Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 13, 2004, Pages 4459-4464

  Michel, Loren ^a   Diaz Rodriguez, Elena ^a   Narayan, Gopeshwar ^b   Hernando, Eva ^a   Murty, Vundavalli V V S ^b   Benezra, Robert ^a,c  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Columbia University ^*  (United States)

^c Weill Cornell Graduate School of Biomedical Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN B; PROTEIN MAD2;

ANAPHASE; ARTICLE; CELL DEATH; CHROMOSOME CONDENSATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LUNG TUMOR; MAD2 GENE; MITOSIS; MITOSIS SPINDLE; MULTINUCLEAR CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; RNA INTERFERENCE; SOMATIC CELL; SPINDLE CELL; TUMOR SUPPRESSOR GENE;

BASE SEQUENCE; CALCIUM-BINDING PROTEINS; CELL CYCLE; CELL CYCLE PROTEINS; CELL DEATH; CHROMOSOMES, HUMAN; CYCLIN B; GENE DELETION; GENES, ESSENTIAL; GENES, TUMOR SUPPRESSOR; HUMANS; MICROSCOPY, FLUORESCENCE; MITOSIS; OPEN READING FRAMES; REPRESSOR PROTEINS; TRANSFECTION;

ANIMALIA;

EID: 1842533070     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0306069101     Document Type: Article

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