-
1
-
-
0025885070
-
Isolation of the human Cdk2 gene that encodes the cyclin A- and adenovirus EiA-associated p33 kinase
-
Tsai, L.-H., Harlow, E. & Meyerson, M. Isolation of the human Cdk2 gene that encodes the cyclin A- and adenovirus EiA-associated p33 kinase. Nature 353, 174-177 (1991).
-
(1991)
Nature
, vol.353
, pp. 174-177
-
-
Tsai, L.-H.1
Harlow, E.2
Meyerson, M.3
-
2
-
-
0025894942
-
A new human p34 protein kinase, Cdk2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Egl
-
Elledge, S.J. & Spottswood, R. A new human p34 protein kinase, Cdk2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Egl. EMBO J. 10, 2653-2659 (1991).
-
(1991)
EMBO J.
, vol.10
, pp. 2653-2659
-
-
Elledge, S.J.1
Spottswood, R.2
-
3
-
-
0029849620
-
Cancer cell cycles
-
Sherr, C.J. Cancer cell cycles. Science 274, 1672-1677 (1996).
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
4
-
-
0031951182
-
Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
-
Lundberg, A.S. & Weinberg, R.A. Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol. Cell. Biol. 18, 753-761 (1998).
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 753-761
-
-
Lundberg, A.S.1
Weinberg, R.A.2
-
5
-
-
0033783177
-
Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators
-
Morris, L., Allen, K.E. & La Thangue, N.B. Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators, Nat. Cell. Biol. 2, 232-239 (2000).
-
(2000)
Nat. Cell. Biol.
, vol.2
, pp. 232-239
-
-
Morris, L.1
Allen, K.E.2
La Thangue, N.B.3
-
6
-
-
0035911969
-
Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication
-
Furstenthal, L., Kaiser, B.K., Swanson, C. & Jackson, P.K. Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication. J. Cell Biol. 152, 1267-1278 (2001).
-
(2001)
J. Cell Biol.
, vol.152
, pp. 1267-1278
-
-
Furstenthal, L.1
Kaiser, B.K.2
Swanson, C.3
Jackson, P.K.4
-
7
-
-
0034665635
-
NPAT by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription
-
NPAT by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription. Genes Dev. 14, 2298-2313 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 2298-2313
-
-
Ma, T.1
-
8
-
-
0034665757
-
NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription
-
Zhao, J. et al. NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription. Genes Dev. 14, 2283-2297 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 2283-2297
-
-
Zhao, J.1
-
9
-
-
0034730321
-
Nucleophosmin/B23 is a target of Cdk2/Cyclin E in centrosome duplication
-
Okuda, M. et al. Nucleophosmin/B23 is a target of Cdk2/Cyclin E in centrosome duplication. Cell 103, 127-140 (2000).
-
(2000)
Cell
, vol.103
, pp. 127-140
-
-
Okuda, M.1
-
10
-
-
0035854383
-
The mouse Mps1p-like kinase regulates centrosome duplication
-
Fisk, H.A. & Winey, M. The mouse Mps1p-like kinase regulates centrosome duplication. Cell 106, 95-104 (2001).
-
(2001)
Cell
, vol.106
, pp. 95-104
-
-
Fisk, H.A.1
Winey, M.2
-
11
-
-
0030925231
-
Cyclin E-CDK2 is a regulator of p27Kip1
-
Sheaff, R. J. et al. Cyclin E-CDK2 is a regulator of p27Kip1. Genes Dev. 11, 1464-1478 (1997).
-
(1997)
Genes Dev.
, vol.11
, pp. 1464-1478
-
-
Sheaff, R.J.1
-
12
-
-
0030847760
-
Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27
-
Vlach, J., Hennecke, S. & Amati, B. Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27. EMBO J. 16, 5334-5344 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 5334-5344
-
-
Vlach, J.1
Hennecke, S.2
Amati, B.3
-
13
-
-
0034004129
-
Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase
-
Zou, L. & Stillman, B. Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase. Mol. Cell. Biol. 20, 3086-3096 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3086-3096
-
-
Zou, L.1
Stillman, B.2
-
14
-
-
0035812709
-
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
-
Koepp, D.M. et al. Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase. Science 294, 173-177 (2001).
-
(2001)
Science
, vol.294
, pp. 173-177
-
-
Koepp, D.M.1
-
15
-
-
0033556238
-
Phosphorylation of mammalian CDC6 by Cyclin A/CDK2 regulates its sebcellular localization
-
Petersen, B.O., Lukas, J., Sorensen, C.S., Bartek, J. & Helin, K. Phosphorylation of mammalian CDC6 by Cyclin A/CDK2 regulates its sebcellular localization. EMBO J. 2, 396-410 (1999).
-
(1999)
EMBO J.
, vol.2
, pp. 396-410
-
-
Petersen, B.O.1
Lukas, J.2
Sorensen, C.S.3
Bartek, J.4
Helin, K.5
-
16
-
-
0001616078
-
A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-cdk2 during cell cycle progression
-
Sorensen, C.S. et al. A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-cdk2 during cell cycle progression. Mol. Cell. Biol. 21, 3692-3703 (2001)
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3692-3703
-
-
Sorensen, C.S.1
-
17
-
-
0033145516
-
Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A
-
Meraldi, P., Lukas, J., Fry, A.M., Bartek, J. & Nigg, E.A. Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nat. Cell Biol. 1, 88-93 (1999).
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 88-93
-
-
Meraldi, P.1
Lukas, J.2
Fry, A.M.3
Bartek, J.4
Nigg, E.A.5
-
18
-
-
0026583746
-
Cyclin A is required at two points in the human cell cycle
-
Pagano, M., Pepperkok, R., Verde, F., Ansorge, W. & Draetta, G. Cyclin A is required at two points in the human cell cycle. EMBO J. 11, 961-971 (1992)
-
(1992)
EMBO J.
, vol.11
, pp. 961-971
-
-
Pagano, M.1
Pepperkok, R.2
Verde, F.3
Ansorge, W.4
Draetta, G.5
-
19
-
-
0027298902
-
The cdk2 kinase is required for the G1-to-S transition in mammalian cells
-
Tsai, L.H., Lees, E., Faha, B., Harlow, E. & Riabowol, K. The cdk2 kinase is required for the G1-to-S transition in mammalian cells. Oncogene 8, 1593-1602 (1993).
-
(1993)
Oncogene
, vol.8
, pp. 1593-1602
-
-
Tsai, L.H.1
Lees, E.2
Faha, B.3
Harlow, E.4
Riabowol, K.5
-
20
-
-
0027742184
-
Distinct roles for cyclin-dependent kinases in cell cycle control
-
Van den Heuvel, S., & Harlow, E. Distinct roles for cyclin-dependent kinases in cell cycle control. Science 262, 2050-2054 (1993).
-
(1993)
Science
, vol.262
, pp. 2050-2054
-
-
Van den Heuvel, S.1
Harlow, E.2
-
21
-
-
0028909645
-
Human cyclin E, a nuclear protein essential for the G1-to-S phase transition
-
Ohtsubo, M., Theodoras, A.M., Schumacher, J., Roberts, J.M. & Pagano, M. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol. Cell. Biol. 15, 2612-2624 (1995).
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2612-2624
-
-
Ohtsubo, M.1
Theodoras, A.M.2
Schumacher, J.3
Roberts, J.M.4
Pagano, M.5
-
22
-
-
0034745051
-
S and G2 phase roles for cdk2 revealed by inducible expression of a dominant-negative mutant in human cells
-
Hu, B., Mitra, J., van den Heuvel, S. & Enders, G.H. S and G2 phase roles for cdk2 revealed by inducible expression of a dominant-negative mutant in human cells. Mol. Cell. Biol. 21, 2755-2766 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 2755-2766
-
-
Hu, B.1
Mitra, J.2
Van den Heuvel, S.3
Enders, G.H.4
-
23
-
-
0041327168
-
Proliferation of cancer cells despite CDK2 inhibition
-
Tetsu, O. & McCormick, F. Proliferation of cancer cells despite CDK2 inhibition. Cancer Cell 3, 233-245 (2003).
-
(2003)
Cancer Cell
, vol.3
, pp. 233-245
-
-
Tetsu, O.1
McCormick, F.2
-
24
-
-
0029566108
-
A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
-
Schwenk, F., Baron, U. & Ralewsky, K. A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res. 23, 5080-5081 (1995).
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 5080-5081
-
-
Schwenk, F.1
Baron, U.2
Ralewsky, K.3
-
25
-
-
0030918714
-
Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases
-
Zarkowska, T. & Mittnacht, S. Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases. J. Biol. Chem. 272, 12738-12746 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12738-12746
-
-
Zarkowska, T.1
Mittnacht, S.2
-
26
-
-
0034906982
-
Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I
-
Prieto, I. et al. Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I. Nat. Cell Biol. 3, 761-766 (2001).
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 761-766
-
-
Prieto, I.1
-
27
-
-
0027958447
-
The gene encoding a major component of the lateral elements of synaptonemal complexes of the rat is related to X-linked lymphocyte-regulated genes
-
Lammers, J.H. et al. The gene encoding a major component of the lateral elements of synaptonemal complexes of the rat is related to X-linked lymphocyte-regulated genes. Mol. Cell. Biol. 14, 1137-1146 (1994).
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1137-1146
-
-
Lammers, J.H.1
-
28
-
-
0027091588
-
A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes
-
Meuwissen, R.L. et al. A coiled-coil related protein specific for synapsed regions of meiotic prophase chromosomes. EMBO J. 11, 5091-5100 (1992).
-
(1992)
EMBO J.
, vol.11
, pp. 5091-5100
-
-
Meuwissen, R.L.1
-
29
-
-
0030061451
-
Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity
-
Guadagno, T.M. & Newport, J.W. Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity. Cell 84, 73-82 (1996).
-
(1996)
Cell
, vol.84
, pp. 73-82
-
-
Guadagno, T.M.1
Newport, J.W.2
-
30
-
-
0031771752
-
Cyclin A1 is required for meiosis in the male mouse
-
Liu, D. et al, Cyclin A1 is required for meiosis in the male mouse. Nat. Genet 20, 377-380 (1998).
-
(1998)
Nat. Genet.
, vol.20
, pp. 377-380
-
-
Liu, D.1
-
31
-
-
0031030730
-
Delayed early embryonic lethality following disruption of the murine cyclin A2 gene
-
Murphy, M. et al. Delayed early embryonic lethality following disruption of the murine cyclin A2 gene. Nat. Genet. 15, 83-86 (1997).
-
(1997)
Nat. Genet.
, vol.15
, pp. 83-86
-
-
Murphy, M.1
-
32
-
-
0041308632
-
Cyclin E function in the mouse
-
in the press
-
Geng, Y. et al Cyclin E function in the mouse. Cell (in the press).
-
Cell
-
-
Geng, Y.1
-
33
-
-
0141737069
-
Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells
-
in the press
-
Parisi, T. et al. Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells. EMBO J. (in the press).
-
EMBO J.
-
-
Parisi, T.1
-
34
-
-
0037131309
-
The oncogenic activity of Cyclin E is not confined to Cdk2 activation alone but relies on several other, distinct functions of the protein
-
Geisen, C. & Moroy, T. The oncogenic activity of Cyclin E is not confined to Cdk2 activation alone but relies on several other, distinct functions of the protein. J. Biol. Chem. 277, 39909-39918 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39909-39918
-
-
Geisen, C.1
Moroy, T.2
-
35
-
-
0034058708
-
A screen for modifiers of Cyclin E function in Drosophila melanogaster identifies Cdk2 mutations, revealing the insignificance of putative phosphorylation sites in Cdk2
-
Lane, M.E. et al. A screen for modifiers of Cyclin E function in Drosophila melanogaster identifies Cdk2 mutations, revealing the insignificance of putative phosphorylation sites in Cdk2. Genetics 155, 233-244 (2000).
-
(2000)
Genetics
, vol.155
, pp. 233-244
-
-
Lane, M.E.1
-
36
-
-
0037172662
-
The spindle checkpoint kinase bub1 and cyclin e/cdk2 both contribute to the establishment of meiotic metaphase arrest by cytostatic factor
-
Tunquist, B.J., Schwab, M.S., Chen, L.G. & Maller, J.L. The spindle checkpoint kinase bub1 and cyclin e/cdk2 both contribute to the establishment of meiotic metaphase arrest by cytostatic factor. Curr. Biol. 12, 1027-1033 (2002).
-
(2002)
Curr. Biol.
, vol.12
, pp. 1027-1033
-
-
Tunquist, B.J.1
Schwab, M.S.2
Chen, L.G.3
Maller, J.L.4
-
37
-
-
0035084060
-
Localization of two mammalian cyelin dependent kinases during mammalian meiosis
-
Ashley, T., Walpita, D. & de Rooij, D.G. Localization of two mammalian cyelin dependent kinases during mammalian meiosis. J. Cell Sci. 114, 685-693 (2001).
-
(2001)
J. Cell Sci.
, vol.114
, pp. 685-693
-
-
Ashley, T.1
Walpita, D.2
De Rooij, D.G.3
-
38
-
-
0037150670
-
Sex matters in meiosis
-
Hunt, P.A. & Hassold, T.J. Sex matters in meiosis. Science 296, 2181-2183 (2002).
-
(2002)
Science
, vol.296
, pp. 2181-2183
-
-
Hunt, P.A.1
Hassold, T.J.2
-
39
-
-
0036384175
-
Meiotic prophase abnormalities and metaphase cell death in MLH 1-deficient mouse spermatocytes: Insights into regulation of spermatogenic progress
-
Eaker, S., Cobb, J., Pyle, A. & Handel, M.A. Meiotic prophase abnormalities and metaphase cell death in MLH 1-deficient mouse spermatocytes: insights into regulation of spermatogenic progress. Dev. Biol. 249, 85-95 (2002).
-
(2002)
Dev. Biol.
, vol.249
, pp. 85-95
-
-
Eaker, S.1
Cobb, J.2
Pyle, A.3
Handel, M.A.4
-
40
-
-
0033634652
-
The mouse Spoll gene is required for meiotic chromosome synapsis
-
Romanienko, P.J. & Camerini-Otero, R.D. The mouse Spoll gene is required for meiotic chromosome synapsis. Mol Cell 6, 975-987 (2000).
-
(2000)
Mol. Cell
, vol.6
, pp. 975-987
-
-
Romanienko, P.J.1
Camerini-Otero, R.D.2
-
41
-
-
0032039077
-
Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmcl, a germline-specific RecA homolog
-
Pittman, D.L. et al. Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmcl, a germline-specific RecA homolog. Mol. Cell 1, 697-705 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 697-705
-
-
Pittman, D.L.1
-
42
-
-
0034192849
-
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice
-
Kneitz, B. et al. MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. Genes Dev. 14, 1085-1097 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 1085-1097
-
-
Kneitz, B.1
-
43
-
-
0033105760
-
Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis
-
de Vries, S.S. et al. Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis. Genes Dev. 13, 523-531 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 523-531
-
-
De Vries, S.S.1
-
44
-
-
0033975302
-
The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility
-
Yuan, L. et al. The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility. Mol. Cell 5, 73-83 (2000).
-
(2000)
Mol. Cell
, vol.5
, pp. 73-83
-
-
Yuan, L.1
-
45
-
-
0029781869
-
Centromere and telomere movements during early meiotic prophase of mouse and man are associated with the onset of chromosome pairing
-
Scherthan, H. et al. Centromere and telomere movements during early meiotic prophase of mouse and man are associated with the onset of chromosome pairing. J. Cell Biol. 134, 1109-1125 (1996).
-
(1996)
J. Cell Biol.
, vol.134
, pp. 1109-1125
-
-
Scherthan, H.1
-
46
-
-
0035754080
-
To cycle or not to cycle a critical decision in cancer
-
Malumbres, M. & Barbacid, M. To cycle or not to cycle a critical decision in cancer. Nat. Rev. Cancer 1, 222-231 (2001).
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 222-231
-
-
Malumbres, M.1
Barbacid, M.2
-
47
-
-
0031675550
-
Drosophila engrailed car substitute for mouse Engrailedl function in mid-hindbrain, but not limb development
-
Hanks, M.C. et al. Drosophila engrailed car substitute for mouse Engrailedl function in mid-hindbrain, but not limb development. Development 125, 4521-4530 (1998).
-
(1998)
Development
, vol.125
, pp. 4521-4530
-
-
Hanks, M.C.1
-
48
-
-
0025780879
-
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
-
Tybulewicz, V.L., Crawford, C.E., Jackson, P.K., Bronson, R.T. & Mulligan, R.C. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell 65, 1153-1163 (1991).
-
(1991)
Cell
, vol.65
, pp. 1153-1163
-
-
Tybulewicz, V.L.1
Crawford, C.E.2
Jackson, P.K.3
Bronson, R.T.4
Mulligan, R.C.5
-
49
-
-
0027321548
-
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells
-
Nagy, A., Rossant, J., Nagy, R., Abromow-Newerly, W. & Roder, J.C. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90, 8424-8428 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8424-8428
-
-
Nagy, A.1
Rossant, J.2
Nagy, R.3
Abromow-Newerly, W.4
Roder, J.C.5
-
50
-
-
0035803395
-
Wide spectrum of tumors in knock-in mice carrying a Cdk 4 protein insensitive to INK4 inhibitors
-
Sotillo, R. et al. Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors. EMBO J. 20, 6637-6647 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 6637-6647
-
-
Sotillo, R.1
-
51
-
-
0034600841
-
Limited overlapping roles of P15(INK4b) and P18 (INK4c) cell cycle inhibitors in proliferation and tumorigenesis
-
Latres, E. et al. Limited overlapping roles of P15(INK4b) and P18 (INK4c) cell cycle inhibitors in proliferation and tumorigenesis. EMBO J. 19, 3496-3506 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 3496-3506
-
-
Latres, E.1
-
52
-
-
0002515974
-
Meiotic studies in humans
-
(ed. Rooney, D.E.) (Oxford University Press, Oxford
-
Hulten, M., Barlow, A.L. & Tease, C. Meiotic studies in humans. In Human Cytogenetics: Constitutional Analysis. A Practical Approach 3rd edn. (ed. Rooney, D.E.) 211-236 (Oxford University Press, Oxford, 2001).
-
(2001)
Human Cytogenetics: Constitutional Analysis. A Practical Approach 3rd Edn.
, pp. 211-236
-
-
Hulten, M.1
Barlow, A.L.2
Tease, C.3
|