-
1
-
-
76149111947
-
Inflammatory lipid mediators in adipocyte function and obesity
-
Iyer, A.; Fairlie, D.P.; Prins, J.B.; Hammock, B.D. and Brown, L. (2010) Inflammatory lipid mediators in adipocyte function and obesity. Nat. Rev. Endocrinol., 6, 71-82.
-
(2010)
Nat. Rev. Endocrinol
, vol.6
, pp. 71-82
-
-
Iyer, A.1
Fairlie, D.P.2
Prins, J.B.3
Hammock, B.D.4
Brown, L.5
-
2
-
-
57349096045
-
The metabolic syndrome
-
Cornier, M.A.; Dabelea, D.; Hernandez, T.L.; Lindstrom, R.C.; Steig, A.J.; Stob, N.R.; Van Pelt, R.E.; Wang, H. and Eckel, R.H. (2008) The metabolic syndrome. Endocr. Rev., 29, 777-822.
-
(2008)
Endocr. Rev
, vol.29
, pp. 777-822
-
-
Cornier, M.A.1
Dabelea, D.2
Hernandez, T.L.3
Lindstrom, R.C.4
Steig, A.J.5
Stob, N.R.6
van Pelt, R.E.7
Wang, H.8
Eckel, R.H.9
-
3
-
-
70450233538
-
Activation of the AMP activated protein kinase by short-chain fatty acids is the main mechanism underlying the beneficial effect of a high fiber diet on the metabolic syndrome
-
Hu, G.X.; Chen, G.R.; Xu, H.; Ge, R.S. and Lin, J. (2010) Activation of the AMP activated protein kinase by short-chain fatty acids is the main mechanism underlying the beneficial effect of a high fiber diet on the metabolic syndrome. Med. Hypotheses., 74, 123-126.
-
(2010)
Med. Hypotheses
, vol.74
, pp. 123-126
-
-
Hu, G.X.1
Chen, G.R.2
Xu, H.3
Ge, R.S.4
Lin, J.5
-
4
-
-
0034692315
-
Diabetes in international perspective
-
Jervell, J. (2000) Diabetes in international perspective. Tidsskr Nor Laegeforen, 120, 2686-2689.
-
(2000)
Tidsskr Nor Laegeforen
, vol.120
, pp. 2686-2689
-
-
Jervell, J.1
-
5
-
-
85038497776
-
-
The IDF consensus worldwide definition of the metabolic syndrome 2006, Accessed January 26, 2011
-
The IDF consensus worldwide definition of the metabolic syndrome 2006. http://www.idf.org (Accessed January 26, 2011).
-
-
-
-
6
-
-
77949273315
-
The metabolic syndrome: Useful concept or clinical tool? Report of a WHO Expert Consultation
-
Simmons, R.K.; Alberti, K.G.; Gale, E.A.; Colagiuri, S.; Tuomilehto, J.; Qiao, Q.; Ramachandran, A.; Tajima, N.; Brajkovich Mirchov, I.; Ben-Nakhi, A.; Reaven, G.; Hama Sambo, B.; Mendis, S. and Roglic, G. (2010) The metabolic syndrome: useful concept or clinical tool? Report of a WHO Expert Consultation. Diabetologia, 53, 600-605.
-
(2010)
Diabetologia
, vol.53
, pp. 600-605
-
-
Simmons, R.K.1
Alberti, K.G.2
Gale, E.A.3
Colagiuri, S.4
Tuomilehto, J.5
Qiao, Q.6
Ramachandran, A.7
Tajima, N.8
Brajkovich, M.I.9
Ben-Nakhi, A.10
Reaven, G.11
Hama, S.B.12
Mendis, S.13
Roglic, G.14
-
7
-
-
77956679615
-
Here we go again. . . The metabolic syndrome revisited! Diabetes and Metabolic Syndrome
-
Sadikot, S. and Hermans, M. (2010) Here we go again. . . The metabolic syndrome revisited! Diabetes and Metabolic Syndrome. Clinical Res. Rev., 4, 111-120.
-
(2010)
Clinical Res. Rev
, vol.4
, pp. 111-120
-
-
Sadikot, S.1
Hermans, M.2
-
8
-
-
33845642900
-
The metabolic syndrome: Perhaps an etiologic mystery but far from a myth-where does the International Diabetes Federation stand?
-
Online, Accessed January 26, 2011
-
Zimmet, P.A.G. The metabolic syndrome: perhaps an etiologic mystery but far from a myth-where does the International Diabetes Federation stand? Medscape Diabetes & Endocrinology. [Online], 2005. http://www.medscape.com/viewarticle/514211 (Accessed January 26, 2011).
-
(2005)
Medscape Diabetes & Endocrinology
-
-
Zimmet, P.A.G.1
-
9
-
-
0015864346
-
Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and wth protein fractions of rat liver cytosol
-
Beg, Z.H.; Allmann, D.W. and Gibson, D.M. (1973) Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and wth protein fractions of rat liver cytosol. Biochem. Biophys. Res. Commun., 54, 1362-1369.
-
(1973)
Biochem. Biophys. Res. Commun
, vol.54
, pp. 1362-1369
-
-
Beg, Z.H.1
Allmann, D.W.2
Gibson, D.M.3
-
10
-
-
0015918822
-
Regulation of hepatic acetyl coenzyme A carboxylase by phosphorylation and dephosphorylation
-
Carlson, C.A. and Kim, K.H. (1973) Regulation of hepatic acetyl coenzyme A carboxylase by phosphorylation and dephosphorylation. J. Biol. Chem., 248, 378-380.
-
(1973)
J. Biol. Chem
, vol.248
, pp. 378-380
-
-
Carlson, C.A.1
Kim, K.H.2
-
11
-
-
50049091255
-
AMPK: A key regulator of energy balance in the single cell and the whole organism
-
Hardie, D.G. (2008) AMPK: a key regulator of energy balance in the single cell and the whole organism. Int. J. Obes. (Lond), 32 Suppl 4, S7-12.
-
(2008)
Int. J. Obes. (Lond)
, vol.32
, Issue.SUPPL. 4
-
-
Hardie, D.G.1
-
12
-
-
34147152841
-
Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade
-
Sanders, M.J.; Grondin, P.O.; Hegarty, B.D.; Snowden, M.A. and Carling, D. (2007) Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade. Biochem. J., 403, 139-148.
-
(2007)
Biochem. J
, vol.403
, pp. 139-148
-
-
Sanders, M.J.1
Grondin, P.O.2
Hegarty, B.D.3
Snowden, M.A.4
Carling, D.5
-
13
-
-
63849261100
-
Structure and function of AMP-activated protein kinase
-
Oakhill, J.S.; Scott, J.W. and Kemp, B.E. (2009) Structure and function of AMP-activated protein kinase. Acta Physiol. (Oxf), 196, 3-14.
-
(2009)
Acta Physiol. (Oxf)
, vol.196
, pp. 3-14
-
-
Oakhill, J.S.1
Scott, J.W.2
Kemp, B.E.3
-
14
-
-
0034773404
-
Role of AMPactivated protein kinase in mechanism of metformin action
-
Zhou, G.; Myers, R.; Li, Y.; Chen, Y.; Shen, X.; Fenyk-Melody, J.; Wu, M.; Ventre, J.; Doebber, T.; Fujii, N.; Musi, N.; Hirshman, M.F.; Goodyear, L.J. and Moller, D.E. (2001) Role of AMPactivated protein kinase in mechanism of metformin action. J. Clin. Invest., 108, 1167-1174.
-
(2001)
J. Clin. Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
-
15
-
-
63849224233
-
AMPK activators-- potential therapeutics for metabolic and other diseases
-
Zhou, G.; Sebhat, I.K. and Zhang, B.B. (2009) AMPK activators-- potential therapeutics for metabolic and other diseases. Acta Physiol. (Oxf)., 196, 175-190.
-
(2009)
Acta Physiol. (Oxf)
, vol.196
, pp. 175-190
-
-
Zhou, G.1
Sebhat, I.K.2
Zhang, B.B.3
-
16
-
-
71549144752
-
2-(3,4- Dihydro-2H-pyrrolium-1-yl)-3oxoindan-1-olate (DHPO), a novel, synthetic small molecule that alleviates insulin resistance and lipid abnormalities
-
Kandadi, M.R.; Rajanna, P.K.; Unnikrishnan, M.K.; Boddu, S.P.; Hua, Y.; Li, J.; Du, M.; Ren, J. and Sreejayan, N. (2010) 2-(3,4- Dihydro-2H-pyrrolium-1-yl)-3oxoindan-1-olate (DHPO), a novel, synthetic small molecule that alleviates insulin resistance and lipid abnormalities. Biochem. Pharmacol., 79, 623-631.
-
(2010)
Biochem. Pharmacol
, vol.79
, pp. 623-631
-
-
Kandadi, M.R.1
Rajanna, P.K.2
Unnikrishnan, M.K.3
Boddu, S.P.4
Hua, Y.5
Li, J.6
Du, M.7
Ren, J.8
Sreejayan, N.9
-
17
-
-
77953169046
-
Cellular bioenergetics as a target for obesity therapy
-
Tseng, Y.H.; Cypess, A.M. and Kahn, C.R. (2010) Cellular bioenergetics as a target for obesity therapy. Nat. Rev. Drug Discov., 9, 465-482.
-
(2010)
Nat. Rev. Drug Discov
, vol.9
, pp. 465-482
-
-
Tseng, Y.H.1
Cypess, A.M.2
Kahn, C.R.3
-
18
-
-
43049096860
-
The role of AMP-activated protein kinase in obesity
-
Kola, B.; Grossman, A.B. and Korbonits, M. (2008) The role of AMP-activated protein kinase in obesity. Front. Horm. Res., 36, 198-211.
-
(2008)
Front. Horm. Res
, vol.36
, pp. 198-211
-
-
Kola, B.1
Grossman, A.B.2
Korbonits, M.3
-
19
-
-
0029978799
-
Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise
-
Winder, W.W. and Hardie, D.G. (1996) Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am. J. Physiol., 270, E299-E304.
-
(1996)
Am. J. Physiol
, vol.270
-
-
Winder, W.W.1
Hardie, D.G.2
-
20
-
-
40849092782
-
Adenosine 5'-monophosphateactivated protein kinase regulation of fatty acid oxidation in skeletal muscle
-
Osler, M.E. and Zierath, J.R. (2008) Adenosine 5'-monophosphateactivated protein kinase regulation of fatty acid oxidation in skeletal muscle. Endocrinology, 149, 935-941.
-
(2008)
Endocrinology
, vol.149
, pp. 935-941
-
-
Osler, M.E.1
Zierath, J.R.2
-
21
-
-
0031009673
-
Contractioninduced changes in acetyl-CoA carboxylase and 5'-AMP-activated kinase in skeletal muscle
-
Vavvas, D.; Apazidis, A.; Saha, A.K.; Gamble, J.; Patel, A.; Kemp, B.E.; Witters, L.A. and Ruderman, N.B. (1997) Contractioninduced changes in acetyl-CoA carboxylase and 5'-AMP-activated kinase in skeletal muscle. J. Biol. Chem., 272, 13255-13261.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 13255-13261
-
-
Vavvas, D.1
Apazidis, A.2
Saha, A.K.3
Gamble, J.4
Patel, A.5
Kemp, B.E.6
Witters, L.A.7
Ruderman, N.B.8
-
22
-
-
2942722769
-
Metabolic flexibility
-
Storlien, L.; Oakes, N.D. and Kelley, D.E. (2004) Metabolic flexibility. Proc. Nutr. Soc., 63, 363-368.
-
(2004)
Proc. Nutr. Soc
, vol.63
, pp. 363-368
-
-
Storlien, L.1
Oakes, N.D.2
Kelley, D.E.3
-
23
-
-
0034076660
-
Fuel selection in human skeletal muscle in insulin resistance: A reexamination
-
Kelley, D.E. and Mandarino, L.J. (2000) Fuel selection in human skeletal muscle in insulin resistance: a reexamination. Diabetes, 49, 677-683.
-
(2000)
Diabetes
, vol.49
, pp. 677-683
-
-
Kelley, D.E.1
Mandarino, L.J.2
-
24
-
-
73349119690
-
Cannabinoid type 1 receptor blockade induces transdifferentiation towards a brown fat phenotype in white adipocytes
-
Perwitz, N.; Wenzel, J.; Wagner, I.; Buning, J.; Drenckhan, M.; Zarse, K.; Ristow, M.; Lilienthal, W.; Lehnert, H. and Klein, J. (2010) Cannabinoid type 1 receptor blockade induces transdifferentiation towards a brown fat phenotype in white adipocytes. Diabetes Obes. Metab., 12, 158-166.
-
(2010)
Diabetes Obes. Metab
, vol.12
, pp. 158-166
-
-
Perwitz, N.1
Wenzel, J.2
Wagner, I.3
Buning, J.4
Drenckhan, M.5
Zarse, K.6
Ristow, M.7
Lilienthal, W.8
Lehnert, H.9
Klein, J.10
-
25
-
-
0033815967
-
Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase
-
Woods, A.; Azzout-Marniche, D.; Foretz, M.; Stein, S.C.; Lemarchand, P.; Ferre, P.; Foufelle, F. and Carling, D. (2000) Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. Mol. Cell Biol., 20, 6704-6711.
-
(2000)
Mol. Cell Biol
, vol.20
, pp. 6704-6711
-
-
Woods, A.1
Azzout-Marniche, D.2
Foretz, M.3
Stein, S.C.4
Lemarchand, P.5
Ferre, P.6
Foufelle, F.7
Carling, D.8
-
26
-
-
20844451123
-
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
-
Kahn, B.B.; Alquier, T.; Carling, D. and Hardie, D.G. (2005) AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab., 1, 15-25.
-
(2005)
Cell Metab
, vol.1
, pp. 15-25
-
-
Kahn, B.B.1
Alquier, T.2
Carling, D.3
Hardie, D.G.4
-
27
-
-
33847720313
-
Hypothalamic fatty acid metabolism: A housekeeping pathway that regulates food intake
-
Lopez, M.; Lelliott, C.J. and Vidal-Puig, A. (2007) Hypothalamic fatty acid metabolism: a housekeeping pathway that regulates food intake. Bioessays, 29, 248-261.
-
(2007)
Bioessays
, vol.29
, pp. 248-261
-
-
Lopez, M.1
Lelliott, C.J.2
Vidal-Puig, A.3
-
28
-
-
0031425839
-
AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle
-
Merrill, G.F.; Kurth, E.J.; Hardie, D.G. and Winder, W.W. (1997) AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. Am. J. Physiol., 273, E1107-1112.
-
(1997)
Am. J. Physiol
, vol.273
-
-
Merrill, G.F.1
Kurth, E.J.2
Hardie, D.G.3
Winder, W.W.4
-
29
-
-
77953916891
-
Differences in AMPK expression between subcutaneous and visceral adipose tissue in morbid obesity
-
Martinez-Agustin, O.; Hernandez-Morante, J.J.; Martinez-Plata, E.; Sanchez de Medina, F. and Garaulet, M. (2010) Differences in AMPK expression between subcutaneous and visceral adipose tissue in morbid obesity. Regul. Pept., 163, 31-36.
-
(2010)
Regul. Pept
, vol.163
, pp. 31-36
-
-
Martinez-Agustin, O.1
Hernandez-Morante, J.J.2
Martinez-Plata, E.3
de Medina, S.F.4
Garaulet, M.5
-
30
-
-
85047689953
-
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?
-
Corton, J.M.; Gillespie, J.G.; Hawley, S.A. and Hardie, D.G. (1995) 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? Eur. J. Biochem., 229, 558-565.
-
(1995)
Eur. J. Biochem
, vol.229
, pp. 558-565
-
-
Corton, J.M.1
Gillespie, J.G.2
Hawley, S.A.3
Hardie, D.G.4
-
31
-
-
21644455008
-
Antilipolytic action of AMP-activated protein kinase in rodent adipocytes
-
Daval, M.; Diot-Dupuy, F.; Bazin, R.; Hainault, I.; Viollet, B.; Vaulont, S.; Hajduch, E.; Ferre, P. and Foufelle, F. (2005) Antilipolytic action of AMP-activated protein kinase in rodent adipocytes. J. Biol. Chem., 280, 25250-25257.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 25250-25257
-
-
Daval, M.1
Diot-Dupuy, F.2
Bazin, R.3
Hainault, I.4
Viollet, B.5
Vaulont, S.6
Hajduch, E.7
Ferre, P.8
Foufelle, F.9
-
32
-
-
0036386911
-
Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle
-
Terada, S.; Goto, M.; Kato, M.; Kawanaka, K.; Shimokawa, T. and Tabata, I. (2002) Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle. Biochem. Biophys. Res. Commun., 296, 350-354.
-
(2002)
Biochem. Biophys. Res. Commun
, vol.296
, pp. 350-354
-
-
Terada, S.1
Goto, M.2
Kato, M.3
Kawanaka, K.4
Shimokawa, T.5
Tabata, I.6
-
33
-
-
0037058977
-
AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
-
Zong, H.; Ren, J.M.; Young, L.H.; Pypaert, M.; Mu, J.; Birnbaum, M.J. and Shulman, G.I. (2002) AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation. Proc. Natl. Acad. Sci. USA, 99, 15983-15987.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 15983-15987
-
-
Zong, H.1
Ren, J.M.2
Young, L.H.3
Pypaert, M.4
Mu, J.5
Birnbaum, M.J.6
Shulman, G.I.7
-
34
-
-
75749104187
-
AMPK as a mediator of hormonal signalling
-
Lim, C.T.; Kola, B. and Korbonits, M. (2010) AMPK as a mediator of hormonal signalling. J. Mol. Endocrinol., 44, 87-97.
-
(2010)
J. Mol. Endocrinol
, vol.44
, pp. 87-97
-
-
Lim, C.T.1
Kola, B.2
Korbonits, M.3
-
35
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
Minokoshi, Y.; Alquier, T.; Furukawa, N.; Kim, Y.B.; Lee, A.; Xue, B.; Mu, J.; Foufelle, F.; Ferre, P.; Birnbaum, M.J.; Stuck, B.J. and Kahn, B.B. (2004) AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature, 428, 569-574.
-
(2004)
Nature
, vol.428
, pp. 569-574
-
-
Minokoshi, Y.1
Alquier, T.2
Furukawa, N.3
Kim, Y.B.4
Lee, A.5
Xue, B.6
Mu, J.7
Foufelle, F.8
Ferre, P.9
Birnbaum, M.J.10
Stuck, B.J.11
Kahn, B.B.12
-
36
-
-
33745204479
-
AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues
-
Xue, B. and Kahn, B.B. (2006) AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues. J. Physiol., 574, 73-83.
-
(2006)
J. Physiol
, vol.574
, pp. 73-83
-
-
Xue, B.1
Kahn, B.B.2
-
37
-
-
66649088029
-
Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling
-
Hayes, M.R.; Bradley, L. and Grill, H.J. (2009) Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling. Endocrinology, 150, 2654-2659.
-
(2009)
Endocrinology
, vol.150
, pp. 2654-2659
-
-
Hayes, M.R.1
Bradley, L.2
Grill, H.J.3
-
38
-
-
78650913170
-
A New Role for a Metabolic Star: AMP-Activated Protein Kinase Stimulates Fat Absorption
-
Ferré, P. and Foufelle, F. (2011) A New Role for a Metabolic Star: AMP-Activated Protein Kinase Stimulates Fat Absorption. Cell metabolism, 13, 1-2.
-
(2011)
Cell Metabolism
, vol.13
, pp. 1-2
-
-
Ferré, P.1
Foufelle, F.2
-
39
-
-
73649128543
-
AMPK beta1 deletion reduces appetite, preventing obesity and hepatic insulin resistance
-
Dzamko, N.; van Denderen, B.J.; Hevener, A.L.; Jorgensen, S.B.; Honeyman, J.; Galic, S.; Chen, Z.P.; Watt, M.J.; Campbell, D.J.; Steinberg, G.R. and Kemp, B.E. (2010) AMPK beta1 deletion reduces appetite, preventing obesity and hepatic insulin resistance. J. Biol. Chem., 285, 115-122.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 115-122
-
-
Dzamko, N.1
van Denderen, B.J.2
Hevener, A.L.3
Jorgensen, S.B.4
Honeyman, J.5
Galic, S.6
Chen, Z.P.7
Watt, M.J.8
Campbell, D.J.9
Steinberg, G.R.10
Kemp, B.E.11
-
40
-
-
30544444653
-
Smoking status, cigarettes per day, and their relationship to overweight and obesity among former and current smokers in a national adult general population sample
-
John, U.; Hanke, M.; Rumpf, H.J. and Thyrian, J.R. (2005) Smoking status, cigarettes per day, and their relationship to overweight and obesity among former and current smokers in a national adult general population sample. Int. J. Obes. (Lond), 29, 1289-1294.
-
(2005)
Int. J. Obes. (Lond)
, vol.29
, pp. 1289-1294
-
-
John, U.1
Hanke, M.2
Rumpf, H.J.3
Thyrian, J.R.4
-
41
-
-
34848880141
-
Nicotine-induced activation of AMP-activated protein kinase inhibits fatty acid synthase in 3T3L1 adipocytes: A role for oxidant stress
-
An, Z.; Wang, H.; Song, P.; Zhang, M.; Geng, X. and Zou, M.H. (2007) Nicotine-induced activation of AMP-activated protein kinase inhibits fatty acid synthase in 3T3L1 adipocytes: a role for oxidant stress. J. Biol. Chem., 282, 26793-26801.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 26793-26801
-
-
An, Z.1
Wang, H.2
Song, P.3
Zhang, M.4
Geng, X.5
Zou, M.H.6
-
42
-
-
9044219848
-
A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. rhCNTF ALS Study Group
-
Miller, R.G.; Petajan, J.H.; Bryan, W.W.; Armon, C.; Barohn, R.J.; Goodpasture, J.C.; Hoagland, R.J.; Parry, G.J.; Ross, M.A. and Stromatt, S.C. (1996) A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. rhCNTF ALS Study Group. Ann. Neurol., 39, 256-260.
-
(1996)
Ann. Neurol
, vol.39
, pp. 256-260
-
-
Miller, R.G.1
Petajan, J.H.2
Bryan, W.W.3
Armon, C.4
Barohn, R.J.5
Goodpasture, J.C.6
Hoagland, R.J.7
Parry, G.J.8
Ross, M.A.9
Stromatt, S.C.10
-
43
-
-
33746037555
-
Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice
-
Steinberg, G.R.; Watt, M.J.; Fam, B.C.; Proietto, J.; Andrikopoulos, S.; Allen, A.M.; Febbraio, M.A. and Kemp, B.E. (2006) Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice. Endocrinology, 147, 3906-3914.
-
(2006)
Endocrinology
, vol.147
, pp. 3906-3914
-
-
Steinberg, G.R.1
Watt, M.J.2
Fam, B.C.3
Proietto, J.4
Andrikopoulos, S.5
Allen, A.M.6
Febbraio, M.A.7
Kemp, B.E.8
-
44
-
-
33846542071
-
Mechanisms underlying the resistance to dietinduced obesity in germ-free mice
-
Backhed, F.; Manchester, J.K.; Semenkovich, C.F. and Gordon, J.I. (2007) Mechanisms underlying the resistance to dietinduced obesity in germ-free mice. Proc. Natl. Acad. Sci. USA, 104, 979-984.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 979-984
-
-
Backhed, F.1
Manchester, J.K.2
Semenkovich, C.F.3
Gordon, J.I.4
-
45
-
-
0033400310
-
Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
-
Kelley, D.E.; Goodpaster, B.; Wing, R.R. and Simoneau, J.A. (1999) Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss. Am. J. Physiol., 277, E1130-E1141.
-
(1999)
Am. J. Physiol
, vol.277
-
-
Kelley, D.E.1
Goodpaster, B.2
Wing, R.R.3
Simoneau, J.A.4
-
46
-
-
1642377274
-
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
-
Petersen, K.F.; Dufour, S.; Befroy, D.; Garcia, R. and Shulman, G.I. (2004) Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N. Engl. J. Med., 350, 664-671.
-
(2004)
N. Engl. J. Med
, vol.350
, pp. 664-671
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Garcia, R.4
Shulman, G.I.5
-
47
-
-
37449020075
-
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
-
Koves, T.R.; Ussher, J.R.; Noland, R.C.; Slentz, D.; Mosedale, M.; Ilkayeva, O.; Bain, J.; Stevens, R.; Dyck, J.R.; Newgard, C.B.; Lopaschuk, G.D. and Muoio, D.M. (2008) Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab., 7, 45-56.
-
(2008)
Cell Metab
, vol.7
, pp. 45-56
-
-
Koves, T.R.1
Ussher, J.R.2
Noland, R.C.3
Slentz, D.4
Mosedale, M.5
Ilkayeva, O.6
Bain, J.7
Stevens, R.8
Dyck, J.R.9
Newgard, C.B.10
Lopaschuk, G.D.11
Muoio, D.M.12
-
48
-
-
0034074153
-
5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase
-
Lochhead, P.A.; Salt, I.P.; Walker, K.S.; Hardie, D.G. and Sutherland, C. (2000) 5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase. Diabetes, 49, 896-903.
-
(2000)
Diabetes
, vol.49
, pp. 896-903
-
-
Lochhead, P.A.1
Salt, I.P.2
Walker, K.S.3
Hardie, D.G.4
Sutherland, C.5
-
49
-
-
57749094239
-
AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver
-
Horike, N.; Sakoda, H.; Kushiyama, A.; Ono, H.; Fujishiro, M.; Kamata, H.; Nishiyama, K.; Uchijima, Y.; Kurihara, Y.; Kurihara, H. and Asano, T. (2008) AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver. J. Biol. Chem., 283, 33902-33910.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 33902-33910
-
-
Horike, N.1
Sakoda, H.2
Kushiyama, A.3
Ono, H.4
Fujishiro, M.5
Kamata, H.6
Nishiyama, K.7
Uchijima, Y.8
Kurihara, Y.9
Kurihara, H.10
Asano, T.11
-
50
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi, T.; Kamon, J.; Minokoshi, Y.; Ito, Y.; Waki, H.; Uchida, S.; Yamashita, S.; Noda, M.; Kita, S.; Ueki, K.; Eto, K.; Akanuma, Y.; Froguel, P.; Foufelle, F.; Ferre, P.; Carling, D.; Kimura, S.; Nagai, R.; Kahn, B.B. and Kadowaki, T. (2002) Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat. Med., 8, 1288-1295.
-
(2002)
Nat. Med
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
Ito, Y.4
Waki, H.5
Uchida, S.6
Yamashita, S.7
Noda, M.8
Kita, S.9
Ueki, K.10
Eto, K.11
Akanuma, Y.12
Froguel, P.13
Foufelle, F.14
Ferre, P.15
Carling, D.16
Kimura, S.17
Nagai, R.18
Kahn, B.B.19
Kadowaki, T.20
more..
-
51
-
-
0035029874
-
Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats
-
Bergeron, R.; Previs, S.F.; Cline, G.W.; Perret, P.; Russell, R.R., 3rd; Young, L.H. and Shulman, G.I. (2001) Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats. Diabetes, 50, 1076-1082.
-
(2001)
Diabetes
, vol.50
, pp. 1076-1082
-
-
Bergeron, R.1
Previs, S.F.2
Cline, G.W.3
Perret, P.4
Russell 3rd, R.R.5
Young, L.H.6
Shulman, G.I.7
-
52
-
-
0033673203
-
Mechanism by which metformin reduces glucose production in type 2 diabetes
-
Hundal, R.S.; Krssak, M.; Dufour, S.; Laurent, D.; Lebon, V.; Chandramouli, V.; Inzucchi, S.E.; Schumann, W.C.; Petersen, K.F.; Landau, B.R. and Shulman, G.I. (2000) Mechanism by which metformin reduces glucose production in type 2 diabetes. Diabetes, 49, 2063-2069.
-
(2000)
Diabetes
, vol.49
, pp. 2063-2069
-
-
Hundal, R.S.1
Krssak, M.2
Dufour, S.3
Laurent, D.4
Lebon, V.5
Chandramouli, V.6
Inzucchi, S.E.7
Schumann, W.C.8
Petersen, K.F.9
Landau, B.R.10
Shulman, G.I.11
-
53
-
-
28844433635
-
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
Shaw, R.J.; Lamia, K.A.; Vasquez, D.; Koo, S.H.; Bardeesy, N.; Depinho, R.A.; Montminy, M. and Cantley, L.C. (2005) The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science, 310, 1642-1646.
-
(2005)
Science
, vol.310
, pp. 1642-1646
-
-
Shaw, R.J.1
Lamia, K.A.2
Vasquez, D.3
Koo, S.H.4
Bardeesy, N.5
Depinho, R.A.6
Montminy, M.7
Cantley, L.C.8
-
54
-
-
0033559856
-
AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: Evidence that sn-glycerol-3-phosphate acyltransferase is a novel target
-
Muoio, D.M.; Seefeld, K.; Witters, L.A. and Coleman, R.A. (1999) AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. Biochem. J., 338, 783-791.
-
(1999)
Biochem. J
, vol.338
, pp. 783-791
-
-
Muoio, D.M.1
Seefeld, K.2
Witters, L.A.3
Coleman, R.A.4
-
55
-
-
48449094498
-
AMPK and PPARdelta agonists are exercise mimetics
-
Narkar, V.A.; Downes, M.; Yu, R.T.; Embler, E.; Wang, Y.X.; Banayo, E.; Mihaylova, M.M.; Nelson, M.C.; Zou, Y.; Juguilon, H.; Kang, H.; Shaw, R.J. and Evans, R.M. (2008) AMPK and PPARdelta agonists are exercise mimetics. Cell, 134, 405-415.
-
(2008)
Cell
, vol.134
, pp. 405-415
-
-
Narkar, V.A.1
Downes, M.2
Yu, R.T.3
Embler, E.4
Wang, Y.X.5
Banayo, E.6
Mihaylova, M.M.7
Nelson, M.C.8
Zou, Y.9
Juguilon, H.10
Kang, H.11
Shaw, R.J.12
Evans, R.M.13
-
56
-
-
33847399214
-
Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: A time-course and dose-response study
-
Sriwijitkamol, A.; Coletta, D.K.; Wajcberg, E.; Balbontin, G.B.; Reyna, S.M.; Barrientes, J.; Eagan, P.A.; Jenkinson, C.P.; Cersosimo, E.; DeFronzo, R.A.; Sakamoto, K. and Musi, N. (2007) Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study. Diabetes, 56, 836-848.
-
(2007)
Diabetes
, vol.56
, pp. 836-848
-
-
Sriwijitkamol, A.1
Coletta, D.K.2
Wajcberg, E.3
Balbontin, G.B.4
Reyna, S.M.5
Barrientes, J.6
Eagan, P.A.7
Jenkinson, C.P.8
Cersosimo, E.9
Defronzo, R.A.10
Sakamoto, K.11
Musi, N.12
-
57
-
-
40449094269
-
Insulin-resistant muscle is exercise resistant: Evidence for reduced response of nuclearencoded mitochondrial genes to exercise
-
De Filippis, E.; Alvarez, G.; Berria, R.; Cusi, K.; Everman, S.; Meyer, C. and Mandarino, L.J. (2008) Insulin-resistant muscle is exercise resistant: evidence for reduced response of nuclearencoded mitochondrial genes to exercise. Am. J. Physiol. Endocrinol. Metab., 294, E607-E614.
-
(2008)
Am. J. Physiol. Endocrinol. Metab
, vol.294
-
-
de Filippis, E.1
Alvarez, G.2
Berria, R.3
Cusi, K.4
Everman, S.5
Meyer, C.6
Mandarino, L.J.7
-
58
-
-
0242600806
-
5-aminoimidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes
-
Koistinen, H.A.; Galuska, D.; Chibalin, A.V.; Yang, J.; Zierath, J.R.; Holman, G.D. and Wallberg-Henriksson, H. (2003) 5-aminoimidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes. Diabetes, 52, 1066-1072.
-
(2003)
Diabetes
, vol.52
, pp. 1066-1072
-
-
Koistinen, H.A.1
Galuska, D.2
Chibalin, A.V.3
Yang, J.4
Zierath, J.R.5
Holman, G.D.6
Wallberg-Henriksson, H.7
-
59
-
-
0345374578
-
Minireview: Malonyl CoA, AMP-activated protein kinase, and adiposity
-
Ruderman, N.B.; Saha, A.K. and Kraegen, E.W. (2003) Minireview: malonyl CoA, AMP-activated protein kinase, and adiposity. Endocrinology, 144, 5166-5171.
-
(2003)
Endocrinology
, vol.144
, pp. 5166-5171
-
-
Ruderman, N.B.1
Saha, A.K.2
Kraegen, E.W.3
-
60
-
-
0042423598
-
Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles
-
Suwa, M.; Nakano, H. and Kumagai, S. (2003) Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles. J. Appl. Physiol., 95, 960-968.
-
(2003)
J. Appl. Physiol
, vol.95
, pp. 960-968
-
-
Suwa, M.1
Nakano, H.2
Kumagai, S.3
-
61
-
-
34547545892
-
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
-
Jager, S.; Handschin, C.; St-Pierre, J. and Spiegelman, B.M. (2007) AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc. Natl. Acad. Sci. USA, 104, 12017-12022.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 12017-12022
-
-
Jager, S.1
Handschin, C.2
St-Pierre, J.3
Spiegelman, B.M.4
-
62
-
-
0032704115
-
Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle
-
Holmes, B.F.; Kurth-Kraczek, E.J. and Winder, W.W. (1999) Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle. J. Appl. Physiol., 87, 1990-1995.
-
(1999)
J. Appl. Physiol
, vol.87
, pp. 1990-1995
-
-
Holmes, B.F.1
Kurth-Kraczek, E.J.2
Winder, W.W.3
-
63
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
-
Kelley, D.E.; He, J.; Menshikova, E.V. and Ritov, V.B. (2002) Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes, 51, 2944-2950.
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
64
-
-
67349276169
-
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
-
Canto, C.; Gerhart-Hines, Z.; Feige, J.N.; Lagouge, M.; Noriega, L.; Milne, J.C.; Elliott, P.J.; Puigserver, P. and Auwerx, J. (2009) AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature, 458, 1056-1060.
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Canto, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
Puigserver, P.8
Auwerx, J.9
-
65
-
-
79955993481
-
Role of AMP-activated Protein Kinase and Adiponectin during Development of Hepatic Steatosis in High-fat Diet-induced Obesity in Rats
-
Ha, S.K.; Kim, J. and Chae, C. (2011) Role of AMP-activated Protein Kinase and Adiponectin during Development of Hepatic Steatosis in High-fat Diet-induced Obesity in Rats. J. Comp. Pathol., 145, 88-94.
-
(2011)
J. Comp. Pathol
, vol.145
, pp. 88-94
-
-
Ha, S.K.1
Kim, J.2
Chae, C.3
-
66
-
-
33846365989
-
Metabolic syndrome and risk of incident cardiovascular events and death: A systematic review and meta-analysis of longitudinal studies
-
Gami, A.S.; Witt, B.J.; Howard, D.E.; Erwin, P.J.; Gami, L.A.; Somers, V.K. and Montori, V.M. (2007) Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies. J. Am. Coll. Cardiol., 49, 403-414.
-
(2007)
J. Am. Coll. Cardiol
, vol.49
, pp. 403-414
-
-
Gami, A.S.1
Witt, B.J.2
Howard, D.E.3
Erwin, P.J.4
Gami, L.A.5
Somers, V.K.6
Montori, V.M.7
-
67
-
-
0029093341
-
High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl- CoA levels due to an increase in 5'-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase
-
Kudo, N.; Barr, A.J.; Barr, R.L.; Desai, S. and Lopaschuk, G.D. (1995) High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl- CoA levels due to an increase in 5'-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase. J. Biol. Chem., 270, 17513-17520.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 17513-17520
-
-
Kudo, N.1
Barr, A.J.2
Barr, R.L.3
Desai, S.4
Lopaschuk, G.D.5
-
68
-
-
78149279712
-
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
-
Russell, R.R., 3rd; Li, J.; Coven, D.L.; Pypaert, M.; Zechner, C.; Palmeri, M.; Giordano, F.J.; Mu, J.; Birnbaum, M.J. and Young, L.H. (2004) AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J. Clin. Invest., 114, 495-503.
-
(2004)
J. Clin. Invest
, vol.114
, pp. 495-503
-
-
Russell 3rd, R.R.1
Li, J.2
Coven, D.L.3
Pypaert, M.4
Zechner, C.5
Palmeri, M.6
Giordano, F.J.7
Mu, J.8
Birnbaum, M.J.9
Young, L.H.10
-
69
-
-
0034687210
-
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
-
Marsin, A.S.; Bertrand, L.; Rider, M.H.; Deprez, J.; Beauloye, C.; Vincent, M.F.; Van den Berghe, G.; Carling, D. and Hue, L. (2000) Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia. Curr. Biol., 10, 1247-1255.
-
(2000)
Curr. Biol
, vol.10
, pp. 1247-1255
-
-
Marsin, A.S.1
Bertrand, L.2
Rider, M.H.3
Deprez, J.4
Beauloye, C.5
Vincent, M.F.6
van den Berghe, G.7
Carling, D.8
Hue, L.9
-
70
-
-
0032881635
-
Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR
-
Russell, R.R., 3rd; Bergeron, R.; Shulman, G.I. and Young, L.H. (1999) Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR. Am. J. Physiol., 277, H643-649.
-
(1999)
Am. J. Physiol
, vol.277
-
-
Russell 3rd, R.R.1
Bergeron, R.2
Shulman, G.I.3
Young, L.H.4
-
71
-
-
33646812555
-
Long-term metformin treatment stimulates cardiomyocyte glucose transport through an AMP-activated protein kinase-dependent reduction in GLUT4 endocytosis
-
Yang, J. and Holman, G.D. (2006) Long-term metformin treatment stimulates cardiomyocyte glucose transport through an AMP-activated protein kinase-dependent reduction in GLUT4 endocytosis. Endocrinology, 147, 2728-2736.
-
(2006)
Endocrinology
, vol.147
, pp. 2728-2736
-
-
Yang, J.1
Holman, G.D.2
-
72
-
-
67651236746
-
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases myocardial glucose uptake during reperfusion and induces late pre-conditioning: Potential role of AMP-activated protein kinase
-
Kristiansen, S.B.; Solskov, L.; Jessen, N.; Lofgren, B.; Schmitz, O.; Nielsen-Kudsk, J.E.; Nielsen, T.T.; Botker, H.E. and Lund, S. (2009) 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases myocardial glucose uptake during reperfusion and induces late pre-conditioning: potential role of AMP-activated protein kinase. Basic Clin. Pharmacol. Toxicol., 105, 10-16.
-
(2009)
Basic Clin. Pharmacol. Toxicol
, vol.105
, pp. 10-16
-
-
Kristiansen, S.B.1
Solskov, L.2
Jessen, N.3
Lofgren, B.4
Schmitz, O.5
Nielsen-Kudsk, J.E.6
Nielsen, T.T.7
Botker, H.E.8
Lund, S.9
-
73
-
-
40949087724
-
Acute metformin therapy confers cardioprotection against myocardial infarction via AMPKeNOS- mediated signaling
-
Calvert, J.W.; Gundewar, S.; Jha, S.; Greer, J.J.; Bestermann, W.H.; Tian, R. and Lefer, D.J. (2008) Acute metformin therapy confers cardioprotection against myocardial infarction via AMPKeNOS- mediated signaling. Diabetes, 57, 696-705.
-
(2008)
Diabetes
, vol.57
, pp. 696-705
-
-
Calvert, J.W.1
Gundewar, S.2
Jha, S.3
Greer, J.J.4
Bestermann, W.H.5
Tian, R.6
Lefer, D.J.7
-
74
-
-
11144261702
-
The metabolic switch AMPK regulates cardiac heparin-releasable lipoprotein lipase
-
An, D.; Pulinilkunnil, T.; Qi, D.; Ghosh, S.; Abrahani, A. and Rodrigues, B. (2005) The metabolic switch AMPK regulates cardiac heparin-releasable lipoprotein lipase. Am. J. Physiol. Endocrinol. Metab., 288, E246-E253.
-
(2005)
Am. J. Physiol. Endocrinol. Metab
, vol.288
-
-
An, D.1
Pulinilkunnil, T.2
Qi, D.3
Ghosh, S.4
Abrahani, A.5
Rodrigues, B.6
-
75
-
-
41549084644
-
AMP-activated protein kinase activation by 5- aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) inhibits palmitate-induced endothelial cell apoptosis through reactive oxygen species suppression
-
Kim, J.E.; Kim, Y.W.; Lee, I.K.; Kim, J.Y.; Kang, Y.J. and Park, S.Y. (2008) AMP-activated protein kinase activation by 5- aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) inhibits palmitate-induced endothelial cell apoptosis through reactive oxygen species suppression. J. Pharmacol. Sci., 106, 394-403.
-
(2008)
J. Pharmacol. Sci
, vol.106
, pp. 394-403
-
-
Kim, J.E.1
Kim, Y.W.2
Lee, I.K.3
Kim, J.Y.4
Kang, Y.J.5
Park, S.Y.6
-
76
-
-
78649909203
-
Does long-term metformin treatment increase cardiac lipoprotein lipase?
-
Hauton, D. (2010) Does long-term metformin treatment increase cardiac lipoprotein lipase? Metabolism, 60, 32-42.
-
(2010)
Metabolism
, vol.60
, pp. 32-42
-
-
Hauton, D.1
-
77
-
-
38749137749
-
Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
-
Miller, E.J.; Li, J.; Leng, L.; McDonald, C.; Atsumi, T.; Bucala, R. and Young, L.H. (2008) Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature, 451, 578-582.
-
(2008)
Nature
, vol.451
, pp. 578-582
-
-
Miller, E.J.1
Li, J.2
Leng, L.3
McDonald, C.4
Atsumi, T.5
Bucala, R.6
Young, L.H.7
-
78
-
-
77954959087
-
Impaired macrophage migration inhibitory factor-AMP activated protein kinase activation and ischemic recovery in the senescent heart
-
Ma, H.; Wang, J.; Thomas, D.P.; Tong, C.; Leng, L.; Wang, W.; Merk, M.; Zierow, S.; Bernhagen, J.; Ren, J.; Bucala, R. and Li, J. (2010) Impaired macrophage migration inhibitory factor-AMP activated protein kinase activation and ischemic recovery in the senescent heart. Circulation, 122, 282-292.
-
(2010)
Circulation
, vol.122
, pp. 282-292
-
-
Ma, H.1
Wang, J.2
Thomas, D.P.3
Tong, C.4
Leng, L.5
Wang, W.6
Merk, M.7
Zierow, S.8
Bernhagen, J.9
Ren, J.10
Bucala, R.11
Li, J.12
-
79
-
-
61949300140
-
Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure
-
Gundewar, S.; Calvert, J.W.; Jha, S.; Toedt-Pingel, I.; Ji, S.Y.; Nunez, D.; Ramachandran, A.; Anaya-Cisneros, M.; Tian, R. and Lefer, D.J. (2009) Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure. Circ. Res., 104, 403-411.
-
(2009)
Circ. Res
, vol.104
, pp. 403-411
-
-
Gundewar, S.1
Calvert, J.W.2
Jha, S.3
Toedt-Pingel, I.4
Ji, S.Y.5
Nunez, D.6
Ramachandran, A.7
Anaya-Cisneros, M.8
Tian, R.9
Lefer, D.J.10
-
80
-
-
27144457438
-
Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms
-
Shibata, R.; Sato, K.; Pimentel, D.R.; Takemura, Y.; Kihara, S.; Ohashi, K.; Funahashi, T.; Ouchi, N. and Walsh, K. (2005) Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat. Med., 11, 1096-1103.
-
(2005)
Nat. Med
, vol.11
, pp. 1096-1103
-
-
Shibata, R.1
Sato, K.2
Pimentel, D.R.3
Takemura, Y.4
Kihara, S.5
Ohashi, K.6
Funahashi, T.7
Ouchi, N.8
Walsh, K.9
-
81
-
-
33745204925
-
AMPK alterations in cardiac physiology and pathology: Enemy or ally
-
Dyck, J.R. and Lopaschuk, G.D. (2006) AMPK alterations in cardiac physiology and pathology: enemy or ally? J. Physiol., 574, 95-112.
-
(2006)
J. Physiol
, vol.574
, pp. 95-112
-
-
Dyck, J.R.1
Lopaschuk, G.D.2
-
82
-
-
0031045198
-
Free fatty acid metabolism during myocardial ischemia and reperfusion
-
Hendrickson, S.C.; St Louis, J.D.; Lowe, J.E. and Abdel-aleem, S. (1997) Free fatty acid metabolism during myocardial ischemia and reperfusion. Mol. Cell Biochem., 166, 85-94.
-
(1997)
Mol. Cell Biochem
, vol.166
, pp. 85-94
-
-
Hendrickson, S.C.1
Louis St., J.D.2
Lowe, J.E.3
Abdel-Aleem, S.4
-
83
-
-
0025277333
-
Energy substrate utilization by isolated working hearts from newborn rabbits
-
Lopaschuk, G.D. and Spafford, M.A. (1990) Energy substrate utilization by isolated working hearts from newborn rabbits. Am. J. Physiol., 258, H1274-1280.
-
(1990)
Am. J. Physiol
, vol.258
-
-
Lopaschuk, G.D.1
Spafford, M.A.2
-
84
-
-
0027372106
-
An imbalance between glycolysis and glucose oxidation is a possible explanation for the detrimental effects of high levels of fatty acids during aerobic reperfusion of ischemic hearts
-
Lopaschuk, G.D.; Wambolt, R.B. and Barr, R.L. (1993) An imbalance between glycolysis and glucose oxidation is a possible explanation for the detrimental effects of high levels of fatty acids during aerobic reperfusion of ischemic hearts. J. Pharmacol. Exp. Ther., 264, 135-144.
-
(1993)
J. Pharmacol. Exp. Ther
, vol.264
, pp. 135-144
-
-
Lopaschuk, G.D.1
Wambolt, R.B.2
Barr, R.L.3
-
85
-
-
0030860259
-
Alterations in fatty acid oxidation during reperfusion of the heart after myocardial ischemia
-
Lopaschuk, G.D. (1997) Alterations in fatty acid oxidation during reperfusion of the heart after myocardial ischemia. Am. J. Cardiol., 80, 11A-16A.
-
(1997)
Am. J. Cardiol
, vol.80
-
-
Lopaschuk, G.D.1
-
86
-
-
4444226906
-
Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation
-
Dyck, J.R.; Cheng, J.F.; Stanley, W.C.; Barr, R.; Chandler, M.P.; Brown, S.; Wallace, D.; Arrhenius, T.; Harmon, C.; Yang, G.; Nadzan, A.M. and Lopaschuk, G.D. (2004) Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation. Circ. Res., 94, e78-84.
-
(2004)
Circ. Res
, vol.94
-
-
Dyck, J.R.1
Cheng, J.F.2
Stanley, W.C.3
Barr, R.4
Chandler, M.P.5
Brown, S.6
Wallace, D.7
Arrhenius, T.8
Harmon, C.9
Yang, G.10
Nadzan, A.M.11
Lopaschuk, G.D.12
-
87
-
-
79961039309
-
Targeting AMPK for cardiac protection: Opportunities and challenges
-
In Press, Corrected Proof
-
Kim, M. and Tian, R. (2011) Targeting AMPK for cardiac protection: Opportunities and challenges. J. Mol. Cell. Cardiol., In Press, Corrected Proof,
-
(2011)
J. Mol. Cell. Cardiol
-
-
Kim, M.1
Tian, R.2
-
88
-
-
0027930794
-
Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts
-
Allard, M.F.; Schonekess, B.O.; Henning, S.L.; English, D.R. and Lopaschuk, G.D. (1994) Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts. Am. J. Physiol., 267, H742-750.
-
(1994)
Am. J. Physiol
, vol.267
-
-
Allard, M.F.1
Schonekess, B.O.2
Henning, S.L.3
English, D.R.4
Lopaschuk, G.D.5
-
89
-
-
0041707843
-
Glucose metabolism and energy homeostasis in mouse hearts overexpressing dominant negative alpha2 subunit of AMP-activated protein kinase
-
Xing, Y.; Musi, N.; Fujii, N.; Zou, L.; Luptak, I.; Hirshman, M.F.; Goodyear, L.J. and Tian, R. (2003) Glucose metabolism and energy homeostasis in mouse hearts overexpressing dominant negative alpha2 subunit of AMP-activated protein kinase. J. Biol. Chem., 278, 28372-28377.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 28372-28377
-
-
Xing, Y.1
Musi, N.2
Fujii, N.3
Zou, L.4
Luptak, I.5
Hirshman, M.F.6
Goodyear, L.J.7
Tian, R.8
-
90
-
-
0035797839
-
Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy
-
Tian, R.; Musi, N.; D'Agostino, J.; Hirshman, M.F. and Goodyear, L.J. (2001) Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy. Circulation, 104, 1664-1669.
-
(2001)
Circulation
, vol.104
, pp. 1664-1669
-
-
Tian, R.1
Musi, N.2
D'Agostino, J.3
Hirshman, M.F.4
Goodyear, L.J.5
-
91
-
-
0036364274
-
Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMPactivated protein kinase and protein phosphatases in isolated hepatocytes
-
Krause, U.; Bertrand, L. and Hue, L. (2002) Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMPactivated protein kinase and protein phosphatases in isolated hepatocytes. Eur. J. Biochem., 269, 3751-3759.
-
(2002)
Eur. J. Biochem
, vol.269
, pp. 3751-3759
-
-
Krause, U.1
Bertrand, L.2
Hue, L.3
-
92
-
-
0037143449
-
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis
-
Horman, S.; Browne, G.; Krause, U.; Patel, J.; Vertommen, D.; Bertrand, L.; Lavoinne, A.; Hue, L.; Proud, C. and Rider, M. (2002) Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis. Curr. Biol., 12, 1419-1423.
-
(2002)
Curr. Biol
, vol.12
, pp. 1419-1423
-
-
Horman, S.1
Browne, G.2
Krause, U.3
Patel, J.4
Vertommen, D.5
Bertrand, L.6
Lavoinne, A.7
Hue, L.8
Proud, C.9
Rider, M.10
-
93
-
-
3543008912
-
Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte
-
Chan, A.Y.; Soltys, C.L.; Young, M.E.; Proud, C.G. and Dyck, J.R. (2004) Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte. J. Biol. Chem., 279, 32771-32779.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 32771-32779
-
-
Chan, A.Y.1
Soltys, C.L.2
Young, M.E.3
Proud, C.G.4
Dyck, J.R.5
-
94
-
-
72149093508
-
Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction
-
Ikeda, Y.; Sato, K.; Pimentel, D.R.; Sam, F.; Shaw, R.J.; Dyck, J.R. and Walsh, K. (2009) Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. J. Biol. Chem., 284, 35839-35849.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 35839-35849
-
-
Ikeda, Y.1
Sato, K.2
Pimentel, D.R.3
Sam, F.4
Shaw, R.J.5
Dyck, J.R.6
Walsh, K.7
-
95
-
-
79952070936
-
Deficiency in AMP-activated protein kinase exaggerates high fat diet-induced cardiac hypertrophy and contractile dysfunction
-
Turdi, S.; Kandadi, M.R.; Zhao, J.; Huff, A.F.; Du, M. and Ren, J. (2011) Deficiency in AMP-activated protein kinase exaggerates high fat diet-induced cardiac hypertrophy and contractile dysfunction. J. Mol. Cell. Cardiol., 150, 712-722.
-
(2011)
J. Mol. Cell. Cardiol
, vol.150
, pp. 712-722
-
-
Turdi, S.1
Kandadi, M.R.2
Zhao, J.3
Huff, A.F.4
Du, M.5
Ren, J.6
-
96
-
-
0035859215
-
Identification of a gene responsible for familial Wolff-Parkinson-White syndrome
-
Gollob, M.H.; Green, M.S.; Tang, A.S.; Gollob, T.; Karibe, A.; Ali Hassan, A.S.; Ahmad, F.; Lozado, R.; Shah, G.; Fananapazir, L.; Bachinski, L.L. and Roberts, R. (2001) Identification of a gene responsible for familial Wolff-Parkinson-White syndrome. N. Engl. J. Med., 344, 1823-1831.
-
(2001)
N. Engl. J. Med
, vol.344
, pp. 1823-1831
-
-
Gollob, M.H.1
Green, M.S.2
Tang, A.S.3
Gollob, T.4
Karibe, A.5
Ali, H.A.S.6
Ahmad, F.7
Lozado, R.8
Shah, G.9
Fananapazir, L.10
Bachinski, L.L.11
Roberts, R.12
-
97
-
-
33646397564
-
Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff-Parkinson-White syndrome
-
Davies, J.K.; Wells, D.J.; Liu, K.; Whitrow, H.R.; Daniel, T.D.; Grignani, R.; Lygate, C.A.; Schneider, J.E.; Noel, G.; Watkins, H. and Carling, D. (2006) Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff-Parkinson-White syndrome. Am. J. Physiol. Heart Circ. Physiol., 290, H1942-1951.
-
(2006)
Am. J. Physiol. Heart Circ. Physiol
, vol.290
-
-
Davies, J.K.1
Wells, D.J.2
Liu, K.3
Whitrow, H.R.4
Daniel, T.D.5
Grignani, R.6
Lygate, C.A.7
Schneider, J.E.8
Noel, G.9
Watkins, H.10
Carling, D.11
-
98
-
-
20044391423
-
Adenosine monophosphate-activated protein kinase disease mimicks hypertrophic cardiomyopathy and Wolff-Parkinson-White syndrome: Natural history
-
Murphy, R.T.; Mogensen, J.; McGarry, K.; Bahl, A.; Evans, A.; Osman, E.; Syrris, P.; Gorman, G.; Farrell, M.; Holton, J.L.; Hanna, M.G.; Hughes, S.; Elliott, P.M.; Macrae, C.A. and McKenna, W.J. (2005) Adenosine monophosphate-activated protein kinase disease mimicks hypertrophic cardiomyopathy and Wolff-Parkinson-White syndrome: natural history. J. Am. Coll. Cardiol., 45, 922-930.
-
(2005)
J. Am. Coll. Cardiol
, vol.45
, pp. 922-930
-
-
Murphy, R.T.1
Mogensen, J.2
McGarry, K.3
Bahl, A.4
Evans, A.5
Osman, E.6
Syrris, P.7
Gorman, G.8
Farrell, M.9
Holton, J.L.10
Hanna, M.G.11
Hughes, S.12
Elliott, P.M.13
Macrae, C.A.14
McKenna, W.J.15
-
99
-
-
74149091717
-
Activation of cardiac hypertrophic signaling pathways in a transgenic mouse with the human PRKAG2 Thr400Asn mutation
-
Banerjee, S.K.; McGaffin, K.R.; Huang, X.N. and Ahmad, F. (2010) Activation of cardiac hypertrophic signaling pathways in a transgenic mouse with the human PRKAG2 Thr400Asn mutation. Biochim. Biophys. Acta., 1802, 284-291.
-
(2010)
Biochim. Biophys. Acta
, vol.1802
, pp. 284-291
-
-
Banerjee, S.K.1
McGaffin, K.R.2
Huang, X.N.3
Ahmad, F.4
-
100
-
-
53049091294
-
Resveratrol inhibits cardiac hypertrophy via AMP-activated protein kinase and Akt
-
Chan, A.Y.; Dolinsky, V.W.; Soltys, C.L.; Viollet, B.; Baksh, S.; Light, P.E. and Dyck, J.R. (2008) Resveratrol inhibits cardiac hypertrophy via AMP-activated protein kinase and Akt. J. Biol. Chem., 283, 24194-24201.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 24194-24201
-
-
Chan, A.Y.1
Dolinsky, V.W.2
Soltys, C.L.3
Viollet, B.4
Baksh, S.5
Light, P.E.6
Dyck, J.R.7
-
101
-
-
65249183838
-
Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1
-
Dolinsky, V.W.; Chan, A.Y.; Robillard Frayne, I.; Light, P.E.; Des Rosiers, C. and Dyck, J.R. (2009) Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1. Circulation, 119, 1643-1652.
-
(2009)
Circulation
, vol.119
, pp. 1643-1652
-
-
Dolinsky, V.W.1
Chan, A.Y.2
Robillard, F.I.3
Light, P.E.4
des Rosiers, C.5
Dyck, J.R.6
-
102
-
-
66349105917
-
Metformin prevents progression of heart failure in dogs: Role of AMP-activated protein kinase
-
Sasaki, H.; Asanuma, H.; Fujita, M.; Takahama, H.; Wakeno, M.; Ito, S.; Ogai, A.; Asakura, M.; Kim, J.; Minamino, T.; Takashima, S.; Sanada, S.; Sugimachi, M.; Komamura, K.; Mochizuki, N. and Kitakaze, M. (2009) Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase. Circulation, 119, 2568-2577.
-
(2009)
Circulation
, vol.119
, pp. 2568-2577
-
-
Sasaki, H.1
Asanuma, H.2
Fujita, M.3
Takahama, H.4
Wakeno, M.5
Ito, S.6
Ogai, A.7
Asakura, M.8
Kim, J.9
Minamino, T.10
Takashima, S.11
Sanada, S.12
Sugimachi, M.13
Komamura, K.14
Mochizuki, N.15
Kitakaze, M.16
-
103
-
-
73949144065
-
Globular adiponectin inhibits angiotensin II-induced nuclear factor kappaB activation through AMP-activated protein kinase in cardiac hypertrophy
-
Wang, C.; Li, L.; Zhang, Z.G.; Fan, D.; Zhu, Y. and Wu, L.L. (2010) Globular adiponectin inhibits angiotensin II-induced nuclear factor kappaB activation through AMP-activated protein kinase in cardiac hypertrophy. J. Cell. Physiol., 222, 149-155.
-
(2010)
J. Cell. Physiol
, vol.222
, pp. 149-155
-
-
Wang, C.1
Li, L.2
Zhang, Z.G.3
Fan, D.4
Zhu, Y.5
Wu, L.L.6
-
104
-
-
77953691004
-
Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response
-
Shimano, M.; Ouchi, N.; Shibata, R.; Ohashi, K.; Pimentel, D.R.; Murohara, T. and Walsh, K. (2010) Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response. J. Mol. Cell Cardiol., 49, 210-220.
-
(2010)
J. Mol. Cell Cardiol
, vol.49
, pp. 210-220
-
-
Shimano, M.1
Ouchi, N.2
Shibata, R.3
Ohashi, K.4
Pimentel, D.R.5
Murohara, T.6
Walsh, K.7
-
105
-
-
19944369735
-
Adiponectin-mediated modulation of hypertrophic signals in the heart
-
Shibata, R.; Ouchi, N.; Ito, M.; Kihara, S.; Shiojima, I.; Pimentel, D.R.; Kumada, M.; Sato, K.; Schiekofer, S.; Ohashi, K.; Funahashi, T.; Colucci, W.S. and Walsh, K. (2004) Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat. Med., 10, 1384-1389.
-
(2004)
Nat. Med
, vol.10
, pp. 1384-1389
-
-
Shibata, R.1
Ouchi, N.2
Ito, M.3
Kihara, S.4
Shiojima, I.5
Pimentel, D.R.6
Kumada, M.7
Sato, K.8
Schiekofer, S.9
Ohashi, K.10
Funahashi, T.11
Colucci, W.S.12
Walsh, K.13
-
106
-
-
33744976813
-
Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells
-
Hattori, Y.; Suzuki, K.; Hattori, S. and Kasai, K. (2006) Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells. Hypertension, 47, 1183-1188.
-
(2006)
Hypertension
, vol.47
, pp. 1183-1188
-
-
Hattori, Y.1
Suzuki, K.2
Hattori, S.3
Kasai, K.4
-
107
-
-
2942720979
-
Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin
-
Kobayashi, H.; Ouchi, N.; Kihara, S.; Walsh, K.; Kumada, M.; Abe, Y.; Funahashi, T. and Matsuzawa, Y. (2004) Selective suppression of endothelial cell apoptosis by the high molecular weight form of adiponectin. Circ. Res., 94, e27-31.
-
(2004)
Circ. Res
, vol.94
-
-
Kobayashi, H.1
Ouchi, N.2
Kihara, S.3
Walsh, K.4
Kumada, M.5
Abe, Y.6
Funahashi, T.7
Matsuzawa, Y.8
-
108
-
-
0041355355
-
Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells
-
Morrow, V.A.; Foufelle, F.; Connell, J.M.; Petrie, J.R.; Gould, G.W. and Salt, I.P. (2003) Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells. J. Biol. Chem., 278, 31629-31639.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 31629-31639
-
-
Morrow, V.A.1
Foufelle, F.2
Connell, J.M.3
Petrie, J.R.4
Gould, G.W.5
Salt, I.P.6
-
109
-
-
39449096289
-
Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells
-
Xie, Z.; Dong, Y.; Scholz, R.; Neumann, D. and Zou, M.H. (2008) Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells. Circulation, 117, 952-962.
-
(2008)
Circulation
, vol.117
, pp. 952-962
-
-
Xie, Z.1
Dong, Y.2
Scholz, R.3
Neumann, D.4
Zou, M.H.5
-
110
-
-
45549088112
-
Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase
-
Boyle, J.G.; Logan, P.J.; Ewart, M.A.; Reihill, J.A.; Ritchie, S.A.; Connell, J.M.; Cleland, S.J. and Salt, I.P. (2008) Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase. J. Biol. Chem., 283, 11210-11217.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 11210-11217
-
-
Boyle, J.G.1
Logan, P.J.2
Ewart, M.A.3
Reihill, J.A.4
Ritchie, S.A.5
Connell, J.M.6
Cleland, S.J.7
Salt, I.P.8
-
111
-
-
77952885895
-
Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside in the muscle microcirculation increases nitric oxide synthesis and microvascular perfusion
-
Bradley, E.A.; Eringa, E.C.; Stehouwer, C.D.; Korstjens, I.; van Nieuw Amerongen, G.P.; Musters, R.; Sipkema, P.; Clark, M.G. and Rattigan, S. (2010) Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside in the muscle microcirculation increases nitric oxide synthesis and microvascular perfusion. Arterioscler. Thromb. Vasc. Biol., 30, 1137-1142.
-
(2010)
Arterioscler. Thromb. Vasc. Biol
, vol.30
, pp. 1137-1142
-
-
Bradley, E.A.1
Eringa, E.C.2
Stehouwer, C.D.3
Korstjens, I.4
van Nieuw, A.G.P.5
Musters, R.6
Sipkema, P.7
Clark, M.G.8
Rattigan, S.9
-
112
-
-
0141960109
-
AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells
-
Lee, M.; Hwang, J.T.; Lee, H.J.; Jung, S.N.; Kang, I.; Chi, S.G.; Kim, S.S. and Ha, J. (2003) AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells. J. Biol. Chem., 278, 39653-39661.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 39653-39661
-
-
Lee, M.1
Hwang, J.T.2
Lee, H.J.3
Jung, S.N.4
Kang, I.5
Chi, S.G.6
Kim, S.S.7
Ha, J.8
-
113
-
-
33846839339
-
AMPactivated protein kinase mediates VEGF-stimulated endothelial NO production
-
Reihill, J.A.; Ewart, M.A.; Hardie, D.G. and Salt, I.P. (2007) AMPactivated protein kinase mediates VEGF-stimulated endothelial NO production. Biochem. Biophys. Res. Commun., 354, 1084-1088.
-
(2007)
Biochem. Biophys. Res. Commun
, vol.354
, pp. 1084-1088
-
-
Reihill, J.A.1
Ewart, M.A.2
Hardie, D.G.3
Salt, I.P.4
-
114
-
-
3342915617
-
AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation
-
Nagata, D.; Takeda, R.; Sata, M.; Satonaka, H.; Suzuki, E.; Nagano, T. and Hirata, Y. (2004) AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation. Circulation, 110, 444-451.
-
(2004)
Circulation
, vol.110
, pp. 444-451
-
-
Nagata, D.1
Takeda, R.2
Sata, M.3
Satonaka, H.4
Suzuki, E.5
Nagano, T.6
Hirata, Y.7
-
115
-
-
77951251172
-
Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitricoxide synthase
-
Stahmann, N.; Woods, A.; Spengler, K.; Heslegrave, A.; Bauer, R.; Krause, S.; Viollet, B.; Carling, D. and Heller, R. (2010) Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitricoxide synthase. J. Biol. Chem., 285, 10638-10652.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 10638-10652
-
-
Stahmann, N.1
Woods, A.2
Spengler, K.3
Heslegrave, A.4
Bauer, R.5
Krause, S.6
Viollet, B.7
Carling, D.8
Heller, R.9
-
116
-
-
68349086952
-
Pravastatin accelerates ischemia-induced angiogenesis through AMP-activated protein kinase
-
Izumi, Y.; Shiota, M.; Kusakabe, H.; Hikita, Y.; Nakao, T.; Nakamura, Y.; Muro, T.; Miura, K.; Yoshiyama, M. and Iwao, H. (2009) Pravastatin accelerates ischemia-induced angiogenesis through AMP-activated protein kinase. Hypertens. Res., 32, 675-679.
-
(2009)
Hypertens. Res
, vol.32
, pp. 675-679
-
-
Izumi, Y.1
Shiota, M.2
Kusakabe, H.3
Hikita, Y.4
Nakao, T.5
Nakamura, Y.6
Muro, T.7
Miura, K.8
Yoshiyama, M.9
Iwao, H.10
-
117
-
-
77953226963
-
Activation of AMP-activated protein kinase inhibits oxidized LDL-triggered endoplasmic reticulum stress in vivo
-
Dong, Y.; Zhang, M.; Wang, S.; Liang, B.; Zhao, Z.; Liu, C.; Wu, M.; Choi, H.C.; Lyons, T.J. and Zou, M.H. (2010) Activation of AMP-activated protein kinase inhibits oxidized LDL-triggered endoplasmic reticulum stress in vivo. Diabetes, 59, 1386-1396.
-
(2010)
Diabetes
, vol.59
, pp. 1386-1396
-
-
Dong, Y.1
Zhang, M.2
Wang, S.3
Liang, B.4
Zhao, Z.5
Liu, C.6
Wu, M.7
Choi, H.C.8
Lyons, T.J.9
Zou, M.H.10
-
118
-
-
71749087771
-
Activation of AMPactivated protein kinase suppresses oxidized low-density lipoprotein-induced macrophage proliferation
-
Ishii, N.; Matsumura, T.; Kinoshita, H.; Motoshima, H.; Kojima, K.; Tsutsumi, A.; Kawasaki, S.; Yano, M.; Senokuchi, T.; Asano, T.; Nishikawa, T. and Araki, E. (2009) Activation of AMPactivated protein kinase suppresses oxidized low-density lipoprotein-induced macrophage proliferation. J. Biol. Chem., 284, 34561-34569.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 34561-34569
-
-
Ishii, N.1
Matsumura, T.2
Kinoshita, H.3
Motoshima, H.4
Kojima, K.5
Tsutsumi, A.6
Kawasaki, S.7
Yano, M.8
Senokuchi, T.9
Asano, T.10
Nishikawa, T.11
Araki, E.12
-
119
-
-
77149134285
-
Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo
-
Dong, Y.; Zhang, M.; Liang, B.; Xie, Z.; Zhao, Z.; Asfa, S.; Choi, H.C. and Zou, M.H. (2010) Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo. Circulation, 121, 792-803.
-
(2010)
Circulation
, vol.121
, pp. 792-803
-
-
Dong, Y.1
Zhang, M.2
Liang, B.3
Xie, Z.4
Zhao, Z.5
Asfa, S.6
Choi, H.C.7
Zou, M.H.8
-
120
-
-
77951167843
-
Mechanism and role of high density lipoprotein-induced activation of AMP-activated protein kinase in endothelial cells
-
Kimura, T.; Tomura, H.; Sato, K.; Ito, M.; Matsuoka, I.; Im, D.S.; Kuwabara, A.; Mogi, C.; Itoh, H.; Kurose, H.; Murakami, M. and Okajima, F. (2010) Mechanism and role of high density lipoprotein-induced activation of AMP-activated protein kinase in endothelial cells. J. Biol. Chem., 285, 4387-4397.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 4387-4397
-
-
Kimura, T.1
Tomura, H.2
Sato, K.3
Ito, M.4
Matsuoka, I.5
Im, D.S.6
Kuwabara, A.7
Mogi, C.8
Itoh, H.9
Kurose, H.10
Murakami, M.11
Okajima, F.12
-
121
-
-
77949275143
-
Targeting of renal proximal tubule Na,K-ATPase by salt-inducible kinase
-
Taub, M.; Springate, J.E. and Cutuli, F. (2010) Targeting of renal proximal tubule Na,K-ATPase by salt-inducible kinase. Biochem. Biophys. Res. Commun., 393, 339-344.
-
(2010)
Biochem. Biophys. Res. Commun
, vol.393
, pp. 339-344
-
-
Taub, M.1
Springate, J.E.2
Cutuli, F.3
-
122
-
-
14044254863
-
Regulation of the energy sensor AMP-activated protein kinase in the kidney by dietary salt intake and osmolality
-
Fraser, S.; Mount, P.; Hill, R.; Levidiotis, V.; Katsis, F.; Stapleton, D.; Kemp, B.E. and Power, D.A. (2005) Regulation of the energy sensor AMP-activated protein kinase in the kidney by dietary salt intake and osmolality. Am. J. Physiol. Renal. Physiol., 288, F578-586.
-
(2005)
Am. J. Physiol. Renal. Physiol
, vol.288
-
-
Fraser, S.1
Mount, P.2
Hill, R.3
Levidiotis, V.4
Katsis, F.5
Stapleton, D.6
Kemp, B.E.7
Power, D.A.8
-
124
-
-
77954328796
-
Potential health benefits of Indian spices in the symptoms of the metabolic syndrome: A review
-
Iyer, A.; Panchal, S.; Poudyal, H. and Brown, L. (2009) Potential health benefits of Indian spices in the symptoms of the metabolic syndrome: a review. Indian J. Biochem. Biophys., 46, 467-481.
-
(2009)
Indian J. Biochem. Biophys
, vol.46
, pp. 467-481
-
-
Iyer, A.1
Panchal, S.2
Poudyal, H.3
Brown, L.4
-
125
-
-
70350560556
-
Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMP-activated protein kinase in the heart
-
Ko, H.J.; Zhang, Z.; Jung, D.Y.; Jun, J.Y.; Ma, Z.; Jones, K.E.; Chan, S.Y. and Kim, J.K. (2009) Nutrient stress activates inflammation and reduces glucose metabolism by suppressing AMP-activated protein kinase in the heart. Diabetes, 58, 2536-2546.
-
(2009)
Diabetes
, vol.58
, pp. 2536-2546
-
-
Ko, H.J.1
Zhang, Z.2
Jung, D.Y.3
Jun, J.Y.4
Ma, Z.5
Jones, K.E.6
Chan, S.Y.7
Kim, J.K.8
-
126
-
-
77956695619
-
5-aminoimidazole-4-carboxamide ribonucleoside and AMP-activated protein kinase inhibit signalling through NF-kappaB
-
Katerelos, M.; Mudge, S.J.; Stapleton, D.; Auwardt, R.B.; Fraser, S.A.; Chen, C.G.; Kemp, B.E. and Power, D.A. (2010) 5- aminoimidazole-4-carboxamide ribonucleoside and AMP-activated protein kinase inhibit signalling through NF-kappaB. Immunol. Cell Biol., 88, 754-760.
-
(2010)
Immunol. Cell Biol
, vol.88
, pp. 754-760
-
-
Katerelos, M.1
Mudge, S.J.2
Stapleton, D.3
Auwardt, R.B.4
Fraser, S.A.5
Chen, C.G.6
Kemp, B.E.7
Power, D.A.8
-
127
-
-
70349633673
-
Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin
-
Li, X.N.; Song, J.; Zhang, L.; LeMaire, S.A.; Hou, X.; Zhang, C.; Coselli, J.S.; Chen, L.; Wang, X.L.; Zhang, Y. and Shen, Y.H. (2009) Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin. Diabetes, 58, 2246-2257.
-
(2009)
Diabetes
, vol.58
, pp. 2246-2257
-
-
Li, X.N.1
Song, J.2
Zhang, L.3
Lemaire, S.A.4
Hou, X.5
Zhang, C.6
Coselli, J.S.7
Chen, L.8
Wang, X.L.9
Zhang, Y.10
Shen, Y.H.11
-
128
-
-
77952741468
-
Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway
-
Hou, X.; Song, J.; Li, X.N.; Zhang, L.; Wang, X.; Chen, L. and Shen, Y.H. (2010) Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway. Biochem. Biophys. Res. Commun., 396, 199-205.
-
(2010)
Biochem. Biophys. Res. Commun
, vol.396
, pp. 199-205
-
-
Hou, X.1
Song, J.2
Li, X.N.3
Zhang, L.4
Wang, X.5
Chen, L.6
Shen, Y.H.7
-
129
-
-
80052058373
-
Fenofibrate suppresses microvascular inflammation and apoptosis through adenosine monophosphate-activated protein kinase activation
-
Epub ahead of print
-
Tomizawa, A.; Hattori, Y.; Inoue, T.; Hattori, S. and Kasai, K. (2010) Fenofibrate suppresses microvascular inflammation and apoptosis through adenosine monophosphate-activated protein kinase activation. Metabolism, [Epub ahead of print].
-
(2010)
Metabolism
-
-
Tomizawa, A.1
Hattori, Y.2
Inoue, T.3
Hattori, S.4
Kasai, K.5
-
130
-
-
67549131188
-
Energy homeostasis and cancer prevention: The AMP-activated protein kinase
-
Fay, J.R.; Steele, V. and Crowell, J.A. (2009) Energy homeostasis and cancer prevention: the AMP-activated protein kinase. Cancer Prev. Res., (Phila Pa), 2, 301-309.
-
(2009)
Cancer Prev. Res., (Phila Pa)
, vol.2
, pp. 301-309
-
-
Fay, J.R.1
Steele, V.2
Crowell, J.A.3
-
131
-
-
69549097703
-
New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
-
Libby, G.; Donnelly, L.A.; Donnan, P.T.; Alessi, D.R.; Morris, A.D. and Evans, J.M. (2009) New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes. Diabetes Care, 32, 1620-1625.
-
(2009)
Diabetes Care
, vol.32
, pp. 1620-1625
-
-
Libby, G.1
Donnelly, L.A.2
Donnan, P.T.3
Alessi, D.R.4
Morris, A.D.5
Evans, J.M.6
-
132
-
-
70449584566
-
AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply
-
Hoppe, S.; Bierhoff, H.; Cado, I.; Weber, A.; Tiebe, M.; Grummt, I. and Voit, R. (2009) AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply. Proc. Natl. Acad. Sci. USA, 106, 17781-17786.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 17781-17786
-
-
Hoppe, S.1
Bierhoff, H.2
Cado, I.3
Weber, A.4
Tiebe, M.5
Grummt, I.6
Voit, R.7
-
133
-
-
33751552452
-
Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP kinase signaling
-
Steinberg, G.R.; Michell, B.J.; van Denderen, B.J.; Watt, M.J.; Carey, A.L.; Fam, B.C.; Andrikopoulos, S.; Proietto, J.; Gorgun, C.Z.; Carling, D.; Hotamisligil, G.S.; Febbraio, M.A.; Kay, T.W. and Kemp, B.E. (2006) Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP kinase signaling. Cell Metab., 4, 465-474.
-
(2006)
Cell Metab
, vol.4
, pp. 465-474
-
-
Steinberg, G.R.1
Michell, B.J.2
van Denderen, B.J.3
Watt, M.J.4
Carey, A.L.5
Fam, B.C.6
Andrikopoulos, S.7
Proietto, J.8
Gorgun, C.Z.9
Carling, D.10
Hotamisligil, G.S.11
Febbraio, M.A.12
Kay, T.W.13
Kemp, B.E.14
-
134
-
-
70449707334
-
AMP-activated protein kinase confers protection against TNF-{alpha}-induced cardiac cell death
-
Kewalramani, G.; Puthanveetil, P.; Wang, F.; Kim, M.S.; Deppe, S.; Abrahani, A.; Luciani, D.S.; Johnson, J.D. and Rodrigues, B. (2009) AMP-activated protein kinase confers protection against TNF-{alpha}-induced cardiac cell death. Cardiovasc. Res., 84, 42-53.
-
(2009)
Cardiovasc. Res
, vol.84
, pp. 42-53
-
-
Kewalramani, G.1
Puthanveetil, P.2
Wang, F.3
Kim, M.S.4
Deppe, S.5
Abrahani, A.6
Luciani, D.S.7
Johnson, J.D.8
Rodrigues, B.9
-
135
-
-
33744537874
-
Metformin prevents alcohol-induced liver injury in the mouse: Critical role of plasminogen activator inhibitor-1
-
Bergheim, I.; Guo, L.; Davis, M.A.; Lambert, J.C.; Beier, J.I.; Duveau, I.; Luyendyk, J.P.; Roth, R.A. and Arteel, G.E. (2006) Metformin prevents alcohol-induced liver injury in the mouse: Critical role of plasminogen activator inhibitor-1. Gastroenterology, 130, 2099-2112.
-
(2006)
Gastroenterology
, vol.130
, pp. 2099-2112
-
-
Bergheim, I.1
Guo, L.2
Davis, M.A.3
Lambert, J.C.4
Beier, J.I.5
Duveau, I.6
Luyendyk, J.P.7
Roth, R.A.8
Arteel, G.E.9
-
136
-
-
70349260288
-
Fenofibrate differentially regulates plasminogen activator inhibitor- 1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner
-
Chanda, D.; Lee, C.H.; Kim, Y.H.; Noh, J.R.; Kim, D.K.; Park, J.H.; Hwang, J.H.; Lee, M.R.; Jeong, K.H.; Lee, I.K.; Kweon, G.R.; Shong, M.; Oh, G.T.; Chiang, J.Y. and Choi, H.S. (2009) Fenofibrate differentially regulates plasminogen activator inhibitor- 1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner. Hepatology, 50, 880-892.
-
(2009)
Hepatology
, vol.50
, pp. 880-892
-
-
Chanda, D.1
Lee, C.H.2
Kim, Y.H.3
Noh, J.R.4
Kim, D.K.5
Park, J.H.6
Hwang, J.H.7
Lee, M.R.8
Jeong, K.H.9
Lee, I.K.10
Kweon, G.R.11
Shong, M.12
Oh, G.T.13
Chiang, J.Y.14
Choi, H.S.15
-
137
-
-
65349138878
-
Regulation of erythrocyte survival by AMP-activated protein kinase
-
Foller, M.; Sopjani, M.; Koka, S.; Gu, S.; Mahmud, H.; Wang, K.; Floride, E.; Schleicher, E.; Schulz, E.; Munzel, T. and Lang, F. (2009) Regulation of erythrocyte survival by AMP-activated protein kinase. FASEB J., 23, 1072-1080.
-
(2009)
FASEB J
, vol.23
, pp. 1072-1080
-
-
Foller, M.1
Sopjani, M.2
Koka, S.3
Gu, S.4
Mahmud, H.5
Wang, K.6
Floride, E.7
Schleicher, E.8
Schulz, E.9
Munzel, T.10
Lang, F.11
-
138
-
-
63849210402
-
The regulation and function of mammalian AMPK-related kinases
-
Bright, N.J.; Thornton, C. and Carling, D. (2009) The regulation and function of mammalian AMPK-related kinases. Acta Physiol. (Oxf)., 196, 15-26.
-
(2009)
Acta Physiol. (Oxf)
, vol.196
, pp. 15-26
-
-
Bright, N.J.1
Thornton, C.2
Carling, D.3
-
139
-
-
73549091714
-
Blocking the salt-inducible kinase 1 network prevents the increases in cell sodium transport caused by a hypertension-linked mutation in human alpha-adducin
-
Stenstrom, K.; Takemori, H.; Bianchi, G.; Katz, A.I. and Bertorello, A.M. (2009) Blocking the salt-inducible kinase 1 network prevents the increases in cell sodium transport caused by a hypertension-linked mutation in human alpha-adducin. J. Hypertens., 27, 2452-2457.
-
(2009)
J. Hypertens
, vol.27
, pp. 2452-2457
-
-
Stenstrom, K.1
Takemori, H.2
Bianchi, G.3
Katz, A.I.4
Bertorello, A.M.5
-
140
-
-
75949097288
-
The regulation of AMPK signaling in a natural state of profound metabolic rate depression
-
Ramnanan, C.J.; McMullen, D.C.; Groom, A.G. and Storey, K.B. (2010) The regulation of AMPK signaling in a natural state of profound metabolic rate depression. Mol. Cell Biochem., 335, 91-105.
-
(2010)
Mol. Cell Biochem
, vol.335
, pp. 91-105
-
-
Ramnanan, C.J.1
McMullen, D.C.2
Groom, A.G.3
Storey, K.B.4
-
141
-
-
72549083582
-
Exercise-induced histone modifications in human skeletal muscle
-
McGee, S.L.; Fairlie, E.; Garnham, A.P. and Hargreaves, M. (2009) Exercise-induced histone modifications in human skeletal muscle. J. Physiol., 587, 5951-5958.
-
(2009)
J. Physiol
, vol.587
, pp. 5951-5958
-
-
McGee, S.L.1
Fairlie, E.2
Garnham, A.P.3
Hargreaves, M.4
-
142
-
-
77649311383
-
Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
-
Onken, B. and Driscoll, M. (2010) Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1. PLoS One, 5, e8758.
-
(2010)
PLoS One
, vol.5
-
-
Onken, B.1
Driscoll, M.2
-
143
-
-
77953916891
-
Differences in AMPK expression between subcutaneous and visceral adipose tissue in morbid obesity
-
Martínez-Agustin, O.; Hernández-Morante, J.J.; Martínez-Plata, E.; Sánchez de Medina, F. and Garaulet, M. (2010) Differences in AMPK expression between subcutaneous and visceral adipose tissue in morbid obesity. Regul. Pept., 163, 31-36.
-
(2010)
Regul. Pept
, vol.163
, pp. 31-36
-
-
Martínez-Agustin, O.1
Hernández-Morante, J.J.2
Martínez-Plata, E.3
de Medina, S.F.4
Garaulet, M.5
-
144
-
-
4344639035
-
Molecular genetics: The Emperor's clothes of drug discovery?
-
Higgs, G. (2004) Molecular genetics: the Emperor's clothes of drug discovery? Drug Discov. Today, 9, 727-729.
-
(2004)
Drug Discov. Today
, vol.9
, pp. 727-729
-
-
Higgs, G.1
-
145
-
-
67650914230
-
AMPK in Health and Disease
-
Steinberg, G.R. and Kemp, B.E. (2009) AMPK in Health and Disease. Physiol. Rev., 89, 1025-1078.
-
(2009)
Physiol. Rev
, vol.89
, pp. 1025-1078
-
-
Steinberg, G.R.1
Kemp, B.E.2
-
146
-
-
73449087698
-
AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase
-
Benziane, B.; Bjornholm, M.; Lantier, L.; Viollet, B.; Zierath, J.R. and Chibalin, A.V. (2009) AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase. Am. J. Physiol. Cell Physiol., 297, C1554-1566.
-
(2009)
Am. J. Physiol. Cell Physiol
, vol.297
-
-
Benziane, B.1
Bjornholm, M.2
Lantier, L.3
Viollet, B.4
Zierath, J.R.5
Chibalin, A.V.6
-
147
-
-
78650270601
-
Ajoene, A Stable Garlic By-Product, Inhibits High Fat Diet-Induced Hepatic Steatosis and Oxidative Injury Through LKB1-Dependent AMPK Activation
-
Han, C.Y. (2011) Ajoene, A Stable Garlic By-Product, Inhibits High Fat Diet-Induced Hepatic Steatosis and Oxidative Injury Through LKB1-Dependent AMPK Activation. Antioxid. Redox Signal., 14, 187-202.
-
(2011)
Antioxid. Redox Signal
, vol.14
, pp. 187-202
-
-
Han, C.Y.1
-
148
-
-
78650917844
-
Corrigendum to The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways
-
Ahn, J.; Lee, H.; Kim, S.; Park, J. and Ha, T. (2011) Corrigendum to The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways. Biochem. Biophys. Res. Commun., 404, 579-579.
-
(2011)
Biochem. Biophys. Res. Commun
, vol.404
, pp. 579-579
-
-
Ahn, J.1
Lee, H.2
Kim, S.3
Park, J.4
Ha, T.5
-
149
-
-
69249216362
-
Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells
-
Kim, T.; Davis, J.; Zhang, A.J.; He, X. and Mathews, S.T. (2009) Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells. Biochem. Biophys. Res. Commun., 388, 377-382.
-
(2009)
Biochem. Biophys. Res. Commun
, vol.388
, pp. 377-382
-
-
Kim, T.1
Davis, J.2
Zhang, A.J.3
He, X.4
Mathews, S.T.5
-
150
-
-
78651450568
-
Caffeine activates preferentially α1-isoform of 5'AMP-activated protein kinase in rat skeletal muscle
-
Egawa, T.; Hamada, T.; Ma, X.; Karaike, K.; Kameda, N.; Masuda, S.; Iwanaka, N. and Hayashi, T. (2011) Caffeine activates preferentially α1-isoform of 5'AMP-activated protein kinase in rat skeletal muscle. Acta. Physiologica., 201, 227-238.
-
(2011)
Acta. Physiologica
, vol.201
, pp. 227-238
-
-
Egawa, T.1
Hamada, T.2
Ma, X.3
Karaike, K.4
Kameda, N.5
Masuda, S.6
Iwanaka, N.7
Hayashi, T.8
-
151
-
-
70449552861
-
Insulin resistance is a cellular antioxidant defense mechanism
-
Hoehn, K.L.; Salmon, A.B.; Hohnen-Behrens, C.; Turner, N.; Hoy, A.J.; Maghzal, G.J.; Stocker, R.; Van Remmen, H.; Kraegen, E.W.; Cooney, G.J.; Richardson, A.R. and James, D.E. (2009) Insulin resistance is a cellular antioxidant defense mechanism. Proc. Natl. Acad. Sci. USA, 106, 17787-17792.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 17787-17792
-
-
Hoehn, K.L.1
Salmon, A.B.2
Hohnen-Behrens, C.3
Turner, N.4
Hoy, A.J.5
Maghzal, G.J.6
Stocker, R.7
van Remmen, H.8
Kraegen, E.W.9
Cooney, G.J.10
Richardson, A.R.11
James, D.E.12
-
152
-
-
77951486280
-
Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate-, high fat-fed rats
-
Poudyal, H.; Campbell, F. and Brown, L. (2010) Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate-, high fat-fed rats. J. Nutr., 140, 946-953.
-
(2010)
J. Nutr
, vol.140
, pp. 946-953
-
-
Poudyal, H.1
Campbell, F.2
Brown, L.3
-
153
-
-
78149477179
-
Comparison of purple carrot juice and beta-carotene in a high-carbohydrate, highfat diet-fed rat model of the metabolic syndrome
-
Poudyal, H.; Panchal, S. and Brown, L. (2010) Comparison of purple carrot juice and beta-carotene in a high-carbohydrate, highfat diet-fed rat model of the metabolic syndrome. Br. J. Nutr., 104, 1322-1332.
-
(2010)
Br. J. Nutr
, vol.104
, pp. 1322-1332
-
-
Poudyal, H.1
Panchal, S.2
Brown, L.3
-
154
-
-
77954984111
-
Antidiabetic effect of Dodonaea viscosa aerial parts in high fat diet and low dose streptozotocininduced type 2 diabetic rats: A mechanistic approach
-
Veerapur, V.P.; Prabhakar, K.R.; Kandadi, M.R.; Srinivasan, K.K. and Unnikrishnan, M.K. (2010) Antidiabetic effect of Dodonaea viscosa aerial parts in high fat diet and low dose streptozotocininduced type 2 diabetic rats: A mechanistic approach. Pharm. Biol., 48, 1137-1148.
-
(2010)
Pharm. Biol
, vol.48
, pp. 1137-1148
-
-
Veerapur, V.P.1
Prabhakar, K.R.2
Kandadi, M.R.3
Srinivasan, K.K.4
Unnikrishnan, M.K.5
-
155
-
-
0031007065
-
The AMP-activated protein kinase--fuel gauge of the mammalian cell
-
Hardie, D.G. and Carling, D. (1997) The AMP-activated protein kinase--fuel gauge of the mammalian cell? Eur. J. Biochem., 246, 259-273.
-
(1997)
Eur. J. Biochem
, vol.246
, pp. 259-273
-
-
Hardie, D.G.1
Carling, D.2
-
156
-
-
0032792665
-
AMP-activated protein kinase, a metabolic master switch: Possible roles in type 2 diabetes
-
Winder, W.W. and Hardie, D.G. (1999) AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes. Am. J. Physiol., 277, E1-10.
-
(1999)
Am. J. Physiol
, vol.277
-
-
Winder, W.W.1
Hardie, D.G.2
-
157
-
-
0034306362
-
Isoform-specific and exercise intensity-dependent activation of 5'-AMP-activated protein kinase in human skeletal muscle
-
Wojtaszewski, J.F.; Nielsen, P.; Hansen, B.F.; Richter, E.A. and Kiens, B. (2000) Isoform-specific and exercise intensity-dependent activation of 5'-AMP-activated protein kinase in human skeletal muscle. J. Physiol., 528 Pt 1, 221-226.
-
(2000)
J. Physiol
, vol.528
, Issue.Pt 1
, pp. 221-226
-
-
Wojtaszewski, J.F.1
Nielsen, P.2
Hansen, B.F.3
Richter, E.A.4
Kiens, B.5
-
158
-
-
0037122766
-
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
-
Minokoshi, Y.; Kim, Y.B.; Peroni, O.D.; Fryer, L.G.; Muller, C.; Carling, D. and Kahn, B.B. (2002) Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature, 415, 339-343.
-
(2002)
Nature
, vol.415
, pp. 339-343
-
-
Minokoshi, Y.1
Kim, Y.B.2
Peroni, O.D.3
Fryer, L.G.4
Muller, C.5
Carling, D.6
Kahn, B.B.7
-
159
-
-
10744230065
-
LKB1 is the upstream kinase in the AMPactivated protein kinase cascade
-
Woods, A.; Johnstone, S.R.; Dickerson, K.; Leiper, F.C.; Fryer, L.G.; Neumann, D.; Schlattner, U.; Wallimann, T.; Carlson, M. and Carling, D. (2003) LKB1 is the upstream kinase in the AMPactivated protein kinase cascade. Curr. Biol., 13, 2004-2008.
-
(2003)
Curr. Biol
, vol.13
, pp. 2004-2008
-
-
Woods, A.1
Johnstone, S.R.2
Dickerson, K.3
Leiper, F.C.4
Fryer, L.G.5
Neumann, D.6
Schlattner, U.7
Wallimann, T.8
Carlson, M.9
Carling, D.10
-
160
-
-
0347318052
-
The AMP-activated protein kinase cascade-- a unifying system for energy control
-
Carling, D. (2004) The AMP-activated protein kinase cascade-- a unifying system for energy control. Trends Biochem. Sci., 29, 18-24.
-
(2004)
Trends Biochem. Sci
, vol.29
, pp. 18-24
-
-
Carling, D.1
-
161
-
-
23044432463
-
Calmodulindependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
-
Hawley, S.A.; Pan, D.A.; Mustard, K.J.; Ross, L.; Bain, J.; Edelman, A.M.; Frenguelli, B.G. and Hardie, D.G. (2005) Calmodulindependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab., 2, 9-19.
-
(2005)
Cell Metab
, vol.2
, pp. 9-19
-
-
Hawley, S.A.1
Pan, D.A.2
Mustard, K.J.3
Ross, L.4
Bain, J.5
Edelman, A.M.6
Frenguelli, B.G.7
Hardie, D.G.8
-
162
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur, J.A.; Pearson, K.J.; Price, N.L.; Jamieson, H.A.; Lerin, C.; Kalra, A.; Prabhu, V.V.; Allard, J.S.; Lopez-Lluch, G.; Lewis, K.; Pistell, P.J.; Poosala, S.; Becker, K.G.; Boss, O.; Gwinn, D.; Wang, M.; Ramaswamy, S.; Fishbein, K.W.; Spencer, R.G.; Lakatta, E.G.; Le Couteur, D.; Shaw, R.J.; Navas, P.; Puigserver, P.; Ingram, D.K.; de Cabo, R. and Sinclair, D.A. (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature, 444, 337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
de Cabo, R.26
Sinclair, D.A.27
more..
-
163
-
-
58149339613
-
Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
-
Narbonne, P. and Roy, R. (2009) Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature, 457, 210-214.
-
(2009)
Nature
, vol.457
, pp. 210-214
-
-
Narbonne, P.1
Roy, R.2
|