-
1
-
-
34247232176
-
Phosphorylation of caspase-9 by CDK1/ cyclin B1 protects mitotic cells against apoptosis
-
Allan, L. A., and P. R. Clarke. 2007. Phosphorylation of caspase-9 by CDK1/ cyclin B1 protects mitotic cells against apoptosis. Mol. Cell 26:301-310.
-
(2007)
Mol. Cell
, vol.26
, pp. 301-310
-
-
Allan, L.A.1
Clarke, P.R.2
-
2
-
-
70350347735
-
Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2
-
Andersen, J. L., C. E. Johnson, C. D. Freel, A. B. Parrish, J. L. Day, M. R. Buchakjian, L. K. Nutt, J. W. Thompson, M. A. Moseley, and S. Kornbluth. 2009. Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2. EMBO J. 28:3216-3227.
-
(2009)
EMBO J.
, vol.28
, pp. 3216-3227
-
-
Andersen, J.L.1
Johnson, C.E.2
Freel, C.D.3
Parrish, A.B.4
Day, J.L.5
Buchakjian, M.R.6
Nutt, L.K.7
Thompson, J.W.8
Moseley, M.A.9
Kornbluth, S.10
-
3
-
-
37049020700
-
Distinct sequence elements of cyclin B1 promote localization to chromatin, centrosomes, and kinetochores during mitosis
-
Bentley, A. M., G. Normand, J. Hoyt, and R. W. King. 2007. Distinct sequence elements of cyclin B1 promote localization to chromatin, centrosomes, and kinetochores during mitosis. Mol. Biol. Cell 18:4847-4858.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 4847-4858
-
-
Bentley, A.M.1
Normand, G.2
Hoyt, J.3
King, R.W.4
-
4
-
-
0029417238
-
Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
-
Blangy, A., H. A. Lane, P. d'Herin, M. Harper, M. Kress, and E. A. Nigg. 1995. Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell 83:1159-1169.
-
(1995)
Cell
, vol.83
, pp. 1159-1169
-
-
Blangy, A.1
Lane, H.A.2
D'herin, P.3
Harper, M.4
Kress, M.5
Nigg, E.A.6
-
5
-
-
0042466637
-
Interdimer processing mechanism of procaspase-8 activation
-
Chang, D. W., Z. Xing, V. L. Capacio, M. E. Peter, and X. Yang. 2003. Interdimer processing mechanism of procaspase-8 activation. EMBO J. 22: 4132-4142.
-
(2003)
EMBO J.
, vol.22
, pp. 4132-4142
-
-
Chang, D.W.1
Xing, Z.2
Capacio, V.L.3
Peter, M.E.4
Yang, X.5
-
6
-
-
33847337318
-
A common coding variant in CASP8 is associated with breast cancer risk
-
Cox, A., A. M. Dunning, M. Garcia-Closas, S. Balasubramanian, M. W. Reed, K. A. Pooley, S. Scollen, C. Baynes, B. A. Ponder, S. Chanock, J. Lissowska, L. Brinton, B. Peplonska, M. C. Southey, J. L. Hopper, M. R. McCredie, G. G. Giles, O. Fletcher, N. Johnson, S. S. dos, I. L. Gibson, S. E. Bojesen, B. G. Nordestgaard, C. K. Axelsson, D. Torres, U. Hamann, C. Justenhoven, H. Brauch, J. Chang-Claude, S. Kropp, A. Risch, S. Wang- Gohrke, P. Schurmann, N. Bogdanova, T. Dork, R. Fagerholm, K. Aaltonen, C. Blomqvist, H. Nevanlinna, S. Seal, A. Renwick, M. R. Stratton, N. Rahman, S. Sangrajrang, D. Hughes, F. Odefrey, P. Brennan, A. B. Spurdle, G. Chenevix-Trench, J. Beesley, A. Mannermaa, J. Hartikainen, V. Kataja, V. M. Kosma, F. J. Couch, J. E. Olson, E. L. Goode, A. Broeks, M. K. Schmidt, F. B. Hogervorst, L. J. Van't Veer, D. Kang, K. Y. Yoo, D. Y. Noh, S. H. Ahn, S. Wedren, P. Hall, Y. L. Low, J. Liu, R. L. Milne, G. Ribas, A. Gonzalez-Neira, J. Benitez, A. J. Sigurdson, D. L. Stredrick, B. H. Alexander, J. P. Struewing, P. D. Pharoah, and D. F. Easton. 2007. A common coding variant in CASP8 is associated with breast cancer risk. Nat. Genet. 39:352-358.
-
(2007)
Nat. Genet.
, vol.39
, pp. 352-358
-
-
Cox, A.1
Dunning, A.M.2
Garcia-Closas, M.3
Balasubramanian, S.4
Reed, M.W.5
Pooley, K.A.6
Scollen, S.7
Baynes, C.8
Ponder, B.A.9
Chanock, S.10
Lissowska, J.11
Brinton, L.12
Peplonska, B.13
Southey, M.C.14
Hopper, J.L.15
Mccredie, M.R.16
Giles, G.G.17
Fletcher, O.18
Johnson, N.19
Dos, S.S.20
Gibson, I.L.21
Bojesen, S.E.22
Nordestgaard, B.G.23
Axelsson, C.K.24
Torres, D.25
Hamann, U.26
Justenhoven, C.27
Brauch, H.28
Chang-Claude, J.29
Kropp, S.30
Risch, A.31
Wang-Gohrke, S.32
Schurmann, P.33
Bogdanova, N.34
Dork, T.35
Fagerholm, R.36
Aaltonen, K.37
Blomqvist, C.38
Nevanlinna, H.39
Seal, S.40
Renwick, A.41
Stratton, M.R.42
Rahman, N.43
Sangrajrang, S.44
Hughes, D.45
Odefrey, F.46
Brennan, P.47
Spurdle, A.B.48
Chenevix-Trench, G.49
Beesley, J.50
Mannermaa, A.51
Hartikainen, J.52
Kataja, V.53
Kosma, V.M.54
Couch, F.J.55
Olson, J.E.56
Goode, E.L.57
Broeks, A.58
Schmidt, M.K.59
Hogervorst, F.B.60
van't Veer, L.J.61
Kang, D.62
Yoo, K.Y.63
Noh, D.Y.64
Ahn, S.H.65
Wedren, S.66
Hall, P.67
Low, Y.L.68
Liu, J.69
Milne, R.L.70
Ribas, G.71
Gonzalez-Neira, A.72
Benitez, J.73
Sigurdson, A.J.74
Stredrick, D.L.75
Alexander, B.H.76
Struewing, J.P.77
Pharoah, P.D.78
Easton, D.F.79
more..
-
7
-
-
33646542701
-
Src kinase phosphorylates caspase-8 on Tyr380: a novel mechanism of apoptosis suppression
-
Cursi, S., A. Rufini, V. Stagni, I. Condo, V. Matafora, A. Bachi, A. P. Bonifazi, L. Coppola, G. Superti-Furga, R. Testi, and D. Barila. 2006. Src kinase phosphorylates caspase-8 on Tyr380: a novel mechanism of apoptosis suppression. EMBO J. 25:1895-1905.
-
(2006)
EMBO J.
, vol.25
, pp. 1895-1905
-
-
Cursi, S.1
Rufini, A.2
Stagni, V.3
Condo, I.4
Matafora, V.5
Bachi, A.6
Bonifazi, A.P.7
Coppola, L.8
Superti-Furga, G.9
Testi, R.10
Barila, D.11
-
8
-
-
42449123761
-
Expansion and evolution of cell death programmes
-
Degterev, A., and J. Yuan. 2008. Expansion and evolution of cell death programmes. Nat. Rev. Mol. Cell. Biol. 9:378-390.
-
(2008)
Nat. Rev. Mol. Cell. Biol.
, vol.9
, pp. 378-390
-
-
Degterev, A.1
Yuan, J.2
-
9
-
-
67349160732
-
Caspase-8 in cancer biology and therapy
-
Fulda, S. 2009. Caspase-8 in cancer biology and therapy. Cancer Lett. 281: 128-133.
-
(2009)
Cancer Lett.
, vol.281
, pp. 128-133
-
-
Fulda, S.1
-
10
-
-
0035855626
-
Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer
-
Fulda, S., M. U. Kufer, E. Meyer, V. F. van, B. Dockhorn-Dworniczak, and K. M. Debatin. 2001. Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer. Oncogene 20:5865-5877.
-
(2001)
Oncogene
, vol.20
, pp. 5865-5877
-
-
Fulda, S.1
Kufer, M.U.2
Meyer, E.3
Van, V.F.4
Dockhorn-Dworniczak, B.5
Debatin, K.M.6
-
11
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D., and R. A. Weinberg. 2000. The hallmarks of cancer. Cell 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
12
-
-
0037108859
-
Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines
-
Harada, K., S. Toyooka, N. Shivapurkar, A. Maitra, J. L. Reddy, H. Matta, K. Miyajima, C. F. Timmons, G. E. Tomlinson, D. Mastrangelo, R. J. Hay, P. M. Chaudhary, and A. F. Gazdar. 2002. Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines. Cancer Res. 62:5897-5901.
-
(2002)
Cancer Res.
, vol.62
, pp. 5897-5901
-
-
Harada, K.1
Toyooka, S.2
Shivapurkar, N.3
Maitra, A.4
Reddy, J.L.5
Matta, H.6
Miyajima, K.7
Timmons, C.F.8
Tomlinson, G.E.9
Mastrangelo, D.10
Hay, R.J.11
Chaudhary, P.M.12
Gazdar, A.F.13
-
13
-
-
0028348704
-
Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors
-
Holtrich, U., G. Wolf, A. Brauninger, T. Karn, B. Bohme, H. Rubsamen- Waigmann, and K. Strebhardt. 1994. Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors. Proc. Natl. Acad. Sci. U. S. A. 91:1736-1740.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 1736-1740
-
-
Holtrich, U.1
Wolf, G.2
Brauninger, A.3
Karn, T.4
Bohme, B.5
Rubsamen-Waigmann, H.6
Strebhardt, K.7
-
14
-
-
68349154339
-
Reconstitution of the death-inducing signaling complex reveals a substrate switch that determines CD95-mediated death or survival
-
Hughes, M. A., N. Harper, M. Butterworth, K. Cain, G. M. Cohen, and M. MacFarlane. 2009. Reconstitution of the death-inducing signaling complex reveals a substrate switch that determines CD95-mediated death or survival. Mol. Cell 35:265-279.
-
(2009)
Mol. Cell
, vol.35
, pp. 265-279
-
-
Hughes, M.A.1
Harper, N.2
Butterworth, M.3
Cain, K.4
Cohen, G.M.5
Macfarlane, M.6
-
15
-
-
0036547417
-
Death and anti-death: tumour resistance to apoptosis
-
Igney, F. H., and P. H. Krammer. 2002. Death and anti-death: tumour resistance to apoptosis. Nat. Rev. Cancer 2:277-288.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 277-288
-
-
Igney, F.H.1
Krammer, P.H.2
-
16
-
-
0037322744
-
Active cyclin B1-Cdk1 first appears on centrosomes in prophase
-
Jackman, M., C. Lindon, E. A. Nigg, and J. Pines. 2003. Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nat. Cell Biol. 5:143- 148.
-
(2003)
Nat. Cell Biol.
, vol.5
-
-
Jackman, M.1
Lindon, C.2
Nigg, E.A.3
Pines, J.4
-
17
-
-
43749104015
-
Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells
-
Jiang, M., K. Zhu, J. Grenet, and J. M. Lahti. 2008. Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells. Biochim. Biophys. Acta 1783:1055-1067.
-
(2008)
Biochim. Biophys. Acta
, vol.1783
, pp. 1055-1067
-
-
Jiang, M.1
Zhu, K.2
Grenet, J.3
Lahti, J.M.4
-
18
-
-
39149084389
-
Silencing of mammalian genes by tetracycline-inducible shRNA expression
-
Kappel, S., Y. Matthess, M. Kaufmann, and K. Strebhardt. 2007. Silencing of mammalian genes by tetracycline-inducible shRNA expression. Nat. Protoc. 2:3257-3269.
-
(2007)
Nat. Protoc.
, vol.2
, pp. 3257-3269
-
-
Kappel, S.1
Matthess, Y.2
Kaufmann, M.3
Strebhardt, K.4
-
19
-
-
33750054108
-
Tumor inhibition by genomically integrated inducible RNAi-cassettes
-
Kappel, S., Y. Matthess, B. Zimmer, M. Kaufmann, and K. Strebhardt. 2006. Tumor inhibition by genomically integrated inducible RNAi-cassettes. Nucleic Acids Res. 34:4527-4536.
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 4527-4536
-
-
Kappel, S.1
Matthess, Y.2
Zimmer, B.3
Kaufmann, M.4
Strebhardt, K.5
-
20
-
-
10344236486
-
Aurora-kinase inhibitors as anticancer agents
-
Keen, N., and S. Taylor. 2004. Aurora-kinase inhibitors as anticancer agents. Nat. Rev. Cancer 4:927-936.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 927-936
-
-
Keen, N.1
Taylor, S.2
-
21
-
-
0035937189
-
Chromosome condensation by a human condensin complex in Xenopus egg extracts
-
Kimura, K., O. Cuvier, and T. Hirano. 2001. Chromosome condensation by a human condensin complex in Xenopus egg extracts. J. Biol. Chem. 276: 5417-5420.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5417-5420
-
-
Kimura, K.1
Cuvier, O.2
Hirano, T.3
-
22
-
-
0037279654
-
The active caspase-8 heterotetramer is formed at the CD95 DISC
-
Lavrik, I., A. Krueger, I. Schmitz, S. Baumann, H. Weyd, P. H. Krammer, and S. Kirchhoff. 2003. The active caspase-8 heterotetramer is formed at the CD95 DISC. Cell Death. Differ. 10:144-145.
-
(2003)
Cell Death. Differ.
, vol.10
, pp. 144-145
-
-
Lavrik, I.1
Krueger, A.2
Schmitz, I.3
Baumann, S.4
Weyd, H.5
Krammer, P.H.6
Kirchhoff, S.7
-
23
-
-
0035754080
-
To cycle or not to cycle: a critical decision in cancer
-
Malumbres, M., and M. Barbacid. 2001. To cycle or not to cycle: a critical decision in cancer. Nat. Rev. Cancer 1:222-231.
-
(2001)
Nat. Rev. Cancer
, vol.1
, pp. 222-231
-
-
Malumbres, M.1
Barbacid, M.2
-
24
-
-
60749109846
-
Cell cycle, CDKs and cancer: a changing paradigm
-
Malumbres, M., and M. Barbacid. 2009. Cell cycle, CDKs and cancer: a changing paradigm. Nat. Rev. Cancer 9:153-166.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
25
-
-
0029832293
-
Expression of cell cycle-regulated proteins in prostate cancer
-
Mashal, R. D., S. Lester, C. Corless, J. P. Richie, R. Chandra, K. J. Propert, and A. Dutta. 1996. Expression of cell cycle-regulated proteins in prostate cancer. Cancer Res. 56:4159-4163.
-
(1996)
Cancer Res.
, vol.56
, pp. 4159-4163
-
-
Mashal, R.D.1
Lester, S.2
Corless, C.3
Richie, J.P.4
Chandra, R.5
Propert, K.J.6
Dutta, A.7
-
26
-
-
18344383777
-
Conditional inhibition of cancer cell proliferation by tetracycline- responsive, H1 promoter-driven silencing of PLK1
-
Matthess, Y., S. Kappel, B. Spankuch, B. Zimmer, M. Kaufmann, and K. Strebhardt. 2005. Conditional inhibition of cancer cell proliferation by tetracycline- responsive, H1 promoter-driven silencing of PLK1. Oncogene 24: 2973-2980.
-
(2005)
Oncogene
, vol.24
, pp. 2973-2980
-
-
Matthess, Y.1
Kappel, S.2
Spankuch, B.3
Zimmer, B.4
Kaufmann, M.5
Strebhardt, K.6
-
27
-
-
0030925774
-
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
-
Medema, J. P., C. Scaffidi, F. C. Kischkel, A. Shevchenko, M. Mann, P. H. Krammer, and M. E. Peter. 1997. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16:2794-2804.
-
(1997)
EMBO J.
, vol.16
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffidi, C.2
Kischkel, F.C.3
Shevchenko, A.4
Mann, M.5
Krammer, P.H.6
Peter, M.E.7
-
28
-
-
0032579490
-
An induced proximity model for caspase-8 activation
-
Muzio, M., B. R. Stockwell, H. R. Stennicke, G. S. Salvesen, and V. M. Dixit. 1998. An induced proximity model for caspase-8 activation. J. Biol. Chem. 273:2926-2930.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2926-2930
-
-
Muzio, M.1
Stockwell, B.R.2
Stennicke, H.R.3
Salvesen, G.S.4
Dixit, V.M.5
-
29
-
-
0035235736
-
Mitotic kinases as regulators of cell division and its checkpoints
-
Nigg, E. A. 2001. Mitotic kinases as regulators of cell division and its checkpoints. Nat. Rev. Mol. Cell. Biol. 2:21-32.
-
(2001)
Nat. Rev. Mol. Cell. Biol.
, vol.2
, pp. 21-32
-
-
Nigg, E.A.1
-
30
-
-
0025246110
-
Universal control mechanism regulating onset of M-phase
-
Nurse, P. 1990. Universal control mechanism regulating onset of M-phase. Nature 344:503-508.
-
(1990)
Nature
, vol.344
, pp. 503-508
-
-
Nurse, P.1
-
31
-
-
0025370462
-
In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase
-
Peter, M., J. Nakagawa, M. Doree, J. C. Labbe, and E. A. Nigg. 1990. In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase. Cell 61:591-602.
-
(1990)
Cell
, vol.61
, pp. 591-602
-
-
Peter, M.1
Nakagawa, J.2
Doree, M.3
Labbe, J.C.4
Nigg, E.A.5
-
32
-
-
30444449969
-
Mitosis: a matter of getting rid of the right protein at the right time
-
Pines, J. 2006. Mitosis: a matter of getting rid of the right protein at the right time. Trends Cell Biol. 16:55-63.
-
(2006)
Trends Cell Biol.
, vol.16
, pp. 55-63
-
-
Pines, J.1
-
33
-
-
0035690584
-
CD28 signaling via VAV/SLP-76 adaptors: regulation of cytokine transcription independent of TCR ligation
-
Raab, M., S. Pfister, and C. E. Rudd. 2001. CD28 signaling via VAV/SLP-76 adaptors: regulation of cytokine transcription independent of TCR ligation. Immunity 15:921-933.
-
(2001)
Immunity
, vol.15
, pp. 921-933
-
-
Raab, M.1
Pfister, S.2
Rudd, C.E.3
-
34
-
-
0028344074
-
The T-cell antigen CD5 acts as a receptor and substrate for the protein-tyrosine kinase p56lck
-
Raab, M., M. Yamamoto, and C. E. Rudd. 1994. The T-cell antigen CD5 acts as a receptor and substrate for the protein-tyrosine kinase p56lck. Mol. Cell. Biol. 14:2862-2870.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2862-2870
-
-
Raab, M.1
Yamamoto, M.2
Rudd, C.E.3
-
35
-
-
43149093993
-
Inhibition of polo-like kinase 1 by blocking polo-box domain-dependent protein-protein interactions
-
Reindl, W., J. Yuan, A. Kramer, K. Strebhardt, and T. Berg. 2008. Inhibition of polo-like kinase 1 by blocking polo-box domain-dependent protein-protein interactions. Chem. Biol. 15:459-466.
-
(2008)
Chem. Biol.
, vol.15
, pp. 459-466
-
-
Reindl, W.1
Yuan, J.2
Kramer, A.3
Strebhardt, K.4
Berg, T.5
-
36
-
-
0034717570
-
Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex
-
Rudner, A. D., and A. W. Murray. 2000. Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex. J. Cell Biol. 149:1377-1390.
-
(2000)
J. Cell Biol.
, vol.149
, pp. 1377-1390
-
-
Rudner, A.D.1
Murray, A.W.2
-
38
-
-
37549062115
-
Caspase-8 interacts with the p85 subunit of phosphatidylinositol 3-kinase to regulate cell adhesion and motility
-
Senft, J., B. Helfer, and S. M. Frisch. 2007. Caspase-8 interacts with the p85 subunit of phosphatidylinositol 3-kinase to regulate cell adhesion and motility. Cancer Res. 67:11505-11509.
-
(2007)
Cancer Res.
, vol.67
, pp. 11505-11509
-
-
Senft, J.1
Helfer, B.2
Frisch, S.M.3
-
39
-
-
33645802169
-
Cyclin-dependent kinase pathways as targets for cancer treatment
-
Shapiro, G. I. 2006. Cyclin-dependent kinase pathways as targets for cancer treatment. J. Clin. Oncol. 24:1770-1783.
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 1770-1783
-
-
Shapiro, G.I.1
-
40
-
-
0029905073
-
Molecular ordering of the Fas-apoptotic pathway: the Fas/ APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
-
Srinivasula, S. M., M. Ahmad, T. Fernandes-Alnemri, G. Litwack, and E. S. Alnemri. 1996. Molecular ordering of the Fas-apoptotic pathway: the Fas/ APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc. Natl. Acad. Sci. U. S. A. 93:14486- 14491.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 14486-14491
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Litwack, G.4
Alnemri, E.S.5
-
41
-
-
77955167321
-
Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy
-
Strebhardt, K. 2010. Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy. Nat. Rev. Drug Discov. 9:643-660.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 643-660
-
-
Strebhardt, K.1
-
42
-
-
33645316142
-
Targeting polo-like kinase 1 for cancer therapy
-
Strebhardt, K., and A. Ullrich. 2006. Targeting polo-like kinase 1 for cancer therapy. Nat. Rev. Cancer 6:321-330.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 321-330
-
-
Strebhardt, K.1
Ullrich, A.2
-
43
-
-
30144434107
-
Potentiation of neuroblastoma metastasis by loss of caspase-8
-
Stupack, D. G., T. Teitz, M. D. Potter, D. Mikolon, P. J. Houghton, V. J. Kidd, J. M. Lahti, and D. A. Cheresh. 2006. Potentiation of neuroblastoma metastasis by loss of caspase-8. Nature 439:95-99.
-
(2006)
Nature
, vol.439
, pp. 95-99
-
-
Stupack, D.G.1
Teitz, T.2
Potter, M.D.3
Mikolon, D.4
Houghton, P.J.5
Kidd, V.J.6
Lahti, J.M.7
Cheresh, D.A.8
-
44
-
-
0034066405
-
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
-
Teitz, T., T. Wei, M. B. Valentine, E. F. Vanin, J. Grenet, V. A. Valentine, F. G. Behm, A. T. Look, J. M. Lahti, and V. J. Kidd. 2000. Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat. Med. 6:529-535.
-
(2000)
Nat. Med.
, vol.6
, pp. 529-535
-
-
Teitz, T.1
Wei, T.2
Valentine, M.B.3
Vanin, E.F.4
Grenet, J.5
Valentine, V.A.6
Behm, F.G.7
Look, A.T.8
Lahti, J.M.9
Kidd, V.J.10
-
45
-
-
33746094659
-
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1
-
Vassilev, L. T., C. Tovar, S. Chen, D. Knezevic, X. Zhao, H. Sun, D. C. Heimbrook, and L. Chen. 2006. Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc. Natl. Acad. Sci. U. S. A. 103:10660-10665.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 10660-10665
-
-
Vassilev, L.T.1
Tovar, C.2
Chen, S.3
Knezevic, D.4
Zhao, X.5
Sun, H.6
Heimbrook, D.C.7
Chen, L.8
-
46
-
-
0035192637
-
Subcellular localization of cyclin B, Cdc2, and p21WAF1/CIP1 in breast cancer. association with prognosis
-
Winters, Z. E., N. C. Hunt, M. J. Bradburn, J. A. Royds, H. Turley, A. L. Harris, and C. J. Norbury. 2001. Subcellular localization of cyclin B, Cdc2, and p21WAF1/CIP1 in breast cancer. association with prognosis. Eur. J. Cancer 37:2405-2412.
-
(2001)
Eur. J. Cancer
, vol.37
, pp. 2405-2412
-
-
Winters, Z.E.1
Hunt, N.C.2
Bradburn, M.J.3
Royds, J.A.4
Turley, H.5
Harris, A.L.6
Norbury, C.J.7
-
47
-
-
0037373901
-
Induction of caspase 8 by interferon gamma renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB
-
Yang, X., M. S. Merchant, M. E. Romero, M. Tsokos, L. H. Wexler, U. Kontny, C. L. Mackall, and C. J. Thiele. 2003. Induction of caspase 8 by interferon gamma renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB. Cancer Res. 63:1122-1129.
-
(2003)
Cancer Res.
, vol.63
, pp. 1122-1129
-
-
Yang, X.1
Merchant, M.S.2
Romero, M.E.3
Tsokos, M.4
Wexler, L.H.5
Kontny, U.6
Mackall, C.L.7
Thiele, C.J.8
-
48
-
-
33645033152
-
Stable gene silencing of cyclin B1 in tumor cells increases susceptibility to taxol and leads to growth arrest in vivo
-
Yuan, J., A. Kramer, Y. Matthess, R. Yan, B. Spankuch, R. Gatje, R. Knecht, M. Kaufmann, and K. Strebhardt. 2006. Stable gene silencing of cyclin B1 in tumor cells increases susceptibility to taxol and leads to growth arrest in vivo. Oncogene 25:1753-1762.
-
(2006)
Oncogene
, vol.25
, pp. 1753-1762
-
-
Yuan, J.1
Kramer, A.2
Matthess, Y.3
Yan, R.4
Spankuch, B.5
Gatje, R.6
Knecht, R.7
Kaufmann, M.8
Strebhardt, K.9
-
49
-
-
4143080409
-
Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells
-
Yuan, J., R. Yan, A. Kramer, F. Eckerdt, M. Roller, M. Kaufmann, and K. Strebhardt. 2004. Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells. Oncogene 23:5843-5852.
-
(2004)
Oncogene
, vol.23
, pp. 5843-5852
-
-
Yuan, J.1
Yan, R.2
Kramer, A.3
Eckerdt, F.4
Roller, M.5
Kaufmann, M.6
Strebhardt, K.7
-
50
-
-
0034602188
-
Role of BAX in the apoptotic response to anticancer agents
-
Zhang, L., J. Yu, B. H. Park, K. W. Kinzler, and B. Vogelstein. 2000. Role of BAX in the apoptotic response to anticancer agents. Science 290:989-992.
-
(2000)
Science
, vol.290
, pp. 989-992
-
-
Zhang, L.1
Yu, J.2
Park, B.H.3
Kinzler, K.W.4
Vogelstein, B.5
|