-
1
-
-
84858449712
-
Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment
-
Carrara VI, Zwang J, Ashley EA et al. Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment. PloS One 4(2), e4551 (2009).
-
(2009)
PloS One
, vol.4
, Issue.2
-
-
Carrara, V.I.1
Zwang, J.2
Ashley, E.A.3
-
2
-
-
41949110686
-
In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes
-
Ekland EH, Fidock DA. In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes. Int. J. Parasitol. 38(7), 743-747 (2008).
-
(2008)
Int. J. Parasitol.
, vol.38
, Issue.7
, pp. 743-747
-
-
Ekland, E.H.1
Fidock, D.A.2
-
3
-
-
77956280420
-
Spiroindolones a potent compound class for the treatment of malaria
-
Rottmann M, McNamara C, Yeung BKS et al. Spiroindolones, a potent compound class for the treatment of malaria. Science 329(3), 1175-1180 (2010).
-
(2010)
Science
, vol.329
, Issue.3
, pp. 1175-1180
-
-
Rottmann, M.1
McNamara, C.2
Yeung, B.K.S.3
-
4
-
-
77952704258
-
Thousands of chemical starting points for antimalarial lead identification
-
7296
-
Gamo FJ, Sanz LM, Vidal J et al. Thousands of chemical starting points for antimalarial lead identification. Nature 465(7296), 305-310 (2010).
-
(2010)
Nature
, vol.465
, pp. 305-310
-
-
Gamo, F.J.1
Sanz, L.M.2
Vidal, J.3
-
5
-
-
77952718950
-
Chemical genetics of plasmodium falciparum
-
7296
-
Guiguemde WA, Shelat AA, Bouck D et al. Chemical genetics of Plasmodium falciparum. Nature 465(7296), 311-315 (2010).
-
(2010)
Nature
, vol.465
, pp. 311-315
-
-
Guiguemde, W.A.1
Shelat, A.A.2
Bouck, D.3
-
6
-
-
70350778454
-
New medicines to improve control and contribute to the eradication of malaria
-
Wells TNC, Alonso PL, Gutteridge W. New medicines to improve control and contribute to the eradication of malaria. Nat. Rev. Drug Discov. 8(11), 879-891 (2009).
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, Issue.11
, pp. 879-891
-
-
Wells, T.N.C.1
Alonso, P.L.2
Gutteridge, W.3
-
7
-
-
64549087994
-
Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice
-
Gujjar R, Marwaha A, Mazouni FE et al. Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice. J. Med. Chem. 52(7), 1864-1872 (2009)
-
(2009)
J. Med. Chem.
, vol.52
, Issue.7
, pp. 1864-1872
-
-
Gujjar, R.1
Marwaha, A.2
Mazouni, F.E.3
-
8
-
-
45749119578
-
Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite plasmodium falciparum
-
Phillips MA, Gujjar R, Malmquist NA et al. Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum. J. Med. Chem. 51(12), 3649-3653 (2008).
-
(2008)
J. Med. Chem.
, vol.51
, Issue.12
, pp. 3649-3653
-
-
Phillips, M.A.1
Gujjar, R.2
Malmquist, N.A.3
-
9
-
-
20444470318
-
High-throughput screening for potent and selective inhibitors of plasmodium falciparum dihydroorotate dehydrogenase
-
Baldwin J, Michnoff CH, Malmquist NA et al. High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. J. Biol. Chem. 280(23), 21847-21853 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, Issue.23
, pp. 21847-21853
-
-
Baldwin, J.1
Michnoff, C.H.2
Malmquist, N.A.3
-
10
-
-
0037015614
-
Genome sequence of the human malaria parasite plasmodium falciparum
-
6906
-
Gardner MJ, Hall N, Fung E et al. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419(6906), 498-511 (2002).
-
(2002)
Nature
, vol.419
, pp. 498-511
-
-
Gardner, M.J.1
Hall, N.2
Fung, E.3
-
11
-
-
77950637685
-
Inhibitors of the mitochondrial electron transport chain and de novo pyrimidine biosynthesis as antimalarials: The present status
-
Rodrigues T, Lopes F, Moreira R. Inhibitors of the mitochondrial electron transport chain and de novo pyrimidine biosynthesis as antimalarials: the present status. Curr. Med. Chem. 17(10), 929-956 (2010).
-
(2010)
Curr. Med. Chem.
, vol.17
, Issue.10
, pp. 929-956
-
-
Rodrigues, T.1
Lopes, F.2
Moreira, R.3
-
12
-
-
33750140518
-
The silent path to thousands of merozoites: The plasmodium liver stage
-
Prudêncio M, Rodriguez A, Mota MM. The silent path to thousands of merozoites: the Plasmodium liver stage. Nat. Rev. Microbiol. 4(11), 849-856 (2006).
-
(2006)
Nat. Rev. Microbiol.
, vol.4
, Issue.11
, pp. 849-856
-
-
Prudêncio, M.1
Rodriguez, A.2
Mota, M.M.3
-
13
-
-
85047689053
-
Antimalarial drugs-host targets re visited
-
Cunha-Rodrigues M, Prudêncio M, Mota MM, Haas W. Antimalarial drugs-host targets (re)visited. Biotechnol. J. 1(3), 321-332 (2006).
-
(2006)
Biotechnol. J.
, vol.1
, Issue.3
, pp. 321-332
-
-
Cunha-Rodrigues, M.1
Prudêncio, M.2
Mota, M.M.3
Haas, W.4
-
14
-
-
42049098407
-
New active drugs against liver stages of plasmodium predicted by molecular topology
-
Mahmoudi N, Garcia-Domenech R, Galvez J et al. New active drugs against liver stages of plasmodium predicted by molecular topology. Antimicrob. Agents Chemother. 52(4), 1215-1220 (2008).
-
(2008)
Antimicrob. Agents Chemother
, vol.52
, Issue.4
, pp. 1215-1220
-
-
Mahmoudi, N.1
Garcia-Domenech, R.2
Galvez, J.3
-
15
-
-
67650520138
-
Host cell transcriptional profiling during malaria liver stage infection reveals a coordinated and sequential set of biological events
-
Albuquerque SS, Carret C, Grosso AR et al. Host cell transcriptional profiling during malaria liver stage infection reveals a coordinated and sequential set of biological events. BMC Genomics 10, 270 (2009).
-
(2009)
BMC Genomics
, vol.10
, pp. 270
-
-
Albuquerque, S.S.1
Carret, C.2
Grosso, A.R.3
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