-
1
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, et al. (2003) Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423: 448-452.
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
Duncan, A.W.4
Weissman, I.L.5
-
2
-
-
0037737728
-
A role for Wnt signaling in self-renewal of haematopoietic stem cells
-
Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, et al. (2003) A role for Wnt signaling in self-renewal of haematopoietic stem cells. Nature 423: 409-414.
-
(2003)
Nature
, vol.423
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
Domen, J.4
Scherer, D.C.5
-
3
-
-
34247140309
-
Wnt signaling promotes regeneration in the retina of adult mammals
-
Osakada F, Ooto S, Akagi T, Mandai M, Akaike A, et al. (2007) Wnt signaling promotes regeneration in the retina of adult mammals. J Neurosci 27: 4210-4219.
-
(2007)
J Neurosci
, vol.27
, pp. 4210-4219
-
-
Osakada, F.1
Ooto, S.2
Akagi, T.3
Mandai, M.4
Akaike, A.5
-
4
-
-
34250627652
-
-
Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, et al. (2007) Small-molecule synergist of the Wnt/{beta}-catenin signaling pathway. Proc Natl Acad Sci U S A.
-
Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, et al. (2007) Small-molecule synergist of the Wnt/{beta}-catenin signaling pathway. Proc Natl Acad Sci U S A.
-
-
-
-
5
-
-
16844364003
-
A small-molecule agonist of the Wnt signaling pathway
-
Liu J, Wu X, Mitchell B, Kintner C, Ding S, et al. (2005) A small-molecule agonist of the Wnt signaling pathway. Angew Chem Int Ed Engl 44: 1987-1990.
-
(2005)
Angew Chem Int Ed Engl
, vol.44
, pp. 1987-1990
-
-
Liu, J.1
Wu, X.2
Mitchell, B.3
Kintner, C.4
Ding, S.5
-
6
-
-
28244496603
-
Identification of a specific inhibitor of the dishevelled PDZ domain
-
Shan J, Shi DL, Wang J, Zheng J (2005) Identification of a specific inhibitor of the dishevelled PDZ domain. Biochemistry 44: 15495-15503.
-
(2005)
Biochemistry
, vol.44
, pp. 15495-15503
-
-
Shan, J.1
Shi, D.L.2
Wang, J.3
Zheng, J.4
-
7
-
-
4344619713
-
Pharmacological inhibitors of glycogen synthase kinase 3
-
Meijer L, Flajolet M, Greengard P (2004) Pharmacological inhibitors of glycogen synthase kinase 3. Trends Pharmacol Sci 25: 471-480.
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 471-480
-
-
Meijer, L.1
Flajolet, M.2
Greengard, P.3
-
8
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya T, Clevers H (2005) Wnt signalling in stem cells and cancer. Nature 434: 843-850.
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
9
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H (2006) Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
10
-
-
33847199795
-
Wnt signaling and human diseases: What are the therapeutic implications?
-
Luo J, Chen J, Deng ZL, Luo X, Song WX, et al. (2007) Wnt signaling and human diseases: what are the therapeutic implications? Lab Invest 87: 97-103.
-
(2007)
Lab Invest
, vol.87
, pp. 97-103
-
-
Luo, J.1
Chen, J.2
Deng, Z.L.3
Luo, X.4
Song, W.X.5
-
11
-
-
33751318469
-
Monounsaturated fatty acid modification of Wnt protein: Its role in Wnt secretion
-
Takada R, Satomi Y, Kurata T, Ueno N, Norioka S, et al. (2006) Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion. Dev Cell 11: 791-801.
-
(2006)
Dev Cell
, vol.11
, pp. 791-801
-
-
Takada, R.1
Satomi, Y.2
Kurata, T.3
Ueno, N.4
Norioka, S.5
-
12
-
-
0035384770
-
Liposomes: Applications in medicine
-
Banerjee R (2001) Liposomes: applications in medicine. J Biomater Appl 16: 3-21.
-
(2001)
J Biomater Appl
, vol.16
, pp. 3-21
-
-
Banerjee, R.1
-
13
-
-
0034801725
-
Liposome-encapsulated aminoglycosides in pre-clinical and clinical studies
-
Schiffelers R, Storm G, Bakker-Woudenberg I (2001) Liposome-encapsulated aminoglycosides in pre-clinical and clinical studies. J Antimicrob Chemother 48: 333-344.
-
(2001)
J Antimicrob Chemother
, vol.48
, pp. 333-344
-
-
Schiffelers, R.1
Storm, G.2
Bakker-Woudenberg, I.3
-
14
-
-
11244317232
-
From conventional to stealth liposomes: A new Frontier in cancer chemotherapy
-
Cattel L, Ceruti M, Dosio F (2004) From conventional to stealth liposomes: a new Frontier in cancer chemotherapy. J Chemother 16 Suppl 4: 94-97.
-
(2004)
J Chemother
, vol.16
, Issue.SUPPL. 4
, pp. 94-97
-
-
Cattel, L.1
Ceruti, M.2
Dosio, F.3
-
15
-
-
0036096806
-
Liposome-based drug delivery in breast cancer treatment
-
Park JW (2002) Liposome-based drug delivery in breast cancer treatment. Breast Cancer Res 4: 95-99.
-
(2002)
Breast Cancer Res
, vol.4
, pp. 95-99
-
-
Park, J.W.1
-
16
-
-
33646381864
-
Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis
-
Koning GA, Schiffelers RM, Wauben MR, Kok RJ, Mastrobattista E, et al. (2006) Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis. Arthritis Rheum 54: 1198-1208.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1198-1208
-
-
Koning, G.A.1
Schiffelers, R.M.2
Wauben, M.R.3
Kok, R.J.4
Mastrobattista, E.5
-
18
-
-
0035981024
-
The development and testing of a new temperature-sensitive drug deliverY system for the treatment of solid tumors
-
Needham D, Dewhirst MW (2001) The development and testing of a new temperature-sensitive drug deliverY system for the treatment of solid tumors. Adv Drug Deliv Rev 53: 285-305.
-
(2001)
Adv Drug Deliv Rev
, vol.53
, pp. 285-305
-
-
Needham, D.1
Dewhirst, M.W.2
-
19
-
-
34347254641
-
The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
-
DeAlmeida VI, Miao L, Ernst JA, Koeppen H, Polakis P, et al. (2007) The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo. Cancer Res 67: 5371-5379.
-
(2007)
Cancer Res
, vol.67
, pp. 5371-5379
-
-
DeAlmeida, V.I.1
Miao, L.2
Ernst, J.A.3
Koeppen, H.4
Polakis, P.5
-
20
-
-
33646241997
-
Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
-
Mikels AJ, Nusse R (2006) Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol 4: e115.
-
(2006)
PLoS Biol
, vol.4
-
-
Mikels, A.J.1
Nusse, R.2
-
21
-
-
4043154959
-
Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine
-
Zhai L, Chaturvedi D, Cumberledge S (2004) Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine. J Biol Chem 279: 33220-33227.
-
(2004)
J Biol Chem
, vol.279
, pp. 33220-33227
-
-
Zhai, L.1
Chaturvedi, D.2
Cumberledge, S.3
-
22
-
-
0035823004
-
Argosomes: A potential vehicle for the spread of morphogens through epithelia
-
Greco V, Hannus M, Eaton S (2001) Argosomes: a potential vehicle for the spread of morphogens through epithelia. Cell 106: 633-645.
-
(2001)
Cell
, vol.106
, pp. 633-645
-
-
Greco, V.1
Hannus, M.2
Eaton, S.3
-
23
-
-
18344378499
-
Lipoprotein particles are required for Hedgehog and Wingless signalling
-
Panakova D, Sprong H, Marois E, Thiele C, Eaton S (2005) Lipoprotein particles are required for Hedgehog and Wingless signalling. Nature 435: 58-65.
-
(2005)
Nature
, vol.435
, pp. 58-65
-
-
Panakova, D.1
Sprong, H.2
Marois, E.3
Thiele, C.4
Eaton, S.5
-
24
-
-
34249106502
-
Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding
-
Ito M, Yang Z, Andl T, Cui C, Kim N, et al. (2007) Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding. Nature 447: 316-320.
-
(2007)
Nature
, vol.447
, pp. 316-320
-
-
Ito, M.1
Yang, Z.2
Andl, T.3
Cui, C.4
Kim, N.5
-
25
-
-
0036148208
-
Wnt/ beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
-
Jho EH, Zhang T, Domon C, Joo CK, Freund JN, et al. (2002) Wnt/ beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol 22: 1172-1183.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1172-1183
-
-
Jho, E.H.1
Zhang, T.2
Domon, C.3
Joo, C.K.4
Freund, J.N.5
-
26
-
-
0036149985
-
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors
-
Lustig B, Jerchow B, Sachs M, Weiler S, Pietsch T, et al. (2002) Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Moll Cell Biol 22: 1184-1193.
-
(2002)
Moll Cell Biol
, vol.22
, pp. 1184-1193
-
-
Lustig, B.1
Jerchow, B.2
Sachs, M.3
Weiler, S.4
Pietsch, T.5
-
27
-
-
0344464720
-
Wnts and Hedgehogs: Lipid-modified proteins and similarities in signaling mechanisms at the cell surface
-
Nusse R (2003) Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface. Development 130: 5297-5305.
-
(2003)
Development
, vol.130
, pp. 5297-5305
-
-
Nusse, R.1
-
28
-
-
2942742564
-
Novel lipid modifications of secreted protein signals
-
Mann RK, Beachy PA (2004) Novel lipid modifications of secreted protein signals. Annu Rev Biochem 73: 891-923.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 891-923
-
-
Mann, R.K.1
Beachy, P.A.2
-
29
-
-
0027368963
-
Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein
-
van den Heuvel M, Harryman-Samos C, Klingensmith J, Perrimon N, Nusse R (1993) Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. Embo J 12: 5293-5302.
-
(1993)
Embo J
, vol.12
, pp. 5293-5302
-
-
van den Heuvel, M.1
Harryman-Samos, C.2
Klingensmith, J.3
Perrimon, N.4
Nusse, R.5
-
30
-
-
0030450052
-
The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing
-
Kadowaki T, Wilder E, Klingensmith J, Zachary K, Perrimon N (1996) The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes Dev 10: 3116-3128.
-
(1996)
Genes Dev
, vol.10
, pp. 3116-3128
-
-
Kadowaki, T.1
Wilder, E.2
Klingensmith, J.3
Zachary, K.4
Perrimon, N.5
-
31
-
-
31744439979
-
Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion
-
Miura GI, Buglino J, Alvarado D, Lemmon MA, Resh MD, et al. (2006) Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion. Dev Cell 10: 167-176.
-
(2006)
Dev Cell
, vol.10
, pp. 167-176
-
-
Miura, G.I.1
Buglino, J.2
Alvarado, D.3
Lemmon, M.A.4
Resh, M.D.5
-
32
-
-
21344436821
-
Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells
-
Silva-Vargas V, Lo Celso C, Giangreco A, Ofstad T, Prowse DM, et al. (2005) Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. Dev Cell 9: 121-131.
-
(2005)
Dev Cell
, vol.9
, pp. 121-131
-
-
Silva-Vargas, V.1
Lo Celso, C.2
Giangreco, A.3
Ofstad, T.4
Prowse, D.M.5
-
33
-
-
38749149224
-
Bone regeneration is regulated by Wnt signaling
-
Kim JB, Leucht P, Lam K, Luppen C, Ten Berge D, et al. (2007) Bone regeneration is regulated by Wnt signaling. J Bone Miner Res 22: 1913-1923.
-
(2007)
J Bone Miner Res
, vol.22
, pp. 1913-1923
-
-
Kim, J.B.1
Leucht, P.2
Lam, K.3
Luppen, C.4
Ten Berge, D.5
|