Killing cells by targeting mitosis

Cell Death and Differentiation

Volumn 19, Issue 3, 2012, Pages 369-377

  Manchado, E ^a   Guillamot, M ^a   Malumbres, M ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

Author keywords

anaphase promoting complex Cdc20; apoptosis; cancer therapy; mitosis; mitotic cell death; mitotic kinases

Indexed keywords

4 [[9 CHLORO 7 (2,6 DIFLUOROPHENYL) 5H PYRIMIDO[5,4 D][2]BENZAZEPIN 2 YL]AMINO]BENZOIC ACID; ALISERTIB; ANAPHASE PROMOTING COMPLEX; ANTIMITOTIC AGENT; ARRY 520; AURORA KINASE; AZD 4877; BARASERTIB; CYCLIN DEPENDENT KINASE 1; DOCETAXEL; GSK 1070916 A; GSK 461364; GSK 923295 A; ISPINESIB; KINESIN; MPS 1 IN 1; NAVELBINE; NMS 1286937; NMS P 715; P 276 00; PACLITAXEL; POLO LIKE KINASE; PROTEIN SERINE THREONINE KINASE; RIGOSERTIB; TAXANE DERIVATIVE; TERAMEPROCOL; TKM 080301; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINBLASTINE; VINCA ALKALOID; VINCRISTINE; VINDESINE; VINFLUNINE; VOLASERTIB;

ANEUPLOIDY; APOPTOSIS; BONE MARROW SUPPRESSION; CANCER CELL; CANCER THERAPY; CELL CYCLE ARREST; CELL CYCLE CHECKPOINT; CELL CYCLE REGULATION; CELL DEATH; CELL KILLING; CELL PROLIFERATION; CHROMOSOMAL INSTABILITY; DRUG TARGETING; ENZYME INHIBITION; GENOMIC INSTABILITY; HUMAN; METAPHASE; MICROTUBULE ASSEMBLY; MITOSIS; MITOSIS INHIBITION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMALS; CDC2 PROTEIN KINASE; CHROMOSOMAL INSTABILITY; HUMANS; MITOSIS; MUTATION; NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; TUBULIN MODULATORS;

EID: 84857040864     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.197     Document Type: Review

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