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Volumn 13, Issue 3, 2004, Pages 99-113

Axin: A master scaffold for multiple signaling pathways

Author keywords

Axin, biological function; Axin, identification; Axin JNK signaling pathway; Wnt pathway

Indexed keywords

AXIN; BETA CATENIN; CASEIN KINASE; PHOSPHOPROTEIN PHOSPHATASE 2A; STRESS ACTIVATED PROTEIN KINASE; WNT PROTEIN;

EID: 1842507650     PISSN: 1424862X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000076563     Document Type: Review
Times cited : (136)

References (133)
  • 1
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • Wodarz A, Nusse R: Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol 1998;14:59-88.
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 2
    • 0036794477 scopus 로고    scopus 로고
    • Increasingly complex: New players enter the Wnt signaling network
    • Pandur P, Maurus D, Kuhl M: Increasingly complex: New players enter the Wnt signaling network. Bioessays 2002;24:881-884.
    • (2002) Bioessays , vol.24 , pp. 881-884
    • Pandur, P.1    Maurus, D.2    Kuhl, M.3
  • 4
    • 0034727099 scopus 로고    scopus 로고
    • arrow encodes an LDL-receptor-related protein essential for Wingless signaling
    • Wehrli M, Dougan ST, Caldwell K, O'Keefe L, Schwartz S, Vaizel D: arrow encodes an LDL-receptor-related protein essential for Wingless signaling. Nature 2000;407:527-530.
    • (2000) Nature , vol.407 , pp. 527-530
    • Wehrli, M.1    Dougan, S.T.2    Caldwell, K.3    O'Keefe, L.4    Schwartz, S.5    Vaizel, D.6
  • 5
    • 0037343952 scopus 로고    scopus 로고
    • Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/GSK-3β activity
    • Tolwinski NS, Wehrli M, Rives A, Erdeniz N, DiNardo S, Wieschaus E: Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/GSK-3β activity. Dev Cell 2003;4:407-418.
    • (2003) Dev Cell , vol.4 , pp. 407-418
    • Tolwinski, N.S.1    Wehrli, M.2    Rives, A.3    Erdeniz, N.4    DiNardo, S.5    Wieschaus, E.6
  • 6
    • 0033011602 scopus 로고    scopus 로고
    • DIX domains of Dvl and Axin are necessary for protein interactions and their ability to regulate β-catenin stability
    • Kishida S, Yamamoto H, Hino S, Ikeda M, Kishida M, Kikuchi A: DIX domains of Dvl and Axin are necessary for protein interactions and their ability to regulate β-catenin stability. Mol Cell Biol 1999;19:4414-4422.
    • (1999) Mol Cell Biol , vol.19 , pp. 4414-4422
    • Kishida, S.1    Yamamoto, H.2    Hino, S.3    Ikeda, M.4    Kishida, M.5    Kikuchi, A.6
  • 8
    • 0032079884 scopus 로고    scopus 로고
    • Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin
    • Kishida S, Yamamoto H, Ikeda S, Kishida M, Sakamoto I, Koyama S, Kikuchi A: Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin. J Biol Chem 1998;273:10823-10826.
    • (1998) J Biol Chem , vol.273 , pp. 10823-10826
    • Kishida, S.1    Yamamoto, H.2    Ikeda, S.3    Kishida, M.4    Sakamoto, I.5    Koyama, S.6    Kikuchi, A.7
  • 9
    • 0032492954 scopus 로고    scopus 로고
    • Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK-3β
    • Hart MJ, de los Santos R, Albert IN, Rubinfeld B, Polakis P: Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK-3β. Curr Biol 1998;8:573-581.
    • (1998) Curr Biol , vol.8 , pp. 573-581
    • Hart, M.J.1    De Los Santos, R.2    Albert, I.N.3    Rubinfeld, B.4    Polakis, P.5
  • 10
    • 0031813650 scopus 로고    scopus 로고
    • Axin, an inhibitor of the Wnt signaling pathway, interacts with β-catenin, GSK-3β and APC and reduces the β-catenin level
    • Nakamura T, Hamada F, Ishidate T, Anai K, Kawahara K, Toyoshima K, Akiyama T: Axin, an inhibitor of the Wnt signaling pathway, interacts with β-catenin, GSK-3β and APC and reduces the β-catenin level. Genes Cells 1998;3:395-403.
    • (1998) Genes Cells , vol.3 , pp. 395-403
    • Nakamura, T.1    Hamada, F.2    Ishidate, T.3    Anai, K.4    Kawahara, K.5    Toyoshima, K.6    Akiyama, T.7
  • 11
    • 0035914460 scopus 로고    scopus 로고
    • Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase Iε
    • Rubinfeld B, Tice DA, Polakis P: Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase Iε. J Biol Chem 2001;276:39037-39045.
    • (2001) J Biol Chem , vol.276 , pp. 39037-39045
    • Rubinfeld, B.1    Tice, D.A.2    Polakis, P.3
  • 12
    • 0033524929 scopus 로고    scopus 로고
    • Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain
    • Hsu W, Zeng L, Costantini F: Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain. J Biol Chem 1999;274:3439-3445.
    • (1999) J Biol Chem , vol.274 , pp. 3439-3445
    • Hsu, W.1    Zeng, L.2    Costantini, F.3
  • 13
    • 0037102507 scopus 로고    scopus 로고
    • The ankyrin repeat protein diversin recruits casein kinase Iε to the β-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling
    • Schwarz-Romond T, Asbrand C, Bakkers J, Kuhl M, Schaeffer HJ, Huelsken J, Behrens J, Hammerschmidt M, Birchmeier W: The ankyrin repeat protein diversin recruits casein kinase Iε to the β-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev 2002;16:2073-2084.
    • (2002) Genes Dev , vol.16 , pp. 2073-2084
    • Schwarz-Romond, T.1    Asbrand, C.2    Bakkers, J.3    Kuhl, M.4    Schaeffer, H.J.5    Huelsken, J.6    Behrens, J.7    Hammerschmidt, M.8    Birchmeier, W.9
  • 14
    • 0037425625 scopus 로고    scopus 로고
    • Ccd1, a novel protein with a DIX domain, is a positive regulator in the Wnt signaling during zebrafish neural patterning
    • Shiomi K, Uchida H, Keino-Masu K, Masu M: Ccd1, a novel protein with a DIX domain, is a positive regulator in the Wnt signaling during zebrafish neural patterning. Curr Biol 2003;13:73-77.
    • (2003) Curr Biol , vol.13 , pp. 73-77
    • Shiomi, K.1    Uchida, H.2    Keino-Masu, K.3    Masu, M.4
  • 16
    • 0037513408 scopus 로고    scopus 로고
    • A role of Dishevelled in relocating axin to the plasma membrane during wingless signaling
    • Cliffe A, Hamada F, Bienz M: A role of Dishevelled in relocating axin to the plasma membrane during wingless signaling. Curr Biol 2003;13:960-966.
    • (2003) Curr Biol , vol.13 , pp. 960-966
    • Cliffe, A.1    Hamada, F.2    Bienz, M.3
  • 17
    • 0033574527 scopus 로고    scopus 로고
    • Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3β regulates its stability
    • Yamamoto H, Kishida S, Kishida M, Ikeda S, Takada S, Kikuchi A: Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3β regulates its stability. J Biol Chem 1999;274:10681-10684.
    • (1999) J Biol Chem , vol.274 , pp. 10681-10684
    • Yamamoto, H.1    Kishida, S.2    Kishida, M.3    Ikeda, S.4    Takada, S.5    Kikuchi, A.6
  • 18
    • 0033521002 scopus 로고    scopus 로고
    • Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling
    • Zhang Y, Neo SY, Wang X, Han J, Lin SC: Axin forms a complex with MEKK1 and activates c-Jun NH(2)-terminal kinase/stress-activated protein kinase through domains distinct from Wnt signaling. J Biol Chem 1999;274:35247-35254.
    • (1999) J Biol Chem , vol.274 , pp. 35247-35254
    • Zhang, Y.1    Neo, S.Y.2    Wang, X.3    Han, J.4    Lin, S.C.5
  • 19
    • 0141621205 scopus 로고    scopus 로고
    • Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation
    • Luo W, Ng WW, Jin LH, Ye Z, Han J, Lin SC: Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation. J Biol Chem 2003;278:37451-37458.
    • (2003) J Biol Chem , vol.278 , pp. 37451-37458
    • Luo, W.1    Ng, W.W.2    Jin, L.H.3    Ye, Z.4    Han, J.5    Lin, S.C.6
  • 20
    • 0036723652 scopus 로고    scopus 로고
    • I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways
    • Kusano S, Raab-Traub N: I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways. Mol Cell Biol 2002;22:6393-6405.
    • (2002) Mol Cell Biol , vol.22 , pp. 6393-6405
    • Kusano, S.1    Raab-Traub, N.2
  • 21
    • 0036829560 scopus 로고    scopus 로고
    • Identification of DCAP, a Drosophila homolog of a glucose transport regulatory complex
    • Yamazaki H, Nusse R: Identification of DCAP, a Drosophila homolog of a glucose transport regulatory complex. Mech Dev 2002;119:115-119.
    • (2002) Mech Dev , vol.119 , pp. 115-119
    • Yamazaki, H.1    Nusse, R.2
  • 22
    • 0035855819 scopus 로고    scopus 로고
    • The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals
    • Cowan CA, Henkemeyer M: The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals. Nature 2001;413:174-179.
    • (2001) Nature , vol.413 , pp. 174-179
    • Cowan, C.A.1    Henkemeyer, M.2
  • 24
    • 0035943591 scopus 로고    scopus 로고
    • Differential molecular assemblies underlie the dual function of Axin in modulating the Wnt and JNK pathways
    • Zhang Y, Qiu WJ, Liu DX, Neo SY, He X, Lin SC: Differential molecular assemblies underlie the dual function of Axin in modulating the Wnt and JNK pathways. J Biol Chem 2001;276:32152-32159.
    • (2001) J Biol Chem , vol.276 , pp. 32152-32159
    • Zhang, Y.1    Qiu, W.J.2    Liu, D.X.3    Neo, S.Y.4    He, X.5    Lin, S.C.6
  • 25
    • 0034637591 scopus 로고    scopus 로고
    • Dimerization choices control the ability of Axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase
    • Zhang Y, Neo SY, Han J, Lin SC: Dimerization choices control the ability of Axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase. J Biol Chem 2000;275:25008-25014.
    • (2000) J Biol Chem , vol.275 , pp. 25008-25014
    • Zhang, Y.1    Neo, S.Y.2    Han, J.3    Lin, S.C.4
  • 26
    • 0037124056 scopus 로고    scopus 로고
    • Casein kinase I and casein kinase II differentially regulate Axin function in Wnt and JNK pathways
    • Zhang Y, Qiu WJ, Chan SC, Han J, He X, Lin SC: Casein kinase I and casein kinase II differentially regulate Axin function in Wnt and JNK pathways. J Biol Chem 2002;277:17706-17712.
    • (2002) J Biol Chem , vol.277 , pp. 17706-17712
    • Zhang, Y.1    Qiu, W.J.2    Chan, S.C.3    Han, J.4    He, X.5    Lin, S.C.6
  • 27
    • 0037044836 scopus 로고    scopus 로고
    • SUMO-1 modification of the C-terminal KVEKVD of Axin is required for JNK activation but has no effect on Wnt signaling
    • Rui HL, Fan E, Zhou HM, Xu Z, Zhang Y, Lin SC: SUMO-1 modification of the C-terminal KVEKVD of Axin is required for JNK activation but has no effect on Wnt signaling. J Biol Chem 2002;277:42981-42986.
    • (2002) J Biol Chem , vol.277 , pp. 42981-42986
    • Rui, H.L.1    Fan, E.2    Zhou, H.M.3    Xu, Z.4    Zhang, Y.5    Lin, S.C.6
  • 30
    • 0033623568 scopus 로고    scopus 로고
    • Unusual inheritance of the Axin Fu mutation in mice is associated with widespread rearrangements in the proximal region of chromosome 17
    • Ruvinsky A, Flood WD, Zhang T, Costantini F: Unusual inheritance of the Axin Fu mutation in mice is associated with widespread rearrangements in the proximal region of chromosome 17. Genet Res 2000;76:135-147.
    • (2000) Genet Res , vol.76 , pp. 135-147
    • Ruvinsky, A.1    Flood, W.D.2    Zhang, T.3    Costantini, F.4
  • 31
    • 0030776825 scopus 로고    scopus 로고
    • Two dominant mutations in the mouse fused gene are the result of transposon insertions
    • Vasicek TJ, Zeng L, Guan XJ, Zhang T, Costantini F, Tilghman SM: Two dominant mutations in the mouse fused gene are the result of transposon insertions. Genetics 1997;147:777-786.
    • (1997) Genetics , vol.147 , pp. 777-786
    • Vasicek, T.J.1    Zeng, L.2    Guan, X.J.3    Zhang, T.4    Costantini, F.5    Tilghman, S.M.6
  • 33
    • 0002671971 scopus 로고
    • The effects of a lethal mutation responsible for duplications and twinning in mouse embryos
    • Gluecksohn-Schoenheimer S: The effects of a lethal mutation responsible for duplications and twinning in mouse embryos. J Exp Zool 1949;110:47-76.
    • (1949) J Exp Zool , vol.110 , pp. 47-76
    • Gluecksohn-Schoenheimer, S.1
  • 34
    • 0021252329 scopus 로고
    • Knobbly, a new dominant mutation in the mouse that affects embryonic ectoderm organization
    • Jacobs-Cohen RJ, Spiegelman M, Cookingham JC, Bennett D: Knobbly, a new dominant mutation in the mouse that affects embryonic ectoderm organization. Genet Res 1984;43:43-50.
    • (1984) Genet Res , vol.43 , pp. 43-50
    • Jacobs-Cohen, R.J.1    Spiegelman, M.2    Cookingham, J.C.3    Bennett, D.4
  • 36
    • 0030029727 scopus 로고    scopus 로고
    • Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family
    • Druey KM, Blumer KJ, Kang VH, Kehrl JH: Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family. Nature 1996;379:742-746.
    • (1996) Nature , vol.379 , pp. 742-746
    • Druey, K.M.1    Blumer, K.J.2    Kang, V.H.3    Kehrl, J.H.4
  • 37
    • 0033813142 scopus 로고    scopus 로고
    • Regulators of G protein signaling: A bestiary of modular protein binding domains
    • Burchett SA: Regulators of G protein signaling: A bestiary of modular protein binding domains. J Neurochem 2000;75:1335-1351.
    • (2000) J Neurochem , vol.75 , pp. 1335-1351
    • Burchett, S.A.1
  • 38
    • 0032473355 scopus 로고    scopus 로고
    • Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin
    • Ikeda S, Kishida S, Yamamoto H, Murai H, Koyama S, Kikuchi A: Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin. EMBO J 1998;17:1371-1384.
    • (1998) EMBO J , vol.17 , pp. 1371-1384
    • Ikeda, S.1    Kishida, S.2    Yamamoto, H.3    Murai, H.4    Koyama, S.5    Kikuchi, A.6
  • 39
    • 0031943002 scopus 로고    scopus 로고
    • Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos
    • Yamamoto H, Kishida S, Uochi T, Ikeda S, Koyama S, Asashima M, Kikuchi A: Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos. Mol Cell Biol 1998;18:2867-2875.
    • (1998) Mol Cell Biol , vol.18 , pp. 2867-2875
    • Yamamoto, H.1    Kishida, S.2    Uochi, T.3    Ikeda, S.4    Koyama, S.5    Asashima, M.6    Kikuchi, A.7
  • 41
    • 0032981560 scopus 로고    scopus 로고
    • Xenopus axin interacts with glycogen synthase kinase-3β and is expressed in the anterior midbrain
    • Hedgepeth CM, Deardorff MA, Klein PS: Xenopus axin interacts with glycogen synthase kinase-3β and is expressed in the anterior midbrain. Mech Dev 1999;80:147-151.
    • (1999) Mech Dev , vol.80 , pp. 147-151
    • Hedgepeth, C.M.1    Deardorff, M.A.2    Klein, P.S.3
  • 44
    • 0034053069 scopus 로고    scopus 로고
    • Wnt signaling in oncogenesis and embryogenesis - A look outside the nucleus
    • Peifer M, Polakis P: Wnt signaling in oncogenesis and embryogenesis - a look outside the nucleus. Science 2000;287:1606-1609.
    • (2000) Science , vol.287 , pp. 1606-1609
    • Peifer, M.1    Polakis, P.2
  • 45
    • 0032539945 scopus 로고    scopus 로고
    • Bridging of β-catenin and glycogen synthase kinase-3β by axin and inhibition of β-catenin-mediated transcription
    • Sakanaka C, Weiss JB, Williams LT: Bridging of β-catenin and glycogen synthase kinase-3β by axin and inhibition of β-catenin- mediated transcription. Proc Natl Acad Sci USA 1998;95:3020-3023.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3020-3023
    • Sakanaka, C.1    Weiss, J.B.2    Williams, L.T.3
  • 46
    • 0033577808 scopus 로고    scopus 로고
    • Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization
    • Fagotto F, Jho E, Zeng L, Kurth T, Joos T, Kaufmann C, Costantini F: Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization. J Cell Biol 1999;145:741-756.
    • (1999) J Cell Biol , vol.145 , pp. 741-756
    • Fagotto, F.1    Jho, E.2    Zeng, L.3    Kurth, T.4    Joos, T.5    Kaufmann, C.6    Costantini, F.7
  • 47
    • 0032841989 scopus 로고    scopus 로고
    • A Drosophila Axin homolog, Daxin, inhibits Wnt signaling
    • Willert K, Logan CY, Arora A, Fish M, Nusse R: A Drosophila Axin homolog, Daxin, inhibits Wnt signaling. Development 1999;126:4165-4173.
    • (1999) Development , vol.126 , pp. 4165-4173
    • Willert, K.1    Logan, C.Y.2    Arora, A.3    Fish, M.4    Nusse, R.5
  • 50
    • 0037309275 scopus 로고    scopus 로고
    • Sequence variants of the Axin gene in hepatoblastoma
    • Miao J, Kusafuka T, Udatsu Y, Okada A: Sequence variants of the Axin gene in hepatoblastoma. Hepatol Res 2003;25:174-179.
    • (2003) Hepatol Res , vol.25 , pp. 174-179
    • Miao, J.1    Kusafuka, T.2    Udatsu, Y.3    Okada, A.4
  • 52
    • 0034720450 scopus 로고    scopus 로고
    • Axin-induced apoptosis depends on the extent of its JNK activation and its ability to down-regulate β-catenin levels
    • Neo SY, Zhang Y, Yaw LP, Li P, Lin SC: Axin-induced apoptosis depends on the extent of its JNK activation and its ability to down-regulate β-catenin levels. Biochem Biophys Res Commun 2000;272:144-150.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 144-150
    • Neo, S.Y.1    Zhang, Y.2    Yaw, L.P.3    Li, P.4    Lin, S.C.5
  • 53
    • 0035842902 scopus 로고    scopus 로고
    • Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice
    • Hsu W, Shakya R, Costantini F: Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice. J Cell Biol 2001;155:1055-1064.
    • (2001) J Cell Biol , vol.155 , pp. 1055-1064
    • Hsu, W.1    Shakya, R.2    Costantini, F.3
  • 54
    • 0033948526 scopus 로고    scopus 로고
    • Sequence variants of the axin gene in breast, colon, and other cancers: An analysis of mutations that interfere with GSK3 binding
    • Webster MT, Rozycka M, Sara E, Davis E, Smalley M, Young N, Dale TC, Wooster R: Sequence variants of the axin gene in breast, colon, and other cancers: An analysis of mutations that interfere with GSK3 binding. Genes Chromosomes Cancer 2000;28:443-453.
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 443-453
    • Webster, M.T.1    Rozycka, M.2    Sara, E.3    Davis, E.4    Smalley, M.5    Young, N.6    Dale, T.C.7    Wooster, R.8
  • 57
    • 0037473082 scopus 로고    scopus 로고
    • AXIN1 mutants but not deletions in cerebellar medulloblastomas
    • Baeza N, Masuoka J, Kleihues P, Ohgaki H: AXIN1 mutants but not deletions in cerebellar medulloblastomas. Oncogene 2003;22:632-636.
    • (2003) Oncogene , vol.22 , pp. 632-636
    • Baeza, N.1    Masuoka, J.2    Kleihues, P.3    Ohgaki, H.4
  • 58
    • 0242268881 scopus 로고    scopus 로고
    • Detection of point mutations of the Axin1 gene in colorectal cancers
    • Jin LH, Shao QJ, Luo W, Ye ZY, Li Q, Lin SC: Detection of point mutations of the Axin1 gene in colorectal cancers. Int J Cancer 2003;107:696-699.
    • (2003) Int J Cancer , vol.107 , pp. 696-699
    • Jin, L.H.1    Shao, Q.J.2    Luo, W.3    Ye, Z.Y.4    Li, Q.5    Lin, S.C.6
  • 59
    • 0035966322 scopus 로고    scopus 로고
    • Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein, Daam1
    • Habas R, Kato Y, He X: Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein, Daam1. Cell 2001;107:843-854.
    • (2001) Cell , vol.107 , pp. 843-854
    • Habas, R.1    Kato, Y.2    He, X.3
  • 60
    • 0034130385 scopus 로고    scopus 로고
    • Xwnt11 is a target of Xenopus Brachyury: Regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway
    • Tada M, Smith JC: Xwnt11 is a target of Xenopus Brachyury: Regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development 2000;127:2227-2238.
    • (2000) Development , vol.127 , pp. 2227-2238
    • Tada, M.1    Smith, J.C.2
  • 62
    • 0032516178 scopus 로고    scopus 로고
    • Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila
    • Gho M, Schweisguth F: Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila. Nature 1998;393:178-181.
    • (1998) Nature , vol.393 , pp. 178-181
    • Gho, M.1    Schweisguth, F.2
  • 63
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: A common theme in animal development
    • Cadigan KM, Nusse R: Wnt signaling: A common theme in animal development. Genes Dev 1997;11:3286-3305.
    • (1997) Genes Dev , vol.11 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 65
    • 0027401529 scopus 로고
    • Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus
    • Christian JL, Moon RT: Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus. Genes Dev 1993;7:13-28.
    • (1993) Genes Dev , vol.7 , pp. 13-28
    • Christian, J.L.1    Moon, R.T.2
  • 66
    • 0022485392 scopus 로고
    • Genetic analysis of mutations at the fused locus in the mouse
    • Greenspan RJ, O'Brien MC: Genetic analysis of mutations at the fused locus in the mouse. Proc Natl Acad Sci USA 1986;83:4413-4417.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4413-4417
    • Greenspan, R.J.1    O'Brien, M.C.2
  • 67
    • 0034657187 scopus 로고    scopus 로고
    • Structural basis of the axin-adenomatous polyposis coli interaction
    • Spink KE, Polakis P, Weis WI: Structural basis of the axin-adenomatous polyposis coli interaction. EMBO J 2000;19:2270-2279.
    • (2000) EMBO J , vol.19 , pp. 2270-2279
    • Spink, K.E.1    Polakis, P.2    Weis, W.I.3
  • 68
    • 0037416148 scopus 로고    scopus 로고
    • Nuclear export of the APC tumor suppressor controls beta-catenin function in transcription
    • Rosin-Arbesfeld R, Cliffe A, Brabletz T, Bienz M: Nuclear export of the APC tumor suppressor controls beta-catenin function in transcription. EMBO J 2003;22:1101-1113.
    • (2003) EMBO J , vol.22 , pp. 1101-1113
    • Rosin-Arbesfeld, R.1    Cliffe, A.2    Brabletz, T.3    Bienz, M.4
  • 69
    • 0036747385 scopus 로고    scopus 로고
    • The ins and outs of APC and beta-catenin nuclear transport
    • Henderson BR, Fagotto F: The ins and outs of APC and beta-catenin nuclear transport. EMBO Rep 2002;3:834-839.
    • (2002) EMBO Rep , vol.3 , pp. 834-839
    • Henderson, B.R.1    Fagotto, F.2
  • 70
    • 0032568802 scopus 로고    scopus 로고
    • Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development
    • Ahmed Y, Hayashi S, Levine A, Wieschaus E: Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development. Cell 1998;93:1171-1182.
    • (1998) Cell , vol.93 , pp. 1171-1182
    • Ahmed, Y.1    Hayashi, S.2    Levine, A.3    Wieschaus, E.4
  • 71
    • 0034602160 scopus 로고    scopus 로고
    • Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3β-dependent phosphorylation of beta-catenin and down-regulates beta-catenin
    • Hinoi T, Yamamoto H, Kishida M, Takada S, Kishida S, Kikuchi A: Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3β-dependent phosphorylation of beta-catenin and down-regulates beta-catenin. J Biol Chem 2000;275:34399-34406.
    • (2000) J Biol Chem , vol.275 , pp. 34399-34406
    • Hinoi, T.1    Yamamoto, H.2    Kishida, M.3    Takada, S.4    Kishida, S.5    Kikuchi, A.6
  • 72
    • 0034708763 scopus 로고    scopus 로고
    • Down-regulation of beta-catenin by the colorectal tumor suppressor APC requires association with Axin and β-catenin
    • Kawahara K, Morishita T, Nakamura T, Hamada F, Toyoshima K, Akiyama T: Down-regulation of beta-catenin by the colorectal tumor suppressor APC requires association with Axin and β-catenin. J Biol Chem 2000;275:8369-8374.
    • (2000) J Biol Chem , vol.275 , pp. 8369-8374
    • Kawahara, K.1    Morishita, T.2    Nakamura, T.3    Hamada, F.4    Toyoshima, K.5    Akiyama, T.6
  • 73
    • 0030871048 scopus 로고    scopus 로고
    • Loss of beta-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene
    • Rubinfeld B, Albert I, Porfiri E, Munemitsu S, Polakis P: Loss of beta-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene. Cancer Res 1997;57:4624-4630.
    • (1997) Cancer Res , vol.57 , pp. 4624-4630
    • Rubinfeld, B.1    Albert, I.2    Porfiri, E.3    Munemitsu, S.4    Polakis, P.5
  • 74
    • 0032493042 scopus 로고    scopus 로고
    • Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin
    • Itoh K, Krupnik VE, Sokol SY: Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin. Curr Biol 1998;8:591-594.
    • (1998) Curr Biol , vol.8 , pp. 591-594
    • Itoh, K.1    Krupnik, V.E.2    Sokol, S.Y.3
  • 75
    • 0036629249 scopus 로고    scopus 로고
    • Wnt signal transduction: Kinase cogs in a nano-machine?
    • Ding Y, Dale T: Wnt signal transduction: Kinase cogs in a nano-machine? Trends Biochem Sci 2002;27:327-329.
    • (2002) Trends Biochem Sci , vol.27 , pp. 327-329
    • Ding, Y.1    Dale, T.2
  • 76
    • 0037415737 scopus 로고    scopus 로고
    • Structural basis for recruitment of glycogen synthase kinase 3β to the axin-APC scaffold complex
    • Dajani R, Fraser E, Roe SM, Yeo M, Good VM, Thompson V, Dale TC, Pearl LH: Structural basis for recruitment of glycogen synthase kinase 3β to the axin-APC scaffold complex. EMBO J 2003;22:494-501.
    • (2003) EMBO J , vol.22 , pp. 494-501
    • Dajani, R.1    Fraser, E.2    Roe, S.M.3    Yeo, M.4    Good, V.M.5    Thompson, V.6    Dale, T.C.7    Pearl, L.H.8
  • 79
    • 0029664368 scopus 로고    scopus 로고
    • Binding of GSK-3β to the APC-β-catenin complex and regulation of complex assembly
    • Rubinfeld B, Albert I, Porfiri E, Fiol C, Munemitsu S, Polakis P: Binding of GSK-3β to the APC-β-catenin complex and regulation of complex assembly. Science 1996;272:1023-1026.
    • (1996) Science , vol.272 , pp. 1023-1026
    • Rubinfeld, B.1    Albert, I.2    Porfiri, E.3    Fiol, C.4    Munemitsu, S.5    Polakis, P.6
  • 80
    • 0037348372 scopus 로고    scopus 로고
    • A novel viral mechanism for dysregulation of β-catenin in Kaposi's sarcoma-associated herpesvirus latency
    • Fujimuro M, Wu FY, ApRhys C, Kajumbula H, Young DB, Hayward GS, Hayward SD: A novel viral mechanism for dysregulation of β-catenin in Kaposi's sarcoma-associated herpesvirus latency. Nat Med 2003;9:300-306.
    • (2003) Nat Med , vol.9 , pp. 300-306
    • Fujimuro, M.1    Wu, F.Y.2    ApRhys, C.3    Kajumbula, H.4    Young, D.B.5    Hayward, G.S.6    Hayward, S.D.7
  • 81
    • 0037155691 scopus 로고    scopus 로고
    • Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
    • Liu C, Li Y, Semenov M, Han C, Baeg GH, Tan Y, Zhang Z, Lin X, He X: Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 2002;108:837-847.
    • (2002) Cell , vol.108 , pp. 837-847
    • Liu, C.1    Li, Y.2    Semenov, M.3    Han, C.4    Baeg, G.H.5    Tan, Y.6    Zhang, Z.7    Lin, X.8    He, X.9
  • 82
    • 0027723788 scopus 로고
    • Catenins as mediators of the cytoplasmic functions of cadherins
    • Gumbiner BM, McCrea PD: Catenins as mediators of the cytoplasmic functions of cadherins. J Cell Sci Suppl 1993;17:155-158.
    • (1993) J Cell Sci Suppl , vol.17 , pp. 155-158
    • Gumbiner, B.M.1    McCrea, P.D.2
  • 83
    • 0027302657 scopus 로고
    • Catenins in Xenopus embryogenesis and their relation to the cadherin-mediated cell-cell adhesion system
    • Schneider S, Herrenknecht K, Butz S, Kemler R, Hausen P: Catenins in Xenopus embryogenesis and their relation to the cadherin-mediated cell-cell adhesion system. Development 1993;118:629-640.
    • (1993) Development , vol.118 , pp. 629-640
    • Schneider, S.1    Herrenknecht, K.2    Butz, S.3    Kemler, R.4    Hausen, P.5
  • 84
    • 0035797897 scopus 로고    scopus 로고
    • Adhesion signaling: How β-catenin interacts with its partners
    • Gottardi CJ, Gumbiner BM: Adhesion signaling: How β-catenin interacts with its partners. Curr Biol 2001;11:R792-R794.
    • (2001) Curr Biol , vol.11
    • Gottardi, C.J.1    Gumbiner, B.M.2
  • 86
    • 0028982101 scopus 로고
    • Signal transduction of beta-catenin
    • Gumbiner BM: Signal transduction of beta-catenin. Curr Opin Cell Biol 1995;7:634-640.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 634-640
    • Gumbiner, B.M.1
  • 87
    • 0027860462 scopus 로고
    • A model system for cell adhesion and signal transduction in Drosophila
    • Peifer M, Orsulic S, Pai LM, Loureiro J: A model system for cell adhesion and signal transduction in Drosophila. Dev Suppl 1993:163-176.
    • (1993) Dev Suppl , pp. 163-176
    • Peifer, M.1    Orsulic, S.2    Pai, L.M.3    Loureiro, J.4
  • 88
    • 0029920839 scopus 로고    scopus 로고
    • Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes
    • Papkoff J, Rubinfeld B, Schryver B, Polakis P: Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes. Mol Cell Biol 1996;16:2128-2134.
    • (1996) Mol Cell Biol , vol.16 , pp. 2128-2134
    • Papkoff, J.1    Rubinfeld, B.2    Schryver, B.3    Polakis, P.4
  • 89
    • 0028047389 scopus 로고
    • Wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo
    • Peifer M, Sweeton D, Casey M, Wieschaus E: Wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo. Development 1994;120:369-380.
    • (1994) Development , vol.120 , pp. 369-380
    • Peifer, M.1    Sweeton, D.2    Casey, M.3    Wieschaus, E.4
  • 90
    • 0030978351 scopus 로고    scopus 로고
    • β-Catenin is a target for the ubiquitin-proteasome pathway
    • Aberle HA, Bauer A, Stappert J, Kispert A, Kemler R: β-Catenin is a target for the ubiquitin-proteasome pathway. EMBO J 1997;16:3797-3804.
    • (1997) EMBO J , vol.16 , pp. 3797-3804
    • Aberle, H.A.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 91
    • 0030930442 scopus 로고    scopus 로고
    • A β-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus
    • Brannon M, Gomperts M, Sumoy L, Moon RT, Kimelman D: A β-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus. Genes Dev 1997;11:2359-2370.
    • (1997) Genes Dev , vol.11 , pp. 2359-2370
    • Brannon, M.1    Gomperts, M.2    Sumoy, L.3    Moon, R.T.4    Kimelman, D.5
  • 92
    • 0031453354 scopus 로고    scopus 로고
    • The Xenopus homeobox gene twin mediates Wnt induction of goosecoid in establishment of Spemann's organizer
    • Laurent MN, Blitz IL, Hashimoto C, Rothbacher U, Cho KW: The Xenopus homeobox gene twin mediates Wnt induction of goosecoid in establishment of Spemann's organizer. Development 1997;124:4905-4916.
    • (1997) Development , vol.124 , pp. 4905-4916
    • Laurent, M.N.1    Blitz, I.L.2    Hashimoto, C.3    Rothbacher, U.4    Cho, K.W.5
  • 94
    • 18744425721 scopus 로고    scopus 로고
    • LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter
    • McKendry R, Hsu SC, Harland RM, Grosschedl R: LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter. Dev Biol 1997;192:420-431.
    • (1997) Dev Biol , vol.192 , pp. 420-431
    • McKendry, R.1    Hsu, S.C.2    Harland, R.M.3    Grosschedl, R.4
  • 95
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O, McCormick F: Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999;398:422-426.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 97
    • 0033605639 scopus 로고    scopus 로고
    • Regulation of β-catenin signaling by the B56 subunit of protein phosphatase 2A
    • Seeling JM, Miller JR, Gil R, Moon RT, White R, Virshup DM: Regulation of β-catenin signaling by the B56 subunit of protein phosphatase 2A. Science 1999;283:2089-2091.
    • (1999) Science , vol.283 , pp. 2089-2091
    • Seeling, J.M.1    Miller, J.R.2    Gil, R.3    Moon, R.T.4    White, R.5    Virshup, D.M.6
  • 98
    • 0034719170 scopus 로고    scopus 로고
    • GSK-3β-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by β-catenin and protein phosphatase 2A complexed with Axin
    • Ikeda S, Kishida M, Matsuura Y, Usui H, Kikuchi A: GSK-3β-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by β-catenin and protein phosphatase 2A complexed with Axin. Oncogene 2000;19:537-545.
    • (2000) Oncogene , vol.19 , pp. 537-545
    • Ikeda, S.1    Kishida, M.2    Matsuura, Y.3    Usui, H.4    Kikuchi, A.5
  • 99
    • 0034680788 scopus 로고    scopus 로고
    • A positive role for the PP2A catalytic subunit in Wnt signal transduction
    • Ratcliffe MJ, Itoh K, Sokol SY: A positive role for the PP2A catalytic subunit in Wnt signal transduction. J Biol Chem 2000;275:35680-35683.
    • (2000) J Biol Chem , vol.275 , pp. 35680-35683
    • Ratcliffe, M.J.1    Itoh, K.2    Sokol, S.Y.3
  • 101
    • 0035423033 scopus 로고    scopus 로고
    • Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus
    • Li X, Yost HJ, Virshup DM, Seeling JM: Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus. EMBO J 2001;20:4122-4131.
    • (2001) EMBO J , vol.20 , pp. 4122-4131
    • Li, X.1    Yost, H.J.2    Virshup, D.M.3    Seeling, J.M.4
  • 103
    • 0029036113 scopus 로고
    • Isolation and characterization of human casein kinase I epsilon (CKIε), a novel member of the CKI gene family
    • Fish KJ, Cegielska A, Getman ME, Landes GM, Virshup DM: Isolation and characterization of human casein kinase I epsilon (CKIε), a novel member of the CKI gene family. J Biol Chem 1995;270:14875-14883.
    • (1995) J Biol Chem , vol.270 , pp. 14875-14883
    • Fish, K.J.1    Cegielska, A.2    Getman, M.E.3    Landes, G.M.4    Virshup, D.M.5
  • 104
    • 0034045931 scopus 로고    scopus 로고
    • Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon
    • Vielhaber E, Eide E, Rivers A, Gao ZH, Virshup DM: Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon. Mol Cell Biol 2000;20:4888-4899.
    • (2000) Mol Cell Biol , vol.20 , pp. 4888-4899
    • Vielhaber, E.1    Eide, E.2    Rivers, A.3    Gao, Z.H.4    Virshup, D.M.5
  • 106
    • 0037162282 scopus 로고    scopus 로고
    • Casein kinase 1: A Wnt'er of disconnect
    • Polakis P: Casein kinase 1: A Wnt'er of disconnect. Curr Biol 2002;12:R499-R501.
    • (2002) Curr Biol , vol.12
    • Polakis, P.1
  • 109
    • 0037022275 scopus 로고    scopus 로고
    • Casein kinase I phosphorylates and destabilizes the β-catenin degradation complex
    • Gao ZH, Seeling JM, Hill V, Yochum A, Virshup DM: Casein kinase I phosphorylates and destabilizes the β-catenin degradation complex. Proc Natl Acad Sci USA 2002;99:1182-1187.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 1182-1187
    • Gao, Z.H.1    Seeling, J.M.2    Hill, V.3    Yochum, A.4    Virshup, D.M.5
  • 110
    • 0037900076 scopus 로고    scopus 로고
    • Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin
    • Hino S, Michiue T, Asashima M, Kikuchi A: Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin. J Biol Chem 2003;278:14066-14073.
    • (2003) J Biol Chem , vol.278 , pp. 14066-14073
    • Hino, S.1    Michiue, T.2    Asashima, M.3    Kikuchi, A.4
  • 111
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P: Wnt signaling and cancer. Genes Dev 2000;14:1837-1851.
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 113
    • 0027944513 scopus 로고
    • Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled
    • Sussman DJ, Klingensmith J, Salinas P, Adams PS, Nusse R, Perrimon N: Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled. Dev Biol 1994;166:73-86.
    • (1994) Dev Biol , vol.166 , pp. 73-86
    • Sussman, D.J.1    Klingensmith, J.2    Salinas, P.3    Adams, P.S.4    Nusse, R.5    Perrimon, N.6
  • 114
    • 0030973456 scopus 로고    scopus 로고
    • Casein kinase 2 associates with and phosphorylates dishevelled
    • Willert K, Brink M, Wodarz A, Varmus H, Nusse R: Casein kinase 2 associates with and phosphorylates dishevelled. EMBO J 1997;16:3089-3096.
    • (1997) EMBO J , vol.16 , pp. 3089-3096
    • Willert, K.1    Brink, M.2    Wodarz, A.3    Varmus, H.4    Nusse, R.5
  • 115
    • 0031024689 scopus 로고    scopus 로고
    • Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas
    • Jonkers J, Korswagen HC, Acton D, Breuer M, Berns A: Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas. EMBO J 1997;16:441-450.
    • (1997) EMBO J , vol.16 , pp. 441-450
    • Jonkers, J.1    Korswagen, H.C.2    Acton, D.3    Breuer, M.4    Berns, A.5
  • 117
    • 0038558190 scopus 로고    scopus 로고
    • Sumoylation is involved in β-catenin-dependent activation of Tcf-4
    • Yamamoto H, Ihara M, Matsuura Y, Kikuchi A: Sumoylation is involved in β-catenin-dependent activation of Tcf-4. EMBO J 2003;22:2047-2059.
    • (2003) EMBO J , vol.22 , pp. 2047-2059
    • Yamamoto, H.1    Ihara, M.2    Matsuura, Y.3    Kikuchi, A.4
  • 118
    • 0034836428 scopus 로고    scopus 로고
    • LRP: A multifunctional scavenger and signaling receptor
    • Herz J, Strickland DK: LRP: A multifunctional scavenger and signaling receptor. J Clin Invest 2001;108:779-784.
    • (2001) J Clin Invest , vol.108 , pp. 779-784
    • Herz, J.1    Strickland, D.K.2
  • 119
  • 122
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson GL, Lapadat R: Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002;298:1911-1912.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 123
    • 0035212589 scopus 로고    scopus 로고
    • The ups and downs of MEK kinase interactions
    • Hagemann C, Blank JL: The ups and downs of MEK kinase interactions. Cell Signal 2001;13:863-875.
    • (2001) Cell Signal , vol.13 , pp. 863-875
    • Hagemann, C.1    Blank, J.L.2
  • 124
    • 0037022564 scopus 로고    scopus 로고
    • Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity
    • Schmidt D, Müller S: Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity. Proc Natl Acad Sci USA 2002;99:2872-2877.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2872-2877
    • Schmidt, D.1    Müller, S.2
  • 126
    • 0035799530 scopus 로고    scopus 로고
    • Functional analysis and intracellular localization of p53 modified by SUMO-1
    • Kwek SS, Derry J, Tyner AL, Shen Z, Gudkov AV: Functional analysis and intracellular localization of p53 modified by SUMO-1. Oncogene 2001;20:2587-2599.
    • (2001) Oncogene , vol.20 , pp. 2587-2599
    • Kwek, S.S.1    Derry, J.2    Tyner, A.L.3    Shen, Z.4    Gudkov, A.V.5
  • 128
    • 0037295721 scopus 로고    scopus 로고
    • Modification with SUMO: A role in transcriptional regulation
    • Verger A, Perdomo J, Crossley M: Modification with SUMO: A role in transcriptional regulation. EMBO Rep 2003;4:137-142.
    • (2003) EMBO Rep , vol.4 , pp. 137-142
    • Verger, A.1    Perdomo, J.2    Crossley, M.3
  • 129
    • 0031106404 scopus 로고    scopus 로고
    • Transforming growth factor-beta: Vasculogenesis, angiogenesis, and vessel wall integrity
    • Pepper MS: Transforming growth factor-beta: Vasculogenesis, angiogenesis, and vessel wall integrity. Cytokine Growth Factor Rev 1997;8:21-43.
    • (1997) Cytokine Growth Factor Rev , vol.8 , pp. 21-43
    • Pepper, M.S.1
  • 131
    • 0034034802 scopus 로고    scopus 로고
    • Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina
    • Birgbauer E, Cowan CA, Sretavan DW, Henkemeyer M: Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development 2000;127:1231-1241.
    • (2000) Development , vol.127 , pp. 1231-1241
    • Birgbauer, E.1    Cowan, C.A.2    Sretavan, D.W.3    Henkemeyer, M.4
  • 133
    • 0037414439 scopus 로고    scopus 로고
    • Axin and Axin/Arrow-binding protein DCAP mediate glucose-glycogen metabolism
    • Yamazaki H, Yanagawa S: Axin and Axin/Arrow-binding protein DCAP mediate glucose-glycogen metabolism. Biochem Biophys Res Commun 2003;304:229-235.
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 229-235
    • Yamazaki, H.1    Yanagawa, S.2


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