메뉴 건너뛰기




Volumn 86, Issue 2, 1996, Pages 221-232

The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN;

EID: 0030602796     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80094-X     Document Type: Article
Times cited : (493)

References (86)
  • 1
    • 0028329349 scopus 로고
    • Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein
    • Basler, K., and Struhl, G. (1994). Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature 368, 208-214.
    • (1994) Nature , vol.368 , pp. 208-214
    • Basler, K.1    Struhl, G.2
  • 2
    • 0025998891 scopus 로고
    • Roles of wingless in patterning the larval epidermis of Drosophila
    • Bejsovec, A., and Martinez Arias, A. (1991). Roles of wingless in patterning the larval epidermis of Drosophila. Development 113, 471-485.
    • (1991) Development , vol.113 , pp. 471-485
    • Bejsovec, A.1    Martinez Arias, A.2
  • 3
    • 0027386246 scopus 로고
    • Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos
    • Bejsovec, A., and Wieschaus, E. (1993). Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. Development 119, 501-517.
    • (1993) Development , vol.119 , pp. 501-517
    • Bejsovec, A.1    Wieschaus, E.2
  • 5
    • 0027983638 scopus 로고
    • Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings
    • Capdevila, J., and Guerrero, I. (1994). Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings. EMBO J. 13, 4459-4468.
    • (1994) EMBO J. , vol.13 , pp. 4459-4468
    • Capdevila, J.1    Guerrero, I.2
  • 6
    • 0028032065 scopus 로고
    • The Drosophila segment polarity gene patched interacts with decapentaplegic in wing development
    • Capdevila, J., Estrada, M.P., Sánchez-Herrero, E., and Guerrero, I. (1994). The Drosophila segment polarity gene patched interacts with decapentaplegic in wing development. EMBO J. 13, 71-82.
    • (1994) EMBO J. , vol.13 , pp. 71-82
    • Capdevila, J.1    Estrada, M.P.2    Sánchez-Herrero, E.3    Guerrero, I.4
  • 7
    • 0023664018 scopus 로고
    • Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates
    • Cavener, D.R. (1987). Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates. Nucl. Acids Res. 15, 1353-1361.
    • (1987) Nucl. Acids Res. , vol.15 , pp. 1353-1361
    • Cavener, D.R.1
  • 9
    • 0023919954 scopus 로고
    • Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis
    • DiNardo, S., Sher, E., Heemskerk-Jongens, J., Kassis, J.A., and O'Farrell, P.H. (1988). Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis. Nature 332, 604-609.
    • (1988) Nature , vol.332 , pp. 604-609
    • DiNardo, S.1    Sher, E.2    Heemskerk-Jongens, J.3    Kassis, J.A.4    O'Farrell, P.H.5
  • 10
    • 0029896212 scopus 로고    scopus 로고
    • Sending and receiving the Hedgehog signal: Control by the Drosophila Gli protein Cubitus interruptus
    • Domínguez, M., Brunner, M., Hafen, E., and Basler, K. (1996). Sending and receiving the Hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus. Science 272, 1621-1625.
    • (1996) Science , vol.272 , pp. 1621-1625
    • Domínguez, M.1    Brunner, M.2    Hafen, E.3    Basler, K.4
  • 11
    • 0025283924 scopus 로고
    • Repression of ci-D in posterior compartments of Drosophila by engrailed
    • Eaton, S., and Kornberg, T.B. (1990). Repression of ci-D in posterior compartments of Drosophila by engrailed. Genes Dev. 4, 1068-1077.
    • (1990) Genes Dev. , vol.4 , pp. 1068-1077
    • Eaton, S.1    Kornberg, T.B.2
  • 12
    • 0027817446 scopus 로고
    • Genetic analysis of hedgehog signaling in the Drosophila embryo
    • Forbes, A.J., Nakano, Y., Taylor, A.M., and Ingham, P.W. (1993). Genetic analysis of hedgehog signaling in the Drosophila embryo. Development (1993 Supplement): 115-124.
    • (1993) Development , Issue.1993 SUPPL. , pp. 115-124
    • Forbes, A.J.1    Nakano, Y.2    Taylor, A.M.3    Ingham, P.W.4
  • 13
    • 0000025319 scopus 로고
    • Cloning of extra sex combs gene of Drosophila and its identification by P-element-mediated gene transfer
    • Frei, E., Baumgartner,S., Edström, J.-E., and Noll, M. (1985). Cloning of extra sex combs gene of Drosophila and its identification by P-element-mediated gene transfer. EMBO J. 4, 979-987.
    • (1985) EMBO J. , vol.4 , pp. 979-987
    • Frei, E.1    Edström, J.-E.2    Noll, M.3
  • 14
    • 0025367812 scopus 로고
    • Sequence differences between glycosylated and nonglycosylated Asn-X-Thr/Ser acceptor sites: Implications for protein engineering
    • Gavel, Y., and von Heijne, G. (1990). Sequence differences between glycosylated and nonglycosylated Asn-X-Thr/Ser acceptor sites: implications for protein engineering. Protein Eng. 3, 433-442.
    • (1990) Protein Eng. , vol.3 , pp. 433-442
    • Gavel, Y.1    Von Heijne, G.2
  • 15
    • 0022978498 scopus 로고
    • Synthetic peptides corresponding to the site phosphorylated in 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as substrates of cyclic nucleotide-dependent protein kinases
    • Glass, D.B., El-Maghrabi, M.R., and Pilkis, S.J. (1986). Synthetic peptides corresponding to the site phosphorylated in 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as substrates of cyclic nucleotide-dependent protein kinases. J. Biol. Chem. 261, 2987-2993.
    • (1986) J. Biol. Chem. , vol.261 , pp. 2987-2993
    • Glass, D.B.1    El-Maghrabi, M.R.2    Pilkis, S.J.3
  • 16
    • 0025744384 scopus 로고
    • Secretion and movement of wingless protein in the epidermis of the Drosophila embryo
    • Gonzalez, F., Swales, L., Bejsovec, A., Skaer, H., and Martinez Arias, A. (1991). Secretion and movement of wingless protein in the epidermis of the Drosophila embryo. Mech. Dev. 35, 43-54.
    • (1991) Mech. Dev. , vol.35 , pp. 43-54
    • Gonzalez, F.1    Swales, L.2    Bejsovec, A.3    Skaer, H.4    Martinez Arias, A.5
  • 17
    • 0003448569 scopus 로고
    • (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press)
    • Harlow, E., and Lane, D. (1988). Antibodies: A Laboratory Manual. (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press).
    • (1988) Antibodies: A Laboratory Manual
    • Harlow, E.1    Lane, D.2
  • 18
    • 0028008784 scopus 로고
    • Drosophila hedgehog acts as a morphogen in cellular patterning
    • Heemskerk, J., and DiNardo, S. (1994). Drosophila hedgehog acts as a morphogen in cellular patterning. Cell 76, 449-460.
    • (1994) Cell , vol.76 , pp. 449-460
    • Heemskerk, J.1    DiNardo, S.2
  • 19
    • 0025823967 scopus 로고
    • Multiple modes of engrailed regulation in the progression towards cell fate determination
    • Heemskerk, J., DiNardo, S., Kostriken, R., and O'Farrell, P.H. (1991). Multiple modes of engrailed regulation in the progression towards cell fate determination. Nature 352, 404-410.
    • (1991) Nature , vol.352 , pp. 404-410
    • Heemskerk, J.1    DiNardo, S.2    Kostriken, R.3    O'Farrell, P.H.4
  • 20
    • 0026012268 scopus 로고
    • Interactions between segment polarity genes and the generation of the segmental pattern in Drosophila
    • Hidalgo, A. (1991). Interactions between segment polarity genes and the generation of the segmental pattern in Drosophila. Mech. Dev. 35, 77-87.
    • (1991) Mech. Dev. , vol.35 , pp. 77-87
    • Hidalgo, A.1
  • 21
    • 0025072659 scopus 로고
    • Cell patterning in the Drosophila segment: Spatial regulation of the segment polarity gene patched
    • Hidalgo, A., and Ingham, P. (1990). Cell patterning in the Drosophila segment: spatial regulation of the segment polarity gene patched. Development 110, 291-301.
    • (1990) Development , vol.110 , pp. 291-301
    • Hidalgo, A.1    Ingham, P.2
  • 22
    • 0000207681 scopus 로고
    • A database of membrane-spanning protein segments
    • Hofmann, K., and Stoffel, W. (1993). A database of membrane-spanning protein segments. Biol. Chem. Hoppe Seyler 374, 166.
    • (1993) Biol. Chem. Hoppe Seyler , vol.374 , pp. 166
    • Hofmann, K.1    Stoffel, W.2
  • 23
    • 0028077841 scopus 로고
    • Distinct pathways for autocrine and paracrine Wingless signaling in Drosophila embryos
    • Hooper, J.E. (1994). Distinct pathways for autocrine and paracrine Wingless signaling in Drosophila embryos. Nature 372, 461-464.
    • (1994) Nature , vol.372 , pp. 461-464
    • Hooper, J.E.1
  • 24
    • 0024468746 scopus 로고
    • The Drosophila patched gene encodes a putative membrane protein required for segmental patterning
    • Hooper, J.E., and Scott, M.P. (1989). The Drosophila patched gene encodes a putative membrane protein required for segmental patterning. Cell 59, 751-765.
    • (1989) Cell , vol.59 , pp. 751-765
    • Hooper, J.E.1    Scott, M.P.2
  • 25
    • 0027761917 scopus 로고
    • Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo
    • Ingham, P.W. (1993). Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo. Nature 366, 560-562.
    • (1993) Nature , vol.366 , pp. 560-562
    • Ingham, P.W.1
  • 26
    • 0029121566 scopus 로고
    • Signalling by hedgehog family proteins in Drosophila and vertebrate development
    • Ingham, P.W. (1995). Signalling by hedgehog family proteins in Drosophila and vertebrate development. Curr. Opin. Genet. Dev. 5, 492-498.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 492-498
    • Ingham, P.W.1
  • 27
    • 0027408032 scopus 로고
    • Regulation of wingless transcription in the Drosophila embryo
    • Ingham, P.W., and Hidalgo, A. (1993). Regulation of wingless transcription in the Drosophila embryo. Development 117, 283-291.
    • (1993) Development , vol.117 , pp. 283-291
    • Ingham, P.W.1    Hidalgo, A.2
  • 28
    • 0025815911 scopus 로고
    • Role of the Drosophila patched gene in positional signaling
    • Ingham, P.W., Taylor, A.M., and Nakano, Y. (1991). Role of the Drosophila patched gene in positional signaling. Nature 353, 184-187.
    • (1991) Nature , vol.353 , pp. 184-187
    • Ingham, P.W.1    Taylor, A.M.2    Nakano, Y.3
  • 29
    • 0028918468 scopus 로고
    • Protein kinase A and Hedgehog signaling in Drosophila limb development
    • Jiang, J., and Struhl, G. (1995). Protein kinase A and Hedgehog signaling in Drosophila limb development. Cell 80, 563-572.
    • (1995) Cell , vol.80 , pp. 563-572
    • Jiang, J.1    Struhl, G.2
  • 30
    • 0025979191 scopus 로고
    • Autoregulation of a segmentation gene in Drosophila: Combinatorial interaction of the evenskipped homeobox protein with a distal enhancer element
    • Jiang, J., Hoey, T., and Levine, M. (1991). Autoregulation of a segmentation gene in Drosophila: combinatorial interaction of the evenskipped homeobox protein with a distal enhancer element. Genes Dev. 5, 265-277.
    • (1991) Genes Dev. , vol.5 , pp. 265-277
    • Jiang, J.1    Hoey, T.2    Levine, M.3
  • 31
    • 0029417009 scopus 로고
    • Patched overexpression alters wing disc size and pattern: Transcriptional and posttranscriptional effects on hedgehog targets
    • Johnson, R.L., Grenier, J.K., and Scott, M.P. (1995). patched overexpression alters wing disc size and pattern: transcriptional and posttranscriptional effects on hedgehog targets. Development 121, 4161-4170.
    • (1995) Development , vol.121 , pp. 4161-4170
    • Johnson, R.L.1    Grenier, J.K.2    Scott, M.P.3
  • 32
    • 34250134008 scopus 로고
    • Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster: Zygotic loci on the third chromosome
    • Jürgens, G., Wieschaus, E., Nüsslein-Volhard, C., and Kluding, H. (1984). Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster: zygotic loci on the third chromosome. Roux's Arch. Dev. Biol. 193, 283-295.
    • (1984) Roux's Arch. Dev. Biol. , vol.193 , pp. 283-295
    • Jürgens, G.1    Wieschaus, E.2    Nüsslein-Volhard, C.3    Kluding, H.4
  • 33
    • 0025047508 scopus 로고
    • The Drosophila segmentation gene runf encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system
    • Kania, M.A., Bonner, A.S., Duffy, J.B., and Gergen, J.P. (1990). The Drosophila segmentation gene runf encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system. Genes Dev. 4, 1701-1713.
    • (1990) Genes Dev. , vol.4 , pp. 1701-1713
    • Kania, M.A.1    Bonner, A.S.2    Duffy, J.B.3    Gergen, J.P.4
  • 34
    • 0022444539 scopus 로고
    • Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis
    • Kilchherr, F., Baumgartner, S., Bopp, D., Frei, E., and Noll, M. (1986). Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis. Nature 321, 493-499.
    • (1986) Nature , vol.321 , pp. 493-499
    • Kilchherr, F.1    Baumgartner, S.2    Bopp, D.3    Frei, E.4    Noll, M.5
  • 35
    • 0026551650 scopus 로고
    • Adrenergic receptors as models for G protein-coupled receptors
    • Kobilka, B. (1992). Adrenergic receptors as models for G protein-coupled receptors. Annu. Rev. Neurosci. 15, 87-114.
    • (1992) Annu. Rev. Neurosci. , vol.15 , pp. 87-114
    • Kobilka, B.1
  • 36
    • 0023665902 scopus 로고
    • An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs
    • Kozak, M. (1987). An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucl. Acids Res. 15, 8125-8148.
    • (1987) Nucl. Acids Res. , vol.15 , pp. 8125-8148
    • Kozak, M.1
  • 37
    • 0023251895 scopus 로고
    • Borders of parasegments in Drosophila embryos are delimited by the fushi tarazu and even-skipped genes
    • Lawrence, P.A., Johnston, P., Macdonald, P., and Struhl, G. (1987). Borders of parasegments in Drosophila embryos are delimited by the fushi tarazu and even-skipped genes. Nature 328, 440-442.
    • (1987) Nature , vol.328 , pp. 440-442
    • Lawrence, P.A.1    Johnston, P.2    Macdonald, P.3    Struhl, G.4
  • 38
    • 0026783674 scopus 로고
    • Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog
    • Lee, J.J., von Kessler, D.P., Parks, S., and Beachy, P.A. (1992). Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog. Cell 71, 33-50.
    • (1992) Cell , vol.71 , pp. 33-50
    • Lee, J.J.1    Von Kessler, D.P.2    Parks, S.3    Beachy, P.A.4
  • 39
    • 0028952718 scopus 로고
    • Signal transduction by cAMP-dependent protein kinase A in Drosophila limb patterning
    • Lepage, T., Cohen, S.M., Diaz-Benjumea, F.J., Parkhurst, S.M. (1995). Signal transduction by cAMP-dependent protein kinase A in Drosophila limb patterning. Nature 373, 711-715.
    • (1995) Nature , vol.373 , pp. 711-715
    • Lepage, T.1    Cohen, S.M.2    Diaz-Benjumea, F.J.3    Parkhurst, S.M.4
  • 40
    • 0027377564 scopus 로고
    • Role of the gooseberry gene in Drosophila embryos: Maintenance of wingless expression by a wingless-gooseberry autoregulatory loop
    • Li, X., and Noll, M. (1993). Role of the gooseberry gene in Drosophila embryos: maintenance of wingless expression by a wingless-gooseberry autoregulatory loop. EMBO J. 12, 4499-4509.
    • (1993) EMBO J. , vol.12 , pp. 4499-4509
    • Li, X.1    Noll, M.2
  • 41
    • 0028897883 scopus 로고
    • Function of protein kinase A in Hedgehog signal transduction and Drosophila imaginal disc development
    • Li, W., Ohlmeyer, J.T., Lane, M.E., and Kalderon, D. (1995). Function of protein kinase A in Hedgehog signal transduction and Drosophila imaginal disc development. Cell 80, 553-562.
    • (1995) Cell , vol.80 , pp. 553-562
    • Li, W.1    Ohlmeyer, J.T.2    Lane, M.E.3    Kalderon, D.4
  • 42
    • 0025872507 scopus 로고
    • Interactions between fused, a segment polarity gene in Drosophila, and other segmentation genes
    • Limbourg-Bouchon, B., Busson, D., and Lamour-Isnard, C. (1991). Interactions between fused, a segment polarity gene in Drosophila, and other segmentation genes. Development 112, 417-429.
    • (1991) Development , vol.112 , pp. 417-429
    • Limbourg-Bouchon, B.1    Busson, D.2    Lamour-Isnard, C.3
  • 44
    • 0027741258 scopus 로고
    • The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye
    • Ma, C., Zhou, Y., Beachy, P.A., and Moses, K. (1993). The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye. Cell 75, 927-938.
    • (1993) Cell , vol.75 , pp. 927-938
    • Ma, C.1    Zhou, Y.2    Beachy, P.A.3    Moses, K.4
  • 46
    • 0021930186 scopus 로고
    • Parasegments and compartments in the Drosophila embryo
    • Martinez-Arias, A., and Lawrence, P.A. (1985). Parasegments and compartments in the Drosophila embryo. Nature 313, 639-642.
    • (1985) Nature , vol.313 , pp. 639-642
    • Martinez-Arias, A.1    Lawrence, P.A.2
  • 47
    • 0023895153 scopus 로고
    • Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo
    • Martinez Arias, A., Baker, N.E., and Ingham, P.W. (1988). Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo. Development 103, 157-170.
    • (1988) Development , vol.103 , pp. 157-170
    • Martinez Arias, A.1    Baker, N.E.2    Ingham, P.W.3
  • 48
    • 0029126148 scopus 로고
    • The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways
    • Motzny, C.K., and Holmgren, R. (1995). The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways. Mech. Dev. 52, 137-150.
    • (1995) Mech. Dev. , vol.52 , pp. 137-150
    • Motzny, C.K.1    Holmgren, R.2
  • 49
    • 0024440611 scopus 로고
    • A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched
    • Nakano, Y., Guerrero, I., Hidalgo, A., Taylor, A., Whittle, J.R.S., and Ingham, P.W. (1989). A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched. Nature 341, 508-513.
    • (1989) Nature , vol.341 , pp. 508-513
    • Nakano, Y.1    Guerrero, I.2    Hidalgo, A.3    Taylor, A.4    Whittle, J.R.S.5    Ingham, P.W.6
  • 50
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in Drosophila
    • Nüsslein-Volhard, C., and Wieschaus, E. (1980). Mutations affecting segment number and polarity in Drosophila. Nature 287, 795-801.
    • (1980) Nature , vol.287 , pp. 795-801
    • Nüsslein-Volhard, C.1    Wieschaus, E.2
  • 51
    • 0008125299 scopus 로고
    • Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster: Zygotic loci on the second chromosome
    • Nüsslein-Volhard, C., Wieschaus, E., and Kluding, H. (1984). Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster: zygotic loci on the second chromosome. Roux's Arch. Dev. Biol. 193, 267-282.
    • (1984) Roux's Arch. Dev. Biol. , vol.193 , pp. 267-282
    • Nüsslein-Volhard, C.1    Wieschaus, E.2    Kluding, H.3
  • 52
    • 0025331133 scopus 로고
    • Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila
    • Orenic, T.V., Slusarski, D.C., Kroll, K.L., and Holmgren, R. (1990). Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila. Genes Dev. 4, 1053-1067.
    • (1990) Genes Dev. , vol.4 , pp. 1053-1067
    • Orenic, T.V.1    Slusarski, D.C.2    Kroll, K.L.3    Holmgren, R.4
  • 53
    • 0028911915 scopus 로고
    • cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in Drosophila imaginal discs
    • Pan, D., and Rubin, G.M. (1995). cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in Drosophila imaginal discs. Cell 80, 543-552.
    • (1995) Cell , vol.80 , pp. 543-552
    • Pan, D.1    Rubin, G.M.2
  • 54
    • 0028107138 scopus 로고
    • The frizzled gene of Drosophila encodes a membrane protein with an odd number of transmembrane domains
    • Park, W.-J., Liu, J., and Adler, P.N. (1994). The frizzled gene of Drosophila encodes a membrane protein with an odd number of transmembrane domains. Mech. Dev. 45, 127-137.
    • (1994) Mech. Dev. , vol.45 , pp. 127-137
    • Park, W.-J.1    Liu, J.2    Adler, P.N.3
  • 55
    • 0026710309 scopus 로고
    • Knowing your neighbors: Cell interactions determine intrasegmental patterning in Drosophila
    • Peifer, M., and Bejsovec, A. (1992). Knowing your neighbors: cell interactions determine intrasegmental patterning in Drosophila. Trends Genet. 8, 243-249.
    • (1992) Trends Genet. , vol.8 , pp. 243-249
    • Peifer, M.1    Bejsovec, A.2
  • 56
    • 0025729647 scopus 로고
    • The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation
    • Peifer, M., Rauskolb, C., Williams, M., Riggleman, B., and Wieschaus, E. (1991). The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation. Development 111, 1029-1043.
    • (1991) Development , vol.111 , pp. 1029-1043
    • Peifer, M.1    Rauskolb, C.2    Williams, M.3    Riggleman, B.4    Wieschaus, E.5
  • 57
    • 0028209401 scopus 로고
    • The genetic basis of patterned baldness in Drosophila
    • Perrimon, N. (1994). The genetic basis of patterned baldness in Drosophila. Cell 76, 781-784.
    • (1994) Cell , vol.76 , pp. 781-784
    • Perrimon, N.1
  • 58
    • 0028909706 scopus 로고
    • Hedgehog and beyond
    • Perrimon, N. (1995). Hedgehog and beyond. Cell 80, 517-520.
    • (1995) Cell , vol.80 , pp. 517-520
    • Perrimon, N.1
  • 59
    • 0025030276 scopus 로고
    • The Drosophila segment polarity gene patched is involved in a position-signaling mechanism in imaginal discs
    • Phillips, R.G., Roberts, I.J.H., Ingham, P.W., and Whittle, J.R.S. (1990). The Drosophila segment polarity gene patched is involved in a position-signaling mechanism in imaginal discs. Development 110, 105-114.
    • (1990) Development , vol.110 , pp. 105-114
    • Phillips, R.G.1    Roberts, I.J.H.2    Ingham, P.W.3    Whittle, J.R.S.4
  • 60
    • 0000870124 scopus 로고
    • Vectors for P-mediated transformation in Drosophila
    • R.L. Rodriguez, and D.T. Denhardt, eds. (Boston: Butterworth)
    • Pirrotta, V. (1988). Vectors for P-mediated transformation in Drosophila. In Vectors: A Survey of Molecular Cloning Vectors and Their Uses, R.L. Rodriguez, and D.T. Denhardt, eds. (Boston: Butterworth).
    • (1988) Vectors: A Survey of Molecular Cloning Vectors and Their Uses
    • Pirrotta, V.1
  • 61
    • 0028948811 scopus 로고
    • The product of hedgehog autoproteolytic cleavage active in local and long-range signaling
    • Porter, J.A., von Kessler, D.P., Ekker, S.C., Young, K.E., Lee, J.J., Moses, K., and Beachy, P.A. (1995). The product of hedgehog autoproteolytic cleavage active in local and long-range signaling. Nature 374, 363-366.
    • (1995) Nature , vol.374 , pp. 363-366
    • Porter, J.A.1    Von Kessler, D.P.2    Ekker, S.C.3    Young, K.E.4    Lee, J.J.5    Moses, K.6    Beachy, P.A.7
  • 62
    • 0027383291 scopus 로고
    • Segmental polarity in Drosophila melanogaster: Genetic dissection of fused in a Suppressor of fused background reveals interaction with costal-2
    • Préat, T., Thérond, P., Limbourg-Bouchon, B., Pham, A., Tricoire, H., Busson, D., and Lamourd-Isnard, C. (1993). Segmental polarity in Drosophila melanogaster: genetic dissection of fused in a Suppressor of fused background reveals interaction with costal-2. Genetics 135, 1047-1062.
    • (1993) Genetics , vol.135 , pp. 1047-1062
    • Préat, T.1    Thérond, P.2    Limbourg-Bouchon, B.3    Pham, A.4    Tricoire, H.5    Busson, D.6    Lamourd-Isnard, C.7
  • 63
    • 0019945644 scopus 로고
    • Genetic transformation of Drosophila with transposable element vectors
    • Rubin, G.M., and Spradling, A.C. (1982). Genetic transformation of Drosophila with transposable element vectors. Science 218, 348-353.
    • (1982) Science , vol.218 , pp. 348-353
    • Rubin, G.M.1    Spradling, A.C.2
  • 64
    • 0026537051 scopus 로고
    • The origin of pattern and polarity in the Drosophila embryo
    • St Johnston, D., and Nüsslein-Volhard, C. (1992). The origin of pattern and polarity in the Drosophila embryo. Cell 68, 201-219.
    • (1992) Cell , vol.68 , pp. 201-219
    • St. Johnston, D.1    Nüsslein-Volhard, C.2
  • 65
    • 0025767994 scopus 로고
    • Unrestricted expression of the Drosophila gene patched allows a normal segment polarity
    • Sampedro, J., and Guerrero, I. (1991). Unrestricted expression of the Drosophila gene patched allows a normal segment polarity. Nature 353, 187-190.
    • (1991) Nature , vol.353 , pp. 187-190
    • Sampedro, J.1    Guerrero, I.2
  • 66
    • 0027417887 scopus 로고
    • Molecular genetics of aristaless, aprd-type homeobox gene involved in the morphogenesis of proximal and distal pattern elements in a subset of appendages in Drosophila
    • Schneitz, K., Spielmann, P., and Noll, M. (1993). Molecular genetics of aristaless, aprd-type homeobox gene involved in the morphogenesis of proximal and distal pattern elements in a subset of appendages in Drosophila. Genes Dev. 7, 114-129.
    • (1993) Genes Dev. , vol.7 , pp. 114-129
    • Schneitz, K.1    Spielmann, P.2    Noll, M.3
  • 67
    • 0028168791 scopus 로고
    • Patched overexpression causes loss of wingless expression in Drosophila embryos
    • Schuske, K., Hooper, J.E., and Scott, M. (1994). patched overexpression causes loss of wingless expression in Drosophila embryos. Dev. Biol. 164, 300-311.
    • (1994) Dev. Biol. , vol.164 , pp. 300-311
    • Schuske, K.1    Hooper, J.E.2    Scott, M.3
  • 68
    • 0027070855 scopus 로고
    • Wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate
    • Siegfried, E., Chou, T.-B., and Perrimon, N. (1992). wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate. Cell 71, 1167-1179.
    • (1992) Cell , vol.71 , pp. 1167-1179
    • Siegfried, E.1    Chou, T.-B.2    Perrimon, N.3
  • 69
    • 0027948042 scopus 로고
    • Components of wingless signaling in Drosophila
    • Siegfried, E., Wilder, E.L., and Perrimon, N. (1994). Components of wingless signaling in Drosophila. Nature 367, 76-80.
    • (1994) Nature , vol.367 , pp. 76-80
    • Siegfried, E.1    Wilder, E.L.2    Perrimon, N.3
  • 70
    • 0026199993 scopus 로고
    • The initiation of pair-rule stripes in the Drosophila blastoderm
    • Small, S., and Levine, M. (1991). The initiation of pair-rule stripes in the Drosophila blastoderm. Curr. Opin. Genet. Dev. 1, 255-260.
    • (1991) Curr. Opin. Genet. Dev. , vol.1 , pp. 255-260
    • Small, S.1    Levine, M.2
  • 72
    • 0028906799 scopus 로고
    • Regulation of furrow progression in the Drosophila eye by cAMP-dependent protein kinase A
    • Strutt, D.I., Wiersdorff, V., and Mlodzik, M. (1995). Regulation of furrow progression in the Drosophila eye by cAMP-dependent protein kinase A. Nature 373, 705-709.
    • (1995) Nature , vol.373 , pp. 705-709
    • Strutt, D.I.1    Wiersdorff, V.2    Mlodzik, M.3
  • 73
    • 0028178786 scopus 로고
    • Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs
    • Tabata, T., and Kornberg, T.B. (1994). Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell 76, 89-102.
    • (1994) Cell , vol.76 , pp. 89-102
    • Tabata, T.1    Kornberg, T.B.2
  • 74
    • 0024319520 scopus 로고
    • A nonradioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback
    • Tautz, D., and Pfeifle, C. (1989). A nonradioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.
    • (1989) Chromosoma , vol.98 , pp. 81-85
    • Tautz, D.1    Pfeifle, C.2
  • 75
    • 0027200833 scopus 로고
    • Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo
    • Taylor, A.M., Nakano, Y., Mohler, J., and Ingham, P.W. (1993). Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo. Mech. Dev. 42, 89-96.
    • (1993) Mech. Dev. , vol.42 , pp. 89-96
    • Taylor, A.M.1    Nakano, Y.2    Mohler, J.3    Ingham, P.W.4
  • 76
    • 0029961659 scopus 로고    scopus 로고
    • Phosphorylation of the fused protein kinase in response to signaling from hedgehog
    • Thérond, P.P., Knight, J.D., Kornberg, T.B., and Bishop, J.M. (1996). Phosphorylation of the fused protein kinase in response to signaling from hedgehog. Proc. Natl. Acad. Sci. USA 93, 4224-4228.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4224-4228
    • Thérond, P.P.1    Knight, J.D.2    Kornberg, T.B.3    Bishop, J.M.4
  • 77
    • 0024453493 scopus 로고
    • Distribution of the wingless gene product in Drosophila embryos: A protein involved in cell-cell communication
    • van den Heuvel, M., Nusse, R., Johnston, P., and Lawrence, P.A. (1989). Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication. Cell 59, 739-749.
    • (1989) Cell , vol.59 , pp. 739-749
    • Van Den Heuvel, M.1    Nusse, R.2    Johnston, P.3    Lawrence, P.A.4
  • 78
    • 0027849704 scopus 로고
    • Cell patterning in the Drosophila segment: Engrailed and wingless antigen distributions in segment polarity mutant embryos
    • van den Heuvel, M., Klingensmith, J., Perrimon, N., and Nusse, R. (1993). Cell patterning in the Drosophila segment: engrailed and wingless antigen distributions in segment polarity mutant embryos. Development (1993 Supplement): 105-114.
    • (1993) Development , Issue.1993 SUPPL. , pp. 105-114
    • Van Den Heuvel, M.1    Klingensmith, J.2    Perrimon, N.3    Nusse, R.4
  • 79
    • 0028228618 scopus 로고
    • Drosophila wingless sustains engrailed expression only in adjoining cells: Evidence from mosaic embryos
    • Vincent, J.-P., and Lawrence, P.A. (1994). Drosophila wingless sustains engrailed expression only in adjoining cells: evidence from mosaic embryos. Cell 77, 909-915.
    • (1994) Cell , vol.77 , pp. 909-915
    • Vincent, J.-P.1    Lawrence, P.A.2
  • 80
    • 0024972122 scopus 로고
    • A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains
    • Vinson, C.R., Conover, S., and Adler, P.N. (1989). A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains. Nature 338, 263-264.
    • (1989) Nature , vol.338 , pp. 263-264
    • Vinson, C.R.1    Conover, S.2    Adler, P.N.3
  • 81
    • 0023046815 scopus 로고
    • A new method for predicting signal sequence cleavage sites
    • von Heijne, G. (1986). A new method for predicting signal sequence cleavage sites. Nucl. Acids Res. 14, 4683-4690.
    • (1986) Nucl. Acids Res. , vol.14 , pp. 4683-4690
    • Von Heijne, G.1
  • 83
    • 0028898615 scopus 로고
    • Dual functions of wingless in the Drosophila leg imaginal disc
    • Wilder, E., and Perrimon, N. (1995). Dual functions of wingless in the Drosophila leg imaginal disc. Development 121, 477-488.
    • (1995) Development , vol.121 , pp. 477-488
    • Wilder, E.1    Perrimon, N.2
  • 84
    • 0029114331 scopus 로고
    • Evidence for engrailed-independent wingless autoregulation in Drosophila
    • Yoffe, K.B., Manoukian, A.S., Wilder, E.L., Brand, A.H., and Perrimon, N. (1995). Evidence for engrailed-independent wingless autoregulation in Drosophila. Dev. Biol. 170, 636-650.
    • (1995) Dev. Biol. , vol.170 , pp. 636-650
    • Yoffe, K.B.1    Manoukian, A.S.2    Wilder, E.L.3    Brand, A.H.4    Perrimon, N.5
  • 85
    • 0028216368 scopus 로고
    • Ectopic expression of either the Drosophila gooseberry-distal or gooseberry-proximal gene causes alterations of cell fate in the epidermis and central nervous system
    • Zhang, Y., Ungar, A., Fersquez, C., and Holmgren, R. (1994). Ectopic expression of either the Drosophila gooseberry-distal or gooseberry-proximal gene causes alterations of cell fate in the epidermis and central nervous system. Development 120, 1151-1161.
    • (1994) Development , vol.120 , pp. 1151-1161
    • Zhang, Y.1    Ungar, A.2    Fersquez, C.3    Holmgren, R.4
  • 86
    • 0029046712 scopus 로고
    • A human homologue of the Drosophila polarity gene frizzled has been identified and mapped to 17q21.1
    • Zhao, Z., Lee, C.C., Baldini, A., and Caskey, C.T. (1995). A human homologue of the Drosophila polarity gene frizzled has been identified and mapped to 17q21.1. Genomics 27, 370-373.
    • (1995) Genomics , vol.27 , pp. 370-373
    • Zhao, Z.1    Lee, C.C.2    Baldini, A.3    Caskey, C.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.