Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos

Science

Volumn 300, Issue 5627, 2003, Pages 1957-1961

  Colombo, Kelly ^a   Grill, Stephan W ^b   Kimple, Randall J ^c   Willard, Francis S ^c   Siderovski, David P ^c   Gönczy, Pierre ^a  

^a SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

^b MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEDICAL APPLICATIONS; PHOSPHORUS COMPOUNDS; PROTEINS;

CELL DIVERSITY;

CELLS;

ALPHA TUBULIN; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE DIPHOSPHATE; PROTEIN GOA 1; PROTEIN GPA 16; PROTEIN GPR 1; PROTEIN GPR 2; REGULATOR PROTEIN; RNA; UNCLASSIFIED DRUG;

BIOLOGY; EMBRYO;

ARTICLE; BLASTOMERE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; EMBRYO; EMBRYO AXIS; EMBRYO POLARITY; FORCE; METAPHASE; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; SURFACE PLASMON RESONANCE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL DIVISION; CELL POLARITY; CUES; GTP-BINDING PROTEINS; MITOTIC SPINDLE APPARATUS; PHENOTYPE; PROTEIN SUBUNITS; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TWO-HYBRID SYSTEM TECHNIQUES;

CAENORHABDITIS ELEGANS; INVERTEBRATA; RICKETTSIA SP. PAR;

EID: 0038046388     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1084146     Document Type: Article

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30. We thank A. Ashford, J. Corbitt, T. K. Harden, M. Glozter, A. Hyman, M. Koelle, Y. Kohara, G. Seydoux, and V. Simanis for reagents; A. Debant and S. Schmidt for advice; K. Baumer for technical support; M. Brauchle for movie S1; and K. Afshar, M. Delattre, and M. Labouesse for critical reading of the manuscript. Supported by Swiss National Science Foundation grant 31-62102.00 (P.G.) and NIH grant GM62338 (D.P.S.).