Targeting the liver stage of malaria parasites: A yet unmet goal

Journal of Medicinal Chemistry

Volumn 55, Issue 3, 2012, Pages 995-1012

  Rodrigues, Tiago ^a   Prudêncio, Miguel ^b   Moreira, Rui ^a   Mota, Maria M ^b   Lopes, Francisca ^a  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^b UNIVERSITY OF LISBON   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

6 BUTYL 4 HYDROXY 7 (2 PHENOXYETHOXY) 3 QUINOLINECARBOXYLIC ACID METHYL ESTER; ALKALOID; ANTIMALARIAL AGENT; ARTEMISININ; ATOVAQUONE; AZATADINE; AZITHROMYCIN; BULAQUINE; CLINDAMYCIN; CYPROHEPTADINE; DIONCOPHYLLINE A; DOXYCYCLINE; FLOXACRINE; KETOTIFEN; LORATADINE; MENOCTONE; PAMAQUINE; PENTAQUINE; PRIMAQUINE; PROGUANIL; PYRIMETHAMINE; QUININE; RIFAMPICIN; SINOCOCULINE; SULFAMETHOXAZOLE; TAFENOQUINE; TERFENADINE; TETRACYCLINE; TRIMETHOPRIM; UNINDEXED DRUG;

ANOPHELES; ANTIMALARIAL ACTIVITY; ANTIMALARIAL DRUG RESISTANCE; ARTICLE; DISEASE SEVERITY; DRUG BIOAVAILABILITY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; DRUG STRUCTURE; ERYTHROCYTE; GAMETOCYTE; HEMOLYTIC ANEMIA; HUMAN; IC 50; LIVER; LIVER CELL; MALARIA; MALARIA CONTROL; MALARIA FALCIPARUM; MEROZOITE; METHEMOGLOBINEMIA; NONHUMAN; PARASITE LOAD; PARASITE TRANSMISSION; PLASMODIUM (LIFE CYCLE STAGE); PLASMODIUM BERGHEI; PLASMODIUM BERGHEI INFECTION; PLASMODIUM CYNOMOLGI; PLASMODIUM FALCIPARUM; PLASMODIUM OVALE MALARIA; PLASMODIUM VIVAX MALARIA; SPOROZOITE; TREATMENT DURATION;

ANIMALS; ANTIMALARIALS; HUMANS; LIFE CYCLE STAGES; LIVER; MALARIA; PLASMODIUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84856909677     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201095h     Document Type: Article

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