Thousands of chemical starting points for antimalarial lead identification

Nature

Volumn 465, Issue 7296, 2010, Pages 305-310

  Gamo, Francisco Javier ^a   Sanz, Laura M ^a   Vidal, Jaume ^a   De Cozar, Cristina ^a   Alvarez, Emilio ^a   Lavandera, Jose Luis ^a   Vanderwall, Dana E ^b   Green, Darren V S ^c   Kumar, Vinod ^b   Hasan, Samiul ^b   Brown, James R ^b   Peishoff, Catherine E ^b   Cardon, Lon R ^b   Garcia Bustos, Jose F ^a  

^a GLAXOSMITHKLINE   (Spain)

^b GLAXOSMITHKLINE   (United States)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT; ARTEMISININ; ATOVAQUONE; CHLOROQUINE; CYCLOGUANIL; G PROTEIN COUPLED RECEPTOR; PRIMAQUINE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PYRIMETHAMINE; QUININE; TETRACYCLINE DERIVATIVE;

ANTIMALARIAL AGENT; DISEASE CONTROL; DRUG DEVELOPMENT; DRUG RESISTANCE; ENZYME ACTIVITY; HOST-PARASITE INTERACTION; MALARIA; MEDICINE; PROTOZOAN; RESEARCH WORK;

ANALYSIS; ANTIMALARIAL ACTIVITY; ARTICLE; ASSAY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SCREENING; GROWTH INHIBITION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; MALARIA; MICROBIAL COMMUNITY; MICROBIAL GROWTH; MOLECULAR LIBRARY; MULTIDRUG RESISTANCE; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 77952704258     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09107     Document Type: Article

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