Efficacy and safety of atovaquone/proguanil as suppressive prophylaxis for Plasmodium falciparum malaria

Clinical Infectious Diseases

Volumn 27, Issue 3, 1998, Pages 494-499

  Shanks, G Dennis ^b   Gordon, Daniel M ^b   Klotz, Francis W ^b   Aleman, Gladys M ^b   Oloo, Aggrey J ^b   Sadie, Deborah ^b   Scott, Trevor R ^a  

^a GLAXOSMITHKLINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ATOVAQUONE; PROGUANIL;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DYSPEPSIA; ENDEMIC DISEASE; FEMALE; GASTRITIS; HUMAN; HUMAN EXPERIMENT; KENYA; MALARIA CONTROL; MALARIA FALCIPARUM; MALE; NORMAL HUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

EID: 0031666231     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/514710     Document Type: Article

References (10)

1. Krogstad DJ. Malaria as a reemerging disease. Epidemiol Rev 1996;18: 77-89.
2. World Health Organization. Practical chemotherapy of malaria. World Health Organ Tech Rep Ser 1990;805:1-141.
3. Anonymous. Towards a malarial vaccine [editorial]. Lancet 1992;339: 586-7.
4. Hoffman SL. Diagnosis, treatment, and prevention of malaria. Med Clin North Am 1992;76:1327-55.
5. Centers for Disease Control. Revised dosing regimen for malaria prophylaxis with mefloquine. MMWR Morb Mortal Wkly Rep 1990;39:630.
6. Bern JL, Kerr L, Stuerchler D. Mefloquine prophylaxis: an overview of spontaneous reports of severe psychiatric reactions and convulsions. J Trop Med Hyg 1992;95:167-79.
7. Weinke T, Trautmann M, Held T, et al. Neuropsychiatrie side effects after the use of mefloquine. Am J Trop Med Hyg 1991;45:86-91.
8. Henderson A, Simon JW, Melia W. Failure of malaria chemoprophylaxis with a proguanil-chloroquine combination in Papua New Guinea. Trans R Soc Trop Med Hyg 1986;80:838-40.
9. Palmer KJ, Holliday SM, Brogden RN. Mefloquine: a review of its antimalarial activity, pharmacokinetic properties and therapeutic efficacy. Drugs 1993;45:430-75.
10. Pudney M. Antimalarials: from quinine to atovaquone. In: Hunter PA, Darby GK, Russell NJ, eds. 50 Years of antimicrobials. Society for General Microbiology, symposium 53. Cambridge: Cambridge University Press, 1995:229-47.