메뉴 건너뛰기




Volumn 88, Issue 7, 2010, Pages 754-760

5-aminoimidazole-4-carboxamide ribonucleoside and AMP-activated protein kinase inhibit signalling through NF-B

Author keywords

AICAR; AMP activated protein kinase; BAEC; NF B

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHOTREXATE; OLIGONUCLEOTIDE; SALAZOSULFAPYRIDINE;

EID: 77956695619     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2010.44     Document Type: Article
Times cited : (49)

References (41)
  • 1
    • 0031007065 scopus 로고    scopus 로고
    • The AMP-activated protein kinase-fuel gauge of the mammalian cell?
    • Hardie DG, Carling D. The AMP-activated protein kinase-fuel gauge of the mammalian cell? Eur J Biochem 1997; 246: 259-273.
    • (1997) Eur J Biochem , vol.246 , pp. 259-273
    • Hardie, D.G.1    Carling, D.2
  • 3
    • 67651236115 scopus 로고    scopus 로고
    • Role of the AMP-activated protein kinase in regulating fatty acid metabolism during exercise
    • Steinberg GR. Role of the AMP-activated protein kinase in regulating fatty acid metabolism during exercise. Appl Physiol Nutr Metab 2009; 34: 315-322.
    • (2009) Appl Physiol Nutr Metab , vol.34 , pp. 315-322
    • Steinberg, G.R.1
  • 4
    • 85047689953 scopus 로고
    • 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?
    • Corton JM, Gillespie JG, Hawley SA, Hardie DG. 5-aminoimidazole-4- carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? Eur J Biochem 1995; 229: 558-565.
    • (1995) Eur J Biochem , vol.229 , pp. 558-565
    • Corton, J.M.1    Gillespie, J.G.2    Hawley, S.A.3    Hardie, D.G.4
  • 5
    • 0033664017 scopus 로고    scopus 로고
    • Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase
    • Fryer LG, Hajduch E, Rencurel F, Salt IP, Hundal HS, Hardie DG et al. Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase. Diabetes 2000; 49: 1978-1985.
    • (2000) Diabetes , vol.49 , pp. 1978-1985
    • Fryer, L.G.1    Hajduch, E.2    Rencurel, F.3    Salt, I.P.4    Hundal, H.S.5    Hardie, D.G.6
  • 6
    • 0029978799 scopus 로고    scopus 로고
    • Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise
    • Winder WW, Hardie DG. Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am J Physiol 1996; 270: E299-E304.
    • (1996) Am J Physiol , vol.270
    • Winder, W.W.1    Hardie, D.G.2
  • 7
    • 26844574330 scopus 로고    scopus 로고
    • Acute renal ischemia rapidly activates the energy sensor AMPK but does not increase phosphorylation of eNOS-Ser1177
    • Mount PF, Hill RE, Fraser SA, Levidiotis V, Katsis F, Kemp BE et al. Acute renal ischemia rapidly activates the energy sensor AMPK but does not increase phosphorylation of eNOS-Ser1177. Am J Physiol Renal Physiol 2005; 289: F1103-F1115.
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Mount, P.F.1    Hill, R.E.2    Fraser, S.A.3    Levidiotis, V.4    Katsis, F.5    Kemp, B.E.6
  • 8
    • 66149088886 scopus 로고    scopus 로고
    • Activation of AMPK inhibits inflammation in MRL/lpr mouse mesangial cells
    • Peairs A, Radjavi A, Davis S, Li L, Ahmed A, Giri S et al. Activation of AMPK inhibits inflammation in MRL/lpr mouse mesangial cells. Clin Exp Immunol 2009; 156: 542-551.
    • (2009) Clin Exp Immunol , vol.156 , pp. 542-551
    • Peairs, A.1    Radjavi, A.2    Davis, S.3    Li, L.4    Ahmed, A.5    Giri, S.6
  • 9
    • 1642499162 scopus 로고    scopus 로고
    • 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: A possible role of AMP-activated protein kinase
    • Giri S, Nath N, Smith B, Viollet B, Singh AK, Singh I. 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase. J Neurosci 2004; 24: 479-487.
    • (2004) J Neurosci , vol.24 , pp. 479-487
    • Giri, S.1    Nath, N.2    Smith, B.3    Viollet, B.4    Singh, A.K.5    Singh, I.6
  • 10
    • 0024475227 scopus 로고
    • NF-kappa B: A pleiotropic mediator of inducible and tissuespecific gene control
    • Lenardo MJ, Baltimore D. NF-kappa B: a pleiotropic mediator of inducible and tissuespecific gene control. Cell 1989; 58: 227-229.
    • (1989) Cell , vol.58 , pp. 227-229
    • Lenardo, M.J.1    Baltimore, D.2
  • 12
  • 13
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of i kappa B synthesis
    • Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 1995; 270: 286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    Didonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 14
    • 0027146488 scopus 로고
    • Pyrrolidine dithiocarbamate inhibits NF-kappa B mobilization and TNF production in human monocytes
    • Ziegler-Heitbrock HW, Sternsdorf T, Liese J, Belohradsky B, Weber C, Wedel A et al. Pyrrolidine dithiocarbamate inhibits NF-kappa B mobilization and TNF production in human monocytes. J Immunol 1993; 151: 6986-6993.
    • (1993) J Immunol , vol.151 , pp. 6986-6993
    • Ziegler-Heitbrock, H.W.1    Sternsdorf, T.2    Liese, J.3    Belohradsky, B.4    Weber, C.5    Wedel, A.6
  • 15
    • 85047676330 scopus 로고
    • Acadesine: The prototype adenosine regulating agent for reducing myocardial ischaemic injury
    • Mullane K. Acadesine: the prototype adenosine regulating agent for reducing myocardial ischaemic injury. Cardiovasc Res 1993; 27: 43-47.
    • (1993) Cardiovasc Res , vol.27 , pp. 43-47
    • Mullane, K.1
  • 16
    • 0028214145 scopus 로고
    • Harnessing nature's own cardiac defense mechanism with acadesine, an adenosine regulating agent: Importance of the endothelium
    • Engler RL. Harnessing nature's own cardiac defense mechanism with acadesine, an adenosine regulating agent: importance of the endothelium. J Card Surg 1994; 9: 482-492.
    • (1994) J Card Surg , vol.9 , pp. 482-492
    • Engler, R.L.1
  • 17
    • 0028167846 scopus 로고
    • Inhibition of NF-kappa B by sodium salicylate and aspirin
    • Kopp E, Ghosh S. Inhibition of NF-kappa B by sodium salicylate and aspirin. Science 1994; 265: 956-959.
    • (1994) Science , vol.265 , pp. 956-959
    • Kopp, E.1    Ghosh, S.2
  • 18
    • 0034670031 scopus 로고    scopus 로고
    • Leflunomide suppresses TNF-induced cellular responses: Effects on NF-kappa B, activator protein-1, c-Jun N-terminal protein kinase, and apoptosis
    • Manna SK, Mukhopadhyay A, Aggarwal BB. Leflunomide suppresses TNF-induced cellular responses: effects on NF-kappa B, activator protein-1, c-Jun N-terminal protein kinase, and apoptosis. J Immunol 2000; 165: 5962-5969.
    • (2000) J Immunol , vol.165 , pp. 5962-5969
    • Manna, S.K.1    Mukhopadhyay, A.2    Aggarwal, B.B.3
  • 19
    • 0030022506 scopus 로고    scopus 로고
    • Expression of NF-kappa B and i kappa B-alpha by aortic endothelium in an arterial injury model
    • Lindner V, Collins T. Expression of NF-kappa B and I kappa B-alpha by aortic endothelium in an arterial injury model. Am J Pathol 1996; 148: 427-438.
    • (1996) Am J Pathol , vol.148 , pp. 427-438
    • Lindner, V.1    Collins, T.2
  • 20
    • 0031721232 scopus 로고    scopus 로고
    • Regulation of nuclear factor kappaB by corticosteroids in rat mesangial cells
    • Auwardt RB, Mudge SJ, Chen CG, Power DA. Regulation of nuclear factor kappaB by corticosteroids in rat mesangial cells. J Am Soc Nephrol 1998; 9: 1620-1628.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1620-1628
    • Auwardt, R.B.1    Mudge, S.J.2    Chen, C.G.3    Power, D.A.4
  • 21
    • 35548999608 scopus 로고    scopus 로고
    • AICAR induces phosphorylation of AMPK in an ATMdependent, LKB1-independent manner
    • Sun Y, Connors KE, Yang DQ. AICAR induces phosphorylation of AMPK in an ATMdependent, LKB1-independent manner. Mol Cell Biochem 2007; 306: 239-245.
    • (2007) Mol Cell Biochem , vol.306 , pp. 239-245
    • Sun, Y.1    Connors, K.E.2    Yang, D.Q.3
  • 22
    • 0030729507 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate inhibits cytokine-induced VCAM-1 gene expression in rat cardiac myocytes
    • Hattori Y, Akimoto K, Murakami Y, Kasai K. Pyrrolidine dithiocarbamate inhibits cytokine-induced VCAM-1 gene expression in rat cardiac myocytes. Mol Cell Biochem 1997; 177: 177-181.
    • (1997) Mol Cell Biochem , vol.177 , pp. 177-181
    • Hattori, Y.1    Akimoto, K.2    Murakami, Y.3    Kasai, K.4
  • 23
    • 0028879819 scopus 로고
    • Role of transcriptional activation of i kappa B alpha in mediation of immunosuppression by glucocorticoids
    • Scheinman RI, Cogswell PC, Lofquist AK, Baldwin Jr AS. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 1995; 270: 283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin Jr., A.S.4
  • 24
    • 33744976813 scopus 로고    scopus 로고
    • Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells
    • Hattori Y, Suzuki K, Hattori S, Kasai K. Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells. Hypertension 2006; 47: 1183-1188.
    • (2006) Hypertension , vol.47 , pp. 1183-1188
    • Hattori, Y.1    Suzuki, K.2    Hattori, S.3    Kasai, K.4
  • 25
    • 57749183407 scopus 로고    scopus 로고
    • Cilostazol inhibits cytokine-induced nuclear factor-kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells
    • Hattori Y, Suzuki K, Tomizawa A, Hirama N, Okayasu T, Hattori S et al. Cilostazol inhibits cytokine-induced nuclear factor-kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells. Cardiovasc Res 2009; 81: 133-139.
    • (2009) Cardiovasc Res , vol.81 , pp. 133-139
    • Hattori, Y.1    Suzuki, K.2    Tomizawa, A.3    Hirama, N.4    Okayasu, T.5    Hattori, S.6
  • 26
    • 28844433635 scopus 로고    scopus 로고
    • The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
    • Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA et al. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 2005; 310: 1642-1646.
    • (2005) Science , vol.310 , pp. 1642-1646
    • Shaw, R.J.1    Lamia, K.A.2    Vasquez, D.3    Koo, S.H.4    Bardeesy, N.5    Depinho, R.A.6
  • 27
    • 8744315928 scopus 로고    scopus 로고
    • Identification of SNF1/AMP kinaserelated kinase as an NF-kappaB-regulated anti-apoptotic kinase involved in CD95-induced motility and invasiveness
    • Legembre P, Schickel R, Barnhart BC, Peter ME. Identification of SNF1/AMP kinaserelated kinase as an NF-kappaB-regulated anti-apoptotic kinase involved in CD95-induced motility and invasiveness. J Biol Chem 2004; 279: 46742-46747.
    • (2004) J Biol Chem , vol.279 , pp. 46742-46747
    • Legembre, P.1    Schickel, R.2    Barnhart, B.C.3    Peter, M.E.4
  • 28
    • 0035871220 scopus 로고    scopus 로고
    • Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK
    • Lefebvre DL, Bai Y, Shahmolky N, Sharma M, Poon R, Drucker DJ et al. Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK. Biochem J 2001; 355: 297-305.
    • (2001) Biochem J , vol.355 , pp. 297-305
    • Lefebvre, D.L.1    Bai, Y.2    Shahmolky, N.3    Sharma, M.4    Poon, R.5    Drucker, D.J.6
  • 29
    • 0029743378 scopus 로고    scopus 로고
    • Effects of adenine nucleotide analogues on myocardial dysfunction during reperfusion after ischemia in dogs
    • Nakai T, Kano S, Satoh K, Hoshi K, Ichihara K. Effects of adenine nucleotide analogues on myocardial dysfunction during reperfusion after ischemia in dogs. J Cardiovasc Pharmacol 1996; 28: 264-270.
    • (1996) J Cardiovasc Pharmacol , vol.28 , pp. 264-270
    • Nakai, T.1    Kano, S.2    Satoh, K.3    Hoshi, K.4    Ichihara, K.5
  • 31
    • 0028032360 scopus 로고
    • Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2)
    • Koong AC, Chen EY, Mivechi NF, Denko NC, Stambrook P, Giaccia AJ. Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2). Cancer Res 1994; 54: 5273-5279.
    • (1994) Cancer Res , vol.54 , pp. 5273-5279
    • Koong, A.C.1    Chen, E.Y.2    Mivechi, N.F.3    Denko, N.C.4    Stambrook, P.5    Giaccia, A.J.6
  • 32
    • 0030991201 scopus 로고    scopus 로고
    • The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism
    • Zhong H, Su Yang H, Erdjument-Bromage H, Tempst P, Ghosh S. The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism. Cell 1997; 89: 413-424.
    • (1997) Cell , vol.89 , pp. 413-424
    • Zhong, H.1    Su Yang, H.2    Erdjument-Bromage, H.3    Tempst, P.4    Ghosh, S.5
  • 33
    • 0032589462 scopus 로고    scopus 로고
    • IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain
    • Sakurai H, Chiba H, Miyoshi H, Sugita T, Toriumi W. IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain. J Biol Chem 1999; 274: 30353-30356.
    • (1999) J Biol Chem , vol.274 , pp. 30353-30356
    • Sakurai, H.1    Chiba, H.2    Miyoshi, H.3    Sugita, T.4    Toriumi, W.5
  • 34
    • 0015541627 scopus 로고
    • Characteristics of cell cultures derived from renal glomeruli
    • Burlington H, Cronkite EP. Characteristics of cell cultures derived from renal glomeruli. Proc Soc Exp Biol Med 1973; 142: 143-149.
    • (1973) Proc Soc Exp Biol Med , vol.142 , pp. 143-149
    • Burlington, H.1    Cronkite, E.P.2
  • 35
    • 0016665070 scopus 로고
    • Culture of arterial endothelial cells: Characterization and growth of bovine aortic cells
    • Booyse FM, Sedlak BJ, Rafelson Jr ME. Culture of arterial endothelial cells: characterization and growth of bovine aortic cells. Thromb Diath Haemorrh 1975; 34: 825-839.
    • (1975) Thromb Diath Haemorrh , vol.34 , pp. 825-839
    • Booyse, F.M.1    Sedlak, B.J.2    Rafelson Jr., M.E.3
  • 36
    • 0029664476 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB activation by a dominant-negative mutant of IkappaBalpha
    • Chen CG, Malliaros J, Katerelos M, d'Apice AJ, Pearse MJ. Inhibition of NF-kappaB activation by a dominant-negative mutant of IkappaBalpha. Mol Immunol 1996; 33: 57-61.
    • (1996) Mol Immunol , vol.33 , pp. 57-61
    • Chen, C.G.1    Malliaros, J.2    Katerelos, M.3    D'Apice, A.J.4    Pearse, M.J.5
  • 38
    • 0029944966 scopus 로고    scopus 로고
    • Regulation of 5¢-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits
    • Dyck JR, Gao G, Widmer J, Stapleton D, Fernandez CS, Kemp BE et al. Regulation of 5¢-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits. J Biol Chem 1996; 271: 17798-17803.
    • (1996) J Biol Chem , vol.271 , pp. 17798-17803
    • Dyck, J.R.1    Gao, G.2    Widmer, J.3    Stapleton, D.4    Fernandez, C.S.5    Kemp, B.E.6
  • 39
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber E, Matthias P, Muller MM, Schaffner W. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 1989; 17: 6419.
    • (1989) Nucleic Acids Res , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4
  • 40
    • 0032728266 scopus 로고    scopus 로고
    • Expression of the AMP-activated protein kinase beta1 and beta2 subunits in skelet al muscle
    • Chen Z, Heierhorst J, Mann RJ, Mitchelhill KI, Michell BJ, Witters LA et al. Expression of the AMP-activated protein kinase beta1 and beta2 subunits in skelet al muscle. FEBS Lett 1999; 460: 343-348.
    • (1999) FEBS Lett , vol.460 , pp. 343-348
    • Chen, Z.1    Heierhorst, J.2    Mann, R.J.3    Mitchelhill, K.I.4    Michell, B.J.5    Witters, L.A.6
  • 41
    • 0029946455 scopus 로고    scopus 로고
    • Isoformspecific purification and substrate specificity of the 5¢-AMP-activated protein kinase
    • Michell BJ, Stapleton D, Mitchelhill KI, House CM, Katsis F, Witters LA et al. Isoformspecific purification and substrate specificity of the 5¢-AMP-activated protein kinase. J Biol Chem 1996; 271: 28445-28450.
    • (1996) J Biol Chem , vol.271 , pp. 28445-28450
    • Michell, B.J.1    Stapleton, D.2    Mitchelhill, K.I.3    House, C.M.4    Katsis, F.5    Witters, L.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.