Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function

Nature Chemical Biology

Volumn 6, Issue 5, 2010, Pages 359-368

  Kwiatkowski, Nicholas ^a,b   Jelluma, Nannette ^c   Filippakopoulos, Panagis ^d,e   Soundararajan, Meera ^d,e   Manak, Michael S ^f   Kwon, Mijung ^a   Choi, Hwan Geun ^a,b   Sim, Taebo ^a,b   Deveraux, Quinn L ^g   Rottmann, Sabine ^g   Pellman, David ^a   Shah, Jagesh V ^f   Kops, Geert J P L ^c   Knapp, Stefan ^d,e   Gray, Nathanael S ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA B KINASE; MPS1 PROTEIN; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE; PROTEIN MAD1; PROTEIN MAD2; SMALL MOLECULE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANEUPLOIDY; ARTICLE; CELL CYCLE; CELL FUNCTION; CELL VIABILITY; CENTROMERE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME STRUCTURE, FUNCTION AND VARIABILITY; HUMAN; HUMAN CELL; MITOSIS; MITOSIS RATE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; SEQUENCE HOMOLOGY;

EID: 77951299152     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.345     Document Type: Article

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