Anorexigenic and electrophysiological actions of novel ghrelin receptor (GHS-R1A) antagonists in rats

European Journal of Pharmacology

Volumn 612, Issue 1-3, 2009, Pages 167-173

  Salomé, Nicolas ^a   Haage, David ^a,b   Perrissoud, Daniel ^c   Moulin, Aline ^d   Demange, Luc ^d   Egecioglu, Emil ^a   Fehrentz, Jean Alain ^d   Martinez, Jean ^d   Dickson, Suzanne L ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UMEÅ UNIVERSITY   (Sweden)

^c Aeterna Zentaris GmbH   (Germany)

^d CNRS   (France)

Author keywords

Arcuate nucleus; Feeding; Food intake; Growth hormone secretagogue; Hypothalamus; Neuropeptide Y

Indexed keywords

ANOREXIGENIC AGENT; GHRELIN; GHRELIN RECEPTOR; GHRELIN RECEPTOR ANTAGONIST; JMV 2810; JMV 2959; JMV 3002; N [1 [4 (2,4 DIMETHOXYBENZYL) 5 PHENETHYL 4H 1,2,4 TRIAZOL 3 YL] 2 (1H INDOL 3 YL)ETHYL]PICOLINAMIDE; N [1 [4 (4 METHOXYBENZYL) 5 PHENETHYL 4H 1,2,4 TRIAZOL 3 YL] 2 (1H INDOL 3 YL)ETHYL] 2 AMINOACETAMIDE; N [1 [5 [3 (1H INDOL 3 YL)PROPYL] 4 BENZYL 4H 1,2,4 TRIAZOL 3 YL] 2 (1H INDOL 3 YL)ETHYL] 2 AMINO 2 METHYLPROPANAMIDE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APPETITE DISORDER; ARCUATE NUCLEUS; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; FOOD INTAKE; LIGAND BINDING; LIPID STORAGE; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT;

ANIMALS; ARCUATE NUCLEUS; CHO CELLS; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; ELECTROPHYSIOLOGICAL PHENOMENA; ENERGY METABOLISM; FASTING; GHRELIN; HUMANS; INHIBITORY CONCENTRATION 50; LIGANDS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GHRELIN; TEMPERATURE; TIME FACTORS;

EID: 65549152532     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.03.066     Document Type: Article

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