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Volumn 132, Issue 3, 2008, Pages 387-396

Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone

Author keywords

CHEMBIO; HUMDISEASE; PROTEINS

Indexed keywords

ACYLTRANSFERASE; GHRELIN; GHRELIN O ACYLTRANSFERASE; UNCLASSIFIED DRUG;

EID: 38849090670     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2008.01.017     Document Type: Article
Times cited : (1008)

References (33)
  • 2
    • 0026550830 scopus 로고
    • Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines
    • Asfari M., Janjic D., Meda P., Li G., Halban P.A., and Wollheim C.B. Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 130 (1992) 167-178
    • (1992) Endocrinology , vol.130 , pp. 167-178
    • Asfari, M.1    Janjic, D.2    Meda, P.3    Li, G.4    Halban, P.A.5    Wollheim, C.B.6
  • 3
    • 0029022642 scopus 로고
    • Chemical analysis of acylation sites and species
    • Bizzozero O.A. Chemical analysis of acylation sites and species. Methods Enzymol. 250 (1995) 361-379
    • (1995) Methods Enzymol. , vol.250 , pp. 361-379
    • Bizzozero, O.A.1
  • 5
    • 1842853184 scopus 로고    scopus 로고
    • Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates
    • Chen M.-H., Li Y.-J., Kawakami T., Xu S.-M., and Chuang P.T. Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates. Genes Dev. 18 (2004) 641-659
    • (2004) Genes Dev. , vol.18 , pp. 641-659
    • Chen, M.-H.1    Li, Y.-J.2    Kawakami, T.3    Xu, S.-M.4    Chuang, P.T.5
  • 6
    • 33746739498 scopus 로고    scopus 로고
    • Ghrelin and short- and long-term regulation of appetite and body weight
    • Cummings D.E. Ghrelin and short- and long-term regulation of appetite and body weight. Physio. Behavior 89 (2006) 71-84
    • (2006) Physio. Behavior , vol.89 , pp. 71-84
    • Cummings, D.E.1
  • 7
    • 0035433977 scopus 로고    scopus 로고
    • A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    • Cummings D.E., Purnell J.Q., Frayo R.S., Schmidova K., Wisse B.E., and Weigle D.S. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 50 (2001) 1714-1719
    • (2001) Diabetes , vol.50 , pp. 1714-1719
    • Cummings, D.E.1    Purnell, J.Q.2    Frayo, R.S.3    Schmidova, K.4    Wisse, B.E.5    Weigle, D.S.6
  • 8
    • 0033679897 scopus 로고    scopus 로고
    • Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans
    • Date Y., Kojima M., Hosoda H., Sawaguchi A., Mondal M.S., Suganuma T., Matsukura S., Kangawa K., and Nakazato M. Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 141 (2000) 4255-4261
    • (2000) Endocrinology , vol.141 , pp. 4255-4261
    • Date, Y.1    Kojima, M.2    Hosoda, H.3    Sawaguchi, A.4    Mondal, M.S.5    Suganuma, T.6    Matsukura, S.7    Kangawa, K.8    Nakazato, M.9
  • 10
    • 0035830840 scopus 로고    scopus 로고
    • Unsaturated fatty acids down-regulate SREBP isoforms 1a and 1c by two mechanisms in HEK-293 cells
    • Hannah V.C., Ou J., Luong A., Goldstein J.L., and Brown M.S. Unsaturated fatty acids down-regulate SREBP isoforms 1a and 1c by two mechanisms in HEK-293 cells. J. Biol. Chem. 276 (2001) 4365-4372
    • (2001) J. Biol. Chem. , vol.276 , pp. 4365-4372
    • Hannah, V.C.1    Ou, J.2    Luong, A.3    Goldstein, J.L.4    Brown, M.S.5
  • 11
    • 0034161499 scopus 로고    scopus 로고
    • A superfamily of membrane-bound O-acyltransferases with implications for Wnt signaling
    • Hofmann K. A superfamily of membrane-bound O-acyltransferases with implications for Wnt signaling. Trends Biochem. Sci. 25 (2000) 111-112
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 111-112
    • Hofmann, K.1
  • 12
    • 0030450052 scopus 로고    scopus 로고
    • The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing
    • Kadowaki T., Wilder E., Klingensmith J., Zachary K., and Perrimon N. The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes Dev. 10 (1996) 3116-3128
    • (1996) Genes Dev. , vol.10 , pp. 3116-3128
    • Kadowaki, T.1    Wilder, E.2    Klingensmith, J.3    Zachary, K.4    Perrimon, N.5
  • 13
    • 3042746882 scopus 로고    scopus 로고
    • Structural determination and histochemical localization of ghrelin in the red-eared slider turtle, Trachemys scripta elegans
    • Kaiya H., Sakata I., Kojima M., Hosoda H., Sakai T., and Kangawa K. Structural determination and histochemical localization of ghrelin in the red-eared slider turtle, Trachemys scripta elegans. Gen. Comp. Endocrinol. 138 (2004) 50-57
    • (2004) Gen. Comp. Endocrinol. , vol.138 , pp. 50-57
    • Kaiya, H.1    Sakata, I.2    Kojima, M.3    Hosoda, H.4    Sakai, T.5    Kangawa, K.6
  • 14
    • 0035513696 scopus 로고    scopus 로고
    • Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and Agouti-related protein mRNA levels and body weight in rats
    • Kamegai J., Tamura H., Shimizu T., Ishli S., Sugihara H., and Wakabayashi I. Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and Agouti-related protein mRNA levels and body weight in rats. Diabetes 50 (2001) 2438-2443
    • (2001) Diabetes , vol.50 , pp. 2438-2443
    • Kamegai, J.1    Tamura, H.2    Shimizu, T.3    Ishli, S.4    Sugihara, H.5    Wakabayashi, I.6
  • 15
    • 0031898207 scopus 로고    scopus 로고
    • Fusion PCR, a one-step variant of the "Megaprimer" method of mutagenesis
    • Karreman C. Fusion PCR, a one-step variant of the "Megaprimer" method of mutagenesis. Biotechniques 24 (1998) 736-742
    • (1998) Biotechniques , vol.24 , pp. 736-742
    • Karreman, C.1
  • 16
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402 (1999) 656-660
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 17
    • 15544385058 scopus 로고    scopus 로고
    • Ghrelin: Structure and function
    • Kojima M., and Kangawa K. Ghrelin: Structure and function. Physiol. Rev. 85 (2005) 495-522
    • (2005) Physiol. Rev. , vol.85 , pp. 495-522
    • Kojima, M.1    Kangawa, K.2
  • 18
    • 0025281303 scopus 로고
    • Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms
    • Miyazaki J., Araki K., Yamato E., Ikegami H., Asano T., Shibasaki Y., Oka Y., and Yamamura K. Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. Endocrinology 127 (1990) 126-132
    • (1990) Endocrinology , vol.127 , pp. 126-132
    • Miyazaki, J.1    Araki, K.2    Yamato, E.3    Ikegami, H.4    Asano, T.5    Shibasaki, Y.6    Oka, Y.7    Yamamura, K.8
  • 21
    • 0034604350 scopus 로고    scopus 로고
    • Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes
    • Nohturfft A., Yabe D., Goldstein J.L., Brown M.S., and Espenshade P.J. Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes. Cell 102 (2000) 315-323
    • (2000) Cell , vol.102 , pp. 315-323
    • Nohturfft, A.1    Yabe, D.2    Goldstein, J.L.3    Brown, M.S.4    Espenshade, P.J.5
  • 23
    • 3843089529 scopus 로고    scopus 로고
    • Gut hormones and the control of appetite
    • Small C.J., and Bloom S.R. Gut hormones and the control of appetite. Trends Endocrinol. Metab. 15 (2004) 259-263
    • (2004) Trends Endocrinol. Metab. , vol.15 , pp. 259-263
    • Small, C.J.1    Bloom, S.R.2
  • 25
    • 0030623948 scopus 로고    scopus 로고
    • SEALS: A system for easy analysis of lots of sequences
    • Walker D., and Koonin E. SEALS: A system for easy analysis of lots of sequences. Intel. Sys. Mol. Biol. 5 (1997) 333-339
    • (1997) Intel. Sys. Mol. Biol. , vol.5 , pp. 333-339
    • Walker, D.1    Koonin, E.2
  • 30
    • 33846024377 scopus 로고    scopus 로고
    • On the processing of proghrelin to ghrelin
    • Zhu X., Cao Y., Voodg K., and Steiner D.F. On the processing of proghrelin to ghrelin. J. Biol. Chem. 281 (2006) 38867-38870
    • (2006) J. Biol. Chem. , vol.281 , pp. 38867-38870
    • Zhu, X.1    Cao, Y.2    Voodg, K.3    Steiner, D.F.4
  • 31
    • 33748336260 scopus 로고    scopus 로고
    • In search of an effective obesity treatment: A shot in the dark or a shot in the arm?
    • Zigman J.M., and Elmquist J.K. In search of an effective obesity treatment: A shot in the dark or a shot in the arm?. Proc. Natl. Acad. Sci. USA 103 (2006) 12961-12962
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 12961-12962
    • Zigman, J.M.1    Elmquist, J.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.