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Volumn 82, Issue 10, 2011, Pages 1311-1319

Yellow submarine of the Wnt/Frizzled signaling: Submerging from the G protein harbor to the targets

Author keywords

Frizzled; GPCR; Heterotrimeric G protein; Rab5; Wnt

Indexed keywords

AXIN; FRIZZLED PROTEIN; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; MONOMER; RAB PROTEIN; WNT PROTEIN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND;

EID: 80054685356     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.06.005     Document Type: Conference Paper
Times cited : (60)

References (170)
  • 1
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • DOI 10.1146/annurev.cellbio.20.010403.113126
    • C.Y. Logan, and R. Nusse The Wnt signaling pathway in development and disease Annu Rev Cell Dev Biol 20 2004 781 810 (Pubitemid 39488658)
    • (2004) Annual Review of Cell and Developmental Biology , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 2
    • 60349105063 scopus 로고    scopus 로고
    • Tipping the balance: Modulating the Wnt pathway for tissue repair
    • J. Zhao, K.A. Kim, and A. Abo Tipping the balance: modulating the Wnt pathway for tissue repair Trends Biotechnol 27 2009 131 136
    • (2009) Trends Biotechnol , vol.27 , pp. 131-136
    • Zhao, J.1    Kim, K.A.2    Abo, A.3
  • 4
    • 33845350346 scopus 로고    scopus 로고
    • The ups and downs of Wnt signaling in prevalent neurological disorders
    • DOI 10.1038/sj.onc.1210064, PII 1210064
    • G.V. De Ferrari, and R.T. Moon The ups and downs of Wnt signaling in prevalent neurological disorders Oncogene 25 2006 7545 7553 (Pubitemid 44885754)
    • (2006) Oncogene , vol.25 , Issue.57 , pp. 7545-7553
    • De Ferrari, G.V.1    Moon, R.T.2
  • 6
    • 33751530490 scopus 로고    scopus 로고
    • Mining the Wnt pathway for cancer therapeutics
    • DOI 10.1038/nrd2154, PII NRD2154
    • N. Barker, and H. Clevers Mining the Wnt pathway for cancer therapeutics Nat Rev Drug Discov 5 2006 997 1014 (Pubitemid 44835127)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.12 , pp. 997-1014
    • Barker, N.1    Clevers, H.2
  • 7
    • 0036111153 scopus 로고    scopus 로고
    • Planar signaling and morphogenesis in Drosophila
    • DOI 10.1016/S1534-5807(02)00176-4
    • P.N. Adler Planar signaling and morphogenesis in Drosophila Dev Cell 2 2002 525 535 (Pubitemid 34538134)
    • (2002) Developmental Cell , vol.2 , Issue.5 , pp. 525-535
    • Adler, P.N.1
  • 8
    • 0029994517 scopus 로고    scopus 로고
    • A new member of the Frizzled family from Drosophila functions as a Wingless receptor
    • P. Bhanot, M. Brink, C.H. Samos, J.C. Hsieh, Y. Wang, and J.P. Macke A new member of the Frizzled family from Drosophila functions as a Wingless receptor Nature 382 1996 225 230
    • (1996) Nature , vol.382 , pp. 225-230
    • Bhanot, P.1    Brink, M.2    Samos, C.H.3    Hsieh, J.C.4    Wang, Y.5    MacKe, J.P.6
  • 9
    • 0024972122 scopus 로고
    • A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains
    • C.R. Vinson, S. Conover, and P.N. Adler A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains Nature 338 1989 263 264
    • (1989) Nature , vol.338 , pp. 263-264
    • Vinson, C.R.1    Conover, S.2    Adler, P.N.3
  • 10
    • 0025016015 scopus 로고
    • Molecular structure of frizzled, a Drosophila tissue polarity gene
    • P.N. Adler, C. Vinson, W.J. Park, S. Conover, and L. Klein Molecular structure of Frizzled, a Drosophila tissue polarity gene Genetics 126 1990 401 416 (Pubitemid 20341022)
    • (1990) Genetics , vol.126 , Issue.2 , pp. 401-416
    • Adler, P.N.1    Vinson, C.2    Park, W.J.3    Conover, S.4    Klein, L.5
  • 11
    • 0016688080 scopus 로고
    • Molecular structure determination by electron microscopy of unstained crystalline specimens
    • P.N. Unwin, and R. Henderson Molecular structure determination by electron microscopy of unstained crystalline specimens J Mol Biol 94 1975 425 440
    • (1975) J Mol Biol , vol.94 , pp. 425-440
    • Unwin, P.N.1    Henderson, R.2
  • 14
    • 0022485749 scopus 로고
    • Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
    • R.A. Dixon, B.K. Kobilka, D.J. Strader, J.L. Benovic, H.G. Dohlman, and T. Frielle Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin Nature 321 1986 75 79 (Pubitemid 16080889)
    • (1986) Nature , vol.321 , Issue.6065 , pp. 75-79
    • Dixon, R.A.F.1    Kobilka, B.K.2    Strader, D.J.3
  • 15
    • 73549104285 scopus 로고    scopus 로고
    • The year in G protein-coupled receptor research
    • R.P. Millar, and C.L. Newton The year in G protein-coupled receptor research Mol Endocrinol 24 2010 261 274
    • (2010) Mol Endocrinol , vol.24 , pp. 261-274
    • Millar, R.P.1    Newton, C.L.2
  • 17
    • 0043235844 scopus 로고    scopus 로고
    • Ligand-selective receptor conformations revisited: The promise and the problem
    • DOI 10.1016/S0165-6147(03)00167-6
    • T. Kenakin Ligand-selective receptor conformations revisited: the promise and the problem Trends Pharmacol Sci 24 2003 346 354 (Pubitemid 37315526)
    • (2003) Trends in Pharmacological Sciences , vol.24 , Issue.7 , pp. 346-354
    • Kenakin, T.1
  • 19
    • 78650926798 scopus 로고    scopus 로고
    • Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis
    • B.K. Atwood, J. Lopez, J. Wager-Miller, K. Mackie, and A. Straiker Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis BMC Genomics 12 2011 14
    • (2011) BMC Genomics , vol.12 , pp. 14
    • Atwood, B.K.1    Lopez, J.2    Wager-Miller, J.3    MacKie, K.4    Straiker, A.5
  • 20
    • 0025729647 scopus 로고
    • The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation
    • M. Peifer, C. Rauskolb, M. Williams, B. Riggleman, and E. Wieschaus The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation Development 111 1991 1029 1043 (Pubitemid 21900258)
    • (1991) Development , vol.111 , Issue.4 , pp. 1029-1043
    • Peifer, M.1    Rauskolb, C.2    Williams, M.3    Riggleman, B.4    Wieschaus, E.5
  • 21
    • 0027954477 scopus 로고
    • The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal
    • J. Klingensmith, R. Nusse, and N. Perrimon The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal Genes Dev 8 1994 118 130 (Pubitemid 24032858)
    • (1994) Genes and Development , vol.8 , Issue.1 , pp. 118-130
    • Klingensmith, J.1    Nusse, R.2    Perrimon, N.3
  • 22
    • 0029920839 scopus 로고    scopus 로고
    • Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes
    • J. Papkoff, B. Rubinfeld, B. Schryver, and P. Polakis Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes Mol Cell Biol 16 1996 2128 2134 (Pubitemid 26123733)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.5 , pp. 2128-2134
    • Papkoff, J.1    Rubinfeld, B.2    Schryver, B.3    Polakis, P.4
  • 23
    • 0031456672 scopus 로고    scopus 로고
    • Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling
    • DOI 10.1038/37138
    • D.C. Slusarski, V.G. Corces, and R.T. Moon Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling Nature 390 1997 410 413 (Pubitemid 28027323)
    • (1997) Nature , vol.390 , Issue.6658 , pp. 410-413
    • Slusarski, D.C.1    Corces, V.G.2    Moon, R.T.3
  • 24
    • 11844299003 scopus 로고    scopus 로고
    • Trimeric G protein-dependent frizzled signaling in Drosophila
    • DOI 10.1016/j.cell.2004.11.014, PII S0092867404010876
    • V.L. Katanaev, R. Ponzielli, M. Semeriva, and A. Tomlinson Trimeric G protein-dependent Frizzled signaling in Drosophila Cell 120 2005 111 122 (Pubitemid 40094607)
    • (2005) Cell , vol.120 , Issue.1 , pp. 111-122
    • Katanaev, V.L.1    Ponzielli, R.2    Semeriva, M.3    Tomlinson, A.4
  • 25
    • 33646264327 scopus 로고    scopus 로고
    • Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila
    • V.L. Katanaev, and A. Tomlinson Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila Proc Natl Acad Sci USA 103 2006 6524 6529
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6524-6529
    • Katanaev, V.L.1    Tomlinson, A.2
  • 26
    • 33751236172 scopus 로고    scopus 로고
    • Multiple roles of a trimeric G protein in Drosophila cell polarization
    • V.L. Katanaev, and A. Tomlinson Multiple roles of a trimeric G protein in Drosophila cell polarization Cell Cycle 5 2006 2464 2472 (Pubitemid 44785823)
    • (2006) Cell Cycle , vol.5 , Issue.21 , pp. 2464-2472
    • Katanaev, V.L.1    Tomlinson, A.2
  • 30
    • 0035368394 scopus 로고    scopus 로고
    • G protein signaling from activated rat Frizzled-1 to the β-catenin-lef-tcf pathway
    • DOI 10.1126/science.1060100
    • T. Liu, A.J. DeCostanzo, X. Liu, H. Wang, S. Hallagan, and R.T. Moon G protein signaling from activated rat Frizzled-1 to the beta-catenin-Lef-Tcf pathway Science 292 2001 1718 1722 (Pubitemid 32506245)
    • (2001) Science , vol.292 , Issue.5522 , pp. 1718-1722
    • Liu, T.1    DeCostanzo, A.J.2    Liu, X.3    Wang, H.4    Hallagan, S.5    Moon, R.T.6    Malbon, C.C.7
  • 31
    • 27844516613 scopus 로고    scopus 로고
    • Rapid, Wnt-induced changes in GSK3β associations that regulate β-catenin stabilization are mediated by Gα proteins
    • DOI 10.1016/j.cub.2005.10.050, PII S0960982205013035
    • X. Liu, J.S. Rubin, and A.R. Kimmel Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins Curr Biol 15 2005 1989 1997 (Pubitemid 41654621)
    • (2005) Current Biology , vol.15 , Issue.22 , pp. 1989-1997
    • Liu, X.1    Rubin, J.S.2    Kimmel, A.R.3
  • 32
    • 39049142759 scopus 로고    scopus 로고
    • o mediates WNT-JNK signaling through dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells
    • DOI 10.1242/jcs.021964
    • R.K. Bikkavilli, M.E. Feigin, and C.C. Malbon G{alpha}o mediates WNT-JNK signaling through Dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells J Cell Sci 121 2008 234 245 (Pubitemid 351232664)
    • (2008) Journal of Cell Science , vol.121 , Issue.2 , pp. 234-245
    • Bikkavilli, R.K.1    Feigin, M.E.2    Malbon, C.C.3
  • 33
    • 70349355268 scopus 로고    scopus 로고
    • Frizzled proteins are bonafide G protein-coupled receptors
    • Katanaev VL, Buestorf S. Frizzled proteins are bonafide G protein-coupled receptors. Available from Nature Precedings: http://hdlhandlenet/10101/ npre200927651; 2009.
    • (2009) Nature Precedings
    • Katanaev, V.L.1    Buestorf, S.2
  • 34
    • 78751483422 scopus 로고    scopus 로고
    • Wnt3a stimulation elicits G-protein-coupled receptor properties of mammalian Frizzled proteins
    • A. Koval, and V.L. Katanaev Wnt3a stimulation elicits G-protein-coupled receptor properties of mammalian Frizzled proteins Biochem J 433 2011 435 440
    • (2011) Biochem J , vol.433 , pp. 435-440
    • Koval, A.1    Katanaev, V.L.2
  • 35
    • 78650414896 scopus 로고    scopus 로고
    • WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive heterotrimeric G proteins
    • M.B. Kilander, J.P. Dijksterhuis, R.S. Ganji, V. Bryja, and G. Schulte WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive heterotrimeric G proteins Cell Signal 23 2011 550 554
    • (2011) Cell Signal , vol.23 , pp. 550-554
    • Kilander, M.B.1    Dijksterhuis, J.P.2    Ganji, R.S.3    Bryja, V.4    Schulte, G.5
  • 36
    • 78751559473 scopus 로고    scopus 로고
    • Wnt signalling: The case of the 'missing' G-protein
    • C.C. Malbon Wnt signalling: the case of the 'missing' G-protein Biochem J 433 2011 e3 5
    • (2011) Biochem J , vol.433 , pp. 3-5
    • Malbon, C.C.1
  • 37
    • 42549114740 scopus 로고    scopus 로고
    • Trimeric G protein-dependent signaling by Frizzled receptors in animal development
    • DOI 10.2741/3036
    • D. Egger-Adam, and V.L. Katanaev Trimeric G protein-dependent signaling by Frizzled receptors in animal development Front Biosci 13 2008 4740 4755 (Pubitemid 351589194)
    • (2008) Frontiers in Bioscience , vol.13 , Issue.12 , pp. 4740-4755
    • Egger-Adam, D.1    Katanaev, V.L.2
  • 38
    • 79251577991 scopus 로고    scopus 로고
    • The Wnt/frizzled GPCR signaling pathway
    • V.L. Katanaev The Wnt/frizzled GPCR signaling pathway Biochemistry (Mosc) 75 2010 1428 1434
    • (2010) Biochemistry (Mosc) , vol.75 , pp. 1428-1434
    • Katanaev, V.L.1
  • 39
    • 33645096878 scopus 로고    scopus 로고
    • Structure-function analysis of Frizzleds
    • H.Y. Wang, T. Liu, and C.C. Malbon Structure-function analysis of Frizzleds Cell Signal 18 2006 934 941
    • (2006) Cell Signal , vol.18 , pp. 934-941
    • Wang, H.Y.1    Liu, T.2    Malbon, C.C.3
  • 40
    • 0032482447 scopus 로고    scopus 로고
    • The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases
    • Y.K. Xu, and R. Nusse The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases Curr Biol 8 1998 R405 R406
    • (1998) Curr Biol , vol.8
    • Xu, Y.K.1    Nusse, R.2
  • 41
    • 0033636247 scopus 로고    scopus 로고
    • Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless
    • E.J. Rulifson, C.H. Wu, and R. Nusse Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless Mol Cell 6 2000 117 126
    • (2000) Mol Cell , vol.6 , pp. 117-126
    • Rulifson, E.J.1    Wu, C.H.2    Nusse, R.3
  • 42
    • 0036830126 scopus 로고    scopus 로고
    • Ligand receptor interactions in the Wnt signaling pathway in Drosophila
    • DOI 10.1074/jbc.M207850200
    • C.H. Wu, and R. Nusse Ligand receptor interactions in the Wnt signaling pathway in Drosophila J Biol Chem 277 2002 41762 41769 (Pubitemid 35257485)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.44 , pp. 41762-41769
    • Wu, C.-H.1    Nusse, R.2
  • 43
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signalling pathway
    • DOI 10.1242/jcs.00623
    • Y. Kawano, and R. Kypta Secreted antagonists of the Wnt signalling pathway J Cell Sci 116 2003 2627 2634 (Pubitemid 36857216)
    • (2003) Journal of Cell Science , vol.116 , Issue.13 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 44
    • 0030602796 scopus 로고    scopus 로고
    • The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal
    • DOI 10.1016/S0092-8674(00)80094-X
    • J. Alcedo, M. Ayzenzon, T. Von Ohlen, M. Noll, and J.E. Hooper The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal Cell 86 1996 221 232 (Pubitemid 26286105)
    • (1996) Cell , vol.86 , Issue.2 , pp. 221-232
    • Alcedo, J.1    Ayzenzon, M.2    Von Ohlen, T.3    Noll, M.4    Hooper, J.E.5
  • 46
    • 0035297563 scopus 로고    scopus 로고
    • Signal transduction in neutrophil chemotaxis
    • DOI 10.1023/A:1010293809553
    • V.L. Katanaev Signal transduction in neutrophil chemotaxis Biochemistry (Mosc) 66 2001 351 368 (Pubitemid 32617176)
    • (2001) Biochemistry (Moscow) , vol.66 , Issue.4 , pp. 351-368
    • Katanaev, V.L.1
  • 47
    • 55749102279 scopus 로고    scopus 로고
    • Alternative wnt signaling is initiated by distinct receptors
    • R. van Amerongen, A. Mikels, and R. Nusse Alternative wnt signaling is initiated by distinct receptors Sci Signal 1 2008 re9
    • (2008) Sci Signal , vol.1 , pp. 9
    • Van Amerongen, R.1    Mikels, A.2    Nusse, R.3
  • 48
    • 70349932747 scopus 로고    scopus 로고
    • Towards an integrated view of Wnt signaling in development
    • R. van Amerongen, and R. Nusse Towards an integrated view of Wnt signaling in development Development 136 2009 3205 3214
    • (2009) Development , vol.136 , pp. 3205-3214
    • Van Amerongen, R.1    Nusse, R.2
  • 49
    • 72049122388 scopus 로고    scopus 로고
    • Europium-labeled GTP as a general nonradioactive substitute for [(35)S]GTPgammaS in high-throughput G protein studies
    • A. Koval, D. Kopein, V. Purvanov, and V.L. Katanaev Europium-labeled GTP as a general nonradioactive substitute for [(35)S]GTPgammaS in high-throughput G protein studies Anal Biochem 397 2010 202 207
    • (2010) Anal Biochem , vol.397 , pp. 202-207
    • Koval, A.1    Kopein, D.2    Purvanov, V.3    Katanaev, V.L.4
  • 50
    • 84864388381 scopus 로고    scopus 로고
    • Assay for monitoring activity of frizzled receptors
    • Katanaev VL. Assay for monitoring activity of frizzled receptors. Eur Pat Appl, EP2048503, 2009.
    • (2009) Eur Pat Appl, EP2048503
    • Katanaev, V.L.1
  • 51
    • 78349276165 scopus 로고    scopus 로고
    • Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors
    • L. Grumolato, G. Liu, P. Mong, R. Mudbhary, R. Biswas, and R. Arroyave Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors Genes Dev 24 2010 2517 2530
    • (2010) Genes Dev , vol.24 , pp. 2517-2530
    • Grumolato, L.1    Liu, G.2    Mong, P.3    Mudbhary, R.4    Biswas, R.5    Arroyave, R.6
  • 53
    • 79952764368 scopus 로고    scopus 로고
    • LRP6 mediates cAMP generation by G protein-coupled receptors through regulating the membrane targeting of Galpha(s)
    • M. Wan, J. Li, K. Herbst, J. Zhang, B. Yu, and X. Wu LRP6 mediates cAMP generation by G protein-coupled receptors through regulating the membrane targeting of Galpha(s) Sci Signal 4 2011 ra15
    • (2011) Sci Signal , vol.4 , pp. 15
    • Wan, M.1    Li, J.2    Herbst, K.3    Zhang, J.4    Yu, B.5    Wu, X.6
  • 54
    • 55749091843 scopus 로고    scopus 로고
    • Parathyroid hormone signaling through low-density lipoprotein-related protein 6
    • M. Wan, C. Yang, J. Li, X. Wu, H. Yuan, and H. Ma Parathyroid hormone signaling through low-density lipoprotein-related protein 6 Genes Dev 22 2008 2968 2979
    • (2008) Genes Dev , vol.22 , pp. 2968-2979
    • Wan, M.1    Yang, C.2    Li, J.3    Wu, X.4    Yuan, H.5    Ma, H.6
  • 55
    • 33750307507 scopus 로고    scopus 로고
    • RAMPs: The past, present and future
    • DOI 10.1016/j.tibs.2006.09.006, PII S0968000406002416
    • N. Parameswaran, and W.S. Spielman RAMPs: the past, present and future Trends Biochem Sci 31 2006 631 638 (Pubitemid 44635265)
    • (2006) Trends in Biochemical Sciences , vol.31 , Issue.11 , pp. 631-638
    • Parameswaran, N.1    Spielman, W.S.2
  • 56
    • 35548983852 scopus 로고    scopus 로고
    • Lipoproteins and their receptors in embryonic development: More than cholesterol clearance
    • DOI 10.1242/dev.004408
    • T.E. Willnow, A. Hammes, and S. Eaton Lipoproteins and their receptors in embryonic development: more than cholesterol clearance Development 134 2007 3239 3249 (Pubitemid 350018425)
    • (2007) Development , vol.134 , Issue.18 , pp. 3239-3249
    • Willnow, T.E.1    Hammes, A.2    Eaton, S.3
  • 57
    • 18344378499 scopus 로고    scopus 로고
    • Lipoprotein particles are required for Hedgehog and Wingless signalling
    • DOI 10.1038/nature03504
    • D. Panakova, H. Sprong, E. Marois, C. Thiele, and S. Eaton Lipoprotein particles are required for Hedgehog and Wingless signalling Nature 435 2005 58 65 (Pubitemid 40655904)
    • (2005) Nature , vol.435 , Issue.7038 , pp. 58-65
    • Panakova, D.1    Sprong, H.2    Marois, E.3    Thiele, C.4    Eaton, S.5
  • 58
    • 38949159320 scopus 로고    scopus 로고
    • Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila
    • DOI 10.1038/sj.emboj.7601981, PII 7601981
    • V.L. Katanaev, G.P. Solis, G. Hausmann, S. Buestorf, N. Katanayeva, and Y. Schrock Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila EMBO J 27 2008 509 521 (Pubitemid 351225681)
    • (2008) EMBO Journal , vol.27 , Issue.3 , pp. 509-521
    • Katanaev, V.L.1    Solis, G.P.2    Hausmann, G.3    Buestorf, S.4    Katanayeva, N.5    Schrock, Y.6    Stuermer, C.A.7    Basler, K.8
  • 59
    • 30644469247 scopus 로고    scopus 로고
    • Release and trafficking of lipid-linked morphogens
    • DOI 10.1016/j.gde.2005.12.006, PII S0959437X05002194, Oncogenes and Cell Proliferation
    • S. Eaton Release and trafficking of lipid-linked morphogens Curr Opin Genet Dev 16 2006 17 22 (Pubitemid 43089607)
    • (2006) Current Opinion in Genetics and Development , vol.16 , Issue.1 , pp. 17-22
    • Eaton, S.1
  • 61
    • 80054700840 scopus 로고    scopus 로고
    • The making of Wnt: New insights into Wnt maturation, sorting and secretion
    • D. Coudreuse, and H.C. Korswagen The making of Wnt: new insights into Wnt maturation, sorting and secretion Development 2006
    • (2006) Development
    • Coudreuse, D.1    Korswagen, H.C.2
  • 62
    • 77956495200 scopus 로고    scopus 로고
    • Wnt trafficking: New insights into Wnt maturation, secretion and spreading
    • F. Port, and K. Basler Wnt trafficking: new insights into Wnt maturation, secretion and spreading Traffic 11 2010 1265 1271
    • (2010) Traffic , vol.11 , pp. 1265-1271
    • Port, F.1    Basler, K.2
  • 64
    • 73949113486 scopus 로고    scopus 로고
    • The trimeric G protein Go inflicts a double impact on axin in the Wnt/frizzled signaling pathway
    • D. Egger-Adam, and V.L. Katanaev The trimeric G protein Go inflicts a double impact on axin in the Wnt/frizzled signaling pathway Dev Dyn 239 2010 168 183
    • (2010) Dev Dyn , vol.239 , pp. 168-183
    • Egger-Adam, D.1    Katanaev, V.L.2
  • 65
    • 77956642982 scopus 로고    scopus 로고
    • A direct and functional interaction between Go and Rab5 during G protein-coupled receptor signaling
    • V. Purvanov, A. Koval, and V.L. Katanaev A direct and functional interaction between Go and Rab5 during G protein-coupled receptor signaling Sci Signal 3 2010 ra65
    • (2010) Sci Signal , vol.3 , pp. 65
    • Purvanov, V.1    Koval, A.2    Katanaev, V.L.3
  • 67
    • 0035811492 scopus 로고    scopus 로고
    • Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
    • DOI 10.1038/35083601
    • C.E. Dann, J.C. Hsieh, A. Rattner, D. Sharma, J. Nathans, and D.J. Leahy Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains Nature 412 2001 86 90 (Pubitemid 32851515)
    • (2001) Nature , vol.412 , Issue.6842 , pp. 86-90
    • Dann, C.E.1    Hsieh, J.-C.2    Rattner, A.3    Sharma, D.4    Nathans, J.5    Leahy, D.J.6
  • 68
    • 0038497887 scopus 로고    scopus 로고
    • Frizzled receptor dimerization is sufficient to activate the Wnt/β-catenin pathway
    • DOI 10.1242/jcs.00451
    • C. Carron, A. Pascal, A. Djiane, J.C. Boucaut, D.L. Shi, and M. Umbhauer Frizzled receptor dimerization is sufficient to activate the Wnt/beta-catenin pathway J Cell Sci 116 2003 2541 2550 (Pubitemid 36790135)
    • (2003) Journal of Cell Science , vol.116 , Issue.12 , pp. 2541-2550
    • Carron, C.1    Pascal, A.2    Djiane, A.3    Boucaut, J.-C.4    Shi, D.-L.5    Umbhauer, M.6
  • 69
    • 1342332090 scopus 로고    scopus 로고
    • Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization
    • DOI 10.1038/ncb1081
    • A. Kaykas, J. Yang-Snyder, M. Heroux, K.V. Shah, M. Bouvier, and R.T. Moon Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization Nat Cell Biol 6 2004 52 58 (Pubitemid 38425730)
    • (2004) Nature Cell Biology , vol.6 , Issue.1 , pp. 52-58
    • Kaykas, A.1    Yang-Snyder, J.2    Heroux, M.3    Shah, K.V.4    Bouvier, M.5    Moon, R.T.6
  • 70
    • 3042798261 scopus 로고    scopus 로고
    • Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: Molecular modeling and mutagenesis approaches to receptor structure and function
    • DOI 10.1016/j.pharmthera.2004.05.002, PII S0163725804000695
    • K. Kristiansen Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function Pharmacol Ther 103 2004 21 80 (Pubitemid 38891912)
    • (2004) Pharmacology and Therapeutics , vol.103 , Issue.1 , pp. 21-80
    • Kristiansen, K.1
  • 71
    • 0036780743 scopus 로고    scopus 로고
    • G-protein-coupled receptor oligomerization and its potential for drug discovery
    • DOI 10.1038/nrd913
    • S.R. George, B.F. O'Dowd, and S.P. Lee G-protein-coupled receptor oligomerization and its potential for drug discovery Nat Rev Drug Discov 1 2002 808 820 (Pubitemid 37361564)
    • (2002) Nature Reviews Drug Discovery , vol.1 , Issue.10 , pp. 808-820
    • George, S.R.1    O'Dowd, B.F.2    Lee, S.P.3
  • 72
    • 0034665045 scopus 로고    scopus 로고
    • The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling
    • M. Umbhauer, A. Djiane, C. Goisset, A. Penzo-Mendez, J.F. Riou, and J.C. Boucaut The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling EMBO J 19 2000 4944 4954
    • (2000) EMBO J , vol.19 , pp. 4944-4954
    • Umbhauer, M.1    Djiane, A.2    Goisset, C.3    Penzo-Mendez, A.4    Riou, J.F.5    Boucaut, J.C.6
  • 73
    • 68849124264 scopus 로고    scopus 로고
    • Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins
    • C. Punchihewa, A.M. Ferreira, R. Cassell, P. Rodrigues, and N. Fujii Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins Protein Sci 18 2009 994 1002
    • (2009) Protein Sci , vol.18 , pp. 994-1002
    • Punchihewa, C.1    Ferreira, A.M.2    Cassell, R.3    Rodrigues, P.4    Fujii, N.5
  • 74
    • 33645888429 scopus 로고    scopus 로고
    • Dishevelled: A mobile scaffold catalyzing development
    • C.C. Malbon, and H.Y. Wang Dishevelled: a mobile scaffold catalyzing development Curr Top Dev Biol 72 2006 153 166
    • (2006) Curr Top Dev Biol , vol.72 , pp. 153-166
    • Malbon, C.C.1    Wang, H.Y.2
  • 75
    • 77951888466 scopus 로고    scopus 로고
    • Dishevelled: The hub of Wnt signaling
    • C. Gao, and Y.G. Chen Dishevelled: the hub of Wnt signaling Cell Signal 22 2010 717 727
    • (2010) Cell Signal , vol.22 , pp. 717-727
    • Gao, C.1    Chen, Y.G.2
  • 76
    • 0033011602 scopus 로고    scopus 로고
    • DIX domains of DVl and Axin are necessary for protein interactions and their ability to regulate β-catenin stability
    • S. Kishida, H. Yamamoto, S. Hino, S. Ikeda, M. Kishida, and A. Kikuchi DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability Mol Cell Biol 19 1999 4414 4422 (Pubitemid 29242015)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.6 , pp. 4414-4422
    • Kishida, S.1    Yamamoto, H.2    Hino, S.-I.3    Ikeda, S.4    Kishida, M.5    Kikuchi, A.6
  • 77
    • 0033577808 scopus 로고    scopus 로고
    • Domains of Axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization
    • DOI 10.1083/jcb.145.4.741
    • F. Fagotto, E. Jho, L. Zeng, T. Kurth, T. Joos, and C. Kaufmann Domains of axin involved in protein-protein interactions. Wnt pathway inhibition, and intracellular localization J Cell Biol 145 1999 741 756 (Pubitemid 29240852)
    • (1999) Journal of Cell Biology , vol.145 , Issue.4 , pp. 741-756
    • Fagotto, F.1    Jho, E.-H.2    Zeng, L.3    Kurth, T.4    Joos, T.5    Kaufmann, C.6    Costantini, F.7
  • 78
    • 0037513408 scopus 로고    scopus 로고
    • A role of dishevelled in relocating axin to the plasma membrane during wingless signaling
    • DOI 10.1016/S0960-9822(03)00370-1
    • A. Cliffe, F. Hamada, and M. Bienz A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling Curr Biol 13 2003 960 966 (Pubitemid 36632146)
    • (2003) Current Biology , vol.13 , Issue.11 , pp. 960-966
    • Cliffe, A.1    Hamada, F.2    Bienz, M.3
  • 79
    • 34547750005 scopus 로고    scopus 로고
    • Dynamic recruitment of axin by Dishevelled protein assemblies
    • DOI 10.1242/jcs.002956
    • T. Schwarz-Romond, C. Metcalfe, and M. Bienz Dynamic recruitment of axin by Dishevelled protein assemblies J Cell Sci 120 2007 2402 2412 (Pubitemid 47225943)
    • (2007) Journal of Cell Science , vol.120 , Issue.14 , pp. 2402-2412
    • Schwarz-Romond, T.1    Metcalfe, C.2    Bienz, M.3
  • 80
    • 0035873390 scopus 로고    scopus 로고
    • Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling
    • J.D. Axelrod Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling Genes Dev 15 2001 1182 1187 (Pubitemid 32472747)
    • (2001) Genes and Development , vol.15 , Issue.10 , pp. 1182-1187
    • Axelrod, J.D.1
  • 81
    • 31744436549 scopus 로고    scopus 로고
    • Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium
    • DOI 10.1016/j.devcel.2005.11.016, PII S1534580705004764
    • Y. Shimada, S. Yonemura, H. Ohkura, D. Strutt, and T. Uemura Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium Dev Cell 10 2006 209 222 (Pubitemid 43174954)
    • (2006) Developmental Cell , vol.10 , Issue.2 , pp. 209-222
    • Shimada, Y.1    Yonemura, S.2    Ohkura, H.3    Strutt, D.4    Uemura, T.5
  • 82
    • 0034772624 scopus 로고    scopus 로고
    • Kermit, a frizzled interacting protein, regulates frizzled signaling in neural crest development
    • C. Tan, M.A. Deardorff, J.P. Saint-Jeannet, J. Yang, A. Arzoumanian, and P.S. Klein Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest development Development 128 2001 3665 3674 (Pubitemid 32998916)
    • (2001) Development , vol.128 , Issue.19 , pp. 3665-3674
    • Tan, C.1    Deardorff, M.A.2    Saint-Jeannet, J.-P.3    Yang, J.4    Arzoumanian, A.5    Klein, P.S.6
  • 84
    • 0034812092 scopus 로고    scopus 로고
    • Identification of a PDZ domain containing golgi protein, GOPC, as an interaction partner of frizzled
    • DOI 10.1006/bbrc.2001.5430
    • R. Yao, T. Maeda, S. Takada, and T. Noda Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled Biochem Biophys Res Commun 286 2001 771 778 (Pubitemid 32912954)
    • (2001) Biochemical and Biophysical Research Communications , vol.286 , Issue.4 , pp. 771-778
    • Yao, R.1    Maeda, T.2    Takada, S.3    Noda, T.4
  • 85
    • 35648944705 scopus 로고    scopus 로고
    • o
    • DOI 10.1242/jcs.011254
    • M.E. Feigin, and C.C. Malbon RGS19 regulates Wnt-beta-catenin signaling through inactivation of Galpha(o) J Cell Sci 120 2007 3404 3414 (Pubitemid 350028348)
    • (2007) Journal of Cell Science , vol.120 , Issue.19 , pp. 3404-3414
    • Feigin, M.E.1    Malbon, C.C.2
  • 87
    • 0034806856 scopus 로고    scopus 로고
    • Pist: A novel pdz/coiled-coil domain binding partner for the rho-family gtpase tc10
    • DOI 10.1006/bbrc.2000.4160
    • C.L. Neudauer, G. Joberty, and I.G. Macara PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10 Biochem Biophys Res Commun 280 2001 541 547 (Pubitemid 32912825)
    • (2001) Biochemical and Biophysical Research Communications , vol.280 , Issue.2 , pp. 541-547
    • Neudauer, C.L.1    Joberty, G.2    Macara, I.G.3
  • 92
    • 71749094586 scopus 로고    scopus 로고
    • G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway
    • M. Chen, M. Philipp, J. Wang, R.T. Premont, T.R. Garrison, and M.G. Caron G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway J Biol Chem 284 2009 35040 35048
    • (2009) J Biol Chem , vol.284 , pp. 35040-35048
    • Chen, M.1    Philipp, M.2    Wang, J.3    Premont, R.T.4    Garrison, T.R.5    Caron, M.G.6
  • 94
    • 19344363080 scopus 로고    scopus 로고
    • The apical determinants aPKC and dPatj regulate frizzled-dependent planar cell polarity in the Drosophila eye
    • DOI 10.1016/j.cell.2005.03.014, PII S0092867405002862
    • A. Djiane, S. Yogev, and M. Mlodzik The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye Cell 121 2005 621 631 (Pubitemid 40720014)
    • (2005) Cell , vol.121 , Issue.4 , pp. 621-631
    • Djiane, A.1    Yogev, S.2    Mlodzik, M.3
  • 95
    • 34548439826 scopus 로고    scopus 로고
    • How do Receptors Activate G Proteins?
    • DOI 10.1016/S0065-3233(07)74002-0, PII S0065323307740020, Mechanisms and Pathways of Heterotrimeric G Protein Signaling
    • W.M. Oldham, and H.E. Hamm How do receptors activate G proteins? Adv Protein Chem 74 2007 67 93 (Pubitemid 47369747)
    • (2007) Advances in Protein Chemistry , vol.74 , pp. 67-93
    • Oldham, W.M.1    Hamm, H.E.2
  • 96
    • 0038540318 scopus 로고    scopus 로고
    • Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors
    • DOI 10.1016/S0163-7258(03)00051-2
    • E. Hermans Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors Pharmacol Ther 99 2003 25 44 (Pubitemid 36694748)
    • (2003) Pharmacology and Therapeutics , vol.99 , Issue.1 , pp. 25-44
    • Hermans, E.1
  • 97
    • 0035101820 scopus 로고    scopus 로고
    • Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
    • S.S. Ferguson Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling Pharmacol Rev 53 2001 1 24 (Pubitemid 32173106)
    • (2001) Pharmacological Reviews , vol.53 , Issue.1 , pp. 1-24
    • Ferguson, S.S.G.1
  • 98
    • 33846637432 scopus 로고    scopus 로고
    • Kinetic diversity in G-protein-coupled receptor signalling
    • DOI 10.1042/BJ20060517
    • V.L. Katanaev, and M. Chornomorets Kinetic diversity in G-protein-coupled receptor signalling Biochem J 401 2007 485 495 (Pubitemid 46170323)
    • (2007) Biochemical Journal , vol.401 , Issue.2 , pp. 485-495
    • Katanaev, V.L.1    Chornomorets, M.2
  • 99
    • 0032402450 scopus 로고    scopus 로고
    • Molecular basis of receptor/G-protein-coupling selectivity
    • DOI 10.1016/S0163-7258(98)00030-8, PII S0163725898000308
    • J. Wess Molecular basis of receptor/G-protein-coupling selectivity Pharmacol Ther 80 1998 231 264 (Pubitemid 28537822)
    • (1998) Pharmacology and Therapeutics , vol.80 , Issue.3 , pp. 231-264
    • Wess, J.1
  • 100
    • 0035224578 scopus 로고    scopus 로고
    • Prediction of the coupling specificity of G protein coupled receptors to their G proteins
    • S. Moller, J. Vilo, and M.D. Croning Prediction of the coupling specificity of G protein coupled receptors to their G proteins Bioinformatics 17 Suppl. 1 2001 S174 S181
    • (2001) Bioinformatics , vol.17 , Issue.SUPPL. 1
    • Moller, S.1    Vilo, J.2    Croning, M.D.3
  • 101
    • 27944445874 scopus 로고    scopus 로고
    • Prediction of the coupling specificity of GPCRs to four families of G-proteins using hidden Markov models and artificial neural networks
    • DOI 10.1093/bioinformatics/bti679
    • N.G. Sgourakis, P.G. Bagos, and S.J. Hamodrakas Prediction of the coupling specificity of GPCRs to four families of G-proteins using hidden Markov models and artificial neural networks Bioinformatics 21 2005 4101 4106 (Pubitemid 41672099)
    • (2005) Bioinformatics , vol.21 , Issue.22 , pp. 4101-4106
    • Sgourakis, N.G.1    Bagos, P.G.2    Hamodrakas, S.J.3
  • 102
    • 33748254329 scopus 로고    scopus 로고
    • Predicting G-protein coupled receptors-G-protein coupling specificity based on autocross-covariance transform
    • DOI 10.1002/prot.21097
    • Y. Guo, M. Li, M. Lu, Z. Wen, and Z. Huang Predicting G-protein coupled receptors-G-protein coupling specificity based on autocross-covariance transform Proteins 65 2006 55 60 (Pubitemid 44320616)
    • (2006) Proteins: Structure, Function and Genetics , vol.65 , Issue.1 , pp. 55-60
    • Guo, Y.1    Li, M.2    Lu, M.3    Wen, Z.4    Huang, Z.5
  • 103
    • 0033585001 scopus 로고    scopus 로고
    • o function
    • T. Liu, X. Liu, H. Wang, R.T. Moon, and C.C. Malbon Activation of rat frizzled-1 promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via pathways that require Galpha(q) and Galpha(o) function J Biol Chem 274 1999 33539 33544 (Pubitemid 129511663)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.47 , pp. 33539-33544
    • Liu, T.1    Liu, X.2    Wang, H.-Y.3    Moon, R.T.4    Malbon, C.C.5
  • 104
    • 2242453282 scopus 로고    scopus 로고
    • Signaling of rat frizzled-2 through phosphodiesterase and cyclic GMP
    • DOI 10.1126/science.1073776
    • A. Ahumada, D.C. Slusarski, X. Liu, R.T. Moon, C.C. Malbon, and H.Y. Wang Signaling of rat Frizzled-2 through phosphodiesterase and cyclic GMP Science 298 2002 2006 2010 (Pubitemid 35425259)
    • (2002) Science , vol.298 , Issue.5600 , pp. 2006-2010
    • Ahumada, A.1    Slusarski, D.C.2    Liu, X.3    Moon, R.T.4    Malbon, C.C.5    Wang, H.-Y.6
  • 105
    • 0021748090 scopus 로고
    • Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain
    • P.C. Sternweis, and J.D. Robishaw Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain J Biol Chem 259 1984 13806 13813 (Pubitemid 15224957)
    • (1984) Journal of Biological Chemistry , vol.259 , Issue.22 , pp. 13806-13813
    • Sternweis, P.C.1    Robishaw, J.D.2
  • 108
    • 42549090080 scopus 로고    scopus 로고
    • i/o signaling pathways
    • DOI 10.2741/3022
    • K.D. Bromberg, R. Iyengar, and J.C. He Regulation of neurite outgrowth by G(i/o) signaling pathways Front Biosci 13 2008 4544 4557 (Pubitemid 351589181)
    • (2008) Frontiers in Bioscience , vol.13 , Issue.12 , pp. 4544-4557
    • Bromberg, K.D.1    Iyengar, R.2    He, J.C.3
  • 110
    • 0033620488 scopus 로고    scopus 로고
    • The heterotrimeric protein G(o) is required for the formation of heart epithelium in Drosophila
    • DOI 10.1083/jcb.145.5.1063
    • F. Fremion, M. Astier, S. Zaffran, A. Guillen, V. Homburger, and M. Semeriva The heterotrimeric protein Go is required for the formation of heart epithelium in Drosophila J Cell Biol 145 1999 1063 1076 (Pubitemid 29270063)
    • (1999) Journal of Cell Biology , vol.145 , Issue.5 , pp. 1063-1076
    • Fremion, F.1    Astier, M.2    Zaffran, S.3    Guillen, A.4    Homburger, V.5    Semeriva, M.6
  • 112
    • 25444482429 scopus 로고    scopus 로고
    • Mammalian G proteins and their cell type specific functions
    • DOI 10.1152/physrev.00003.2005
    • N. Wettschureck, and S. Offermanns Mammalian G proteins and their cell type specific functions Physiol Rev 85 2005 1159 1204 (Pubitemid 41362268)
    • (2005) Physiological Reviews , vol.85 , Issue.4 , pp. 1159-1204
    • Wettschureck, N.1    Offermanns, S.2
  • 113
    • 79953647554 scopus 로고    scopus 로고
    • Heterotrimeric G protein signaling in cancer cells with regard to metastasis formation
    • F. Entschladen, K.S. Zanker, and D.G. Powe Heterotrimeric G protein signaling in cancer cells with regard to metastasis formation Cell Cycle 10 2011 1086 1091
    • (2011) Cell Cycle , vol.10 , pp. 1086-1091
    • Entschladen, F.1    Zanker, K.S.2    Powe, D.G.3
  • 114
    • 0026613085 scopus 로고
    • The Q205LGo-alpha subunit expressed in NIH-3T3 cells induces transformation
    • S.D. Kroll, J. Chen, M. De Vivo, D.J. Carty, A. Buku, and R.T. Premont The Q205LGo-alpha subunit expressed in NIH-3T3 cells induces transformation J Biol Chem 267 1992 23183 23188
    • (1992) J Biol Chem , vol.267 , pp. 23183-23188
    • Kroll, S.D.1    Chen, J.2    De Vivo, M.3    Carty, D.J.4    Buku, A.5    Premont, R.T.6
  • 115
    • 0034614695 scopus 로고    scopus 로고
    • Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Gα(o) protein
    • DOI 10.1126/science.287.5450.142
    • P.T. Ram, C.M. Horvath, and R. Iyengar Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein Science 287 2000 142 144 (Pubitemid 30033239)
    • (2000) Science , vol.287 , Issue.5450 , pp. 142-144
    • Ram, P.T.1    Horvath, C.M.2    Iyengar, R.3
  • 116
  • 117
    • 77955660663 scopus 로고    scopus 로고
    • Diverse somatic mutation patterns and pathway alterations in human cancers
    • Z. Kan, B.S. Jaiswal, J. Stinson, V. Janakiraman, D. Bhatt, and H.M. Stern Diverse somatic mutation patterns and pathway alterations in human cancers Nature 466 2010 869 873
    • (2010) Nature , vol.466 , pp. 869-873
    • Kan, Z.1    Jaiswal, B.S.2    Stinson, J.3    Janakiraman, V.4    Bhatt, D.5    Stern, H.M.6
  • 119
    • 60149091355 scopus 로고    scopus 로고
    • Molecular mechanisms of go signaling
    • M. Jiang, and N.S. Bajpayee Molecular mechanisms of go signaling Neurosignals 17 2009 23 41
    • (2009) Neurosignals , vol.17 , pp. 23-41
    • Jiang, M.1    Bajpayee, N.S.2
  • 120
    • 0033618396 scopus 로고    scopus 로고
    • Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein
    • J.D. Jordan, K.D. Carey, P.J. Stork, and R. Iyengar Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein J Biol Chem 274 1999 21507 21510
    • (1999) J Biol Chem , vol.274 , pp. 21507-21510
    • Jordan, J.D.1    Carey, K.D.2    Stork, P.J.3    Iyengar, R.4
  • 121
    • 70349318469 scopus 로고    scopus 로고
    • Drosophila GoLoco-protein pins is a target of Galpha(o)-mediated G protein-coupled receptor signaling
    • D. Kopein, and V.L. Katanaev Drosophila GoLoco-protein pins is a target of Galpha(o)-mediated G protein-coupled receptor signaling Mol Biol Cell 20 2009 3865 3877
    • (2009) Mol Biol Cell , vol.20 , pp. 3865-3877
    • Kopein, D.1    Katanaev, V.L.2
  • 123
  • 124
    • 0034611690 scopus 로고    scopus 로고
    • A protein complex containing inscuteable and the Gα-binding protein pins orients asymmetric cell divisions in Drosophila
    • DOI 10.1016/S0960-9822(00)00401-2
    • M. Schaefer, A. Shevchenko, A. Shevchenko, and J.A. Knoblich A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila Curr Biol 10 2000 353 362 (Pubitemid 30213381)
    • (2000) Current Biology , vol.10 , Issue.7 , pp. 353-362
    • Schaefer, M.1    Shevchenko, A.2    Shevchenko, A.3    Knoblich, J.A.4
  • 125
    • 0034745355 scopus 로고    scopus 로고
    • Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorhabditis elegans embryos
    • DOI 10.1038/35060092
    • M. Gotta, and J. Ahringer Distinct roles for Galpha and Gbetagamma in regulating spindle position and orientation in Caenorhabditis elegans embryos Nat Cell Biol 3 2001 297 300 (Pubitemid 32201325)
    • (2001) Nature Cell Biology , vol.3 , Issue.3 , pp. 297-300
    • Gotta, M.1    Ahringer, J.2
  • 126
    • 0038046388 scopus 로고    scopus 로고
    • Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos
    • DOI 10.1126/science.1084146
    • K. Colombo, S.W. Grill, R.J. Kimple, F.S. Willard, D.P. Siderovski, and P. Gonczy Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos Science 300 2003 1957 1961 (Pubitemid 36734605)
    • (2003) Science , vol.300 , Issue.5627 , pp. 1957-1961
    • Colombo, K.1    Grill, S.W.2    Kimple, R.J.3    Willard, F.S.4    Siderovski, D.P.5    Gonczy, P.6
  • 127
    • 0036733358 scopus 로고    scopus 로고
    • Cellular regulation of RGS proteins: Modulators and integrators of G protein signaling
    • S. Hollinger, and J.R. Hepler Cellular regulation of RGS proteins: modulators and integrators of G protein signaling Pharmacol Rev 54 2002 527 559
    • (2002) Pharmacol Rev , vol.54 , pp. 527-559
    • Hollinger, S.1    Hepler, J.R.2
  • 128
    • 0034663469 scopus 로고    scopus 로고
    • RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao
    • S. Traver, C. Bidot, N. Spassky, T. Baltauss, M.F. De Tand, and J.L. Thomas RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao Biochem J 350 Pt 1 2000 19 29
    • (2000) Biochem J , vol.350 , Issue.PART 1 , pp. 19-29
    • Traver, S.1    Bidot, C.2    Spassky, N.3    Baltauss, T.4    De Tand, M.F.5    Thomas, J.L.6
  • 129
    • 55349112214 scopus 로고    scopus 로고
    • Heterotrimeric G proteins regulate a noncanonical function of septate junction proteins to maintain cardiac integrity in Drosophila
    • P. Yi, A.N. Johnson, Z. Han, J. Wu, and E.N. Olson Heterotrimeric G proteins regulate a noncanonical function of septate junction proteins to maintain cardiac integrity in Drosophila Dev Cell 15 2008 704 713
    • (2008) Dev Cell , vol.15 , pp. 704-713
    • Yi, P.1    Johnson, A.N.2    Han, Z.3    Wu, J.4    Olson, E.N.5
  • 131
    • 0027447656 scopus 로고
    • Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)
    • DOI 10.1038/362075a0
    • I. Nishimoto, T. Okamoto, Y. Matsuura, S. Takahashi, Y. Murayama, and E. Ogata Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o) Nature 362 1993 75 79 (Pubitemid 23087295)
    • (1993) Nature , vol.362 , Issue.6415 , pp. 75-79
    • Nishimoto, I.1    Okamoto, T.2    Matsuura, Y.3    Takahashi, S.4    Okamoto, T.5    Murayama, Y.6    Ogata, E.7
  • 132
    • 0038234801 scopus 로고    scopus 로고
    • G-proteins as transducers in transmembrane signalling
    • DOI 10.1016/S0079-6107(03)00052-X
    • S. Offermanns G-proteins as transducers in transmembrane signalling Prog Biophys Mol Biol 83 2003 101 130 (Pubitemid 36832209)
    • (2003) Progress in Biophysics and Molecular Biology , vol.83 , Issue.2 , pp. 101-130
    • Offermanns, S.1
  • 133
    • 77956626816 scopus 로고    scopus 로고
    • Competing activities of heterotrimeric G proteins in Drosophila wing maturation
    • N. Katanayeva, D. Kopein, R. Portmann, D. Hess, and V.L. Katanaev Competing activities of heterotrimeric G proteins in Drosophila wing maturation PLoS ONE 5 2010 e12331
    • (2010) PLoS ONE , vol.5 , pp. 12331
    • Katanayeva, N.1    Kopein, D.2    Portmann, R.3    Hess, D.4    Katanaev, V.L.5
  • 134
    • 69249137477 scopus 로고    scopus 로고
    • Endocytosis and signalling: Intertwining molecular networks
    • A. Sorkin, and M. von Zastrow Endocytosis and signalling: intertwining molecular networks Nat Rev Mol Cell Biol 10 2009 609 622
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 609-622
    • Sorkin, A.1    Von Zastrow, M.2
  • 135
    • 33645732587 scopus 로고    scopus 로고
    • Internalization is required for proper Wingless signaling in Drosophila melanogaster
    • E.S. Seto, and H.J. Bellen Internalization is required for proper Wingless signaling in Drosophila melanogaster J Cell Biol 173 2006 95 106
    • (2006) J Cell Biol , vol.173 , pp. 95-106
    • Seto, E.S.1    Bellen, H.J.2
  • 136
    • 33746960721 scopus 로고    scopus 로고
    • A critical role for endocytosis in Wnt signaling
    • J.T. Blitzer, and R. Nusse A critical role for endocytosis in Wnt signaling BMC Cell Biol 7 2006 28
    • (2006) BMC Cell Biol , vol.7 , pp. 28
    • Blitzer, J.T.1    Nusse, R.2
  • 138
    • 37249092938 scopus 로고    scopus 로고
    • Endocytosis: A positive or a negative influence on wnt signalling?
    • DOI 10.1111/j.1600-0854.2007.00662.x
    • M. Gagliardi, E. Piddini, and J.P. Vincent Endocytosis: a positive or a negative influence on Wnt signalling? Traffic 9 2008 1 9 (Pubitemid 350263458)
    • (2008) Traffic , vol.9 , Issue.1 , pp. 1-9
    • Gagliardi, M.1    Piddini, E.2    Vincent, J.-P.3
  • 139
    • 61449249121 scopus 로고    scopus 로고
    • Selective activation mechanisms of Wnt signaling pathways
    • A. Kikuchi, H. Yamamoto, and A. Sato Selective activation mechanisms of Wnt signaling pathways Trends Cell Biol 19 2009 119 129
    • (2009) Trends Cell Biol , vol.19 , pp. 119-129
    • Kikuchi, A.1    Yamamoto, H.2    Sato, A.3
  • 140
    • 33845875500 scopus 로고    scopus 로고
    • Association of Dishevelled with the Clathrin AP-2 Adaptor Is Required for Frizzled Endocytosis and Planar Cell Polarity Signaling
    • DOI 10.1016/j.devcel.2006.10.015, PII S1534580706004679
    • A. Yu, J.F. Rual, K. Tamai, Y. Harada, M. Vidal, and X. He Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling Dev Cell 12 2007 129 141 (Pubitemid 46019421)
    • (2007) Developmental Cell , vol.12 , Issue.1 , pp. 129-141
    • Yu, A.1    Rual, J.-F.2    Tamai, K.3    Harada, Y.4    Vidal, M.5    He, X.6    Kirchhausen, T.7
  • 141
    • 33746482870 scopus 로고    scopus 로고
    • Caveolin Is Necessary for Wnt-3a-Dependent Internalization of LRP6 and Accumulation of β-Catenin
    • DOI 10.1016/j.devcel.2006.07.003, PII S1534580706003042
    • H. Yamamoto, H. Komekado, and A. Kikuchi Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin Dev Cell 11 2006 213 223 (Pubitemid 44138502)
    • (2006) Developmental Cell , vol.11 , Issue.2 , pp. 213-223
    • Yamamoto, H.1    Komekado, H.2    Kikuchi, A.3
  • 144
    • 78651295086 scopus 로고    scopus 로고
    • Rab GTPases bind at a common site within the angiotensin II type i receptor carboxyl-terminal tail: Evidence that Rab4 regulates receptor phosphorylation, desensitization, and resensitization
    • J.L. Esseltine, L.B. Dale, and S.S. Ferguson Rab GTPases bind at a common site within the angiotensin II type I receptor carboxyl-terminal tail: evidence that Rab4 regulates receptor phosphorylation, desensitization, and resensitization Mol Pharmacol 79 2011 175 184
    • (2011) Mol Pharmacol , vol.79 , pp. 175-184
    • Esseltine, J.L.1    Dale, L.B.2    Ferguson, S.S.3
  • 145
    • 27744469168 scopus 로고    scopus 로고
    • The intracellular trafficking of the G protein-coupled receptor TPβ depends on a direct interaction with Rab11
    • DOI 10.1074/jbc.M503438200
    • E. Hamelin, C. Theriault, G. Laroche, and J.L. Parent The intracellular trafficking of the G protein-coupled receptor TPbeta depends on a direct interaction with Rab11 J Biol Chem 280 2005 36195 36205 (Pubitemid 41633892)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.43 , pp. 36195-36205
    • Hamelin, E.1    Theriault, C.2    Laroche, G.3    Parent, J.-L.4
  • 146
    • 59849102081 scopus 로고    scopus 로고
    • Rab11 regulates the recycling of the beta2-adrenergic receptor through a direct interaction
    • A. Parent, E. Hamelin, P. Germain, and J.L. Parent Rab11 regulates the recycling of the beta2-adrenergic receptor through a direct interaction Biochem J 418 2009 163 172
    • (2009) Biochem J , vol.418 , pp. 163-172
    • Parent, A.1    Hamelin, E.2    Germain, P.3    Parent, J.L.4
  • 147
    • 3142585284 scopus 로고    scopus 로고
    • Controlling the location and activation of Rab GTPases
    • DOI 10.1016/j.ceb.2004.06.014, PII S0955067404000833
    • M.C. Seabra, and C. Wasmeier Controlling the location and activation of Rab GTPases Curr Opin Cell Biol 16 2004 451 457 (Pubitemid 38903152)
    • (2004) Current Opinion in Cell Biology , vol.16 , Issue.4 , pp. 451-457
    • Seabra, M.C.1    Wasmeier, C.2
  • 148
    • 0034625641 scopus 로고    scopus 로고
    • Signaling specificity by frizzled receptors in Drosophila
    • DOI 10.1126/science.288.5472.1825
    • M. Boutros, J. Mihaly, T. Bouwmeester, and M. Mlodzik Signaling specificity by Frizzled receptors in Drosophila Science 288 2000 1825 1828 (Pubitemid 30399020)
    • (2000) Science , vol.288 , Issue.5472 , pp. 1825-1828
    • Boutros, M.1    Mihaly, J.2    Bouwmeester, T.3    Mlodzik, M.4
  • 149
    • 0035210992 scopus 로고    scopus 로고
    • Transducing properties of Drosophila Frizzled proteins
    • W.R. Strapps, and A. Tomlinson Transducing properties of Drosophila Frizzled proteins Development 128 2001 4829 4835 (Pubitemid 33138592)
    • (2001) Development , vol.128 , Issue.23 , pp. 4829-4835
    • Strapps, W.R.1    Tomlinson, A.2
  • 150
    • 0033398530 scopus 로고    scopus 로고
    • Wingless transduction by the Frizzled and Frizzled2 proteins of Drosophila
    • C.M. Chen, and G. Struhl Wingless transduction by the Frizzled and Frizzled2 proteins of Drosophila Development 126 1999 5441 5452 (Pubitemid 30015936)
    • (1999) Development , vol.126 , Issue.23 , pp. 5441-5452
    • Chen, C.-M.1    Struhl, G.2
  • 151
    • 0032588683 scopus 로고    scopus 로고
    • Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development
    • P. Bhanot, M. Fish, J.A. Jemison, R. Nusse, J. Nathans, and K.M. Cadigan Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development Development 1999
    • (1999) Development
    • Bhanot, P.1    Fish, M.2    Jemison, J.A.3    Nusse, R.4    Nathans, J.5    Cadigan, K.M.6
  • 152
    • 0032577556 scopus 로고    scopus 로고
    • Wingless repression of Drosophila frizzled 2 expression SHAPES THE wingless morphogen gradient in the wing
    • DOI 10.1016/S0092-8674(00)81438-5
    • K.M. Cadigan, M.P. Fish, E.J. Rulifson, and R. Nusse Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing Cell 93 1998 767 777 (Pubitemid 28257583)
    • (1998) Cell , vol.93 , Issue.5 , pp. 767-777
    • Cadigan, K.M.1    Fish, M.P.2    Rulifson, E.J.3    Nusse, R.4
  • 153
    • 0028345607 scopus 로고
    • The wingless signalling pathway and the patterning of the wing margin in Drosophila
    • J.P. Couso, S.A. Bishop, and A. Martinez Arias The wingless signalling pathway and the patterning of the wing margin in Drosophila Development 120 1994 621 636 (Pubitemid 24071204)
    • (1994) Development , vol.120 , Issue.3 , pp. 621-636
    • Couso, J.P.1    Bishop, S.A.2    Martinez Arias, A.3
  • 154
    • 1842507650 scopus 로고    scopus 로고
    • Axin: A master scaffold for multiple signaling pathways
    • DOI 10.1159/000076563
    • W. Luo, and S.C. Lin Axin: a master scaffold for multiple signaling pathways Neurosignals 13 2004 99 113 (Pubitemid 38456651)
    • (2004) NeuroSignals , vol.13 , Issue.3 , pp. 99-113
    • Luo, W.1    Lin, S.-C.2
  • 155
  • 157
    • 28644444440 scopus 로고    scopus 로고
    • Casein kinase 1γ couples Wnt receptor activation to cytoplasmic signal transduction
    • DOI 10.1038/nature04170
    • G. Davidson, W. Wu, J. Shen, J. Bilic, U. Fenger, and P. Stannek Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction Nature 438 2005 867 872 (Pubitemid 41753070)
    • (2005) Nature , vol.438 , Issue.7069 , pp. 867-872
    • Davidson, G.1    Wu, W.2    Shen, J.3    Bilic, J.4    Fenger, U.5    Stannek, P.6    Glinka, A.7    Niehrs, C.8
  • 158
    • 28644439005 scopus 로고    scopus 로고
    • A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
    • DOI 10.1038/nature04185
    • X. Zeng, K. Tamai, B. Doble, S. Li, H. Huang, and R. Habas A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation Nature 438 2005 873 877 (Pubitemid 41753071)
    • (2005) Nature , vol.438 , Issue.7069 , pp. 873-877
    • Zeng, X.1    Tamai, K.2    Doble, B.3    Li, S.4    Huang, H.5    Habas, R.6    Okamura, H.7    Woodgett, J.8    He, X.9
  • 159
    • 33645714061 scopus 로고    scopus 로고
    • The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation
    • S. Angers, C.J. Thorpe, T.L. Biechele, S.J. Goldenberg, N. Zheng, and M.J. MacCoss The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation Nat Cell Biol 8 2006 348 357
    • (2006) Nat Cell Biol , vol.8 , pp. 348-357
    • Angers, S.1    Thorpe, C.J.2    Biechele, T.L.3    Goldenberg, S.J.4    Zheng, N.5    MacCoss, M.J.6
  • 160
    • 70350712270 scopus 로고    scopus 로고
    • Negative feedback regulation of Wnt signaling by Gbetagamma-mediated reduction of Dishevelled
    • H. Jung, H.J. Kim, S.K. Lee, R. Kim, W. Kopachik, and J.K. Han Negative feedback regulation of Wnt signaling by Gbetagamma-mediated reduction of Dishevelled Exp Mol Med 41 2009 695 706
    • (2009) Exp Mol Med , vol.41 , pp. 695-706
    • Jung, H.1    Kim, H.J.2    Lee, S.K.3    Kim, R.4    Kopachik, W.5    Han, J.K.6
  • 161
    • 33846235822 scopus 로고    scopus 로고
    • Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate β-catenin
    • DOI 10.1016/j.cellsig.2006.08.011, PII S0898656806002051
    • V. Bryja, G. Schulte, and E. Arenas Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin Cell Signal 19 2007 610 616 (Pubitemid 46107812)
    • (2007) Cellular Signalling , vol.19 , Issue.3 , pp. 610-616
    • Bryja, V.1    Schulte, G.2    Arenas, E.3
  • 162
    • 28544444039 scopus 로고    scopus 로고
    • s-axin-β-catenin signaling axis
    • DOI 10.1126/science.1116221
    • M.D. Castellone, H. Teramoto, B.O. Williams, K.M. Druey, and J.S. Gutkind Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis Science 310 2005 1504 1510 (Pubitemid 41746348)
    • (2005) Science , vol.310 , Issue.5753 , pp. 1504-1510
    • Castellone, M.D.1    Teramoto, H.2    Williams, B.O.3    Druey, K.M.4    Gutkind, J.S.5
  • 163
    • 33748938039 scopus 로고    scopus 로고
    • 13
    • DOI 10.1124/mol.106.023705
    • L.N. Stemmle, T.A. Fields, and P.J. Casey The regulator of G protein signaling domain of axin selectively interacts with Galpha12 but not Galpha13 Mol Pharmacol 70 2006 1461 1468 (Pubitemid 44435999)
    • (2006) Molecular Pharmacology , vol.70 , Issue.4 , pp. 1461-1468
    • Stemmle, L.N.1    Fields, T.A.2    Casey, P.J.3
  • 164
    • 33748567853 scopus 로고    scopus 로고
    • PDZ-domain arrays for identifying components of GPCR signaling complexes
    • DOI 10.1016/j.tips.2006.08.003, PII S0165614706001830
    • P. Day, and B. Kobilka PDZ-domain arrays for identifying components of GPCR signaling complexes Trends Pharmacol Sci 27 2006 509 511 (Pubitemid 44374757)
    • (2006) Trends in Pharmacological Sciences , vol.27 , Issue.10 , pp. 509-511
    • Day, P.1    Kobilka, B.2
  • 165
    • 29244462476 scopus 로고    scopus 로고
    • The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles
    • DOI 10.1242/jcs.02646
    • T. Schwarz-Romond, C. Merrifield, B.J. Nichols, and M. Bienz The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles J Cell Sci 118 2005 5269 5277 (Pubitemid 41819589)
    • (2005) Journal of Cell Science , vol.118 , Issue.22 , pp. 5269-5277
    • Schwarz-Romond, T.1    Merrifield, C.2    Nichols, B.J.3    Bienz, M.4
  • 166
    • 34250827150 scopus 로고    scopus 로고
    • Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
    • DOI 10.1126/science.1137065
    • J. Bilic, Y.L. Huang, G. Davidson, T. Zimmermann, C.M. Cruciat, and M. Bienz Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation Science 316 2007 1619 1622 (Pubitemid 46982035)
    • (2007) Science , vol.316 , Issue.5831 , pp. 1619-1622
    • Bilic, J.1    Huang, Y.-L.2    Davidson, G.3    Zimmermann, T.4    Cruciat, C.-M.5    Bienz, M.6    Niehrs, C.7
  • 168
    • 78149344606 scopus 로고    scopus 로고
    • Wnt-dependent assembly of supermolecular Dishevelled-3-based complexes
    • N. Yokoyama, U. Golebiewska, H.Y. Wang, and C.C. Malbon Wnt-dependent assembly of supermolecular Dishevelled-3-based complexes J Cell Sci 123 2010 3693 3702
    • (2010) J Cell Sci , vol.123 , pp. 3693-3702
    • Yokoyama, N.1    Golebiewska, U.2    Wang, H.Y.3    Malbon, C.C.4
  • 169
    • 36148944785 scopus 로고    scopus 로고
    • When a G protein-coupled receptor does not couple to a G protein
    • DOI 10.1039/b706343a
    • Y. Sun, D. McGarrigle, and X.Y. Huang When a G protein-coupled receptor does not couple to a G protein Mol Biosyst 3 2007 849 854 (Pubitemid 350115412)
    • (2007) Molecular BioSystems , vol.3 , Issue.12 , pp. 849-854
    • Sun, Y.1    McGarrigle, D.2    Huang, X.-Y.3
  • 170
    • 78651373139 scopus 로고    scopus 로고
    • New avenues to target Wnt/beta-catenin signaling
    • F. Verkaar, and G.J. Zaman New avenues to target Wnt/beta-catenin signaling Drug Discov Today 16 2011 35 41
    • (2011) Drug Discov Today , vol.16 , pp. 35-41
    • Verkaar, F.1    Zaman, G.J.2


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