHALAMUS; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ARGININE VASOPRESSIN; CELLS, CULTURED; CORTICOTROPIN-RELEASING HORMONE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC GMP; GENE EXPRESSION; GHRELIN; HYPOTHALAMUS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PROMOTER REGIONS, GENETIC; PROTEIN KINASE INHIBITORS; RATS; RNA, MESSENGER; TYPE C PHOSPHOLIPASES;

EID: 80051740293     PISSN: 10253890     EISSN: 16078888     Source Type: Journal    
DOI: 10.3109/10253890.2011.558605     Document Type: Article

References (33)

1. Arvat E, Maccario M, Di Vito L, Broglio F, Benso A, Gottero C, Papotti M, Muccioli G, Dieguez C, Casanueva F F, Deghenghi R, Camanni F, Ghigo E. 2001. Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: Comparison and interactions with hexarelin, a nonnatural peptidyl GH S, and GH-releasing hormone. J Clin Endocrinol Metab 86:1169-1174. (Pubitemid 32323000)
2. Asakawa A, Inui A, Kaga T, Yuzuriha H, Nagata T, Fujimiya M, Katsuura G, Makino S, Fujino MA, Kasuga M. 2001. A role of ghrelin in neuroendocrine and behavioral responses to stress in mice. Neuroendocrinology 74:143-147. (Pubitemid 32786213)
3. Bowers C Y. 1993. GH releasing peptides-structure and kinetics. J Pediatr Endocrinol 6:21-31.
4. Burbach JP, Luckman SM, Murphy D, Gainer H. 2001. Gene regulation in the magnocellular hypothalamo-neurohypophysial system. Physiol Rev 81:1197-1267. (Pubitemid 32606669)
5. Herman JP, Prewitt CM, Cullinan W E. 1996. Neuronal circuit regulation of the hypothalamo-pituitary-adrenocortical stress axis. Crit Rev Neurobiol 10:371-394. (Pubitemid 27036104)
6. Hirotani C, Oki Y, Ukai K, Okuno T, Kurasaki S, Ohyama T, Doi N, Sasaki K, Ase K. 2005. ACTH releasing activity of KP-102 (GHRP-2) in rats is mediated mainly by release of CR F. Naunyn Schmiedebergs Arch Pharmacol 371:54-60. (Pubitemid 40379388)
7. Horvath TL, Diano S, Sotonyi P, Heiman M, Tschöp M. 2001. Minireview: Ghrelin and the regulation of energy balance-a hypothalamic perspective. Endocrinology 142:4163-4169. (Pubitemid 32907040)
8. Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, Hamelin M, Hreniuk DL, Palyha OC, Anderson J, Paress PS, Diaz C, Chou M, Liu KK, McKee KK, Pong SS, Chaung LY, Elbrecht A, Dashkevicz M, Heavens R, Rigby M, Sirinathsinghji DJ, Dean DC, Melillo DG, Patchett AA, Nargund R, Griffin PR, DeMartino JA, Gupta SK, Schaeffer JM, Smith RG, Van der Ploeg L H. 1996. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 273:974-977. (Pubitemid 26275178)
9. Itoi K, Horiba N, Tozawa F, Sakai Y, Sakai K, Abe K, Demura H, Suda T. 1996. Major role of 30 ,50-cyclic adenosine monophosphate-dependent protein kinase A pathway in corticotropin-releasing factor gene expression in the rat hypothalamus in vivo. Endocrinology 137:2389-2396.
10. Kageyama K, Hanada K, Iwasaki Y, Sakihara S, Nigawara T, Kasckow J, Suda T. 2007. Pituitary adenylate cyclase-activating polypeptide stimulates corticotropin-releasing factor, vasopres-sin, and interleukin-6 gene transcription in hypothalamic 4B cells. J Endocrinol 195:199-211. (Pubitemid 350143101)
11. Kageyama K, Hanada K, Takayasu S, Iwasaki Y, Sakihara S, Nigawara T, Kasckow J, Suda T. 2008. Involvement of regulatory elements on corticotropin-releasing factor gene promoter in hypothalamic 4B cells. J Endocrinol Invest 31: 1079-1085.
12. Kamegai J, Tamura H, Ishii S, Sugihara H, Wakabayashi I. 2001. Thyroid hormones regulate pituitary growth hormone secreta-gogue receptor gene expression. J Neuroendocrinol 13: 275-278. (Pubitemid 32170992)
13. Kasckow J, Mulchahey JJ, Aguilera G, Pisarska M, Nikodemova M, Chen HC, Herman JP, Murphy EK, Liu Y, Rizvi TA, Dautzenberg FM, Sheriff S. 2003. Corticotropin-releasing hormone (CRH) expression and protein kinase A mediated CRH receptor signalling in an immortalized hypothalamic cell line. J Neuroendocrinol 15:521-529. (Pubitemid 36582468)
14. Kawashima S, Sakihara S, Kageyama K, Nigawara T, Suda T. 2008. Corticotropin-releasing factor (CRF) is involved in the acute anorexic effect of a-melanocyte-stimulating hormone: A study using CRF-deficient mice. Peptides 29:2169-2174. (Pubitemid 50315792)
15. Kineman RD, Kamegai J, Frohman L A. 1999. Growth hormone (GH)-releasing hormone (GHRH) and the GH secretagogue (GHS), L692,585, differentially modulate rat pituitary GHS receptor and GHRH receptor messenger ribonucleic acid levels. Endocrinology 140:3581-3586. (Pubitemid 30645412)
16. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. 1999. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402:656-660. (Pubitemid 129516334)
17. Korbonits M, Kaltsas G, Perry LA, Putignano P, Grossman AB, Besser GM, Trainer P J. 1999a. The growth hormone secretagogue hexarelin stimulates the hypothalamo-pituitary-adrenal axis via arginine vasopressin. J Clin Endocrinol Metab 84:2489-2495.
18. Korbonits M, Little JA, Forsling ML, Tringali G, Costa A, Navarra P, Trainer PJ, Grossman A B. 1999b. The effect of growth hormone secretagogues and neuropeptide Y on hypothalamic hormone release from acute rat hypothalamic explants. J Neuroendocrinol 11:521-528. (Pubitemid 29312845)
19. Liu Y, Kamitakahara A, Kim AJ, Aguilera G. 2008. Cyclic adenosine 30,50-monophosphate responsive element binding protein phosphorylation is required but not sufficient for activation of corticotropin-releasing hormone transcription. Endocrinology 149:3512-3520. (Pubitemid 351919576)
20. Liu Y, Coello AG, Grinevich V, Aguilera G. 2010. Involvement of transducer of regulated cAMP response element-binding protein activity on corticotropin releasing hormone transcription. Endocrinology 151:1109-1118.
21. Malagón MM, Luque RM, Ruiz-Guerrero E, Rodríguez-Pacheco F, García-Navarro S, Casanueva FF, Gracia-Navarro F, Castaño J P. 2003. Intracellular signaling mechanisms mediating ghrelin-stimulated growth hormone release in somatotropes. Endocrinology 144:5372-5380. (Pubitemid 37476066)
22. Mercer JG, Lawrence CB, Moar KM, Atkinson T, Barrett P. 1997. Short-day weight loss and effect of food deprivation on hypothalamic NPY and CRF mRNA in Djungarian hamsters. Am J Physiol 273:R768-R776.
23. Mozid AM, Tringali G, Forsling ML, Hendricks MS, Ajodha S, Edwards R, Navarra P, Grossman AB, Korbonits M. 2003. Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin. Horm Metab Res 35:455-459. (Pubitemid 37204560)
24. Palkovits M, Baffi JS, Pacak K. 1999. The role of ascending neuronal pathways in stress-induced release of noradrenaline in the hypothalamic paraventricular nucleus of rats. J Neuroendo-crinol 11:529-539. (Pubitemid 29312846)
25. Pérez-Fontán M, Cordido F, Rodríguez-Carmona A, Peteiro J, García-Naveiro R, García-Buela J. 2004. Plasma ghrelin levels in patients undergoing haemodialysis and peritoneal dialysis. Nephrol Dial Transplant 19:2095-2100. (Pubitemid 39139643)
26. Rodríguez-Pacheco F, Luque RM, García-Navarro S, Gracia-Navarro F, Castaño JP, Malagón M M. 2005. Ghrelin induces growth hormone (GH) secretion via nitric oxide (NO)/cGMP signaling. Ann NY Acad Sci 1040:452-453. (Pubitemid 40979838)
27. Seasholtz AF, Thompson RC, Douglass J O. 1988. Identification of a cyclic adenosine monophosphate-responsive element in the rat corticotropin-releasing hormone gene. Mol Endocrinol 2: 1311-1319. (Pubitemid 19005944)
28. Shiiya T, Nakazato M, Mizuta M, Date Y, Mondal MS, Tanaka M, Nozoe S, Hosoda H, Kangawa K, Matsukura S. 2002. Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab 87:240-244. (Pubitemid 34084697)
29. Spengler D, Rupprecht R, Van LP, Holsboer F. 1992. Identification and characterization of a 30,50-cyclic adenosine monophosphate-responsive element in the human corticotropin-releasing hormone gene promoter. Mol Endocrinol 6:1931-1941.
30. Vandesande F, Dierickx K, De Mey J. 1997. The origin of the vasopressinergic and oxytocinergic fibres of the external region of the median eminence of the rat hypophysis. Cell Tissue Res 180:443-452.
31. Whitnall M H. 1993. Regulation of the hypothalamic corticotropin- releasing hormone neurosecretory system. Prog Neurobiol 40: 573-629. (Pubitemid 23091955)
32. Wren AM, Small CJ, Fribbens CV, Neary NM, Ward HL, Seal LJ, Ghatei MA, Bloom S R. 2002. The hypothalamic mechanisms of the hypophysiotropic action of ghrelin. Neuroendocrinology 76: 316-324. (Pubitemid 35404284)
33. Yoshida M, Iwasaki Y, Asai M, Takayasu S, Taguchi T, Itoi K, Hashimoto K, Oiso Y. 2006. Identification of a functional AP1 element in the rat vasopressin gene promoter. Endocrinology 147:2850-2863. (Pubitemid 43764621)