Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes

Molecular and Cellular Biology

Volumn 16, Issue 5, 1996, Pages 2128-2134

  Papkoff, Jackie ^a,c   Rubinfeld, Bonnee ^b   Schryver, Brian ^a   Polakis, Paul ^b  

^a SUGEN INC   (United States)

^b ONYX PHARMACEUTICALS   (United States)

^c Megabios Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APC; CATENIN; PLAKOGLOBIN;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; GENE EXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0029920839     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.5.2128     Document Type: Article

References (31)

1. Aberle, H., S. Butz, J. Stappert, H. Weissig, R. Kemler, and H. Hoschuetzky. 1994. Assembly of the cadherin catenin complex in vitro with recombinant proteins. J. Cell Sci. 107:3655-3663.
2. Blasband, A., B. Schryver, and J. Papkoff. 1992 The biochemical properties and transforming potential of human Wnt-2 are similar to Wnt-1. Oncogene 7:153-161.
3. Bradley, R. S., and A. M. C. Brown. 1990. The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix. EMBO J 9: 1569-1575.
4. Bradley, R. S., P. Cowin, and A. M. C. Brown. 1993. Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. J. Cell Biol 123:1857-1865.
5. Eldar-Finkelman, H., R. Seger, Vandenheede, and E. G. Krebs. 1995. Inactivation of glycogen synthase kinase-3 by epidermal growth factor is mediated by mitogen-activated protein kinase/p90 ribosomal S6 kinase signaling pathway in NIH/3T3 cells J. Biol. Chem. 270:987-990.
6. Forsayeth, J. R., and P. D. Garcia. 1994. Adenovirus-mediated transfection of cultured cells. Biotechniques 17:354-359
7. Funayama, N., F. Fagotto, P. McCrea, and B. M. Gumbiner. 1995. Embryonic axis induction by the armadillo repeat domain of β-catenin: evidence for intracellular signaling. J. Cell Biol. 128:959-968
8. He, X., J. P. Saint-Jeannet, J. R. Woodgett, H. E. Varmus, and I. B. Dawid. 1995. Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature (London) 374:617-623.
9. Hinck, L., W. J. Nelson, and J. Papkoff. 1994. Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing β-catenin binding to the cell adhesion protein cadherin. J Cell Biol. 124:729-741
10. Hoschuetzky, H., H. Aberle, and R. Kemler. 1994. β-Catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor. J. Cell Biol. 127:1375-1380
11. Hulsken, J., W. Birchmeier, and J. Behrens. 1995. E-cadherin and APC compete for the interaction of p-catenin with the cytoskeleton. J. Cell Biol. 127:2061-2069.
12. Karnovsky, A., and M. W. Klymkowsky. 1995. Anterior axis duplication in Xenopus induced by the over-expression of the catenin-binding protein plakoglobin. Proc. Natl. Acad. Sci. USA 92:4522-4526.
13. McCrea, P. D., C. W. Turck, and B. Gumbiner. 1991. A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. Science 254:1359-1361.
14. McMahon, A. P., and R. T. Moon. 1989. Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis. Cell 58:1075-1084.
15. Munemitsu, S., I. Albert, B. Souza, B. Rubinfeld, and P. Polakis. 1995. Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc. Natl. Acad. Sci. USA 92:3046-3050
16. Nagafuchi, A., and M. Takeichi. 1988. Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J. 7:3679-3684.
17. Nusse, R., and H. E. Varmus. 1992. Wnt genes. Cell 69:1073-1087.
18. Ozawa, M., H. Baribault, and R. Kemler. 1989. The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J. 8:1711-1717.
19. Ozawa, M., M. Ringwald, and R. Kemler. 1990. Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule Proc Natl Acad. Sci. USA 87:4246-4250.
20. Papkoff, J., and B. Schryver. 1990 Secreted int-1 protein is associated with the cell surface. Mol. Cell. Biol. 10:2723-2730.
21. Peifer, M. 1993. Cancer, catenins, and cuticle pattern: a complex connection. Science 262:1667-1668.
22. Peifer, M. 1995. Cell adhesion and signal transduction: the armadillo connection Trends Cell Biol. 5:224-229.
23. Peifer, M., D. Sweeton, M. Casey, and E. Wieschus. 1994. wingless and zeste-white 3 kinase trigger opposing changes in the intracellular distribution of armadillo. Development 120:369-380.
24. Polakis, P. 1995. Mutations in the APC gene and their implications for protein structure and function. Curr Opin. Genet. Dev. 5:66-71.
25. rap1 Cell 65:1033-1042.
26. Rubinfeld, B., B. Souza, I. Albert, O. Muller, S. C. Chamberlain, F. Masiarz, S. Munemitsu, and P. Polakis. 1993. Association of the APC gene product with β-catenin. Science 262:1731-1734.
27. Rubinfeld, B. R., B. Souza, I. Albert, S. Munemitsu, and P. Polakis. 1995. The APC protein and E-cadherin form similar but independent complexes with α-catenin, β-catenin, and plakoglobin. J Biol. Chem. 270:5549-5555.
28. Smolich, B. D., J. A. McMahon, A. P. McMahon, and J. Papkoff. 1993. Wnt family proteins are secreted and associated with the cell surface. Mol Biol. Cell 4:1267-1275.
29. Su, L.-K., B. Vogelstein, and K. W. Kinzler. 1993 Association of the APC tumor suppressor protein with catenins. Science 262:1734-1737.
30. van Leeuwen, F., C. H. Samos, and R. Nusse. 1994 Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells Nature (London) 368:342-344.
31. Whitehead, I., H. Kirk, and R. Kay. 1995. Expression cloning of oncogenes by retroviral transfer of cDNA libraries. Mol. Cell. Biol. 15:704-710.