Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 37, 2005, Pages 13135-13140

  Iwata, Atsushi ^a   Christianson, John C ^a   Bucci, Mirella ^a   Ellerby, Lisa M ^b   Nukina, Nobuyuki ^c   Forno, Lysia S ^d   Kopito, Ron R ^a  

^a STANFORD UNIVERSITY   (United States)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^d VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

Autophagy; Huntingtin; Huntington's disease

Indexed keywords

ATAXIN 1; HUNTINGTIN; POLYGLUTAMINE;

ARTICLE; AUTOPHAGY; CELL NUCLEUS; CELL NUCLEUS INCLUSION BODY; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; PRIORITY JOURNAL; PROTEIN AGGREGATION; SPINOCEREBELLAR DEGENERATION;

AUTOPHAGY; CELL LINE; CELL NUCLEUS; CYTOPLASM; HUMANS; HUNTINGTON DISEASE; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDES; PROTEIN TRANSPORT; PROTEINS; SPINOCEREBELLAR ATAXIAS; TRANSFECTION;

EID: 24944482408     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0505801102     Document Type: Article

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